BCB420 Assignment 2

Assignment 2: Differential Gene Expression and Preliminary ORA

Introduction: Preliminary Data Exploration

Description of Dataset

GEO Accession Number: GSE232825

Dataset Title: Transcriptomics of Chronic Active Antibody-Mediated Rejection of Human Kidney Allografts and Identification of Intragraft Overexpression of Natural Kill Cell Cytotoxicity Gene Set

Paper title: Transcriptomic signatures of chronic active antibody-mediated rejection deciphered by RNA sequencing of human kidney allografts[1].

In this assignment, I will be conducting differential gene expression analysis on the dataset normalized and processed in the previous assignment (dataset source and paper title has been described above). In A1, I utilized GEO’s new NCBI-Generated RNA-seq count data feature to download the raw counts data from GEO Accession Number GSE232825. I retrieved the code to download the NCBI-generated RNA-seq raw count data from the GEO Webpage for this Series https://www.ncbi.nlm.nih.gov/geo/geo2r/?acc=GSE232825, (click the R Script tab).

Data Normalization and Separation Summary

Summary Statistics

First, we load the data in from the output of A1. We also load in the table specifying the disease type (caABMR vs. No Rejection vs. TCMR) for each sample. Note: my initial submission of A1 did not include code to save this counts data to my repository, and so A1 has been modified to include code for this.

processed_counts <- readRDS("Data/Processed/final_counts_GSE232825.rds")
sample_type <- read.csv("Data/Processed/accession_mapping.csv")

# Defining functions for visualizing the spread of data

# Box plot (as shown in lecture)
plot_boxplot <- function(counts) {
  data2plot <- log2(counts)
  boxplot(data2plot, xlab = "Samples", ylab = "log2 TPM",
          las = 2, cex = 0.5, cex.lab = 0.5,
          cex.axis = 0.5, main = "RNASeq Samples")
  abline(h = median(apply(data2plot, 2, median)),
         col = "green", lwd = 0.6, lty = "dashed")
}

# Density plot (as shown in lecture)
density_plot <- function(counts) {
  data2plot <- log2(counts)
  counts_density <- apply(log2(counts), 2, density)
  # Calculate the limits across all the samples
  xlim <- 0; ylim <- 0
  for (i in 1:length(counts_density)) {
  xlim <- range(c(xlim, counts_density[[i]]$x));
  ylim <- range(c(ylim, counts_density[[i]]$y))
  }
  cols <- rainbow(length(counts_density))
  ltys <- rep(1, length(counts_density))
  # Plot the first density plot to initialize the plot
  plot(counts_density[[1]], xlim=xlim, ylim=ylim, type="n", ylab="Smoothing density of log2-CPM", main="", cex.lab = 0.85)
  # Plot each line
  for (i in 1:length(counts_density)) {
    lines(counts_density[[i]], col=cols[i], lty=ltys[i])
  }
  # Create legend
  legend("topright", colnames(data2plot),
  col=cols, lty=ltys, cex=0.75,
  border ="blue", text.col = "green4",
  merge = TRUE, bg = "gray90")
}

plot_boxplot(processed_counts)

Figure 1. Box-and-whisker plot showing mean log2(TPM) values of each sample, with their standard deviation.

density_plot(processed_counts)

Figure 2. Density plot showing spread of normalized count data.

From the plots above, we see that the means of the counts for each sample are aligned, and that the counts approximate a normal distribution. Therefore, we can proceed with downstream analysis as our count data appear to be sufficiently normalized.

Data Separation

Before we move on, we would also like to see how our samples separate based on gene expression. To this end, we will use edgeR’s DGElist() function and limma’s plotMDS() function to create an MDS plot that visualizes the separation of counts data from each sample based on gene expression [3].

d = edgeR::DGEList(counts=processed_counts, group=sample_type$treatment)

limma::plotMDS(d,labels=NULL, pch = 1, 
               col = c("darkgreen","blue", "red", "yellow")[factor(sample_type$treatment)])
legend("topright", legend=levels(factor(sample_type$treatment)), 
       pch=c(1), col= c("darkgreen","blue", "red", "yellow"), title="Disease State", 
       bty = 'n', cex = 0.75)

Figure 3. MDS plot showing separation of samples, coloured by disease state.

Subsetting the Count Matrix to caABMR and Non-Rejection Groups

Because we want to focus our analysis to caABMR vs. Non-Rejection, we will subset our counts matrix and sample metadata to only include these samples.

counts_caABMR_healthy <- processed_counts[, sample_type$sample_number[which(sample_type$treatment == "caABMR" | sample_type$treatment == "No Rejection")]]
samples_caABMR_healthy <- sample_type[which(sample_type$treatment == "caABMR" | sample_type$treatment == "No Rejection"), ]

Differential Expression Analysis with edgeR

We will now conduct differential expression analysis using EdgeR’s [2]. We picked edgeR over limma because edgeR is more suited for handling RNA-seq data as it models RNA-seq counts using a negative binomial distribution, which is closer to true RNA-seq count distribution. Our model design only includes a single coefficient for the “treatment”/“genotype” variable (they are identical and interchangeable in our sample table), since we saw in our MDS plot that the samples separate by treatment type (caABMR vs. non-rejection). While it would be good to include other potentially confounding variables in our model, such as time after transplant when the biopsy samples were taken, this information is not available in our sample information table. Further analysis of the data can include a comprehensive analysis of factors potentially contributing to observed gene expression differences, but for now, we will focus on sample separation based on disease state.

We use the quasi-likelihood F-test (glmQLFit() and glmQLFTest()) to conduct DE analysis, since it better reflects the uncertainty in calculated dispersion values of genes and therefore produces more robust results. [4] This step calculates p-values for each differentially expressed gene identified.

model_design <- model.matrix(~ samples_caABMR_healthy$genotype)
d <- edgeR::DGEList(counts=counts_caABMR_healthy, group = samples_caABMR_healthy$genotype)
d <- edgeR::estimateDisp(d, model_design)

fit <- edgeR::glmQLFit(d, model_design)

qlf.caABMR_vs_healthy <- edgeR::glmQLFTest(fit, coef='samples_caABMR_healthy$genotypeNo Rejection')
knitr::kable(edgeR::topTags(qlf.caABMR_vs_healthy), type="html",row.names =
TRUE)

logFC logCPM F PValue FDR MIR155HG -1.944672 1.762809 187.9515 0 0 TBX21 -2.559097 1.996923 138.6067 0 0 FPR1 -1.926327 1.892903 139.5003 0 0 CCL3 -2.433075 1.765311 134.8333 0 0 LYPD5 -2.743903 2.057407 132.3472 0 0 CLEC12A -2.736912 2.004682 129.6078 0 0 CD244 -2.377980 1.781168 126.5323 0 0 PYHIN1 -2.889147 2.011981 125.3946 0 0 SH2D2A -2.230634 1.988716 126.2481 0 0 FCRL6 -2.415686 2.000225 123.5064 0 0

x 1 BH

x 1 samples_caABMR_healthy$genotypeNo Rejection

x 1 glm

We then adjusted p-values using the Benjamini-Hochberg (BH) method for multiple testing correction, which reduces the false discovery rate (FDR), and sorted by p value.

qlf_output_hits <- edgeR::topTags(qlf.caABMR_vs_healthy, sort.by = "PValue", adjust.method = "BH", n = nrow(counts_caABMR_healthy))

We can see that there are length(which(qlf_output_hits$table$PValue < 0.05)) genes which are statistically significant if we use a cutoff of pval < 0.05, while there are fewer genes (length(which(qlf_output_hits$table$FDR < 0.05))) if we use the BH method to correct p values and set a threshold of FDR < 0.05.

Volcano Plots

Next, we plot volcano plots to visualize the top 30 differentially expressed genes in caABMR vs. no rejection. To plot the points, we use ggplot2, ggrepel, and RColorBrewer for coloring [7].

Note: We calculate a “neglogFC” to produce our plot so that genes upregulated in the caABMR group is shown to the right of the plot.

library(RColorBrewer)
library(ggrepel)

## Loading required package: ggplot2

qlf_output_hits$table$neglogFC <- - qlf_output_hits$table$logFC

qlf_output_hits$table$DE <- "No"
qlf_output_hits$table$DE[qlf_output_hits$table$neglogFC > 0.6 & qlf_output_hits$table$FDR < 0.05] <- "UP"
qlf_output_hits$table$DE[qlf_output_hits$table$neglogFC < -0.6 & qlf_output_hits$table$FDR < 0.05] <- "DOWN"

top30degs <- rownames(head(qlf_output_hits$table[order(qlf_output_hits$table$FDR), ], 30))
nk.genes <- c("KLRB1", "KLRD1", "KLRC1", "CD160", "GZMB", "GNLY")

qlf_output_hits$table$top30 <- ifelse(rownames(qlf_output_hits$table) %in% c(top30degs, nk.genes), rownames(qlf_output_hits$table), NA)

ggplot2::ggplot(data = qlf_output_hits, aes(x = neglogFC, y = -log10(FDR), col = DE, label = top30)) + 
  geom_vline(xintercept = c(-0.6, 0.6), col = "gray", linetype = "dashed") + 
  geom_hline(yintercept = -log10(0.05), col = "gray", linetype = "dashed") + 
  geom_point() + 
  scale_color_manual(values = c("blue", "grey", "red"), 
                     labels = c("Downregulated", "Not significant", "Upregulated")) + 
  geom_text_repel(max.overlaps = Inf)

## Warning: Removed 18297 rows containing missing values or values outside the scale range
## (`geom_text_repel()`).

Figure 4. Volcano plot showing differentially expressed genes between caABMR and non-rejecting samples, with the top 30 DE genes (by p value) labelled.

Notably, we see that several chemokines involved in inflammatory response (CCL3, CCL4), cytokine receptors (IL12 receptor IL12RB) known to contribute to anti-transplant immune response are upregulated in the caABMR group versus non-rejecting tissue.

Apart from the top 30 differentially expressed genes, I also included key NK genes (KLRB1, KLRC1, KLRD1, CD160) and cytotoxic effectors (GZMB, GNLY) in my volcano plot, since these were shown to be upregulated in caABMR vs. non-rejection by the authors [1]. We see that in our results, these genes are significantly upregulated in the caABMR group, indicating that there is an activation of NK cytotoxic pathways during caABMR.

It is also noteworthy that most of the top statistically significant genes are upregulated in caABMR, and not in no-rejection (none of the top 30 DE genes belong to the no-rejection group). This could suggest that the altered immmune response contributing to caABMR mostly involves the upregulation of genes and involves downregulation to a lesser extent.

Heatmap Representation

Next, we will plot a heatmap of our top differentially expressed genes to observe whether our samples cluster according to disease state.

library(ComplexHeatmap)

## Loading required package: grid

## ========================================
## ComplexHeatmap version 2.20.0
## Bioconductor page: http://bioconductor.org/packages/ComplexHeatmap/
## Github page: https://github.com/jokergoo/ComplexHeatmap
## Documentation: http://jokergoo.github.io/ComplexHeatmap-reference
## 
## If you use it in published research, please cite either one:
## - Gu, Z. Complex Heatmap Visualization. iMeta 2022.
## - Gu, Z. Complex heatmaps reveal patterns and correlations in multidimensional 
##     genomic data. Bioinformatics 2016.
## 
## 
## The new InteractiveComplexHeatmap package can directly export static 
## complex heatmaps into an interactive Shiny app with zero effort. Have a try!
## 
## This message can be suppressed by:
##   suppressPackageStartupMessages(library(ComplexHeatmap))
## ========================================

library(circlize)

## ========================================
## circlize version 0.4.16
## CRAN page: https://cran.r-project.org/package=circlize
## Github page: https://github.com/jokergoo/circlize
## Documentation: https://jokergoo.github.io/circlize_book/book/
## 
## If you use it in published research, please cite:
## Gu, Z. circlize implements and enhances circular visualization
##   in R. Bioinformatics 2014.
## 
## This message can be suppressed by:
##   suppressPackageStartupMessages(library(circlize))
## ========================================

heatmap_matrix <- counts_caABMR_healthy

top_hits <- rownames(qlf_output_hits$table)[qlf_output_hits$table$PValue<0.05]

heatmap_matrix_tophits <- t(scale(t(heatmap_matrix[which(rownames(heatmap_matrix)
                                                         %in% c(top_hits)), ])))

if(min(heatmap_matrix_tophits) == 0){
  heatmap_col = colorRamp2(c( 0, max(heatmap_matrix_tophits)), c( "white", "red"))
} else {
  heatmap_col = colorRamp2(c(min(heatmap_matrix_tophits), 0,
                             max(heatmap_matrix_tophits)), c("blue", "white", "red"))}

unique_patients <- unique(samples_caABMR_healthy$title)
unique_patientscolors <- rainbow(n = length(unique_patients))
names(unique_patientscolors) <- unique_patients
unique_treatments <- unique(samples_caABMR_healthy$treatment)
unique_treatmentcols <- rainbow(n = length(unique_treatments))
names(unique_treatmentcols) <- unique_treatments

ha_pat <- HeatmapAnnotation(df = data.frame(
  patients = samples_caABMR_healthy$title,
  treatments = samples_caABMR_healthy$treatment), 
  col = list(
    patients = unique_patientscolors,
    treatments = unique_treatmentcols), 
  show_legend = TRUE)

current_heatmap <- Heatmap(as.matrix(heatmap_matrix_tophits), 
                           top_annotation = ha_pat, 
                           cluster_rows = TRUE, 
                           cluster_columns = TRUE, 
                           show_row_dend = TRUE, 
                           show_column_dend = TRUE, 
                           col=heatmap_col, 
                           show_column_names = FALSE, 
                           show_row_names = FALSE, 
                           show_heatmap_legend = TRUE, 
                           column_title = ("Top hits caABMR vs Non-rejection"))

## `use_raster` is automatically set to TRUE for a matrix with more than
## 2000 rows. You can control `use_raster` argument by explicitly setting
## TRUE/FALSE to it.
## 
## Set `ht_opt$message = FALSE` to turn off this message.

current_heatmap

Figure 5. Heatmap representation of differentially expressed genes, with dendograms showing clustering of cells and genes.

We see that our heatmap gives us mixed results: on one hand, broadly speaking, there is a clustering of certain genes that are distinctly upregulated in the caABMR group, while there is a smaller set of genes that distinctly mark the non-rejection samples. However, there is a group of samples in the caABMR group which seem to upregulate a distinct set of genes and do NOT upregulate most of the genes in the caABMR upregulated set and, judging by the dendogram showing sample clustering, seem to cluster with some of the non rejection samples. It would be interesting to assess whether this clustering pattern correlates with any other factor that we may have not looked into.

Preliminary ORA

We next wanted to conduct some preliminary thresholded ORA to observe if there is an enrichment in specific pathway gene sets in our upregulated/downregulated/combined genes.

For ORA, we chose to use gprofiler2 since it contains up-to-date gene sets [8]. This provides an R interface to the web-based tool GProfiler [9]. We focus on the GO:BP and KEGG pathways since they contain important immune-related pathways and disease-associated pathways that might be relevant for our analysis, and GO:MF because they might shed light on specific molecular pathways that mediate ABMR.

Note:

1. We use a threshold of |logFC| > 1.1 to find significantly upregulated/downregulated genes. The reason we use 1.1 and not 0 is because we want to focus on genes that are differentially expressed at a strong enough magnitude since these are more likely to have stronger biological effects.

2. We call genes with logFC < - 1.1 “upregulated” because these are the genes that are downregulated in the “No Rejection” samples and are therefore upregulated in the caABMR group, and I want to set the caABMR samples as my “positive” set.

# getting sets of upregulated and downregulated genes and combined gene set
upregulated_genes <- rownames(qlf_output_hits$table[
  which(qlf_output_hits$table$PValue < 0.05 & qlf_output_hits$table$logFC < -1.1),])
downregulated_genes <- rownames(qlf_output_hits$table[
  which(qlf_output_hits$table$PValue < 0.05 & qlf_output_hits$table$logFC > 1.1),])
combined_genes <- rownames(qlf_output_hits$table[
  which(qlf_output_hits$table$PValue < 0.05 & (qlf_output_hits$table$logFC < -1.1 |
                                                 qlf_output_hits$table$logFC > 1.1)),])

Combined Gene Set

library(dplyr)

## 
## Attaching package: 'dplyr'

## The following objects are masked from 'package:stats':
## 
##     filter, lag

## The following objects are masked from 'package:base':
## 
##     intersect, setdiff, setequal, union

gprofiler_output <- gprofiler2::gost(query = combined_genes, 
                                     significant = TRUE,
                                     exclude_iea = TRUE,
                                     correction_method = "fdr", 
                                     organism = "hsapiens", 
                                     source = c("GO:BP", "GO:MF", "KEGG"))

gprofiler_comb <- as.data.frame(gprofiler_output$result)
knitr::kable(gprofiler_comb, type="html") %>% 
  kableExtra::scroll_box(width = "600px", height = "200px")

query	significant	p_value	term_size	query_size	intersection_size	precision	recall	term_id	source	term_name	effective_domain_size	source_order	parents
query_1	TRUE	0.0000000	2117	912	445	0.4879386	0.2102031	GO:0002376	GO:BP	immune system process	16175	906	GO:0008150
query_1	TRUE	0.0000000	1519	912	377	0.4133772	0.2481896	GO:0006955	GO:BP	immune response	16175	2586	GO:00023….
query_1	TRUE	0.0000000	1238	912	274	0.3004386	0.2213247	GO:0002682	GO:BP	regulation of immune system process	16175	1200	GO:00023….
query_1	TRUE	0.0000000	699	912	202	0.2214912	0.2889843	GO:0045321	GO:BP	leukocyte activation	16175	11356	GO:00017….
query_1	TRUE	0.0000000	820	912	218	0.2390351	0.2658537	GO:0001775	GO:BP	cell activation	16175	440	GO:00099….
query_1	TRUE	0.0000000	881	912	219	0.2401316	0.2485812	GO:0002684	GO:BP	positive regulation of immune system process	16175	1202	GO:00023….
query_1	TRUE	0.0000000	1364	912	269	0.2949561	0.1972141	GO:0006952	GO:BP	defense response	16175	2583	GO:0006950
query_1	TRUE	0.0000000	756	912	197	0.2160088	0.2605820	GO:0050776	GO:BP	regulation of immune response	16175	13250	GO:00026….
query_1	TRUE	0.0000000	569	912	169	0.1853070	0.2970123	GO:0046649	GO:BP	lymphocyte activation	16175	12286	GO:0045321
query_1	TRUE	0.0000000	536	912	160	0.1754386	0.2985075	GO:0002252	GO:BP	immune effector process	16175	784	GO:0002376
query_1	TRUE	0.0000000	7207	912	664	0.7280702	0.0921326	GO:0050896	GO:BP	response to stimulus	16175	13339	GO:0008150
query_1	TRUE	0.0000000	627	912	168	0.1842105	0.2679426	GO:0050778	GO:BP	positive regulation of immune response	16175	13252	GO:00026….
query_1	TRUE	0.0000000	468	912	141	0.1546053	0.3012821	GO:0050865	GO:BP	regulation of cell activation	16175	13313	GO:00017….
query_1	TRUE	0.0000000	421	912	131	0.1436404	0.3111639	GO:0002694	GO:BP	regulation of leukocyte activation	16175	1212	GO:00026….
query_1	TRUE	0.0000000	406	912	126	0.1381579	0.3103448	GO:0042110	GO:BP	T cell activation	16175	9970	GO:0046649
query_1	TRUE	0.0000000	334	912	114	0.1250000	0.3413174	GO:0002250	GO:BP	adaptive immune response	16175	782	GO:0006955
query_1	TRUE	0.0000000	475	912	133	0.1458333	0.2800000	GO:0002253	GO:BP	activation of immune response	16175	785	GO:00023….
query_1	TRUE	0.0000000	369	912	116	0.1271930	0.3143631	GO:0051249	GO:BP	regulation of lymphocyte activation	16175	13596	GO:00026….
query_1	TRUE	0.0000000	1724	912	261	0.2861842	0.1513921	GO:0009605	GO:BP	response to external stimulus	16175	3533	GO:0050896
query_1	TRUE	0.0000000	334	912	109	0.1195175	0.3263473	GO:0002443	GO:BP	leukocyte mediated immunity	16175	966	GO:0002252
query_1	TRUE	0.0000000	437	912	124	0.1359649	0.2837529	GO:0002764	GO:BP	immune response-regulating signaling pathway	16175	1275	GO:00071….
query_1	TRUE	0.0000000	1941	912	278	0.3048246	0.1432251	GO:0048584	GO:BP	positive regulation of response to stimulus	16175	12855	GO:00485….
query_1	TRUE	0.0000000	416	912	119	0.1304825	0.2860577	GO:0002757	GO:BP	immune response-activating signaling pathway	16175	1268	GO:00022….
query_1	TRUE	0.0000000	2272	912	301	0.3300439	0.1324824	GO:0051239	GO:BP	regulation of multicellular organismal process	16175	13589	GO:00325….
query_1	TRUE	0.0000000	594	912	139	0.1524123	0.2340067	GO:0006954	GO:BP	inflammatory response	16175	2585	GO:0006952
query_1	TRUE	0.0000000	276	912	95	0.1041667	0.3442029	GO:0002460	GO:BP	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	16175	983	GO:0002250
query_1	TRUE	0.0000000	287	912	95	0.1041667	0.3310105	GO:0002768	GO:BP	immune response-regulating cell surface receptor signaling pathway	16175	1279	GO:00027….
query_1	TRUE	0.0000000	265	912	91	0.0997807	0.3433962	GO:0002429	GO:BP	immune response-activating cell surface receptor signaling pathway	16175	952	GO:00027….
query_1	TRUE	0.0000000	1109	912	191	0.2094298	0.1722272	GO:0043207	GO:BP	response to external biotic stimulus	16175	10576	GO:00096….
query_1	TRUE	0.0000000	1109	912	191	0.2094298	0.1722272	GO:0051707	GO:BP	response to other organism	16175	13904	GO:00432….
query_1	TRUE	0.0000000	1143	912	194	0.2127193	0.1697288	GO:0009607	GO:BP	response to biotic stimulus	16175	3535	GO:0050896
query_1	TRUE	0.0000000	269	912	91	0.0997807	0.3382900	GO:0002449	GO:BP	lymphocyte mediated immunity	16175	972	GO:0002443
query_1	TRUE	0.0000000	634	912	138	0.1513158	0.2176656	GO:0001817	GO:BP	regulation of cytokine production	16175	474	GO:00018….
query_1	TRUE	0.0000000	638	912	138	0.1513158	0.2163009	GO:0001816	GO:BP	cytokine production	16175	473	GO:00104….
query_1	TRUE	0.0000000	2237	912	286	0.3135965	0.1278498	GO:0007166	GO:BP	cell surface receptor signaling pathway	16175	2730	GO:0007165
query_1	TRUE	0.0000000	3347	912	369	0.4046053	0.1102480	GO:0048583	GO:BP	regulation of response to stimulus	16175	12854	GO:00507….
query_1	TRUE	0.0000000	934	912	169	0.1853070	0.1809422	GO:0098542	GO:BP	defense response to other organism	16175	18794	GO:00069….
query_1	TRUE	0.0000000	855	912	160	0.1754386	0.1871345	GO:0140546	GO:BP	defense response to symbiont	16175	19820	GO:0098542
query_1	TRUE	0.0000000	324	912	96	0.1052632	0.2962963	GO:0007159	GO:BP	leukocyte cell-cell adhesion	16175	2723	GO:0098609
query_1	TRUE	0.0000000	434	912	111	0.1217105	0.2557604	GO:0002521	GO:BP	leukocyte differentiation	16175	1043	GO:00300….
query_1	TRUE	0.0000000	1238	912	197	0.2160088	0.1591276	GO:0044419	GO:BP	biological process involved in interspecies interaction between organisms	16175	10998	GO:0008150
query_1	TRUE	0.0000000	1259	912	197	0.2160088	0.1564734	GO:0051240	GO:BP	positive regulation of multicellular organismal process	16175	13590	GO:00325….
query_1	TRUE	0.0000000	284	912	88	0.0964912	0.3098592	GO:0050863	GO:BP	regulation of T cell activation	16175	13311	GO:00421….
query_1	TRUE	0.0000000	4773	912	458	0.5021930	0.0959564	GO:0007165	GO:BP	signal transduction	16175	2729	GO:00071….
query_1	TRUE	0.0000000	3079	912	341	0.3739035	0.1107502	GO:0006950	GO:BP	response to stress	16175	2582	GO:0050896
query_1	TRUE	0.0000000	290	912	87	0.0953947	0.3000000	GO:0050867	GO:BP	positive regulation of cell activation	16175	13315	GO:00017….
query_1	TRUE	0.0000000	357	912	96	0.1052632	0.2689076	GO:1903131	GO:BP	mononuclear cell differentiation	16175	22787	GO:0002521
query_1	TRUE	0.0000000	275	912	84	0.0921053	0.3054545	GO:0002696	GO:BP	positive regulation of leukocyte activation	16175	1214	GO:00026….
query_1	TRUE	0.0000000	158	912	64	0.0701754	0.4050633	GO:0050851	GO:BP	antigen receptor-mediated signaling pathway	16175	13299	GO:0002429
query_1	TRUE	0.0000000	5189	912	476	0.5219298	0.0917325	GO:0007154	GO:BP	cell communication	16175	2718	GO:0009987
query_1	TRUE	0.0000000	5175	912	475	0.5208333	0.0917874	GO:0023052	GO:BP	signaling	16175	6640	GO:0050789
query_1	TRUE	0.0000000	884	912	154	0.1688596	0.1742081	GO:0032101	GO:BP	regulation of response to external stimulus	16175	7365	GO:00096….
query_1	TRUE	0.0000000	403	912	100	0.1096491	0.2481390	GO:0001819	GO:BP	positive regulation of cytokine production	16175	476	GO:00018….
query_1	TRUE	0.0000000	287	912	84	0.0921053	0.2926829	GO:1903037	GO:BP	regulation of leukocyte cell-cell adhesion	16175	22717	GO:00071….
query_1	TRUE	0.0000000	745	912	139	0.1524123	0.1865772	GO:0098609	GO:BP	cell-cell adhesion	16175	18805	GO:0007155
query_1	TRUE	0.0000000	236	912	76	0.0833333	0.3220339	GO:0070661	GO:BP	leukocyte proliferation	16175	16242	GO:0008283
query_1	TRUE	0.0000000	638	912	127	0.1392544	0.1990596	GO:0030097	GO:BP	hemopoiesis	16175	6675	GO:0048468
query_1	TRUE	0.0000000	386	912	97	0.1063596	0.2512953	GO:0022407	GO:BP	regulation of cell-cell adhesion	16175	6598	GO:00301….
query_1	TRUE	0.0000000	208	912	71	0.0778509	0.3413462	GO:0046651	GO:BP	lymphocyte proliferation	16175	12287	GO:00329….
query_1	TRUE	0.0000000	383	912	96	0.1052632	0.2506527	GO:0002683	GO:BP	negative regulation of immune system process	16175	1201	GO:00023….
query_1	TRUE	0.0000000	1201	912	182	0.1995614	0.1515404	GO:0007155	GO:BP	cell adhesion	16175	2719	GO:0009987
query_1	TRUE	0.0000000	276	912	81	0.0888158	0.2934783	GO:0002697	GO:BP	regulation of immune effector process	16175	1215	GO:00022….
query_1	TRUE	0.0000000	211	912	71	0.0778509	0.3364929	GO:0032943	GO:BP	mononuclear cell proliferation	16175	7928	GO:0070661
query_1	TRUE	0.0000000	654	912	125	0.1370614	0.1911315	GO:0031347	GO:BP	regulation of defense response	16175	7138	GO:00069….
query_1	TRUE	0.0000000	721	912	132	0.1447368	0.1830791	GO:0045087	GO:BP	innate immune response	16175	11270	GO:00069….
query_1	TRUE	0.0000000	249	912	75	0.0822368	0.3012048	GO:0051251	GO:BP	positive regulation of lymphocyte activation	16175	13598	GO:00026….
query_1	TRUE	0.0000000	190	912	65	0.0712719	0.3421053	GO:0070663	GO:BP	regulation of leukocyte proliferation	16175	16244	GO:00421….
query_1	TRUE	0.0000000	169	912	61	0.0668860	0.3609467	GO:0050670	GO:BP	regulation of lymphocyte proliferation	16175	13204	GO:00329….
query_1	TRUE	0.0000000	171	912	61	0.0668860	0.3567251	GO:0032944	GO:BP	regulation of mononuclear cell proliferation	16175	7929	GO:00329….
query_1	TRUE	0.0000000	257	912	74	0.0811404	0.2879377	GO:0022409	GO:BP	positive regulation of cell-cell adhesion	16175	6600	GO:00224….
query_1	TRUE	0.0000000	5277	912	466	0.5109649	0.0883078	GO:0032501	GO:BP	multicellular organismal process	16175	7611	GO:0008150
query_1	TRUE	0.0000000	625	912	118	0.1293860	0.1888000	GO:1901652	GO:BP	response to peptide	16175	21619	GO:0042221
query_1	TRUE	0.0000000	625	912	118	0.1293860	0.1888000	GO:0034097	GO:BP	response to cytokine	16175	8408	GO:1901652
query_1	TRUE	0.0000000	215	912	67	0.0734649	0.3116279	GO:1903039	GO:BP	positive regulation of leukocyte cell-cell adhesion	16175	22719	GO:00071….
query_1	TRUE	0.0000000	297	912	78	0.0855263	0.2626263	GO:0030098	GO:BP	lymphocyte differentiation	16175	6676	GO:00466….
query_1	TRUE	0.0000000	555	912	108	0.1184211	0.1945946	GO:0071345	GO:BP	cellular response to cytokine stimulus	16175	16597	GO:0034097
query_1	TRUE	0.0000000	216	912	65	0.0712719	0.3009259	GO:0002366	GO:BP	leukocyte activation involved in immune response	16175	898	GO:00022….
query_1	TRUE	0.0000000	5229	912	456	0.5000000	0.0872060	GO:0048518	GO:BP	positive regulation of biological process	16175	12801	GO:00081….
query_1	TRUE	0.0000000	531	912	104	0.1140351	0.1958569	GO:0032103	GO:BP	positive regulation of response to external stimulus	16175	7367	GO:00096….
query_1	TRUE	0.0000000	221	912	65	0.0712719	0.2941176	GO:0002263	GO:BP	cell activation involved in immune response	16175	795	GO:00017….
query_1	TRUE	0.0000000	195	912	61	0.0668860	0.3128205	GO:0050870	GO:BP	positive regulation of T cell activation	16175	13318	GO:00421….
query_1	TRUE	0.0000000	5898	912	494	0.5416667	0.0837572	GO:0051716	GO:BP	cellular response to stimulus	16175	13909	GO:00099….
query_1	TRUE	0.0000000	304	912	76	0.0833333	0.2500000	GO:0050900	GO:BP	leukocyte migration	16175	13342	GO:00023….
query_1	TRUE	0.0000000	622	912	112	0.1228070	0.1800643	GO:0030155	GO:BP	regulation of cell adhesion	16175	6688	GO:00071….
query_1	TRUE	0.0000000	147	912	52	0.0570175	0.3537415	GO:0019724	GO:BP	B cell mediated immunity	16175	6019	GO:00024….
query_1	TRUE	0.0000000	419	912	88	0.0964912	0.2100239	GO:0019221	GO:BP	cytokine-mediated signaling pathway	16175	5598	GO:00071….
query_1	TRUE	0.0000000	451	912	91	0.0997807	0.2017738	GO:0002831	GO:BP	regulation of response to biotic stimulus	16175	1341	GO:00096….
query_1	TRUE	0.0000000	206	912	59	0.0646930	0.2864078	GO:0030217	GO:BP	T cell differentiation	16175	6725	GO:00300….
query_1	TRUE	0.0000000	142	912	49	0.0537281	0.3450704	GO:0016064	GO:BP	immunoglobulin mediated immune response	16175	5095	GO:0019724
query_1	TRUE	0.0000000	373	912	80	0.0877193	0.2144772	GO:0045785	GO:BP	positive regulation of cell adhesion	16175	11617	GO:00071….
query_1	TRUE	0.0000000	125	912	45	0.0493421	0.3600000	GO:0046631	GO:BP	alpha-beta T cell activation	16175	12268	GO:0042110
query_1	TRUE	0.0000000	795	912	122	0.1337719	0.1534591	GO:0051241	GO:BP	negative regulation of multicellular organismal process	16175	13591	GO:00325….
query_1	TRUE	0.0000000	386	912	80	0.0877193	0.2072539	GO:0045088	GO:BP	regulation of innate immune response	16175	11271	GO:00028….
query_1	TRUE	0.0000000	55	912	31	0.0339912	0.5636364	GO:0050853	GO:BP	B cell receptor signaling pathway	16175	13301	GO:0050851
query_1	TRUE	0.0000000	423	912	84	0.0921053	0.1985816	GO:0031349	GO:BP	positive regulation of defense response	16175	7140	GO:00069….
query_1	TRUE	0.0000000	228	912	60	0.0657895	0.2631579	GO:1902105	GO:BP	regulation of leukocyte differentiation	16175	22019	GO:00025….
query_1	TRUE	0.0000000	197	912	55	0.0603070	0.2791878	GO:0042113	GO:BP	B cell activation	16175	9971	GO:0046649
query_1	TRUE	0.0000000	119	912	43	0.0471491	0.3613445	GO:0070665	GO:BP	positive regulation of leukocyte proliferation	16175	16246	GO:00082….
query_1	TRUE	0.0000000	1546	912	184	0.2017544	0.1190168	GO:0141124	GO:BP	intracellular signaling cassette	16175	20031	GO:0035556
query_1	TRUE	0.0000000	104	912	40	0.0438596	0.3846154	GO:0050671	GO:BP	positive regulation of lymphocyte proliferation	16175	13205	GO:00329….
query_1	TRUE	0.0000000	167	912	50	0.0548246	0.2994012	GO:0002274	GO:BP	myeloid leukocyte activation	16175	806	GO:0045321
query_1	TRUE	0.0000000	105	912	40	0.0438596	0.3809524	GO:0032946	GO:BP	positive regulation of mononuclear cell proliferation	16175	7931	GO:00329….
query_1	TRUE	0.0000000	146	912	46	0.0504386	0.3150685	GO:0050866	GO:BP	negative regulation of cell activation	16175	13314	GO:00017….
query_1	TRUE	0.0000000	140	912	45	0.0493421	0.3214286	GO:0042098	GO:BP	T cell proliferation	16175	9965	GO:00421….
query_1	TRUE	0.0000000	168	912	49	0.0537281	0.2916667	GO:0001906	GO:BP	cell killing	16175	524	GO:0009987
query_1	TRUE	0.0000000	192	912	52	0.0570175	0.2708333	GO:0002699	GO:BP	positive regulation of immune effector process	16175	1217	GO:00022….
query_1	TRUE	0.0000000	339	912	70	0.0767544	0.2064897	GO:0002833	GO:BP	positive regulation of response to biotic stimulus	16175	1343	GO:00028….
query_1	TRUE	0.0000000	127	912	42	0.0460526	0.3307087	GO:0002695	GO:BP	negative regulation of leukocyte activation	16175	1213	GO:00026….
query_1	TRUE	0.0000000	188	912	51	0.0559211	0.2712766	GO:0071674	GO:BP	mononuclear cell migration	16175	16847	GO:0050900
query_1	TRUE	0.0000000	98	912	37	0.0405702	0.3775510	GO:0019882	GO:BP	antigen processing and presentation	16175	6060	GO:0002376
query_1	TRUE	0.0000000	319	912	67	0.0734649	0.2100313	GO:0045089	GO:BP	positive regulation of innate immune response	16175	11272	GO:00028….
query_1	TRUE	0.0000000	177	912	49	0.0537281	0.2768362	GO:0002703	GO:BP	regulation of leukocyte mediated immunity	16175	1221	GO:00024….
query_1	TRUE	0.0000000	945	912	128	0.1403509	0.1354497	GO:0010628	GO:BP	positive regulation of gene expression	16175	4274	GO:00104….
query_1	TRUE	0.0000000	273	912	61	0.0668860	0.2234432	GO:0060326	GO:BP	cell chemotaxis	16175	14538	GO:00069….
query_1	TRUE	0.0000000	1150	912	145	0.1589912	0.1260870	GO:0080134	GO:BP	regulation of response to stress	16175	17816	GO:00069….
query_1	TRUE	0.0000000	443	912	80	0.0877193	0.1805869	GO:0009617	GO:BP	response to bacterium	16175	3543	GO:0051707
query_1	TRUE	0.0000000	114	912	39	0.0427632	0.3421053	GO:0050852	GO:BP	T cell receptor signaling pathway	16175	13300	GO:0050851
query_1	TRUE	0.0000000	1392	912	164	0.1798246	0.1178161	GO:0008283	GO:BP	cell population proliferation	16175	3150	GO:0009987
query_1	TRUE	0.0000000	1221	912	150	0.1644737	0.1228501	GO:0042127	GO:BP	regulation of cell population proliferation	16175	9981	GO:00082….
query_1	TRUE	0.0000000	375	912	72	0.0789474	0.1920000	GO:0006935	GO:BP	chemotaxis	16175	2574	GO:00422….
query_1	TRUE	0.0000000	375	912	72	0.0789474	0.1920000	GO:0042330	GO:BP	taxis	16175	10096	GO:00096….
query_1	TRUE	0.0000000	200	912	51	0.0559211	0.2550000	GO:0030595	GO:BP	leukocyte chemotaxis	16175	6861	GO:00509….
query_1	TRUE	0.0000000	4915	912	405	0.4440789	0.0824008	GO:0048522	GO:BP	positive regulation of cellular process	16175	12805	GO:00099….
query_1	TRUE	0.0000000	299	912	63	0.0690789	0.2107023	GO:0050727	GO:BP	regulation of inflammatory response	16175	13226	GO:00069….
query_1	TRUE	0.0000000	106	912	37	0.0405702	0.3490566	GO:0001909	GO:BP	leukocyte mediated cytotoxicity	16175	526	GO:00019….
query_1	TRUE	0.0000000	309	912	64	0.0701754	0.2071197	GO:1903706	GO:BP	regulation of hemopoiesis	16175	23220	GO:00026….
query_1	TRUE	0.0000000	152	912	44	0.0482456	0.2894737	GO:0071219	GO:BP	cellular response to molecule of bacterial origin	16175	16481	GO:00022….
query_1	TRUE	0.0000000	128	912	40	0.0438596	0.3125000	GO:0042129	GO:BP	regulation of T cell proliferation	16175	9983	GO:00420….
query_1	TRUE	0.0000000	686	912	100	0.1096491	0.1457726	GO:0008284	GO:BP	positive regulation of cell population proliferation	16175	3151	GO:00082….
query_1	TRUE	0.0000000	1018	912	129	0.1414474	0.1267191	GO:2000026	GO:BP	regulation of multicellular organismal development	16175	25389	GO:00072….
query_1	TRUE	0.0000000	172	912	45	0.0493421	0.2616279	GO:0071216	GO:BP	cellular response to biotic stimulus	16175	16478	GO:00096….
query_1	TRUE	0.0000000	158	912	43	0.0471491	0.2721519	GO:0002285	GO:BP	lymphocyte activation involved in immune response	16175	817	GO:00023….
query_1	TRUE	0.0000000	10121	912	691	0.7576754	0.0682739	GO:0050789	GO:BP	regulation of biological process	16175	13258	GO:00081….
query_1	TRUE	0.0000000	106	912	35	0.0383772	0.3301887	GO:0051250	GO:BP	negative regulation of lymphocyte activation	16175	13597	GO:00026….
query_1	TRUE	0.0000000	77	912	30	0.0328947	0.3896104	GO:0042102	GO:BP	positive regulation of T cell proliferation	16175	9967	GO:00420….
query_1	TRUE	0.0000000	154	912	42	0.0460526	0.2727273	GO:0002819	GO:BP	regulation of adaptive immune response	16175	1329	GO:00022….
query_1	TRUE	0.0000000	224	912	51	0.0559211	0.2276786	GO:0006959	GO:BP	humoral immune response	16175	2590	GO:0006955
query_1	TRUE	0.0000000	185	912	46	0.0504386	0.2486486	GO:0006909	GO:BP	phagocytosis	16175	2559	GO:0006897
query_1	TRUE	0.0000000	90	912	32	0.0350877	0.3555556	GO:0032609	GO:BP	type II interferon production	16175	7657	GO:0001816
query_1	TRUE	0.0000000	90	912	32	0.0350877	0.3555556	GO:0032649	GO:BP	regulation of type II interferon production	16175	7696	GO:00018….
query_1	TRUE	0.0000000	203	912	48	0.0526316	0.2364532	GO:0002237	GO:BP	response to molecule of bacterial origin	16175	770	GO:00096….
query_1	TRUE	0.0000000	91	912	32	0.0350877	0.3516484	GO:0050864	GO:BP	regulation of B cell activation	16175	13312	GO:00421….
query_1	TRUE	0.0000000	91	912	32	0.0350877	0.3516484	GO:0031341	GO:BP	regulation of cell killing	16175	7132	GO:00019….
query_1	TRUE	0.0000000	2450	912	234	0.2565789	0.0955102	GO:0035556	GO:BP	intracellular signal transduction	16175	9090	GO:0007165
query_1	TRUE	0.0000000	92	912	32	0.0350877	0.3478261	GO:0032612	GO:BP	interleukin-1 production	16175	7660	GO:0001816
query_1	TRUE	0.0000000	92	912	32	0.0350877	0.3478261	GO:0032652	GO:BP	regulation of interleukin-1 production	16175	7699	GO:00018….
query_1	TRUE	0.0000000	81	912	30	0.0328947	0.3703704	GO:0032651	GO:BP	regulation of interleukin-1 beta production	16175	7698	GO:00326….
query_1	TRUE	0.0000000	81	912	30	0.0328947	0.3703704	GO:0032611	GO:BP	interleukin-1 beta production	16175	7659	GO:0032612
query_1	TRUE	0.0000000	50	912	24	0.0263158	0.4800000	GO:0006968	GO:BP	cellular defense response	16175	2596	GO:0006952
query_1	TRUE	0.0000000	50	912	24	0.0263158	0.4800000	GO:0050854	GO:BP	regulation of antigen receptor-mediated signaling pathway	16175	13302	GO:00099….
query_1	TRUE	0.0000000	1297	912	148	0.1622807	0.1141095	GO:0009967	GO:BP	positive regulation of signal transduction	16175	3805	GO:00071….
query_1	TRUE	0.0000000	2551	912	240	0.2631579	0.0940808	GO:0042221	GO:BP	response to chemical	16175	10049	GO:0050896
query_1	TRUE	0.0000000	9721	912	666	0.7302632	0.0685115	GO:0050794	GO:BP	regulation of cellular process	16175	13262	GO:00099….
query_1	TRUE	0.0000000	571	912	86	0.0942982	0.1506130	GO:0060284	GO:BP	regulation of cell development	16175	14500	GO:00455….
query_1	TRUE	0.0000000	936	912	118	0.1293860	0.1260684	GO:1902533	GO:BP	positive regulation of intracellular signal transduction	16175	22342	GO:00099….
query_1	TRUE	0.0000000	10482	912	704	0.7719298	0.0671628	GO:0065007	GO:BP	biological regulation	16175	15890	GO:0008150
query_1	TRUE	0.0000000	263	912	54	0.0592105	0.2053232	GO:0002218	GO:BP	activation of innate immune response	16175	753	GO:00022….
query_1	TRUE	0.0000000	116	912	35	0.0383772	0.3017241	GO:0032635	GO:BP	interleukin-6 production	16175	7682	GO:0001816
query_1	TRUE	0.0000000	116	912	35	0.0383772	0.3017241	GO:0032675	GO:BP	regulation of interleukin-6 production	16175	7721	GO:00018….
query_1	TRUE	0.0000000	152	912	40	0.0438596	0.2631579	GO:0045619	GO:BP	regulation of lymphocyte differentiation	16175	11470	GO:00300….
query_1	TRUE	0.0000000	186	912	44	0.0482456	0.2365591	GO:0097529	GO:BP	myeloid leukocyte migration	16175	18689	GO:0050900
query_1	TRUE	0.0000000	228	912	49	0.0537281	0.2149123	GO:0001818	GO:BP	negative regulation of cytokine production	16175	475	GO:00018….
query_1	TRUE	0.0000000	1876	912	189	0.2072368	0.1007463	GO:0048468	GO:BP	cell development	16175	12769	GO:00301….
query_1	TRUE	0.0000000	142	912	38	0.0416667	0.2676056	GO:0071222	GO:BP	cellular response to lipopolysaccharide	16175	16484	GO:00324….
query_1	TRUE	0.0000000	78	912	28	0.0307018	0.3589744	GO:0001910	GO:BP	regulation of leukocyte mediated cytotoxicity	16175	527	GO:00019….
query_1	TRUE	0.0000000	1205	912	137	0.1502193	0.1136929	GO:0016477	GO:BP	cell migration	16175	5229	GO:0048870
query_1	TRUE	0.0000000	1424	912	154	0.1688596	0.1081461	GO:0010647	GO:BP	positive regulation of cell communication	16175	4293	GO:00071….
query_1	TRUE	0.0000000	243	912	50	0.0548246	0.2057613	GO:0002758	GO:BP	innate immune response-activating signaling pathway	16175	1269	GO:00022….
query_1	TRUE	0.0000000	1427	912	154	0.1688596	0.1079187	GO:0023056	GO:BP	positive regulation of signaling	16175	6641	GO:00230….
query_1	TRUE	0.0000000	1647	912	170	0.1864035	0.1032180	GO:1902531	GO:BP	regulation of intracellular signal transduction	16175	22340	GO:00099….
query_1	TRUE	0.0000000	530	912	79	0.0866228	0.1490566	GO:0043408	GO:BP	regulation of MAPK cascade	16175	10676	GO:00001….
query_1	TRUE	0.0000000	149	912	38	0.0416667	0.2550336	GO:0050777	GO:BP	negative regulation of immune response	16175	13251	GO:00026….
query_1	TRUE	0.0000000	165	912	40	0.0438596	0.2424242	GO:0002573	GO:BP	myeloid leukocyte differentiation	16175	1094	GO:00025….
query_1	TRUE	0.0000000	107	912	32	0.0350877	0.2990654	GO:0034341	GO:BP	response to type II interferon	16175	8579	GO:00340….
query_1	TRUE	0.0000000	150	912	38	0.0416667	0.2533333	GO:0002440	GO:BP	production of molecular mediator of immune response	16175	963	GO:00023….
query_1	TRUE	0.0000000	76	912	27	0.0296053	0.3552632	GO:0042100	GO:BP	B cell proliferation	16175	9966	GO:00421….
query_1	TRUE	0.0000000	102	912	31	0.0339912	0.3039216	GO:0072676	GO:BP	lymphocyte migration	16175	17494	GO:0071674
query_1	TRUE	0.0000000	123	912	34	0.0372807	0.2764228	GO:0002700	GO:BP	regulation of production of molecular mediator of immune response	16175	1218	GO:00024….
query_1	TRUE	0.0000000	60	912	24	0.0263158	0.4000000	GO:0032729	GO:BP	positive regulation of type II interferon production	16175	7774	GO:00018….
query_1	TRUE	0.0000000	84	912	28	0.0307018	0.3333333	GO:0046634	GO:BP	regulation of alpha-beta T cell activation	16175	12271	GO:00466….
query_1	TRUE	0.0000000	139	912	36	0.0394737	0.2589928	GO:0002822	GO:BP	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	16175	1332	GO:00024….
query_1	TRUE	0.0000000	187	912	42	0.0460526	0.2245989	GO:0032496	GO:BP	response to lipopolysaccharide	16175	7607	GO:00022….
query_1	TRUE	0.0000000	85	912	28	0.0307018	0.3294118	GO:0046632	GO:BP	alpha-beta T cell differentiation	16175	12269	GO:00302….
query_1	TRUE	0.0000000	85	912	28	0.0307018	0.3294118	GO:0071346	GO:BP	cellular response to type II interferon	16175	16598	GO:00343….
query_1	TRUE	0.0000000	56	912	23	0.0252193	0.4107143	GO:0043299	GO:BP	leukocyte degranulation	16175	10607	GO:00022….
query_1	TRUE	0.0000000	56	912	23	0.0252193	0.4107143	GO:0032731	GO:BP	positive regulation of interleukin-1 beta production	16175	7776	GO:00326….
query_1	TRUE	0.0000000	133	912	35	0.0383772	0.2631579	GO:1903555	GO:BP	regulation of tumor necrosis factor superfamily cytokine production	16175	23102	GO:00018….
query_1	TRUE	0.0000000	133	912	35	0.0383772	0.2631579	GO:0071706	GO:BP	tumor necrosis factor superfamily cytokine production	16175	16870	GO:0001816
query_1	TRUE	0.0000000	62	912	24	0.0263158	0.3870968	GO:0048002	GO:BP	antigen processing and presentation of peptide antigen	16175	12460	GO:0019882
query_1	TRUE	0.0000000	80	912	27	0.0296053	0.3375000	GO:0002698	GO:BP	negative regulation of immune effector process	16175	1216	GO:00022….
query_1	TRUE	0.0000000	595	912	83	0.0910088	0.1394958	GO:0000165	GO:BP	MAPK cascade	16175	55	GO:0141124
query_1	TRUE	0.0000000	47	912	21	0.0230263	0.4468085	GO:0030888	GO:BP	regulation of B cell proliferation	16175	6953	GO:00421….
query_1	TRUE	0.0000000	63	912	24	0.0263158	0.3809524	GO:0032732	GO:BP	positive regulation of interleukin-1 production	16175	7777	GO:00018….
query_1	TRUE	0.0000000	136	912	35	0.0383772	0.2573529	GO:0002706	GO:BP	regulation of lymphocyte mediated immunity	16175	1224	GO:00024….
query_1	TRUE	0.0000000	376	912	62	0.0679825	0.1648936	GO:0043410	GO:BP	positive regulation of MAPK cascade	16175	10678	GO:00001….
query_1	TRUE	0.0000000	227	912	46	0.0504386	0.2026432	GO:0002221	GO:BP	pattern recognition receptor signaling pathway	16175	755	GO:0002758
query_1	TRUE	0.0000000	2543	912	229	0.2510965	0.0900511	GO:0009966	GO:BP	regulation of signal transduction	16175	3804	GO:00071….
query_1	TRUE	0.0000000	110	912	31	0.0339912	0.2818182	GO:0071621	GO:BP	granulocyte chemotaxis	16175	16801	GO:00305….
query_1	TRUE	0.0000000	91	912	28	0.0307018	0.3076923	GO:0030593	GO:BP	neutrophil chemotaxis	16175	6860	GO:00716….
query_1	TRUE	0.0000000	40	912	19	0.0208333	0.4750000	GO:0031295	GO:BP	T cell costimulation	16175	7117	GO:00312….
query_1	TRUE	0.0000000	127	912	33	0.0361842	0.2598425	GO:0097530	GO:BP	granulocyte migration	16175	18690	GO:0097529
query_1	TRUE	0.0000000	128	912	33	0.0361842	0.2578125	GO:0032680	GO:BP	regulation of tumor necrosis factor production	16175	7726	GO:00326….
query_1	TRUE	0.0000000	128	912	33	0.0361842	0.2578125	GO:0032640	GO:BP	tumor necrosis factor production	16175	7687	GO:0071706
query_1	TRUE	0.0000000	100	912	29	0.0317982	0.2900000	GO:1903038	GO:BP	negative regulation of leukocyte cell-cell adhesion	16175	22718	GO:00071….
query_1	TRUE	0.0000000	100	912	29	0.0317982	0.2900000	GO:0002286	GO:BP	T cell activation involved in immune response	16175	818	GO:00022….
query_1	TRUE	0.0000000	129	912	33	0.0361842	0.2558140	GO:0045580	GO:BP	regulation of T cell differentiation	16175	11431	GO:00302….
query_1	TRUE	0.0000000	1005	912	115	0.1260965	0.1144279	GO:0040011	GO:BP	locomotion	16175	9899	GO:0008150
query_1	TRUE	0.0000000	81	912	26	0.0285088	0.3209877	GO:0050764	GO:BP	regulation of phagocytosis	16175	13238	GO:00069….
query_1	TRUE	0.0000000	63	912	23	0.0252193	0.3650794	GO:0002275	GO:BP	myeloid cell activation involved in immune response	16175	807	GO:00022….
query_1	TRUE	0.0000000	334	912	56	0.0614035	0.1676647	GO:0009615	GO:BP	response to virus	16175	3541	GO:0051707
query_1	TRUE	0.0000000	42	912	19	0.0208333	0.4523810	GO:0031294	GO:BP	lymphocyte costimulation	16175	7116	GO:00023….
query_1	TRUE	0.0000000	89	912	27	0.0296053	0.3033708	GO:0050868	GO:BP	negative regulation of T cell activation	16175	13316	GO:00421….
query_1	TRUE	0.0000000	172	912	38	0.0416667	0.2209302	GO:0002685	GO:BP	regulation of leukocyte migration	16175	1203	GO:00026….
query_1	TRUE	0.0000000	319	912	54	0.0592105	0.1692790	GO:0032102	GO:BP	negative regulation of response to external stimulus	16175	7366	GO:00096….
query_1	TRUE	0.0000000	25	912	15	0.0164474	0.6000000	GO:0036336	GO:BP	dendritic cell migration	16175	9571	GO:0071674
query_1	TRUE	0.0000000	98	912	28	0.0307018	0.2857143	GO:0002456	GO:BP	T cell mediated immunity	16175	979	GO:00024….
query_1	TRUE	0.0000000	106	912	29	0.0317982	0.2735849	GO:1990266	GO:BP	neutrophil migration	16175	25128	GO:0097530
query_1	TRUE	0.0000000	39	912	18	0.0197368	0.4615385	GO:0019884	GO:BP	antigen processing and presentation of exogenous antigen	16175	6062	GO:0019882
query_1	TRUE	0.0000000	1373	912	141	0.1546053	0.1026948	GO:0048870	GO:BP	cell motility	16175	13113	GO:0009987
query_1	TRUE	0.0000000	124	912	31	0.0339912	0.2500000	GO:0050729	GO:BP	positive regulation of inflammatory response	16175	13228	GO:00069….
query_1	TRUE	0.0000000	88	912	26	0.0285088	0.2954545	GO:0035710	GO:BP	CD4-positive, alpha-beta T cell activation	16175	9184	GO:0046631
query_1	TRUE	0.0000000	148	912	34	0.0372807	0.2297297	GO:0022408	GO:BP	negative regulation of cell-cell adhesion	16175	6599	GO:00071….
query_1	TRUE	0.0000000	63	912	22	0.0241228	0.3492063	GO:0031343	GO:BP	positive regulation of cell killing	16175	7134	GO:00019….
query_1	TRUE	0.0000000	46	912	19	0.0208333	0.4130435	GO:0002704	GO:BP	negative regulation of leukocyte mediated immunity	16175	1222	GO:00024….
query_1	TRUE	0.0000000	2816	912	240	0.2631579	0.0852273	GO:0010646	GO:BP	regulation of cell communication	16175	4292	GO:00071….
query_1	TRUE	0.0000000	2808	912	239	0.2620614	0.0851140	GO:0023051	GO:BP	regulation of signaling	16175	6639	GO:00230….
query_1	TRUE	0.0000000	48	912	19	0.0208333	0.3958333	GO:0032623	GO:BP	interleukin-2 production	16175	7670	GO:0001816
query_1	TRUE	0.0000000	48	912	19	0.0208333	0.3958333	GO:0032663	GO:BP	regulation of interleukin-2 production	16175	7709	GO:00018….
query_1	TRUE	0.0000000	79	912	24	0.0263158	0.3037975	GO:0002367	GO:BP	cytokine production involved in immune response	16175	899	GO:00018….
query_1	TRUE	0.0000000	79	912	24	0.0263158	0.3037975	GO:0002718	GO:BP	regulation of cytokine production involved in immune response	16175	1236	GO:00018….
query_1	TRUE	0.0000000	291	912	49	0.0537281	0.1683849	GO:0030099	GO:BP	myeloid cell differentiation	16175	6677	GO:00300….
query_1	TRUE	0.0000000	29	912	15	0.0164474	0.5172414	GO:0097028	GO:BP	dendritic cell differentiation	16175	18451	GO:1903131
query_1	TRUE	0.0000000	29	912	15	0.0164474	0.5172414	GO:0002495	GO:BP	antigen processing and presentation of peptide antigen via MHC class II	16175	1018	GO:00025….
query_1	TRUE	0.0000000	1790	912	168	0.1842105	0.0938547	GO:0050793	GO:BP	regulation of developmental process	16175	13261	GO:00325….
query_1	TRUE	0.0000000	68	912	22	0.0241228	0.3235294	GO:0070098	GO:BP	chemokine-mediated signaling pathway	16175	15910	GO:00071….
query_1	TRUE	0.0000000	50	912	19	0.0208333	0.3800000	GO:0032655	GO:BP	regulation of interleukin-12 production	16175	7702	GO:00018….
query_1	TRUE	0.0000000	50	912	19	0.0208333	0.3800000	GO:0032615	GO:BP	interleukin-12 production	16175	7663	GO:0001816
query_1	TRUE	0.0000000	110	912	28	0.0307018	0.2545455	GO:0002705	GO:BP	positive regulation of leukocyte mediated immunity	16175	1223	GO:00024….
query_1	TRUE	0.0000000	1404	912	140	0.1535088	0.0997151	GO:0012501	GO:BP	programmed cell death	16175	4572	GO:0008219
query_1	TRUE	0.0000000	56	912	20	0.0219298	0.3571429	GO:0006956	GO:BP	complement activation	16175	2587	GO:00022….
query_1	TRUE	0.0000000	82	912	24	0.0263158	0.2926829	GO:0032677	GO:BP	regulation of interleukin-8 production	16175	7723	GO:00018….
query_1	TRUE	0.0000000	82	912	24	0.0263158	0.2926829	GO:0032637	GO:BP	interleukin-8 production	16175	7684	GO:0001816
query_1	TRUE	0.0000000	1409	912	140	0.1535088	0.0993612	GO:0008219	GO:BP	cell death	16175	3146	GO:0009987
query_1	TRUE	0.0000000	63	912	21	0.0230263	0.3333333	GO:0070664	GO:BP	negative regulation of leukocyte proliferation	16175	16245	GO:00082….
query_1	TRUE	0.0000000	76	912	23	0.0252193	0.3026316	GO:1990869	GO:BP	cellular response to chemokine	16175	25324	GO:00713….
query_1	TRUE	0.0000000	76	912	23	0.0252193	0.3026316	GO:1990868	GO:BP	response to chemokine	16175	25323	GO:0034097
query_1	TRUE	0.0000000	22	912	13	0.0142544	0.5909091	GO:0002407	GO:BP	dendritic cell chemotaxis	16175	931	GO:00305….
query_1	TRUE	0.0000000	197	912	38	0.0416667	0.1928934	GO:0031348	GO:BP	negative regulation of defense response	16175	7139	GO:00069….
query_1	TRUE	0.0000000	31	912	15	0.0164474	0.4838710	GO:0002504	GO:BP	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	16175	1027	GO:0019882
query_1	TRUE	0.0000000	114	912	28	0.0307018	0.2456140	GO:0071675	GO:BP	regulation of mononuclear cell migration	16175	16848	GO:00026….
query_1	TRUE	0.0000000	255	912	44	0.0482456	0.1725490	GO:0070371	GO:BP	ERK1 and ERK2 cascade	16175	16082	GO:0000165
query_1	TRUE	0.0000000	78	912	23	0.0252193	0.2948718	GO:0032755	GO:BP	positive regulation of interleukin-6 production	16175	7799	GO:00018….
query_1	TRUE	0.0000000	533	912	70	0.0767544	0.1313321	GO:0006897	GO:BP	endocytosis	16175	2551	GO:00161….
query_1	TRUE	0.0000000	72	912	22	0.0241228	0.3055556	GO:0002444	GO:BP	myeloid leukocyte mediated immunity	16175	967	GO:0002443
query_1	TRUE	0.0000000	72	912	22	0.0241228	0.3055556	GO:0043367	GO:BP	CD4-positive, alpha-beta T cell differentiation	16175	10644	GO:00357….
query_1	TRUE	0.0000000	774	912	90	0.0986842	0.1162791	GO:0007186	GO:BP	G protein-coupled receptor signaling pathway	16175	2744	GO:0007165
query_1	TRUE	0.0000000	1347	912	134	0.1469298	0.0994803	GO:0006915	GO:BP	apoptotic process	16175	2564	GO:0012501
query_1	TRUE	0.0000000	66	912	21	0.0230263	0.3181818	GO:0002292	GO:BP	T cell differentiation involved in immune response	16175	824	GO:00022….
query_1	TRUE	0.0000000	37	912	16	0.0175439	0.4324324	GO:0045058	GO:BP	T cell selection	16175	11256	GO:00023….
query_1	TRUE	0.0000000	166	912	34	0.0372807	0.2048193	GO:0019722	GO:BP	calcium-mediated signaling	16175	6018	GO:0141124
query_1	TRUE	0.0000000	1123	912	117	0.1282895	0.1041852	GO:0045595	GO:BP	regulation of cell differentiation	16175	11446	GO:00301….
query_1	TRUE	0.0000000	60	912	20	0.0219298	0.3333333	GO:0002228	GO:BP	natural killer cell mediated immunity	16175	761	GO:00024….
query_1	TRUE	0.0000000	80	912	23	0.0252193	0.2875000	GO:0002709	GO:BP	regulation of T cell mediated immunity	16175	1227	GO:00024….
query_1	TRUE	0.0000000	117	912	28	0.0307018	0.2393162	GO:0002687	GO:BP	positive regulation of leukocyte migration	16175	1205	GO:00026….
query_1	TRUE	0.0000000	67	912	21	0.0230263	0.3134328	GO:0002548	GO:BP	monocyte chemotaxis	16175	1069	GO:00305….
query_1	TRUE	0.0000000	33	912	15	0.0164474	0.4545455	GO:0002478	GO:BP	antigen processing and presentation of exogenous peptide antigen	16175	1001	GO:00198….
query_1	TRUE	0.0000000	33	912	15	0.0164474	0.4545455	GO:0045730	GO:BP	respiratory burst	16175	11572	GO:0008152
query_1	TRUE	0.0000000	62	912	20	0.0219298	0.3225806	GO:0002293	GO:BP	alpha-beta T cell differentiation involved in immune response	16175	825	GO:00022….
query_1	TRUE	0.0000000	62	912	20	0.0219298	0.3225806	GO:0002287	GO:BP	alpha-beta T cell activation involved in immune response	16175	819	GO:00022….
query_1	TRUE	0.0000000	1616	912	152	0.1666667	0.0940594	GO:0070887	GO:BP	cellular response to chemical stimulus	16175	16358	GO:00422….
query_1	TRUE	0.0000000	105	912	26	0.0285088	0.2476190	GO:0070555	GO:BP	response to interleukin-1	16175	16175	GO:0034097
query_1	TRUE	0.0000000	228	912	40	0.0438596	0.1754386	GO:0051607	GO:BP	defense response to virus	16175	13823	GO:00096….
query_1	TRUE	0.0000000	57	912	19	0.0208333	0.3333333	GO:0072678	GO:BP	T cell migration	16175	17496	GO:0072676
query_1	TRUE	0.0000000	57	912	19	0.0208333	0.3333333	GO:0050672	GO:BP	negative regulation of lymphocyte proliferation	16175	13206	GO:00329….
query_1	TRUE	0.0000000	57	912	19	0.0208333	0.3333333	GO:0001912	GO:BP	positive regulation of leukocyte mediated cytotoxicity	16175	529	GO:00019….
query_1	TRUE	0.0000000	84	912	23	0.0252193	0.2738095	GO:1903557	GO:BP	positive regulation of tumor necrosis factor superfamily cytokine production	16175	23104	GO:00018….
query_1	TRUE	0.0000000	139	912	30	0.0328947	0.2158273	GO:1902107	GO:BP	positive regulation of leukocyte differentiation	16175	22021	GO:00025….
query_1	TRUE	0.0000000	139	912	30	0.0328947	0.2158273	GO:1903708	GO:BP	positive regulation of hemopoiesis	16175	23222	GO:00026….
query_1	TRUE	0.0000000	17	912	11	0.0120614	0.6470588	GO:0050855	GO:BP	regulation of B cell receptor signaling pathway	16175	13303	GO:00508….
query_1	TRUE	0.0000000	58	912	19	0.0208333	0.3275862	GO:0032945	GO:BP	negative regulation of mononuclear cell proliferation	16175	7930	GO:00329….
query_1	TRUE	0.0000000	30	912	14	0.0153509	0.4666667	GO:0042088	GO:BP	T-helper 1 type immune response	16175	9962	GO:0002460
query_1	TRUE	0.0000000	214	912	38	0.0416667	0.1775701	GO:0018108	GO:BP	peptidyl-tyrosine phosphorylation	16175	5327	GO:00064….
query_1	TRUE	0.0000000	59	912	19	0.0208333	0.3220339	GO:0002224	GO:BP	toll-like receptor signaling pathway	16175	758	GO:0002221
query_1	TRUE	0.0000000	59	912	19	0.0208333	0.3220339	GO:0042267	GO:BP	natural killer cell mediated cytotoxicity	16175	10065	GO:00019….
query_1	TRUE	0.0000000	59	912	19	0.0208333	0.3220339	GO:0050766	GO:BP	positive regulation of phagocytosis	16175	13240	GO:00069….
query_1	TRUE	0.0000000	59	912	19	0.0208333	0.3220339	GO:0048247	GO:BP	lymphocyte chemotaxis	16175	12605	GO:00305….
query_1	TRUE	0.0000000	244	912	41	0.0449561	0.1680328	GO:0042742	GO:BP	defense response to bacterium	16175	10335	GO:00096….
query_1	TRUE	0.0000000	215	912	38	0.0416667	0.1767442	GO:0018212	GO:BP	peptidyl-tyrosine modification	16175	5371	GO:0018193
query_1	TRUE	0.0000000	2076	912	182	0.1995614	0.0876686	GO:0010557	GO:BP	positive regulation of macromolecule biosynthetic process	16175	4210	GO:00090….
query_1	TRUE	0.0000000	80	912	22	0.0241228	0.2750000	GO:0032760	GO:BP	positive regulation of tumor necrosis factor production	16175	7804	GO:00326….
query_1	TRUE	0.0000000	95	912	24	0.0263158	0.2526316	GO:0002702	GO:BP	positive regulation of production of molecular mediator of immune response	16175	1220	GO:00024….
query_1	TRUE	0.0000000	18	912	11	0.0120614	0.6111111	GO:0002577	GO:BP	regulation of antigen processing and presentation	16175	1098	GO:00026….
query_1	TRUE	0.0000000	54	912	18	0.0197368	0.3333333	GO:0046637	GO:BP	regulation of alpha-beta T cell differentiation	16175	12274	GO:00455….
query_1	TRUE	0.0000000	1098	912	112	0.1228070	0.1020036	GO:0043067	GO:BP	regulation of programmed cell death	16175	10513	GO:00125….
query_1	TRUE	0.0000000	104	912	25	0.0274123	0.2403846	GO:0002688	GO:BP	regulation of leukocyte chemotaxis	16175	1206	GO:00026….
query_1	TRUE	0.0000000	61	912	19	0.0208333	0.3114754	GO:0002294	GO:BP	CD4-positive, alpha-beta T cell differentiation involved in immune response	16175	826	GO:00022….
query_1	TRUE	0.0000000	239	912	40	0.0438596	0.1673640	GO:0070372	GO:BP	regulation of ERK1 and ERK2 cascade	16175	16083	GO:00434….
query_1	TRUE	0.0000000	75	912	21	0.0230263	0.2800000	GO:1902106	GO:BP	negative regulation of leukocyte differentiation	16175	22020	GO:00025….
query_1	TRUE	0.0000000	175	912	33	0.0361842	0.1885714	GO:0070374	GO:BP	positive regulation of ERK1 and ERK2 cascade	16175	16085	GO:00434….
query_1	TRUE	0.0000000	232	912	39	0.0427632	0.1681034	GO:0007162	GO:BP	negative regulation of cell adhesion	16175	2726	GO:00071….
query_1	TRUE	0.0000000	979	912	102	0.1118421	0.1041879	GO:1901700	GO:BP	response to oxygen-containing compound	16175	21653	GO:0042221
query_1	TRUE	0.0000000	9	912	8	0.0087719	0.8888889	GO:0043301	GO:BP	negative regulation of leukocyte degranulation	16175	10609	GO:00026….
query_1	TRUE	0.0000000	77	912	21	0.0230263	0.2727273	GO:1903707	GO:BP	negative regulation of hemopoiesis	16175	23221	GO:00026….
query_1	TRUE	0.0000000	124	912	27	0.0296053	0.2177419	GO:0045807	GO:BP	positive regulation of endocytosis	16175	11631	GO:00068….
query_1	TRUE	0.0000000	116	912	26	0.0285088	0.2241379	GO:0050921	GO:BP	positive regulation of chemotaxis	16175	13363	GO:00069….
query_1	TRUE	0.0000000	57	912	18	0.0197368	0.3157895	GO:2000514	GO:BP	regulation of CD4-positive, alpha-beta T cell activation	16175	25817	GO:00357….
query_1	TRUE	0.0000000	1063	912	108	0.1184211	0.1015992	GO:0042981	GO:BP	regulation of apoptotic process	16175	10465	GO:00069….
query_1	TRUE	0.0000000	653	912	76	0.0833333	0.1163859	GO:0051050	GO:BP	positive regulation of transport	16175	13460	GO:00068….
query_1	TRUE	0.0000000	45	912	16	0.0175439	0.3555556	GO:0032613	GO:BP	interleukin-10 production	16175	7661	GO:0001816
query_1	TRUE	0.0000000	45	912	16	0.0175439	0.3555556	GO:0032653	GO:BP	regulation of interleukin-10 production	16175	7700	GO:00018….
query_1	TRUE	0.0000000	4231	912	318	0.3486842	0.0751595	GO:0048856	GO:BP	anatomical structure development	16175	13100	GO:0032502
query_1	TRUE	0.0000000	24	912	12	0.0131579	0.5000000	GO:0036037	GO:BP	CD8-positive, alpha-beta T cell activation	16175	9403	GO:0046631
query_1	TRUE	0.0000000	34	912	14	0.0153509	0.4117647	GO:0043300	GO:BP	regulation of leukocyte degranulation	16175	10608	GO:00026….
query_1	TRUE	0.0000000	79	912	21	0.0230263	0.2658228	GO:0042116	GO:BP	macrophage activation	16175	9972	GO:0002274
query_1	TRUE	0.0000000	72	912	20	0.0219298	0.2777778	GO:0032602	GO:BP	chemokine production	16175	7650	GO:0001816
query_1	TRUE	0.0000000	72	912	20	0.0219298	0.2777778	GO:0032642	GO:BP	regulation of chemokine production	16175	7689	GO:00018….
query_1	TRUE	0.0000000	7	912	7	0.0076754	1.0000000	GO:0002887	GO:BP	negative regulation of myeloid leukocyte mediated immunity	16175	1397	GO:00024….
query_1	TRUE	0.0000000	479	912	61	0.0668860	0.1273486	GO:0040017	GO:BP	positive regulation of locomotion	16175	9905	GO:00400….
query_1	TRUE	0.0000000	181	912	33	0.0361842	0.1823204	GO:0050920	GO:BP	regulation of chemotaxis	16175	13362	GO:00069….
query_1	TRUE	0.0000000	59	912	18	0.0197368	0.3050847	GO:0042093	GO:BP	T-helper cell differentiation	16175	9964	GO:0002294
query_1	TRUE	0.0000000	2156	912	184	0.2017544	0.0853432	GO:0009891	GO:BP	positive regulation of biosynthetic process	16175	3751	GO:00090….
query_1	TRUE	0.0000000	35	912	14	0.0153509	0.4000000	GO:0050856	GO:BP	regulation of T cell receptor signaling pathway	16175	13304	GO:00508….
query_1	TRUE	0.0000000	1351	912	128	0.1403509	0.0947446	GO:0048585	GO:BP	negative regulation of response to stimulus	16175	12856	GO:00485….
query_1	TRUE	0.0000000	53	912	17	0.0186404	0.3207547	GO:0046635	GO:BP	positive regulation of alpha-beta T cell activation	16175	12272	GO:00466….
query_1	TRUE	0.0000000	25	912	12	0.0131579	0.4800000	GO:0002455	GO:BP	humoral immune response mediated by circulating immunoglobulin	16175	978	GO:00069….
query_1	TRUE	0.0000000	25	912	12	0.0131579	0.4800000	GO:0019886	GO:BP	antigen processing and presentation of exogenous peptide antigen via MHC class II	16175	6064	GO:00024….
query_1	TRUE	0.0000000	81	912	21	0.0230263	0.2592593	GO:0002690	GO:BP	positive regulation of leukocyte chemotaxis	16175	1208	GO:00026….
query_1	TRUE	0.0000000	283	912	43	0.0471491	0.1519435	GO:0010720	GO:BP	positive regulation of cell development	16175	4346	GO:00455….
query_1	TRUE	0.0000000	41	912	15	0.0164474	0.3658537	GO:0036230	GO:BP	granulocyte activation	16175	9504	GO:0002274
query_1	TRUE	0.0000000	2938	912	235	0.2576754	0.0799864	GO:0048869	GO:BP	cellular developmental process	16175	13112	GO:00099….
query_1	TRUE	0.0000000	2938	912	235	0.2576754	0.0799864	GO:0030154	GO:BP	cell differentiation	16175	6687	GO:0048869
query_1	TRUE	0.0000001	89	912	22	0.0241228	0.2471910	GO:0002761	GO:BP	regulation of myeloid leukocyte differentiation	16175	1272	GO:00025….
query_1	TRUE	0.0000001	89	912	22	0.0241228	0.2471910	GO:0071347	GO:BP	cellular response to interleukin-1	16175	16599	GO:00705….
query_1	TRUE	0.0000001	450	912	58	0.0635965	0.1288889	GO:0030335	GO:BP	positive regulation of cell migration	16175	6781	GO:00164….
query_1	TRUE	0.0000001	13	912	9	0.0098684	0.6923077	GO:0002503	GO:BP	peptide antigen assembly with MHC class II protein complex	16175	1026	GO:00023….
query_1	TRUE	0.0000001	13	912	9	0.0098684	0.6923077	GO:0002399	GO:BP	MHC class II protein complex assembly	16175	923	GO:0002396
query_1	TRUE	0.0000001	21	912	11	0.0120614	0.5238095	GO:0002507	GO:BP	tolerance induction	16175	1029	GO:00023….
query_1	TRUE	0.0000001	42	912	15	0.0164474	0.3571429	GO:0061756	GO:BP	leukocyte adhesion to vascular endothelial cell	16175	15650	GO:0007159
query_1	TRUE	0.0000001	31	912	13	0.0142544	0.4193548	GO:0043368	GO:BP	positive T cell selection	16175	10645	GO:0045058
query_1	TRUE	0.0000001	62	912	18	0.0197368	0.2903226	GO:0002532	GO:BP	production of molecular mediator involved in inflammatory response	16175	1054	GO:00069….
query_1	TRUE	0.0000001	92	912	22	0.0241228	0.2391304	GO:0002708	GO:BP	positive regulation of lymphocyte mediated immunity	16175	1226	GO:00024….
query_1	TRUE	0.0000001	791	912	85	0.0932018	0.1074589	GO:1901701	GO:BP	cellular response to oxygen-containing compound	16175	21654	GO:00708….
query_1	TRUE	0.0000001	470	912	59	0.0646930	0.1255319	GO:2000147	GO:BP	positive regulation of cell motility	16175	25495	GO:00400….
query_1	TRUE	0.0000001	77	912	20	0.0219298	0.2597403	GO:0071677	GO:BP	positive regulation of mononuclear cell migration	16175	16850	GO:00026….
query_1	TRUE	0.0000001	56	912	17	0.0186404	0.3035714	GO:0002720	GO:BP	positive regulation of cytokine production involved in immune response	16175	1238	GO:00018….
query_1	TRUE	0.0000001	221	912	36	0.0394737	0.1628959	GO:0030100	GO:BP	regulation of endocytosis	16175	6678	GO:00068….
query_1	TRUE	0.0000001	44	912	15	0.0164474	0.3409091	GO:0006911	GO:BP	phagocytosis, engulfment	16175	2561	GO:00069….
query_1	TRUE	0.0000001	44	912	15	0.0164474	0.3409091	GO:0002437	GO:BP	inflammatory response to antigenic stimulus	16175	960	GO:00069….
query_1	TRUE	0.0000001	44	912	15	0.0164474	0.3409091	GO:0043370	GO:BP	regulation of CD4-positive, alpha-beta T cell differentiation	16175	10647	GO:00433….
query_1	TRUE	0.0000001	44	912	15	0.0164474	0.3409091	GO:0001776	GO:BP	leukocyte homeostasis	16175	441	GO:00023….
query_1	TRUE	0.0000001	14	912	9	0.0098684	0.6428571	GO:0046629	GO:BP	gamma-delta T cell activation	16175	12266	GO:0042110
query_1	TRUE	0.0000002	1538	912	139	0.1524123	0.0903771	GO:0065009	GO:BP	regulation of molecular function	16175	15892	GO:0065007
query_1	TRUE	0.0000002	33	912	13	0.0142544	0.3939394	GO:0070269	GO:BP	pyroptotic inflammatory response	16175	16029	GO:0006954
query_1	TRUE	0.0000002	45	912	15	0.0164474	0.3333333	GO:0001913	GO:BP	T cell mediated cytotoxicity	16175	530	GO:00019….
query_1	TRUE	0.0000002	138	912	27	0.0296053	0.1956522	GO:1903900	GO:BP	regulation of viral life cycle	16175	23367	GO:00190….
query_1	TRUE	0.0000002	28	912	12	0.0131579	0.4285714	GO:0019883	GO:BP	antigen processing and presentation of endogenous antigen	16175	6061	GO:0019882
query_1	TRUE	0.0000002	96	912	22	0.0241228	0.2291667	GO:0002821	GO:BP	positive regulation of adaptive immune response	16175	1331	GO:00022….
query_1	TRUE	0.0000002	73	912	19	0.0208333	0.2602740	GO:0033627	GO:BP	cell adhesion mediated by integrin	16175	8328	GO:0007155
query_1	TRUE	0.0000002	73	912	19	0.0208333	0.2602740	GO:0071887	GO:BP	leukocyte apoptotic process	16175	16965	GO:0006915
query_1	TRUE	0.0000003	59	912	17	0.0186404	0.2881356	GO:0045123	GO:BP	cellular extravasation	16175	11289	GO:0050900
query_1	TRUE	0.0000003	40	912	14	0.0153509	0.3500000	GO:0002715	GO:BP	regulation of natural killer cell mediated immunity	16175	1233	GO:00022….
query_1	TRUE	0.0000003	19	912	10	0.0109649	0.5263158	GO:0001911	GO:BP	negative regulation of leukocyte mediated cytotoxicity	16175	528	GO:00019….
query_1	TRUE	0.0000003	19	912	10	0.0109649	0.5263158	GO:0002710	GO:BP	negative regulation of T cell mediated immunity	16175	1228	GO:00024….
query_1	TRUE	0.0000003	53	912	16	0.0175439	0.3018868	GO:0150076	GO:BP	neuroinflammatory response	16175	20128	GO:0006954
query_1	TRUE	0.0000003	324	912	45	0.0493421	0.1388889	GO:0006816	GO:BP	calcium ion transport	16175	2495	GO:0030001
query_1	TRUE	0.0000004	124	912	25	0.0274123	0.2016129	GO:0051092	GO:BP	positive regulation of NF-kappaB transcription factor activity	16175	13487	GO:0051091
query_1	TRUE	0.0000004	24	912	11	0.0120614	0.4583333	GO:0010818	GO:BP	T cell chemotaxis	16175	4430	GO:00482….
query_1	TRUE	0.0000004	170	912	30	0.0328947	0.1764706	GO:0010721	GO:BP	negative regulation of cell development	16175	4347	GO:00455….
query_1	TRUE	0.0000004	47	912	15	0.0164474	0.3191489	GO:0002534	GO:BP	cytokine production involved in inflammatory response	16175	1056	GO:00018….
query_1	TRUE	0.0000004	47	912	15	0.0164474	0.3191489	GO:1900015	GO:BP	regulation of cytokine production involved in inflammatory response	16175	20326	GO:00018….
query_1	TRUE	0.0000004	99	912	22	0.0241228	0.2222222	GO:0045621	GO:BP	positive regulation of lymphocyte differentiation	16175	11472	GO:00300….
query_1	TRUE	0.0000005	109	912	23	0.0252193	0.2110092	GO:0030183	GO:BP	B cell differentiation	16175	6700	GO:00300….
query_1	TRUE	0.0000006	62	912	17	0.0186404	0.2741935	GO:0032757	GO:BP	positive regulation of interleukin-8 production	16175	7801	GO:00018….
query_1	TRUE	0.0000006	20	912	10	0.0109649	0.5000000	GO:0006958	GO:BP	complement activation, classical pathway	16175	2589	GO:00024….
query_1	TRUE	0.0000006	55	912	16	0.0175439	0.2909091	GO:2000401	GO:BP	regulation of lymphocyte migration	16175	25716	GO:00716….
query_1	TRUE	0.0000006	770	912	81	0.0888158	0.1051948	GO:0048646	GO:BP	anatomical structure formation involved in morphogenesis	16175	12904	GO:00096….
query_1	TRUE	0.0000006	42	912	14	0.0153509	0.3333333	GO:0001914	GO:BP	regulation of T cell mediated cytotoxicity	16175	531	GO:00019….
query_1	TRUE	0.0000006	25	912	11	0.0120614	0.4400000	GO:0050858	GO:BP	negative regulation of antigen receptor-mediated signaling pathway	16175	13306	GO:00026….
query_1	TRUE	0.0000006	146	912	27	0.0296053	0.1849315	GO:0062207	GO:BP	regulation of pattern recognition receptor signaling pathway	16175	15863	GO:00022….
query_1	TRUE	0.0000007	102	912	22	0.0241228	0.2156863	GO:0002832	GO:BP	negative regulation of response to biotic stimulus	16175	1342	GO:00028….
query_1	TRUE	0.0000007	4413	912	321	0.3519737	0.0727396	GO:0048519	GO:BP	negative regulation of biological process	16175	12802	GO:00081….
query_1	TRUE	0.0000007	401	912	51	0.0559211	0.1271820	GO:0043068	GO:BP	positive regulation of programmed cell death	16175	10514	GO:00125….
query_1	TRUE	0.0000008	129	912	25	0.0274123	0.1937984	GO:0007204	GO:BP	positive regulation of cytosolic calcium ion concentration	16175	2759	GO:0065008
query_1	TRUE	0.0000009	280	912	40	0.0438596	0.1428571	GO:0007249	GO:BP	canonical NF-kappaB signal transduction	16175	2783	GO:0141124
query_1	TRUE	0.0000009	740	912	78	0.0855263	0.1054054	GO:0098657	GO:BP	import into cell	16175	18813	GO:0006810
query_1	TRUE	0.0000009	57	912	16	0.0175439	0.2807018	GO:2000106	GO:BP	regulation of leukocyte apoptotic process	16175	25457	GO:00429….
query_1	TRUE	0.0000010	26	912	11	0.0120614	0.4230769	GO:0032743	GO:BP	positive regulation of interleukin-2 production	16175	7787	GO:00018….
query_1	TRUE	0.0000011	2767	912	217	0.2379386	0.0784243	GO:0010604	GO:BP	positive regulation of macromolecule metabolic process	16175	4251	GO:00098….
query_1	TRUE	0.0000011	150	912	27	0.0296053	0.1800000	GO:0051897	GO:BP	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	16175	13981	GO:00434….
query_1	TRUE	0.0000012	32	912	12	0.0131579	0.3750000	GO:0009595	GO:BP	detection of biotic stimulus	16175	3526	GO:00096….
query_1	TRUE	0.0000012	38	912	13	0.0142544	0.3421053	GO:0002886	GO:BP	regulation of myeloid leukocyte mediated immunity	16175	1396	GO:00024….
query_1	TRUE	0.0000012	38	912	13	0.0142544	0.3421053	GO:0042269	GO:BP	regulation of natural killer cell mediated cytotoxicity	16175	10067	GO:00019….
query_1	TRUE	0.0000012	160	912	28	0.0307018	0.1750000	GO:0050792	GO:BP	regulation of viral process	16175	13260	GO:00160….
query_1	TRUE	0.0000012	123	912	24	0.0263158	0.1951220	GO:0019730	GO:BP	antimicrobial humoral response	16175	6021	GO:00069….
query_1	TRUE	0.0000012	409	912	51	0.0559211	0.1246944	GO:0060627	GO:BP	regulation of vesicle-mediated transport	16175	14803	GO:00161….
query_1	TRUE	0.0000013	89	912	20	0.0219298	0.2247191	GO:0002824	GO:BP	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	16175	1334	GO:00024….
query_1	TRUE	0.0000014	161	912	28	0.0307018	0.1739130	GO:0045637	GO:BP	regulation of myeloid cell differentiation	16175	11488	GO:00300….
query_1	TRUE	0.0000015	13	912	8	0.0087719	0.6153846	GO:0002468	GO:BP	dendritic cell antigen processing and presentation	16175	991	GO:0019882
query_1	TRUE	0.0000015	74	912	18	0.0197368	0.2432432	GO:1901222	GO:BP	regulation of non-canonical NF-kappaB signal transduction	16175	21316	GO:00380….
query_1	TRUE	0.0000015	90	912	20	0.0219298	0.2222222	GO:0048525	GO:BP	negative regulation of viral process	16175	12808	GO:00160….
query_1	TRUE	0.0000016	52	912	15	0.0164474	0.2884615	GO:0099024	GO:BP	plasma membrane invagination	16175	19012	GO:0010324
query_1	TRUE	0.0000016	22	912	10	0.0109649	0.4545455	GO:0031342	GO:BP	negative regulation of cell killing	16175	7133	GO:00019….
query_1	TRUE	0.0000017	39	912	13	0.0142544	0.3333333	GO:0002707	GO:BP	negative regulation of lymphocyte mediated immunity	16175	1225	GO:00024….
query_1	TRUE	0.0000017	39	912	13	0.0142544	0.3333333	GO:0031663	GO:BP	lipopolysaccharide-mediated signaling pathway	16175	7267	GO:00071….
query_1	TRUE	0.0000017	33	912	12	0.0131579	0.3636364	GO:0042119	GO:BP	neutrophil activation	16175	9975	GO:0036230
query_1	TRUE	0.0000020	781	912	80	0.0877193	0.1024328	GO:0030334	GO:BP	regulation of cell migration	16175	6780	GO:00164….
query_1	TRUE	0.0000023	28	912	11	0.0120614	0.3928571	GO:0050901	GO:BP	leukocyte tethering or rolling	16175	13343	GO:00451….
query_1	TRUE	0.0000023	175	912	29	0.0317982	0.1657143	GO:0050730	GO:BP	regulation of peptidyl-tyrosine phosphorylation	16175	13229	GO:00019….
query_1	TRUE	0.0000025	34	912	12	0.0131579	0.3529412	GO:0032735	GO:BP	positive regulation of interleukin-12 production	16175	7780	GO:00018….
query_1	TRUE	0.0000025	34	912	12	0.0131579	0.3529412	GO:0032715	GO:BP	negative regulation of interleukin-6 production	16175	7760	GO:00018….
query_1	TRUE	0.0000025	18	912	9	0.0098684	0.5000000	GO:0002396	GO:BP	MHC protein complex assembly	16175	920	GO:0065003
query_1	TRUE	0.0000025	18	912	9	0.0098684	0.5000000	GO:0002501	GO:BP	peptide antigen assembly with MHC protein complex	16175	1024	GO:00023….
query_1	TRUE	0.0000025	1253	912	114	0.1250000	0.0909816	GO:0051049	GO:BP	regulation of transport	16175	13459	GO:00068….
query_1	TRUE	0.0000026	119	912	23	0.0252193	0.1932773	GO:0050728	GO:BP	negative regulation of inflammatory response	16175	13227	GO:00069….
query_1	TRUE	0.0000026	54	912	15	0.0164474	0.2777778	GO:0034113	GO:BP	heterotypic cell-cell adhesion	16175	8421	GO:0098609
query_1	TRUE	0.0000026	23	912	10	0.0109649	0.4347826	GO:0050869	GO:BP	negative regulation of B cell activation	16175	13317	GO:00421….
query_1	TRUE	0.0000026	23	912	10	0.0109649	0.4347826	GO:1901623	GO:BP	regulation of lymphocyte chemotaxis	16175	21603	GO:00026….
query_1	TRUE	0.0000031	41	912	13	0.0142544	0.3170732	GO:0002820	GO:BP	negative regulation of adaptive immune response	16175	1330	GO:00022….
query_1	TRUE	0.0000031	41	912	13	0.0142544	0.3170732	GO:0045576	GO:BP	mast cell activation	16175	11427	GO:0002274
query_1	TRUE	0.0000032	520	912	59	0.0646930	0.1134615	GO:0033993	GO:BP	response to lipid	16175	8371	GO:0042221
query_1	TRUE	0.0000034	86	912	19	0.0208333	0.2209302	GO:0045582	GO:BP	positive regulation of T cell differentiation	16175	11433	GO:00302….
query_1	TRUE	0.0000034	3045	912	232	0.2543860	0.0761905	GO:0009893	GO:BP	positive regulation of metabolic process	16175	3753	GO:00081….
query_1	TRUE	0.0000039	131	912	24	0.0263158	0.1832061	GO:0050731	GO:BP	positive regulation of peptidyl-tyrosine phosphorylation	16175	13230	GO:00019….
query_1	TRUE	0.0000039	916	912	89	0.0975877	0.0971616	GO:0044093	GO:BP	positive regulation of molecular function	16175	10915	GO:0065009
query_1	TRUE	0.0000042	180	912	29	0.0317982	0.1611111	GO:0034612	GO:BP	response to tumor necrosis factor	16175	8690	GO:0034097
query_1	TRUE	0.0000043	56	912	15	0.0164474	0.2678571	GO:0032722	GO:BP	positive regulation of chemokine production	16175	7767	GO:00018….
query_1	TRUE	0.0000044	19	912	9	0.0098684	0.4736842	GO:0098543	GO:BP	detection of other organism	16175	18795	GO:00517….
query_1	TRUE	0.0000044	19	912	9	0.0098684	0.4736842	GO:0090023	GO:BP	positive regulation of neutrophil chemotaxis	16175	17957	GO:00305….
query_1	TRUE	0.0000046	161	912	27	0.0296053	0.1677019	GO:0045055	GO:BP	regulated exocytosis	16175	11253	GO:0006887
query_1	TRUE	0.0000049	30	912	11	0.0120614	0.3666667	GO:0002260	GO:BP	lymphocyte homeostasis	16175	792	GO:0001776
query_1	TRUE	0.0000049	30	912	11	0.0120614	0.3666667	GO:0150077	GO:BP	regulation of neuroinflammatory response	16175	20129	GO:00507….
query_1	TRUE	0.0000051	854	912	84	0.0921053	0.0983607	GO:0040012	GO:BP	regulation of locomotion	16175	9900	GO:00400….
query_1	TRUE	0.0000055	115	912	22	0.0241228	0.1913043	GO:0030168	GO:BP	platelet activation	16175	6695	GO:00017….
query_1	TRUE	0.0000055	143	912	25	0.0274123	0.1748252	GO:0060759	GO:BP	regulation of response to cytokine stimulus	16175	14927	GO:00340….
query_1	TRUE	0.0000055	57	912	15	0.0164474	0.2631579	GO:0050871	GO:BP	positive regulation of B cell activation	16175	13319	GO:00421….
query_1	TRUE	0.0000059	407	912	49	0.0537281	0.1203931	GO:0009611	GO:BP	response to wounding	16175	3539	GO:0006950
query_1	TRUE	0.0000060	204	912	31	0.0339912	0.1519608	GO:0051896	GO:BP	regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	16175	13980	GO:00434….
query_1	TRUE	0.0000062	831	912	82	0.0899123	0.0986763	GO:2000145	GO:BP	regulation of cell motility	16175	25493	GO:00400….
query_1	TRUE	0.0000062	15	912	8	0.0087719	0.5333333	GO:0033003	GO:BP	regulation of mast cell activation	16175	7972	GO:00026….
query_1	TRUE	0.0000064	25	912	10	0.0109649	0.4000000	GO:0098581	GO:BP	detection of external biotic stimulus	16175	18798	GO:00095….
query_1	TRUE	0.0000064	25	912	10	0.0109649	0.4000000	GO:0002701	GO:BP	negative regulation of production of molecular mediator of immune response	16175	1219	GO:00024….
query_1	TRUE	0.0000066	164	912	27	0.0296053	0.1646341	GO:0071356	GO:BP	cellular response to tumor necrosis factor	16175	16608	GO:00346….
query_1	TRUE	0.0000067	385	912	47	0.0515351	0.1220779	GO:0043065	GO:BP	positive regulation of apoptotic process	16175	10511	GO:00069….
query_1	TRUE	0.0000070	31	912	11	0.0120614	0.3548387	GO:0030890	GO:BP	positive regulation of B cell proliferation	16175	6955	GO:00308….
query_1	TRUE	0.0000070	31	912	11	0.0120614	0.3548387	GO:0032733	GO:BP	positive regulation of interleukin-10 production	16175	7778	GO:00018….
query_1	TRUE	0.0000072	185	912	29	0.0317982	0.1567568	GO:0007599	GO:BP	hemostasis	16175	3058	GO:0050878
query_1	TRUE	0.0000072	20	912	9	0.0098684	0.4500000	GO:0002825	GO:BP	regulation of T-helper 1 type immune response	16175	1335	GO:00028….
query_1	TRUE	0.0000072	20	912	9	0.0098684	0.4500000	GO:2001185	GO:BP	regulation of CD8-positive, alpha-beta T cell activation	16175	26385	GO:00360….
query_1	TRUE	0.0000072	20	912	9	0.0098684	0.4500000	GO:0050857	GO:BP	positive regulation of antigen receptor-mediated signaling pathway	16175	13305	GO:00099….
query_1	TRUE	0.0000074	249	912	35	0.0383772	0.1405622	GO:0050878	GO:BP	regulation of body fluid levels	16175	13323	GO:0065008
query_1	TRUE	0.0000084	947	912	90	0.0986842	0.0950370	GO:0050790	GO:BP	regulation of catalytic activity	16175	13259	GO:0065009
query_1	TRUE	0.0000086	59	912	15	0.0164474	0.2542373	GO:0010324	GO:BP	membrane invagination	16175	4060	GO:0061024
query_1	TRUE	0.0000089	38	912	12	0.0131579	0.3157895	GO:2000404	GO:BP	regulation of T cell migration	16175	25719	GO:00726….
query_1	TRUE	0.0000091	75	912	17	0.0186404	0.2266667	GO:0030101	GO:BP	natural killer cell activation	16175	6679	GO:0046649
query_1	TRUE	0.0000095	615	912	65	0.0712719	0.1056911	GO:0045597	GO:BP	positive regulation of cell differentiation	16175	11448	GO:00301….
query_1	TRUE	0.0000097	252	912	35	0.0383772	0.1388889	GO:0043122	GO:BP	regulation of canonical NF-kappaB signal transduction	16175	10541	GO:00072….
query_1	TRUE	0.0000099	32	912	11	0.0120614	0.3437500	GO:0045066	GO:BP	regulatory T cell differentiation	16175	11264	GO:0030217
query_1	TRUE	0.0000107	8	912	6	0.0065789	0.7500000	GO:0098883	GO:BP	synapse pruning	16175	18928	GO:00508….
query_1	TRUE	0.0000107	8	912	6	0.0065789	0.7500000	GO:0002579	GO:BP	positive regulation of antigen processing and presentation	16175	1100	GO:00025….
query_1	TRUE	0.0000113	179	912	28	0.0307018	0.1564246	GO:0007596	GO:BP	blood coagulation	16175	3055	GO:00075….
query_1	TRUE	0.0000115	149	912	25	0.0274123	0.1677852	GO:0002753	GO:BP	cytoplasmic pattern recognition receptor signaling pathway	16175	1264	GO:00022….
query_1	TRUE	0.0000115	102	912	20	0.0219298	0.1960784	GO:0038061	GO:BP	non-canonical NF-kappaB signal transduction	16175	9680	GO:0141124
query_1	TRUE	0.0000123	85	912	18	0.0197368	0.2117647	GO:0002220	GO:BP	innate immune response activating cell surface receptor signaling pathway	16175	754	GO:00024….
query_1	TRUE	0.0000139	33	912	11	0.0120614	0.3333333	GO:0002448	GO:BP	mast cell mediated immunity	16175	971	GO:0002444
query_1	TRUE	0.0000139	33	912	11	0.0120614	0.3333333	GO:0045622	GO:BP	regulation of T-helper cell differentiation	16175	11473	GO:00026….
query_1	TRUE	0.0000141	408	912	48	0.0526316	0.1176471	GO:0071396	GO:BP	cellular response to lipid	16175	16648	GO:00339….
query_1	TRUE	0.0000141	27	912	10	0.0109649	0.3703704	GO:0038094	GO:BP	Fc-gamma receptor signaling pathway	16175	9694	GO:0038093
query_1	TRUE	0.0000142	12	912	7	0.0076754	0.5833333	GO:0002643	GO:BP	regulation of tolerance induction	16175	1161	GO:00025….
query_1	TRUE	0.0000151	54	912	14	0.0153509	0.2592593	GO:0060760	GO:BP	positive regulation of response to cytokine stimulus	16175	14928	GO:00340….
query_1	TRUE	0.0000151	54	912	14	0.0153509	0.2592593	GO:0045071	GO:BP	negative regulation of viral genome replication	16175	11269	GO:00190….
query_1	TRUE	0.0000151	235	912	33	0.0361842	0.1404255	GO:0043491	GO:BP	phosphatidylinositol 3-kinase/protein kinase B signal transduction	16175	10736	GO:0141124
query_1	TRUE	0.0000158	78	912	17	0.0186404	0.2179487	GO:0045824	GO:BP	negative regulation of innate immune response	16175	11644	GO:00028….
query_1	TRUE	0.0000162	142	912	24	0.0263158	0.1690141	GO:0007259	GO:BP	cell surface receptor signaling pathway via JAK-STAT	16175	2789	GO:0097696
query_1	TRUE	0.0000173	183	912	28	0.0307018	0.1530055	GO:0050817	GO:BP	coagulation	16175	13279	GO:0032501
query_1	TRUE	0.0000179	4632	912	325	0.3563596	0.0701641	GO:0032502	GO:BP	developmental process	16175	7612	GO:0008150
query_1	TRUE	0.0000181	22	912	9	0.0098684	0.4090909	GO:0032703	GO:BP	negative regulation of interleukin-2 production	16175	7748	GO:00018….
query_1	TRUE	0.0000181	22	912	9	0.0098684	0.4090909	GO:0071624	GO:BP	positive regulation of granulocyte chemotaxis	16175	16804	GO:00026….
query_1	TRUE	0.0000189	34	912	11	0.0120614	0.3235294	GO:0001774	GO:BP	microglial cell activation	16175	439	GO:00022….
query_1	TRUE	0.0000189	34	912	11	0.0120614	0.3235294	GO:0002269	GO:BP	leukocyte activation involved in inflammatory response	16175	801	GO:00069….
query_1	TRUE	0.0000189	34	912	11	0.0120614	0.3235294	GO:2000403	GO:BP	positive regulation of lymphocyte migration	16175	25718	GO:00716….
query_1	TRUE	0.0000193	17	912	8	0.0087719	0.4705882	GO:1903306	GO:BP	negative regulation of regulated secretory pathway	16175	22893	GO:00450….
query_1	TRUE	0.0000193	17	912	8	0.0087719	0.4705882	GO:0032753	GO:BP	positive regulation of interleukin-4 production	16175	7797	GO:00018….
query_1	TRUE	0.0000202	28	912	10	0.0109649	0.3571429	GO:0045589	GO:BP	regulation of regulatory T cell differentiation	16175	11440	GO:00450….
query_1	TRUE	0.0000232	145	912	24	0.0263158	0.1655172	GO:0048872	GO:BP	homeostasis of number of cells	16175	13115	GO:0048871
query_1	TRUE	0.0000250	263	912	35	0.0383772	0.1330798	GO:0006887	GO:BP	exocytosis	16175	2543	GO:00161….
query_1	TRUE	0.0000264	49	912	13	0.0142544	0.2653061	GO:1903556	GO:BP	negative regulation of tumor necrosis factor superfamily cytokine production	16175	23103	GO:00018….
query_1	TRUE	0.0000282	13	912	7	0.0076754	0.5384615	GO:0032695	GO:BP	negative regulation of interleukin-12 production	16175	7741	GO:00018….
query_1	TRUE	0.0000286	9	912	6	0.0065789	0.6666667	GO:0035747	GO:BP	natural killer cell chemotaxis	16175	9212	GO:0048247
query_1	TRUE	0.0000286	9	912	6	0.0065789	0.6666667	GO:2001187	GO:BP	positive regulation of CD8-positive, alpha-beta T cell activation	16175	26387	GO:00360….
query_1	TRUE	0.0000288	29	912	10	0.0109649	0.3448276	GO:0042092	GO:BP	type 2 immune response	16175	9963	GO:0006955
query_1	TRUE	0.0000292	57	912	14	0.0153509	0.2456140	GO:0002711	GO:BP	positive regulation of T cell mediated immunity	16175	1229	GO:00024….
query_1	TRUE	0.0000323	18	912	8	0.0087719	0.4444444	GO:0140131	GO:BP	positive regulation of lymphocyte chemotaxis	16175	19677	GO:00026….
query_1	TRUE	0.0000330	522	912	56	0.0614035	0.1072797	GO:0042327	GO:BP	positive regulation of phosphorylation	16175	10095	GO:00163….
query_1	TRUE	0.0000333	50	912	13	0.0142544	0.2600000	GO:1901224	GO:BP	positive regulation of non-canonical NF-kappaB signal transduction	16175	21318	GO:00380….
query_1	TRUE	0.0000345	510	912	55	0.0603070	0.1078431	GO:0048871	GO:BP	multicellular organismal-level homeostasis	16175	13114	GO:00325….
query_1	TRUE	0.0000345	74	912	16	0.0175439	0.2162162	GO:0030316	GO:BP	osteoclast differentiation	16175	6767	GO:0002573
query_1	TRUE	0.0000345	36	912	11	0.0120614	0.3055556	GO:0002823	GO:BP	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	16175	1333	GO:00024….
query_1	TRUE	0.0000370	149	912	24	0.0263158	0.1610738	GO:0097696	GO:BP	cell surface receptor signaling pathway via STAT	16175	18727	GO:0007166
query_1	TRUE	0.0000381	101	912	19	0.0208333	0.1881188	GO:0051209	GO:BP	release of sequestered calcium ion into cytosol	16175	13568	GO:00512….
query_1	TRUE	0.0000392	564	912	59	0.0646930	0.1046099	GO:0010562	GO:BP	positive regulation of phosphorus metabolic process	16175	4215	GO:00067….
query_1	TRUE	0.0000392	564	912	59	0.0646930	0.1046099	GO:0045937	GO:BP	positive regulation of phosphate metabolic process	16175	11731	GO:00067….
query_1	TRUE	0.0000398	339	912	41	0.0449561	0.1209440	GO:0042060	GO:BP	wound healing	16175	9947	GO:0009611
query_1	TRUE	0.0000399	30	912	10	0.0109649	0.3333333	GO:0072677	GO:BP	eosinophil migration	16175	17495	GO:0097530
query_1	TRUE	0.0000399	500	912	54	0.0592105	0.1080000	GO:0001934	GO:BP	positive regulation of protein phosphorylation	16175	548	GO:00019….
query_1	TRUE	0.0000436	67	912	15	0.0164474	0.2238806	GO:0002752	GO:BP	cell surface pattern recognition receptor signaling pathway	16175	1263	GO:00022….
query_1	TRUE	0.0000437	102	912	19	0.0208333	0.1862745	GO:0051283	GO:BP	negative regulation of sequestering of calcium ion	16175	13619	GO:00485….
query_1	TRUE	0.0000439	59	912	14	0.0153509	0.2372881	GO:0030239	GO:BP	myofibril assembly	16175	6736	GO:00109….
query_1	TRUE	0.0000454	37	912	11	0.0120614	0.2972973	GO:0061900	GO:BP	glial cell activation	16175	15715	GO:00017….
query_1	TRUE	0.0000454	44	912	12	0.0131579	0.2727273	GO:0043030	GO:BP	regulation of macrophage activation	16175	10485	GO:00026….
query_1	TRUE	0.0000454	37	912	11	0.0120614	0.2972973	GO:0002762	GO:BP	negative regulation of myeloid leukocyte differentiation	16175	1273	GO:00025….
query_1	TRUE	0.0000454	37	912	11	0.0120614	0.2972973	GO:0046638	GO:BP	positive regulation of alpha-beta T cell differentiation	16175	12275	GO:00455….
query_1	TRUE	0.0000477	4217	912	297	0.3256579	0.0704292	GO:0048523	GO:BP	negative regulation of cellular process	16175	12806	GO:00099….
query_1	TRUE	0.0000502	103	912	19	0.0208333	0.1844660	GO:0051282	GO:BP	regulation of sequestering of calcium ion	16175	13618	GO:00328….
query_1	TRUE	0.0000507	14	912	7	0.0076754	0.5000000	GO:0010819	GO:BP	regulation of T cell chemotaxis	16175	4431	GO:00108….
query_1	TRUE	0.0000507	14	912	7	0.0076754	0.5000000	GO:0045063	GO:BP	T-helper 1 cell differentiation	16175	11261	GO:00420….
query_1	TRUE	0.0000516	132	912	22	0.0241228	0.1666667	GO:0001959	GO:BP	regulation of cytokine-mediated signaling pathway	16175	568	GO:00099….
query_1	TRUE	0.0000587	25	912	9	0.0098684	0.3600000	GO:1902624	GO:BP	positive regulation of neutrophil migration	16175	22395	GO:00026….
query_1	TRUE	0.0000641	10	912	6	0.0065789	0.6000000	GO:0002524	GO:BP	hypersensitivity	16175	1046	GO:0002438
query_1	TRUE	0.0000641	10	912	6	0.0065789	0.6000000	GO:0002517	GO:BP	T cell tolerance induction	16175	1039	GO:0002507
query_1	TRUE	0.0000650	175	912	26	0.0285088	0.1485714	GO:0051146	GO:BP	striated muscle cell differentiation	16175	13529	GO:0042692
query_1	TRUE	0.0000651	61	912	14	0.0153509	0.2295082	GO:0002526	GO:BP	acute inflammatory response	16175	1048	GO:0006954
query_1	TRUE	0.0000745	32	912	10	0.0109649	0.3125000	GO:0043303	GO:BP	mast cell degranulation	16175	10611	GO:00022….
query_1	TRUE	0.0000745	32	912	10	0.0109649	0.3125000	GO:2000116	GO:BP	regulation of cysteine-type endopeptidase activity	16175	25465	GO:0052548
query_1	TRUE	0.0000761	106	912	19	0.0208333	0.1792453	GO:0051208	GO:BP	sequestering of calcium ion	16175	13567	GO:00068….
query_1	TRUE	0.0000780	39	912	11	0.0120614	0.2820513	GO:0141084	GO:BP	inflammasome-mediated signaling pathway	16175	20015	GO:00027….
query_1	TRUE	0.0000785	20	912	8	0.0087719	0.4000000	GO:0002475	GO:BP	antigen processing and presentation via MHC class Ib	16175	998	GO:0019882
query_1	TRUE	0.0000785	20	912	8	0.0087719	0.4000000	GO:0002295	GO:BP	T-helper cell lineage commitment	16175	827	GO:00420….
query_1	TRUE	0.0000788	62	912	14	0.0153509	0.2258065	GO:0070527	GO:BP	platelet aggregation	16175	16166	GO:00301….
query_1	TRUE	0.0000834	26	912	9	0.0098684	0.3461538	GO:0090022	GO:BP	regulation of neutrophil chemotaxis	16175	17956	GO:00305….
query_1	TRUE	0.0000855	963	912	87	0.0953947	0.0903427	GO:0051094	GO:BP	positive regulation of developmental process	16175	13489	GO:00325….
query_1	TRUE	0.0000866	107	912	19	0.0208333	0.1775701	GO:0051048	GO:BP	negative regulation of secretion	16175	13458	GO:00469….
query_1	TRUE	0.0000875	15	912	7	0.0076754	0.4666667	GO:0002438	GO:BP	acute inflammatory response to antigenic stimulus	16175	961	GO:00024….
query_1	TRUE	0.0000908	1608	912	131	0.1436404	0.0814677	GO:0032879	GO:BP	regulation of localization	16175	7876	GO:00507….
query_1	TRUE	0.0000912	47	912	12	0.0131579	0.2553191	GO:0038093	GO:BP	Fc receptor signaling pathway	16175	9693	GO:0002768
query_1	TRUE	0.0000912	47	912	12	0.0131579	0.2553191	GO:0042130	GO:BP	negative regulation of T cell proliferation	16175	9984	GO:00420….
query_1	TRUE	0.0000912	47	912	12	0.0131579	0.2553191	GO:0001961	GO:BP	positive regulation of cytokine-mediated signaling pathway	16175	570	GO:00019….
query_1	TRUE	0.0000956	179	912	26	0.0285088	0.1452514	GO:0051924	GO:BP	regulation of calcium ion transport	16175	13997	GO:00068….
query_1	TRUE	0.0000983	33	912	10	0.0109649	0.3030303	GO:0002474	GO:BP	antigen processing and presentation of peptide antigen via MHC class I	16175	997	GO:0048002
query_1	TRUE	0.0000983	33	912	10	0.0109649	0.3030303	GO:2000516	GO:BP	positive regulation of CD4-positive, alpha-beta T cell activation	16175	25819	GO:00357….
query_1	TRUE	0.0000983	33	912	10	0.0109649	0.3030303	GO:0002279	GO:BP	mast cell activation involved in immune response	16175	811	GO:00022….
query_1	TRUE	0.0001020	3144	912	229	0.2510965	0.0728372	GO:0007275	GO:BP	multicellular organism development	16175	2802	GO:00325….
query_1	TRUE	0.0001127	4	912	4	0.0043860	1.0000000	GO:0002586	GO:BP	regulation of antigen processing and presentation of peptide antigen via MHC class II	16175	1107	GO:00024….
query_1	TRUE	0.0001127	4	912	4	0.0043860	1.0000000	GO:0150062	GO:BP	complement-mediated synapse pruning	16175	20118	GO:0098883
query_1	TRUE	0.0001137	48	912	12	0.0131579	0.2500000	GO:0070227	GO:BP	lymphocyte apoptotic process	16175	15997	GO:0071887
query_1	TRUE	0.0001151	27	912	9	0.0098684	0.3333333	GO:0002717	GO:BP	positive regulation of natural killer cell mediated immunity	16175	1235	GO:00022….
query_1	TRUE	0.0001151	27	912	9	0.0098684	0.3333333	GO:0048245	GO:BP	eosinophil chemotaxis	16175	12603	GO:00716….
query_1	TRUE	0.0001166	192	912	27	0.0296053	0.1406250	GO:0043123	GO:BP	positive regulation of canonical NF-kappaB signal transduction	16175	10542	GO:00072….
query_1	TRUE	0.0001170	887	912	81	0.0888158	0.0913191	GO:0051174	GO:BP	regulation of phosphorus metabolic process	16175	13554	GO:00067….
query_1	TRUE	0.0001170	887	912	81	0.0888158	0.0913191	GO:0019220	GO:BP	regulation of phosphate metabolic process	16175	5597	GO:00067….
query_1	TRUE	0.0001182	160	912	24	0.0263158	0.1500000	GO:0097553	GO:BP	calcium ion transmembrane import into cytosol	16175	18700	GO:0070588
query_1	TRUE	0.0001186	7	912	5	0.0054825	0.7142857	GO:2000501	GO:BP	regulation of natural killer cell chemotaxis	16175	25807	GO:00357….
query_1	TRUE	0.0001186	7	912	5	0.0054825	0.7142857	GO:0001915	GO:BP	negative regulation of T cell mediated cytotoxicity	16175	532	GO:00019….
query_1	TRUE	0.0001186	7	912	5	0.0054825	0.7142857	GO:0002645	GO:BP	positive regulation of tolerance induction	16175	1163	GO:00025….
query_1	TRUE	0.0001238	249	912	32	0.0350877	0.1285141	GO:0070588	GO:BP	calcium ion transmembrane transport	16175	16193	GO:00068….
query_1	TRUE	0.0001253	41	912	11	0.0120614	0.2682927	GO:0033628	GO:BP	regulation of cell adhesion mediated by integrin	16175	8329	GO:00301….
query_1	TRUE	0.0001253	11	912	6	0.0065789	0.5454545	GO:0043374	GO:BP	CD8-positive, alpha-beta T cell differentiation	16175	10651	GO:00360….
query_1	TRUE	0.0001280	34	912	10	0.0109649	0.2941176	GO:1902622	GO:BP	regulation of neutrophil migration	16175	22393	GO:00026….
query_1	TRUE	0.0001280	34	912	10	0.0109649	0.2941176	GO:0001916	GO:BP	positive regulation of T cell mediated cytotoxicity	16175	533	GO:00019….
query_1	TRUE	0.0001285	792	912	74	0.0811404	0.0934343	GO:0042325	GO:BP	regulation of phosphorylation	16175	10093	GO:00163….
query_1	TRUE	0.0001330	65	912	14	0.0153509	0.2153846	GO:0007260	GO:BP	tyrosine phosphorylation of STAT protein	16175	2790	GO:00072….
query_1	TRUE	0.0001385	49	912	12	0.0131579	0.2448980	GO:0045670	GO:BP	regulation of osteoclast differentiation	16175	11521	GO:00027….
query_1	TRUE	0.0001399	16	912	7	0.0076754	0.4375000	GO:0060263	GO:BP	regulation of respiratory burst	16175	14480	GO:00192….
query_1	TRUE	0.0001399	16	912	7	0.0076754	0.4375000	GO:0016045	GO:BP	detection of bacterium	16175	5078	GO:00096….
query_1	TRUE	0.0001531	632	912	62	0.0679825	0.0981013	GO:0031401	GO:BP	positive regulation of protein modification process	16175	7157	GO:00313….
query_1	TRUE	0.0001558	28	912	9	0.0098684	0.3214286	GO:2000406	GO:BP	positive regulation of T cell migration	16175	25721	GO:00726….
query_1	TRUE	0.0001581	42	912	11	0.0120614	0.2619048	GO:0071622	GO:BP	regulation of granulocyte chemotaxis	16175	16802	GO:00026….
query_1	TRUE	0.0001669	22	912	8	0.0087719	0.3636364	GO:0032633	GO:BP	interleukin-4 production	16175	7680	GO:0001816
query_1	TRUE	0.0001669	22	912	8	0.0087719	0.3636364	GO:0032673	GO:BP	regulation of interleukin-4 production	16175	7719	GO:00018….
query_1	TRUE	0.0001669	22	912	8	0.0087719	0.3636364	GO:0002483	GO:BP	antigen processing and presentation of endogenous peptide antigen	16175	1006	GO:00198….
query_1	TRUE	0.0001746	103	912	18	0.0197368	0.1747573	GO:0002520	GO:BP	immune system development	16175	1042	GO:00023….
query_1	TRUE	0.0001746	103	912	18	0.0197368	0.1747573	GO:0055002	GO:BP	striated muscle cell development	16175	14191	GO:00511….
query_1	TRUE	0.0001765	1259	912	106	0.1162281	0.0841938	GO:0016192	GO:BP	vesicle-mediated transport	16175	5168	GO:00068….
query_1	TRUE	0.0001948	85	912	16	0.0175439	0.1882353	GO:0034109	GO:BP	homotypic cell-cell adhesion	16175	8417	GO:0098609
query_1	TRUE	0.0002061	1249	912	105	0.1151316	0.0840673	GO:0042592	GO:BP	homeostatic process	16175	10252	GO:0008150
query_1	TRUE	0.0002102	29	912	9	0.0098684	0.3103448	GO:0032689	GO:BP	negative regulation of type II interferon production	16175	7735	GO:00018….
query_1	TRUE	0.0002102	29	912	9	0.0098684	0.3103448	GO:0045920	GO:BP	negative regulation of exocytosis	16175	11714	GO:00068….
query_1	TRUE	0.0002102	29	912	9	0.0098684	0.3103448	GO:0072539	GO:BP	T-helper 17 cell differentiation	16175	17437	GO:00420….
query_1	TRUE	0.0002157	36	912	10	0.0109649	0.2777778	GO:0070228	GO:BP	regulation of lymphocyte apoptotic process	16175	15998	GO:00702….
query_1	TRUE	0.0002157	36	912	10	0.0109649	0.2777778	GO:0140632	GO:BP	canonical inflammasome complex assembly	16175	19839	GO:00650….
query_1	TRUE	0.0002184	17	912	7	0.0076754	0.4117647	GO:0002862	GO:BP	negative regulation of inflammatory response to antigenic stimulus	16175	1372	GO:00024….
query_1	TRUE	0.0002184	17	912	7	0.0076754	0.4117647	GO:0001562	GO:BP	response to protozoan	16175	351	GO:0051707
query_1	TRUE	0.0002184	17	912	7	0.0076754	0.4117647	GO:0042832	GO:BP	defense response to protozoan	16175	10388	GO:00015….
query_1	TRUE	0.0002184	17	912	7	0.0076754	0.4117647	GO:0001773	GO:BP	myeloid dendritic cell activation	16175	438	GO:0002274
query_1	TRUE	0.0002229	135	912	21	0.0230263	0.1555556	GO:0051260	GO:BP	protein homooligomerization	16175	13607	GO:0051259
query_1	TRUE	0.0002256	12	912	6	0.0065789	0.5000000	GO:0032490	GO:BP	detection of molecule of bacterial origin	16175	7601	GO:00022….
query_1	TRUE	0.0002256	12	912	6	0.0065789	0.5000000	GO:0030889	GO:BP	negative regulation of B cell proliferation	16175	6954	GO:00308….
query_1	TRUE	0.0002256	12	912	6	0.0065789	0.5000000	GO:1903975	GO:BP	regulation of glial cell migration	16175	23432	GO:00083….
query_1	TRUE	0.0002256	12	912	6	0.0065789	0.5000000	GO:0070486	GO:BP	leukocyte aggregation	16175	16147	GO:0007159
query_1	TRUE	0.0002331	443	912	47	0.0515351	0.1060948	GO:0043549	GO:BP	regulation of kinase activity	16175	10763	GO:00423….
query_1	TRUE	0.0002339	23	912	8	0.0087719	0.3478261	GO:0002363	GO:BP	alpha-beta T cell lineage commitment	16175	895	GO:00023….
query_1	TRUE	0.0002339	23	912	8	0.0087719	0.3478261	GO:0045577	GO:BP	regulation of B cell differentiation	16175	11428	GO:00301….
query_1	TRUE	0.0002339	23	912	8	0.0087719	0.3478261	GO:0043373	GO:BP	CD4-positive, alpha-beta T cell lineage commitment	16175	10650	GO:00023….
query_1	TRUE	0.0002388	258	912	32	0.0350877	0.1240310	GO:0033674	GO:BP	positive regulation of kinase activity	16175	8346	GO:00423….
query_1	TRUE	0.0002388	60	912	13	0.0142544	0.2166667	GO:0140895	GO:BP	cell surface toll-like receptor signaling pathway	16175	19927	GO:0002752
query_1	TRUE	0.0002732	37	912	10	0.0109649	0.2702703	GO:0072538	GO:BP	T-helper 17 type immune response	16175	17436	GO:0002460
query_1	TRUE	0.0002758	30	912	9	0.0098684	0.3000000	GO:0046633	GO:BP	alpha-beta T cell proliferation	16175	12270	GO:00420….
query_1	TRUE	0.0002758	30	912	9	0.0098684	0.3000000	GO:0002431	GO:BP	Fc receptor mediated stimulatory signaling pathway	16175	954	GO:0002429
query_1	TRUE	0.0002778	345	912	39	0.0427632	0.1130435	GO:0051090	GO:BP	regulation of DNA-binding transcription factor activity	16175	13485	GO:00063….
query_1	TRUE	0.0002778	8	912	5	0.0054825	0.6250000	GO:0002664	GO:BP	regulation of T cell tolerance induction	16175	1182	GO:00025….
query_1	TRUE	0.0002778	8	912	5	0.0054825	0.6250000	GO:0140507	GO:BP	granzyme-mediated programmed cell death signaling pathway	16175	19803	GO:00071….
query_1	TRUE	0.0002778	8	912	5	0.0054825	0.6250000	GO:2001198	GO:BP	regulation of dendritic cell differentiation	16175	26398	GO:00970….
query_1	TRUE	0.0003007	744	912	69	0.0756579	0.0927419	GO:0001932	GO:BP	regulation of protein phosphorylation	16175	546	GO:00064….
query_1	TRUE	0.0003203	649	912	62	0.0679825	0.0955316	GO:0046903	GO:BP	secretion	16175	12430	GO:0006810
query_1	TRUE	0.0003247	24	912	8	0.0087719	0.3333333	GO:0031664	GO:BP	regulation of lipopolysaccharide-mediated signaling pathway	16175	7268	GO:00028….
query_1	TRUE	0.0003247	1132	912	96	0.1052632	0.0848057	GO:0016310	GO:BP	phosphorylation	16175	5198	GO:0006796
query_1	TRUE	0.0003247	24	912	8	0.0087719	0.3333333	GO:0002360	GO:BP	T cell lineage commitment	16175	892	GO:00302….
query_1	TRUE	0.0003247	24	912	8	0.0087719	0.3333333	GO:0043369	GO:BP	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	16175	10646	GO:00023….
query_1	TRUE	0.0003247	24	912	8	0.0087719	0.3333333	GO:2000515	GO:BP	negative regulation of CD4-positive, alpha-beta T cell activation	16175	25818	GO:00357….
query_1	TRUE	0.0003250	18	912	7	0.0076754	0.3888889	GO:0002755	GO:BP	MyD88-dependent toll-like receptor signaling pathway	16175	1266	GO:0002224
query_1	TRUE	0.0003250	18	912	7	0.0076754	0.3888889	GO:0072540	GO:BP	T-helper 17 cell lineage commitment	16175	17438	GO:00022….
query_1	TRUE	0.0003442	610	912	59	0.0646930	0.0967213	GO:0043066	GO:BP	negative regulation of apoptotic process	16175	10512	GO:00069….
query_1	TRUE	0.0003471	80	912	15	0.0164474	0.1875000	GO:0045069	GO:BP	regulation of viral genome replication	16175	11267	GO:00190….
query_1	TRUE	0.0003633	54	912	12	0.0131579	0.2222222	GO:0042531	GO:BP	positive regulation of tyrosine phosphorylation of STAT protein	16175	10227	GO:00072….
query_1	TRUE	0.0003815	13	912	6	0.0065789	0.4615385	GO:0010820	GO:BP	positive regulation of T cell chemotaxis	16175	4432	GO:00108….
query_1	TRUE	0.0003815	13	912	6	0.0065789	0.4615385	GO:0002827	GO:BP	positive regulation of T-helper 1 type immune response	16175	1337	GO:00028….
query_1	TRUE	0.0003987	63	912	13	0.0142544	0.2063492	GO:0042509	GO:BP	regulation of tyrosine phosphorylation of STAT protein	16175	10226	GO:00072….
query_1	TRUE	0.0004132	242	912	30	0.0328947	0.1239669	GO:0019058	GO:BP	viral life cycle	16175	5555	GO:0016032
query_1	TRUE	0.0004323	163	912	23	0.0252193	0.1411043	GO:0043270	GO:BP	positive regulation of monoatomic ion transport	16175	10594	GO:00068….
query_1	TRUE	0.0004452	243	912	30	0.0328947	0.1234568	GO:1901342	GO:BP	regulation of vasculature development	16175	21401	GO:00019….
query_1	TRUE	0.0004453	25	912	8	0.0087719	0.3200000	GO:0002861	GO:BP	regulation of inflammatory response to antigenic stimulus	16175	1371	GO:00024….
query_1	TRUE	0.0004526	47	912	11	0.0120614	0.2340426	GO:0032720	GO:BP	negative regulation of tumor necrosis factor production	16175	7765	GO:00326….
query_1	TRUE	0.0004548	630	912	60	0.0657895	0.0952381	GO:0043069	GO:BP	negative regulation of programmed cell death	16175	10515	GO:00125….
query_1	TRUE	0.0004614	5	912	4	0.0043860	0.8000000	GO:0002580	GO:BP	regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	16175	1101	GO:00025….
query_1	TRUE	0.0004614	5	912	4	0.0043860	0.8000000	GO:0043378	GO:BP	positive regulation of CD8-positive, alpha-beta T cell differentiation	16175	10655	GO:00433….
query_1	TRUE	0.0004614	32	912	9	0.0098684	0.2812500	GO:0002724	GO:BP	regulation of T cell cytokine production	16175	1242	GO:00023….
query_1	TRUE	0.0004614	5	912	4	0.0043860	0.8000000	GO:1904149	GO:BP	regulation of microglial cell mediated cytotoxicity	16175	23570	GO:00019….
query_1	TRUE	0.0004614	5	912	4	0.0043860	0.8000000	GO:2000503	GO:BP	positive regulation of natural killer cell chemotaxis	16175	25809	GO:00357….
query_1	TRUE	0.0004614	5	912	4	0.0043860	0.8000000	GO:2000523	GO:BP	regulation of T cell costimulation	16175	25826	GO:00312….
query_1	TRUE	0.0004614	341	912	38	0.0416667	0.1114370	GO:0043269	GO:BP	regulation of monoatomic ion transport	16175	10593	GO:00068….
query_1	TRUE	0.0004614	617	912	59	0.0646930	0.0956240	GO:0051093	GO:BP	negative regulation of developmental process	16175	13488	GO:00325….
query_1	TRUE	0.0004614	5	912	4	0.0043860	0.8000000	GO:0090634	GO:BP	microglial cell mediated cytotoxicity	16175	18380	GO:00019….
query_1	TRUE	0.0004614	32	912	9	0.0098684	0.2812500	GO:0002369	GO:BP	T cell cytokine production	16175	901	GO:00023….
query_1	TRUE	0.0004614	5	912	4	0.0043860	0.8000000	GO:0031394	GO:BP	positive regulation of prostaglandin biosynthetic process	16175	7151	GO:00015….
query_1	TRUE	0.0004614	64	912	13	0.0142544	0.2031250	GO:0019731	GO:BP	antibacterial humoral response	16175	6022	GO:00197….
query_1	TRUE	0.0004689	19	912	7	0.0076754	0.3684211	GO:0043029	GO:BP	T cell homeostasis	16175	10484	GO:0002260
query_1	TRUE	0.0004689	19	912	7	0.0076754	0.3684211	GO:1900017	GO:BP	positive regulation of cytokine production involved in inflammatory response	16175	20328	GO:00018….
query_1	TRUE	0.0004689	19	912	7	0.0076754	0.3684211	GO:0050860	GO:BP	negative regulation of T cell receptor signaling pathway	16175	13308	GO:00508….
query_1	TRUE	0.0004736	577	912	56	0.0614035	0.0970537	GO:0043085	GO:BP	positive regulation of catalytic activity	16175	10518	GO:00440….
query_1	TRUE	0.0004949	233	912	29	0.0317982	0.1244635	GO:0006874	GO:BP	intracellular calcium ion homeostasis	16175	2532	GO:00300….
query_1	TRUE	0.0005289	40	912	10	0.0109649	0.2500000	GO:0045620	GO:BP	negative regulation of lymphocyte differentiation	16175	11471	GO:00300….
query_1	TRUE	0.0005289	40	912	10	0.0109649	0.2500000	GO:0050691	GO:BP	regulation of defense response to virus by host	16175	13221	GO:0050688
query_1	TRUE	0.0005385	48	912	11	0.0120614	0.2291667	GO:0071260	GO:BP	cellular response to mechanical stimulus	16175	16518	GO:00096….
query_1	TRUE	0.0005385	48	912	11	0.0120614	0.2291667	GO:0071496	GO:BP	cellular response to external stimulus	16175	16729	GO:0009605
query_1	TRUE	0.0005477	1120	912	94	0.1030702	0.0839286	GO:0023057	GO:BP	negative regulation of signaling	16175	6642	GO:00230….
query_1	TRUE	0.0005477	93	912	16	0.0175439	0.1720430	GO:0051928	GO:BP	positive regulation of calcium ion transport	16175	13999	GO:00068….
query_1	TRUE	0.0005477	9	912	5	0.0054825	0.5555556	GO:0002765	GO:BP	immune response-inhibiting signal transduction	16175	1276	GO:0002764
query_1	TRUE	0.0005477	9	912	5	0.0054825	0.5555556	GO:0071639	GO:BP	positive regulation of monocyte chemotactic protein-1 production	16175	16816	GO:00327….
query_1	TRUE	0.0005477	9	912	5	0.0054825	0.5555556	GO:2000668	GO:BP	regulation of dendritic cell apoptotic process	16175	25943	GO:00970….
query_1	TRUE	0.0005477	9	912	5	0.0054825	0.5555556	GO:0070383	GO:BP	DNA cytosine deamination	16175	16090	GO:0045006
query_1	TRUE	0.0005477	9	912	5	0.0054825	0.5555556	GO:0002604	GO:BP	regulation of dendritic cell antigen processing and presentation	16175	1125	GO:00024….
query_1	TRUE	0.0005477	9	912	5	0.0054825	0.5555556	GO:0097048	GO:BP	dendritic cell apoptotic process	16175	18461	GO:0071887
query_1	TRUE	0.0005477	9	912	5	0.0054825	0.5555556	GO:2000508	GO:BP	regulation of dendritic cell chemotaxis	16175	25811	GO:00024….
query_1	TRUE	0.0005477	9	912	5	0.0054825	0.5555556	GO:0001771	GO:BP	immunological synapse formation	16175	437	GO:00099….
query_1	TRUE	0.0005539	103	912	17	0.0186404	0.1650485	GO:0039531	GO:BP	regulation of cytoplasmic pattern recognition receptor signaling pathway	16175	9804	GO:00027….
query_1	TRUE	0.0005768	501	912	50	0.0548246	0.0998004	GO:0008285	GO:BP	negative regulation of cell population proliferation	16175	3152	GO:00082….
query_1	TRUE	0.0005780	26	912	8	0.0087719	0.3076923	GO:0090025	GO:BP	regulation of monocyte chemotaxis	16175	17959	GO:00025….
query_1	TRUE	0.0005797	33	912	9	0.0098684	0.2727273	GO:0046636	GO:BP	negative regulation of alpha-beta T cell activation	16175	12273	GO:00466….
query_1	TRUE	0.0005933	14	912	6	0.0065789	0.4285714	GO:0050862	GO:BP	positive regulation of T cell receptor signaling pathway	16175	13310	GO:00508….
query_1	TRUE	0.0005933	14	912	6	0.0065789	0.4285714	GO:0002283	GO:BP	neutrophil activation involved in immune response	16175	815	GO:00022….
query_1	TRUE	0.0006321	708	912	65	0.0712719	0.0918079	GO:0030029	GO:BP	actin filament-based process	16175	6653	GO:0009987
query_1	TRUE	0.0006435	41	912	10	0.0109649	0.2439024	GO:0009620	GO:BP	response to fungus	16175	3544	GO:0051707
query_1	TRUE	0.0006435	41	912	10	0.0109649	0.2439024	GO:0030225	GO:BP	macrophage differentiation	16175	6733	GO:00025….
query_1	TRUE	0.0006504	237	912	29	0.0317982	0.1223629	GO:0045765	GO:BP	regulation of angiogenesis	16175	11601	GO:00015….
query_1	TRUE	0.0006555	20	912	7	0.0076754	0.3500000	GO:0002719	GO:BP	negative regulation of cytokine production involved in immune response	16175	1237	GO:00018….
query_1	TRUE	0.0006555	20	912	7	0.0076754	0.3500000	GO:0002828	GO:BP	regulation of type 2 immune response	16175	1338	GO:00420….
query_1	TRUE	0.0006555	20	912	7	0.0076754	0.3500000	GO:0019885	GO:BP	antigen processing and presentation of endogenous peptide antigen via MHC class I	16175	6063	GO:00024….
query_1	TRUE	0.0006555	20	912	7	0.0076754	0.3500000	GO:0045591	GO:BP	positive regulation of regulatory T cell differentiation	16175	11442	GO:00450….
query_1	TRUE	0.0007310	1115	912	93	0.1019737	0.0834081	GO:0010648	GO:BP	negative regulation of cell communication	16175	4294	GO:00071….
query_1	TRUE	0.0007348	34	912	9	0.0098684	0.2647059	GO:0044546	GO:BP	NLRP3 inflammasome complex assembly	16175	11065	GO:0140632
query_1	TRUE	0.0007348	34	912	9	0.0098684	0.2647059	GO:0050798	GO:BP	activated T cell proliferation	16175	13265	GO:0042098
query_1	TRUE	0.0007636	27	912	8	0.0087719	0.2962963	GO:0043372	GO:BP	positive regulation of CD4-positive, alpha-beta T cell differentiation	16175	10649	GO:00433….
query_1	TRUE	0.0007682	50	912	11	0.0120614	0.2200000	GO:0010543	GO:BP	regulation of platelet activation	16175	4202	GO:00301….
query_1	TRUE	0.0007804	96	912	16	0.0175439	0.1666667	GO:0007200	GO:BP	phospholipase C-activating G protein-coupled receptor signaling pathway	16175	2758	GO:0007186
query_1	TRUE	0.0008103	77	912	14	0.0153509	0.1818182	GO:0052548	GO:BP	regulation of endopeptidase activity	16175	14134	GO:0052547
query_1	TRUE	0.0008126	1045	912	88	0.0964912	0.0842105	GO:0006468	GO:BP	protein phosphorylation	16175	2207	GO:00163….
query_1	TRUE	0.0008185	182	912	24	0.0263158	0.1318681	GO:0051651	GO:BP	maintenance of location in cell	16175	13864	GO:00099….
query_1	TRUE	0.0008431	632	912	59	0.0646930	0.0933544	GO:0030036	GO:BP	actin cytoskeleton organization	16175	6660	GO:00070….
query_1	TRUE	0.0008585	241	912	29	0.0317982	0.1203320	GO:0045860	GO:BP	positive regulation of protein kinase activity	16175	11672	GO:00019….
query_1	TRUE	0.0008585	87	912	15	0.0164474	0.1724138	GO:1903305	GO:BP	regulation of regulated secretory pathway	16175	22892	GO:00171….
query_1	TRUE	0.0009066	15	912	6	0.0065789	0.4000000	GO:0032693	GO:BP	negative regulation of interleukin-10 production	16175	7739	GO:00018….
query_1	TRUE	0.0009066	15	912	6	0.0065789	0.4000000	GO:0002716	GO:BP	negative regulation of natural killer cell mediated immunity	16175	1234	GO:00022….
query_1	TRUE	0.0009066	172	912	23	0.0252193	0.1337209	GO:0034764	GO:BP	positive regulation of transmembrane transport	16175	8733	GO:00347….
query_1	TRUE	0.0009066	15	912	6	0.0065789	0.4000000	GO:0045869	GO:BP	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	16175	11677	GO:00396….
query_1	TRUE	0.0009066	15	912	6	0.0065789	0.4000000	GO:0045953	GO:BP	negative regulation of natural killer cell mediated cytotoxicity	16175	11745	GO:00019….
query_1	TRUE	0.0009066	15	912	6	0.0065789	0.4000000	GO:0021602	GO:BP	cranial nerve morphogenesis	16175	6185	GO:00096….
query_1	TRUE	0.0009181	35	912	9	0.0098684	0.2571429	GO:0045581	GO:BP	negative regulation of T cell differentiation	16175	11432	GO:00302….
query_1	TRUE	0.0009340	118	912	18	0.0197368	0.1525424	GO:0055001	GO:BP	muscle cell development	16175	14190	GO:00426….
query_1	TRUE	0.0009563	184	912	24	0.0263158	0.1304348	GO:0051259	GO:BP	protein complex oligomerization	16175	13606	GO:0065003
query_1	TRUE	0.0009619	69	912	13	0.0142544	0.1884058	GO:0141060	GO:BP	disruption of anatomical structure in another organism	16175	19996	GO:0044419
query_1	TRUE	0.0009624	60	912	12	0.0131579	0.2000000	GO:0031640	GO:BP	killing of cells of another organism	16175	7250	GO:00019….
query_1	TRUE	0.0009624	60	912	12	0.0131579	0.2000000	GO:0141061	GO:BP	disruption of cell in another organism	16175	19997	GO:0141060
query_1	TRUE	0.0009828	28	912	8	0.0087719	0.2857143	GO:2000107	GO:BP	negative regulation of leukocyte apoptotic process	16175	25458	GO:00430….
query_1	TRUE	0.0009828	10	912	5	0.0054825	0.5000000	GO:0043320	GO:BP	natural killer cell degranulation	16175	10628	GO:00023….
query_1	TRUE	0.0009828	10	912	5	0.0054825	0.5000000	GO:2000425	GO:BP	regulation of apoptotic cell clearance	16175	25740	GO:00432….
query_1	TRUE	0.0009978	1260	912	102	0.1118421	0.0809524	GO:0009888	GO:BP	tissue development	16175	3748	GO:0048856
query_1	TRUE	0.0010152	208	912	26	0.0285088	0.1250000	GO:0051091	GO:BP	positive regulation of DNA-binding transcription factor activity	16175	13486	GO:00440….
query_1	TRUE	0.0010724	583	912	55	0.0603070	0.0943396	GO:0032940	GO:BP	secretion by cell	16175	7926	GO:00469….
query_1	TRUE	0.0010858	1829	912	139	0.1524123	0.0759978	GO:0009653	GO:BP	anatomical structure morphogenesis	16175	3571	GO:00325….
query_1	TRUE	0.0011022	1070	912	89	0.0975877	0.0831776	GO:0009968	GO:BP	negative regulation of signal transduction	16175	3806	GO:00071….
query_1	TRUE	0.0011096	221	912	27	0.0296053	0.1221719	GO:0006898	GO:BP	receptor-mediated endocytosis	16175	2552	GO:0006897
query_1	TRUE	0.0011386	36	912	9	0.0098684	0.2500000	GO:0141085	GO:BP	regulation of inflammasome-mediated signaling pathway	16175	20016	GO:00395….
query_1	TRUE	0.0011515	44	912	10	0.0109649	0.2272727	GO:2000351	GO:BP	regulation of endothelial cell apoptotic process	16175	25670	GO:00429….
query_1	TRUE	0.0011651	6	912	4	0.0043860	0.6666667	GO:0099046	GO:BP	clearance of foreign intracellular nucleic acids	16175	19019	GO:0140546
query_1	TRUE	0.0011651	246	912	29	0.0317982	0.1178862	GO:0055074	GO:BP	calcium ion homeostasis	16175	14230	GO:00550….
query_1	TRUE	0.0011651	6	912	4	0.0043860	0.6666667	GO:0034136	GO:BP	negative regulation of toll-like receptor 2 signaling pathway	16175	8444	GO:00026….
query_1	TRUE	0.0011651	6	912	4	0.0043860	0.6666667	GO:2000554	GO:BP	regulation of T-helper 1 cell cytokine production	16175	25855	GO:00027….
query_1	TRUE	0.0011651	6	912	4	0.0043860	0.6666667	GO:0001794	GO:BP	type IIa hypersensitivity	16175	451	GO:0002445
query_1	TRUE	0.0011651	6	912	4	0.0043860	0.6666667	GO:2000556	GO:BP	positive regulation of T-helper 1 cell cytokine production	16175	25857	GO:00027….
query_1	TRUE	0.0011651	131	912	19	0.0208333	0.1450382	GO:0043409	GO:BP	negative regulation of MAPK cascade	16175	10677	GO:00001….
query_1	TRUE	0.0011651	6	912	4	0.0043860	0.6666667	GO:0044355	GO:BP	clearance of foreign intracellular DNA	16175	10971	GO:0099046
query_1	TRUE	0.0011651	6	912	4	0.0043860	0.6666667	GO:0140970	GO:BP	AIM2 inflammasome complex assembly	16175	19954	GO:0065003
query_1	TRUE	0.0011651	110	912	17	0.0186404	0.1545455	GO:0032606	GO:BP	type I interferon production	16175	7654	GO:0001816
query_1	TRUE	0.0011651	6	912	4	0.0043860	0.6666667	GO:0002606	GO:BP	positive regulation of dendritic cell antigen processing and presentation	16175	1127	GO:00024….
query_1	TRUE	0.0011651	110	912	17	0.0186404	0.1545455	GO:0032479	GO:BP	regulation of type I interferon production	16175	7590	GO:00018….
query_1	TRUE	0.0011651	6	912	4	0.0043860	0.6666667	GO:0002583	GO:BP	regulation of antigen processing and presentation of peptide antigen	16175	1104	GO:00025….
query_1	TRUE	0.0011651	6	912	4	0.0043860	0.6666667	GO:0001788	GO:BP	antibody-dependent cellular cytotoxicity	16175	450	GO:00017….
query_1	TRUE	0.0011651	6	912	4	0.0043860	0.6666667	GO:0035744	GO:BP	T-helper 1 cell cytokine production	16175	9209	GO:00357….
query_1	TRUE	0.0011651	6	912	4	0.0043860	0.6666667	GO:0031622	GO:BP	positive regulation of fever generation	16175	7239	GO:00016….
query_1	TRUE	0.0011651	6	912	4	0.0043860	0.6666667	GO:0002445	GO:BP	type II hypersensitivity	16175	968	GO:00024….
query_1	TRUE	0.0011651	6	912	4	0.0043860	0.6666667	GO:0033004	GO:BP	negative regulation of mast cell activation	16175	7973	GO:00026….
query_1	TRUE	0.0011651	6	912	4	0.0043860	0.6666667	GO:0050859	GO:BP	negative regulation of B cell receptor signaling pathway	16175	13307	GO:00508….
query_1	TRUE	0.0012063	22	912	7	0.0076754	0.3181818	GO:0034121	GO:BP	regulation of toll-like receptor signaling pathway	16175	8429	GO:00022….
query_1	TRUE	0.0012218	884	912	76	0.0833333	0.0859729	GO:0010629	GO:BP	negative regulation of gene expression	16175	4275	GO:00104….
query_1	TRUE	0.0012372	29	912	8	0.0087719	0.2758621	GO:0046640	GO:BP	regulation of alpha-beta T cell proliferation	16175	12277	GO:00421….
query_1	TRUE	0.0012381	71	912	13	0.0142544	0.1830986	GO:0002377	GO:BP	immunoglobulin production	16175	907	GO:0002440
query_1	TRUE	0.0012476	412	912	42	0.0460526	0.1019417	GO:0045859	GO:BP	regulation of protein kinase activity	16175	11671	GO:00019….
query_1	TRUE	0.0012990	16	912	6	0.0065789	0.3750000	GO:0034134	GO:BP	toll-like receptor 2 signaling pathway	16175	8442	GO:0140895
query_1	TRUE	0.0012990	16	912	6	0.0065789	0.3750000	GO:0034112	GO:BP	positive regulation of homotypic cell-cell adhesion	16175	8420	GO:00224….
query_1	TRUE	0.0013196	400	912	41	0.0449561	0.1025000	GO:0001525	GO:BP	angiogenesis	16175	330	GO:00485….
query_1	TRUE	0.0013219	575	912	54	0.0592105	0.0939130	GO:0044092	GO:BP	negative regulation of molecular function	16175	10914	GO:0065009
query_1	TRUE	0.0013311	236	912	28	0.0307018	0.1186441	GO:0050678	GO:BP	regulation of epithelial cell proliferation	16175	13212	GO:00421….
query_1	TRUE	0.0013695	37	912	9	0.0098684	0.2432432	GO:0043277	GO:BP	apoptotic cell clearance	16175	10598	GO:0006909
query_1	TRUE	0.0014354	112	912	17	0.0186404	0.1517857	GO:0061041	GO:BP	regulation of wound healing	16175	15157	GO:00420….
query_1	TRUE	0.0014614	3	912	3	0.0032895	1.0000000	GO:0071613	GO:BP	granzyme B production	16175	16799	GO:0002440
query_1	TRUE	0.0014614	3	912	3	0.0032895	1.0000000	GO:0002408	GO:BP	myeloid dendritic cell chemotaxis	16175	932	GO:00024….
query_1	TRUE	0.0014614	3	912	3	0.0032895	1.0000000	GO:0071661	GO:BP	regulation of granzyme B production	16175	16838	GO:00018….
query_1	TRUE	0.0014614	3	912	3	0.0032895	1.0000000	GO:0002277	GO:BP	myeloid dendritic cell activation involved in immune response	16175	809	GO:00017….
query_1	TRUE	0.0014614	3	912	3	0.0032895	1.0000000	GO:2000547	GO:BP	regulation of dendritic cell dendrite assembly	16175	25848	GO:00970….
query_1	TRUE	0.0014614	3	912	3	0.0032895	1.0000000	GO:2000524	GO:BP	negative regulation of T cell costimulation	16175	25827	GO:00026….
query_1	TRUE	0.0014614	3	912	3	0.0032895	1.0000000	GO:0070340	GO:BP	detection of bacterial lipopeptide	16175	16062	GO:00424….
query_1	TRUE	0.0014614	3	912	3	0.0032895	1.0000000	GO:0071663	GO:BP	positive regulation of granzyme B production	16175	16840	GO:00027….
query_1	TRUE	0.0014614	3	912	3	0.0032895	1.0000000	GO:0150064	GO:BP	vertebrate eye-specific patterning	16175	20120	GO:00030….
query_1	TRUE	0.0014614	3	912	3	0.0032895	1.0000000	GO:0097026	GO:BP	dendritic cell dendrite assembly	16175	18450	GO:0120031
query_1	TRUE	0.0014614	3	912	3	0.0032895	1.0000000	GO:0043305	GO:BP	negative regulation of mast cell degranulation	16175	10613	GO:00028….
query_1	TRUE	0.0014614	3	912	3	0.0032895	1.0000000	GO:0002322	GO:BP	B cell proliferation involved in immune response	16175	854	GO:00023….
query_1	TRUE	0.0014930	156	912	21	0.0230263	0.1346154	GO:0042063	GO:BP	gliogenesis	16175	9949	GO:0022008
query_1	TRUE	0.0015549	30	912	8	0.0087719	0.2666667	GO:0045429	GO:BP	positive regulation of nitric oxide biosynthetic process	16175	11373	GO:00068….
query_1	TRUE	0.0015567	677	912	61	0.0668860	0.0901034	GO:0030001	GO:BP	metal ion transport	16175	6646	GO:0006812
query_1	TRUE	0.0015626	748	912	66	0.0723684	0.0882353	GO:0006812	GO:BP	monoatomic cation transport	16175	2492	GO:0006811
query_1	TRUE	0.0015628	11	912	5	0.0054825	0.4545455	GO:0035723	GO:BP	interleukin-15-mediated signaling pathway	16175	9193	GO:00192….
query_1	TRUE	0.0015628	11	912	5	0.0054825	0.4545455	GO:0030852	GO:BP	regulation of granulocyte differentiation	16175	6935	GO:00027….
query_1	TRUE	0.0015628	23	912	7	0.0076754	0.3043478	GO:0045671	GO:BP	negative regulation of osteoclast differentiation	16175	11522	GO:00027….
query_1	TRUE	0.0015628	23	912	7	0.0076754	0.3043478	GO:0045954	GO:BP	positive regulation of natural killer cell mediated cytotoxicity	16175	11746	GO:00019….
query_1	TRUE	0.0015628	23	912	7	0.0076754	0.3043478	GO:0032691	GO:BP	negative regulation of interleukin-1 beta production	16175	7737	GO:00326….
query_1	TRUE	0.0015628	11	912	5	0.0054825	0.4545455	GO:0071350	GO:BP	cellular response to interleukin-15	16175	16602	GO:00706….
query_1	TRUE	0.0015628	11	912	5	0.0054825	0.4545455	GO:0001768	GO:BP	establishment of T cell polarity	16175	434	GO:00017….
query_1	TRUE	0.0015628	11	912	5	0.0054825	0.4545455	GO:0002679	GO:BP	respiratory burst involved in defense response	16175	1197	GO:00022….
query_1	TRUE	0.0015628	11	912	5	0.0054825	0.4545455	GO:0046007	GO:BP	negative regulation of activated T cell proliferation	16175	11798	GO:00421….
query_1	TRUE	0.0015628	11	912	5	0.0054825	0.4545455	GO:0034135	GO:BP	regulation of toll-like receptor 2 signaling pathway	16175	8443	GO:00341….
query_1	TRUE	0.0015628	11	912	5	0.0054825	0.4545455	GO:0001782	GO:BP	B cell homeostasis	16175	447	GO:0002260
query_1	TRUE	0.0015628	11	912	5	0.0054825	0.4545455	GO:0070234	GO:BP	positive regulation of T cell apoptotic process	16175	16004	GO:00702….
query_1	TRUE	0.0015628	11	912	5	0.0054825	0.4545455	GO:0070672	GO:BP	response to interleukin-15	16175	16253	GO:0034097
query_1	TRUE	0.0015628	23	912	7	0.0076754	0.3043478	GO:2000108	GO:BP	positive regulation of leukocyte apoptotic process	16175	25459	GO:00430….
query_1	TRUE	0.0015995	124	912	18	0.0197368	0.1451613	GO:0043405	GO:BP	regulation of MAP kinase activity	16175	10673	GO:0071900
query_1	TRUE	0.0016094	103	912	16	0.0175439	0.1553398	GO:0052547	GO:BP	regulation of peptidase activity	16175	14133	GO:00301….
query_1	TRUE	0.0016300	38	912	9	0.0098684	0.2368421	GO:0002347	GO:BP	response to tumor cell	16175	879	GO:0009607
query_1	TRUE	0.0017997	104	912	16	0.0175439	0.1538462	GO:0009612	GO:BP	response to mechanical stimulus	16175	3540	GO:00096….
query_1	TRUE	0.0018005	74	912	13	0.0142544	0.1756757	GO:0050848	GO:BP	regulation of calcium-mediated signaling	16175	13296	GO:00197….
query_1	TRUE	0.0018032	17	912	6	0.0065789	0.3529412	GO:0055003	GO:BP	cardiac myofibril assembly	16175	14192	GO:00302….
query_1	TRUE	0.0018032	17	912	6	0.0065789	0.3529412	GO:0071353	GO:BP	cellular response to interleukin-4	16175	16605	GO:00706….
query_1	TRUE	0.0018032	17	912	6	0.0065789	0.3529412	GO:0032717	GO:BP	negative regulation of interleukin-8 production	16175	7762	GO:00018….
query_1	TRUE	0.0018032	17	912	6	0.0065789	0.3529412	GO:0150146	GO:BP	cell junction disassembly	16175	20166	GO:00224….
query_1	TRUE	0.0018399	434	912	43	0.0471491	0.0990783	GO:0045596	GO:BP	negative regulation of cell differentiation	16175	11447	GO:00301….
query_1	TRUE	0.0018407	94	912	15	0.0164474	0.1595745	GO:1903531	GO:BP	negative regulation of secretion by cell	16175	23081	GO:00329….
query_1	TRUE	0.0018666	47	912	10	0.0109649	0.2127660	GO:0046596	GO:BP	regulation of viral entry into host cell	16175	12246	GO:00467….
query_1	TRUE	0.0019137	31	912	8	0.0087719	0.2580645	GO:0002230	GO:BP	positive regulation of defense response to virus by host	16175	763	GO:0050691
query_1	TRUE	0.0019137	31	912	8	0.0087719	0.2580645	GO:1904407	GO:BP	positive regulation of nitric oxide metabolic process	16175	23791	GO:00098….
query_1	TRUE	0.0019137	31	912	8	0.0087719	0.2580645	GO:0070231	GO:BP	T cell apoptotic process	16175	16001	GO:0070227
query_1	TRUE	0.0019526	422	912	42	0.0460526	0.0995261	GO:0030003	GO:BP	intracellular monoatomic cation homeostasis	16175	6648	GO:00068….
query_1	TRUE	0.0020495	504	912	48	0.0526316	0.0952381	GO:0001944	GO:BP	vasculature development	16175	555	GO:00487….
query_1	TRUE	0.0020495	24	912	7	0.0076754	0.2916667	GO:0030851	GO:BP	granulocyte differentiation	16175	6934	GO:0002573
query_1	TRUE	0.0022263	307	912	33	0.0361842	0.1074919	GO:0051051	GO:BP	negative regulation of transport	16175	13461	GO:00068….
query_1	TRUE	0.0023027	96	912	15	0.0164474	0.1562500	GO:0032989	GO:BP	cellular anatomical entity morphogenesis	16175	7969	GO:0016043
query_1	TRUE	0.0023027	96	912	15	0.0164474	0.1562500	GO:0010927	GO:BP	cellular component assembly involved in morphogenesis	16175	4511	GO:00226….
query_1	TRUE	0.0023158	646	912	58	0.0635965	0.0897833	GO:0140352	GO:BP	export from cell	16175	19748	GO:00068….
query_1	TRUE	0.0023158	7	912	4	0.0043860	0.5714286	GO:0001660	GO:BP	fever generation	16175	374	GO:00069….
query_1	TRUE	0.0023158	7	912	4	0.0043860	0.5714286	GO:0002291	GO:BP	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	16175	823	GO:0002286
query_1	TRUE	0.0023158	7	912	4	0.0043860	0.5714286	GO:0031666	GO:BP	positive regulation of lipopolysaccharide-mediated signaling pathway	16175	7270	GO:00028….
query_1	TRUE	0.0023158	128	912	18	0.0197368	0.1406250	GO:0034767	GO:BP	positive regulation of monoatomic ion transmembrane transport	16175	8736	GO:00342….
query_1	TRUE	0.0023158	7	912	4	0.0043860	0.5714286	GO:0021561	GO:BP	facial nerve development	16175	6145	GO:00215….
query_1	TRUE	0.0023158	7	912	4	0.0043860	0.5714286	GO:0002727	GO:BP	regulation of natural killer cell cytokine production	16175	1245	GO:00023….
query_1	TRUE	0.0023158	7	912	4	0.0043860	0.5714286	GO:2001280	GO:BP	positive regulation of unsaturated fatty acid biosynthetic process	16175	26457	GO:00066….
query_1	TRUE	0.0023158	7	912	4	0.0043860	0.5714286	GO:0031392	GO:BP	regulation of prostaglandin biosynthetic process	16175	7149	GO:00015….
query_1	TRUE	0.0023158	7	912	4	0.0043860	0.5714286	GO:0031620	GO:BP	regulation of fever generation	16175	7237	GO:00016….
query_1	TRUE	0.0023158	7	912	4	0.0043860	0.5714286	GO:0031652	GO:BP	positive regulation of heat generation	16175	7262	GO:00316….
query_1	TRUE	0.0023158	7	912	4	0.0043860	0.5714286	GO:1904139	GO:BP	regulation of microglial cell migration	16175	23561	GO:19039….
query_1	TRUE	0.0023158	7	912	4	0.0043860	0.5714286	GO:1904124	GO:BP	microglial cell migration	16175	23546	GO:00083….
query_1	TRUE	0.0023158	7	912	4	0.0043860	0.5714286	GO:0070339	GO:BP	response to bacterial lipopeptide	16175	16061	GO:0032493
query_1	TRUE	0.0023158	7	912	4	0.0043860	0.5714286	GO:0071221	GO:BP	cellular response to bacterial lipopeptide	16175	16483	GO:00703….
query_1	TRUE	0.0023158	7	912	4	0.0043860	0.5714286	GO:0071220	GO:BP	cellular response to bacterial lipoprotein	16175	16482	GO:00324….
query_1	TRUE	0.0023158	7	912	4	0.0043860	0.5714286	GO:0002370	GO:BP	natural killer cell cytokine production	16175	902	GO:00022….
query_1	TRUE	0.0023158	7	912	4	0.0043860	0.5714286	GO:0030240	GO:BP	skeletal muscle thin filament assembly	16175	6737	GO:00070….
query_1	TRUE	0.0023158	7	912	4	0.0043860	0.5714286	GO:0021610	GO:BP	facial nerve morphogenesis	16175	6193	GO:00215….
query_1	TRUE	0.0023158	426	912	42	0.0460526	0.0985915	GO:0006873	GO:BP	intracellular monoatomic ion homeostasis	16175	2531	GO:00508….
query_1	TRUE	0.0023158	7	912	4	0.0043860	0.5714286	GO:0002729	GO:BP	positive regulation of natural killer cell cytokine production	16175	1247	GO:00023….
query_1	TRUE	0.0023158	7	912	4	0.0043860	0.5714286	GO:0021612	GO:BP	facial nerve structural organization	16175	6195	GO:00216….
query_1	TRUE	0.0023366	32	912	8	0.0087719	0.2500000	GO:1904646	GO:BP	cellular response to amyloid-beta	16175	23986	GO:19016….
query_1	TRUE	0.0023366	32	912	8	0.0087719	0.2500000	GO:1905521	GO:BP	regulation of macrophage migration	16175	24697	GO:00716….
query_1	TRUE	0.0023860	12	912	5	0.0054825	0.4166667	GO:0071605	GO:BP	monocyte chemotactic protein-1 production	16175	16791	GO:0032602
query_1	TRUE	0.0023860	12	912	5	0.0054825	0.4166667	GO:0046851	GO:BP	negative regulation of bone remodeling	16175	12403	GO:00341….
query_1	TRUE	0.0023860	12	912	5	0.0054825	0.4166667	GO:0071637	GO:BP	regulation of monocyte chemotactic protein-1 production	16175	16814	GO:00326….
query_1	TRUE	0.0023860	12	912	5	0.0054825	0.4166667	GO:0001767	GO:BP	establishment of lymphocyte polarity	16175	433	GO:00300….
query_1	TRUE	0.0023860	12	912	5	0.0054825	0.4166667	GO:0034695	GO:BP	response to prostaglandin E	16175	8717	GO:00346….
query_1	TRUE	0.0023860	12	912	5	0.0054825	0.4166667	GO:0021559	GO:BP	trigeminal nerve development	16175	6143	GO:0021545
query_1	TRUE	0.0023860	12	912	5	0.0054825	0.4166667	GO:1905153	GO:BP	regulation of membrane invagination	16175	24401	GO:00103….
query_1	TRUE	0.0023860	12	912	5	0.0054825	0.4166667	GO:0060099	GO:BP	regulation of phagocytosis, engulfment	16175	14355	GO:00069….
query_1	TRUE	0.0023860	12	912	5	0.0054825	0.4166667	GO:0016554	GO:BP	cytidine to uridine editing	16175	5245	GO:0016553
query_1	TRUE	0.0024226	18	912	6	0.0065789	0.3333333	GO:0070670	GO:BP	response to interleukin-4	16175	16251	GO:0034097
query_1	TRUE	0.0024226	18	912	6	0.0065789	0.3333333	GO:0033630	GO:BP	positive regulation of cell adhesion mediated by integrin	16175	8331	GO:00336….
query_1	TRUE	0.0024226	18	912	6	0.0065789	0.3333333	GO:0046641	GO:BP	positive regulation of alpha-beta T cell proliferation	16175	12278	GO:00421….
query_1	TRUE	0.0024226	18	912	6	0.0065789	0.3333333	GO:0045091	GO:BP	regulation of single stranded viral RNA replication via double stranded DNA intermediate	16175	11273	GO:00396….
query_1	TRUE	0.0024490	284	912	31	0.0339912	0.1091549	GO:0010959	GO:BP	regulation of metal ion transport	16175	4536	GO:00300….
query_1	TRUE	0.0025154	49	912	10	0.0109649	0.2040816	GO:0046456	GO:BP	icosanoid biosynthetic process	16175	12164	GO:00066….
query_1	TRUE	0.0025154	49	912	10	0.0109649	0.2040816	GO:0072577	GO:BP	endothelial cell apoptotic process	16175	17450	GO:0006915
query_1	TRUE	0.0025340	272	912	30	0.0328947	0.1102941	GO:0050673	GO:BP	epithelial cell proliferation	16175	13207	GO:0008283
query_1	TRUE	0.0026289	999	912	82	0.0899123	0.0820821	GO:0051247	GO:BP	positive regulation of protein metabolic process	16175	13594	GO:00106….
query_1	TRUE	0.0026486	141	912	19	0.0208333	0.1347518	GO:0050679	GO:BP	positive regulation of epithelial cell proliferation	16175	13213	GO:00082….
query_1	TRUE	0.0026633	119	912	17	0.0186404	0.1428571	GO:0019079	GO:BP	viral genome replication	16175	5569	GO:00160….
query_1	TRUE	0.0027644	512	912	48	0.0526316	0.0937500	GO:0051338	GO:BP	regulation of transferase activity	16175	13665	GO:0050790
query_1	TRUE	0.0027767	41	912	9	0.0098684	0.2195122	GO:1904645	GO:BP	response to amyloid-beta	16175	23985	GO:19016….
query_1	TRUE	0.0028387	33	912	8	0.0087719	0.2424242	GO:1900225	GO:BP	regulation of NLRP3 inflammasome complex assembly	16175	20497	GO:00432….
query_1	TRUE	0.0028387	33	912	8	0.0087719	0.2424242	GO:0034110	GO:BP	regulation of homotypic cell-cell adhesion	16175	8418	GO:00224….
query_1	TRUE	0.0028387	33	912	8	0.0087719	0.2424242	GO:0046006	GO:BP	regulation of activated T cell proliferation	16175	11797	GO:00421….
query_1	TRUE	0.0028387	78	912	13	0.0142544	0.1666667	GO:0061844	GO:BP	antimicrobial humoral immune response mediated by antimicrobial peptide	16175	15685	GO:0019730
query_1	TRUE	0.0028387	274	912	30	0.0328947	0.1094891	GO:0051235	GO:BP	maintenance of location	16175	13585	GO:0051179
query_1	TRUE	0.0030132	275	912	30	0.0328947	0.1090909	GO:2001233	GO:BP	regulation of apoptotic signaling pathway	16175	26422	GO:00099….
query_1	TRUE	0.0030310	250	912	28	0.0307018	0.1120000	GO:0042692	GO:BP	muscle cell differentiation	16175	10302	GO:00301….
query_1	TRUE	0.0031007	301	912	32	0.0350877	0.1063123	GO:0051347	GO:BP	positive regulation of transferase activity	16175	13674	GO:00430….
query_1	TRUE	0.0031914	132	912	18	0.0197368	0.1363636	GO:1903034	GO:BP	regulation of response to wounding	16175	22714	GO:00096….
query_1	TRUE	0.0032003	79	912	13	0.0142544	0.1645570	GO:0045639	GO:BP	positive regulation of myeloid cell differentiation	16175	11490	GO:00300….
query_1	TRUE	0.0032455	407	912	40	0.0438596	0.0982801	GO:0098771	GO:BP	inorganic ion homeostasis	16175	18886	GO:0048878
query_1	TRUE	0.0032727	26	912	7	0.0076754	0.2692308	GO:0008347	GO:BP	glial cell migration	16175	3172	GO:00164….
query_1	TRUE	0.0032809	19	912	6	0.0065789	0.3157895	GO:0039692	GO:BP	single stranded viral RNA replication via double stranded DNA intermediate	16175	9869	GO:0039694
query_1	TRUE	0.0032809	19	912	6	0.0065789	0.3157895	GO:0043304	GO:BP	regulation of mast cell degranulation	16175	10612	GO:00028….
query_1	TRUE	0.0032998	42	912	9	0.0098684	0.2142857	GO:1905517	GO:BP	macrophage migration	16175	24693	GO:00716….
query_1	TRUE	0.0033435	60	912	11	0.0120614	0.1833333	GO:0043903	GO:BP	regulation of biological process involved in symbiotic interaction	16175	10855	GO:00444….
query_1	TRUE	0.0034210	744	912	64	0.0701754	0.0860215	GO:0072359	GO:BP	circulatory system development	16175	17370	GO:0048731
query_1	TRUE	0.0034616	111	912	16	0.0175439	0.1441441	GO:0008037	GO:BP	cell recognition	16175	3099	GO:0009987
query_1	TRUE	0.0034684	34	912	8	0.0087719	0.2352941	GO:2001238	GO:BP	positive regulation of extrinsic apoptotic signaling pathway	16175	26427	GO:00971….
query_1	TRUE	0.0034684	34	912	8	0.0087719	0.2352941	GO:0042554	GO:BP	superoxide anion generation	16175	10244	GO:0006801
query_1	TRUE	0.0034982	90	912	14	0.0153509	0.1555556	GO:2001235	GO:BP	positive regulation of apoptotic signaling pathway	16175	26424	GO:00099….
query_1	TRUE	0.0035252	13	912	5	0.0054825	0.3846154	GO:0071800	GO:BP	podosome assembly	16175	16914	GO:00650….
query_1	TRUE	0.0035252	13	912	5	0.0054825	0.3846154	GO:0070230	GO:BP	positive regulation of lymphocyte apoptotic process	16175	16000	GO:00702….
query_1	TRUE	0.0035252	13	912	5	0.0054825	0.3846154	GO:0034144	GO:BP	negative regulation of toll-like receptor 4 signaling pathway	16175	8452	GO:00026….
query_1	TRUE	0.0035252	13	912	5	0.0054825	0.3846154	GO:0031643	GO:BP	positive regulation of myelination	16175	7253	GO:00316….
query_1	TRUE	0.0035252	13	912	5	0.0054825	0.3846154	GO:0023035	GO:BP	CD40 signaling pathway	16175	6637	GO:0007166
query_1	TRUE	0.0035252	13	912	5	0.0054825	0.3846154	GO:0045006	GO:BP	DNA deamination	16175	11224	GO:0006304
query_1	TRUE	0.0035778	631	912	56	0.0614035	0.0887480	GO:0022603	GO:BP	regulation of anatomical structure morphogenesis	16175	6611	GO:00096….
query_1	TRUE	0.0036778	101	912	15	0.0164474	0.1485149	GO:0007229	GO:BP	integrin-mediated signaling pathway	16175	2779	GO:0007166
query_1	TRUE	0.0038764	217	912	25	0.0274123	0.1152074	GO:0007188	GO:BP	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	16175	2746	GO:0007186
query_1	TRUE	0.0038790	619	912	55	0.0603070	0.0888530	GO:1901698	GO:BP	response to nitrogen compound	16175	21651	GO:0042221
query_1	TRUE	0.0039515	193	912	23	0.0252193	0.1191710	GO:0098742	GO:BP	cell-cell adhesion via plasma-membrane adhesion molecules	16175	18867	GO:0098609
query_1	TRUE	0.0039621	52	912	10	0.0109649	0.1923077	GO:0046849	GO:BP	bone remodeling	16175	12401	GO:0048771
query_1	TRUE	0.0039621	52	912	10	0.0109649	0.1923077	GO:0007157	GO:BP	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	16175	2721	GO:0098742
query_1	TRUE	0.0039779	71	912	12	0.0131579	0.1690141	GO:0045638	GO:BP	negative regulation of myeloid cell differentiation	16175	11489	GO:00300….
query_1	TRUE	0.0039873	480	912	45	0.0493421	0.0937500	GO:0001568	GO:BP	blood vessel development	16175	353	GO:00019….
query_1	TRUE	0.0040481	8	912	4	0.0043860	0.5000000	GO:0031650	GO:BP	regulation of heat generation	16175	7260	GO:00316….
query_1	TRUE	0.0040481	8	912	4	0.0043860	0.5000000	GO:0021604	GO:BP	cranial nerve structural organization	16175	6187	GO:00216….
query_1	TRUE	0.0040481	8	912	4	0.0043860	0.5000000	GO:0045059	GO:BP	positive thymic T cell selection	16175	11257	GO:00433….
query_1	TRUE	0.0040481	8	912	4	0.0043860	0.5000000	GO:0032493	GO:BP	response to bacterial lipoprotein	16175	7604	GO:0002237
query_1	TRUE	0.0040481	8	912	4	0.0043860	0.5000000	GO:0043376	GO:BP	regulation of CD8-positive, alpha-beta T cell differentiation	16175	10653	GO:00433….
query_1	TRUE	0.0040481	8	912	4	0.0043860	0.5000000	GO:0002578	GO:BP	negative regulation of antigen processing and presentation	16175	1099	GO:00025….
query_1	TRUE	0.0040481	102	912	15	0.0164474	0.1470588	GO:0008360	GO:BP	regulation of cell shape	16175	3179	GO:00226….
query_1	TRUE	0.0040481	27	912	7	0.0076754	0.2592593	GO:0021545	GO:BP	cranial nerve development	16175	6129	GO:0021675
query_1	TRUE	0.0040481	8	912	4	0.0043860	0.5000000	GO:1903977	GO:BP	positive regulation of glial cell migration	16175	23434	GO:00083….
query_1	TRUE	0.0040481	8	912	4	0.0043860	0.5000000	GO:0002767	GO:BP	immune response-inhibiting cell surface receptor signaling pathway	16175	1278	GO:00027….
query_1	TRUE	0.0040481	8	912	4	0.0043860	0.5000000	GO:2000510	GO:BP	positive regulation of dendritic cell chemotaxis	16175	25813	GO:00024….
query_1	TRUE	0.0040481	27	912	7	0.0076754	0.2592593	GO:0032692	GO:BP	negative regulation of interleukin-1 production	16175	7738	GO:00018….
query_1	TRUE	0.0040481	8	912	4	0.0043860	0.5000000	GO:0031649	GO:BP	heat generation	16175	7259	GO:0001659
query_1	TRUE	0.0040481	8	912	4	0.0043860	0.5000000	GO:2000427	GO:BP	positive regulation of apoptotic cell clearance	16175	25742	GO:00432….
query_1	TRUE	0.0040481	8	912	4	0.0043860	0.5000000	GO:0097527	GO:BP	necroptotic signaling pathway	16175	18687	GO:00071….
query_1	TRUE	0.0041124	170	912	21	0.0230263	0.1235294	GO:0097191	GO:BP	extrinsic apoptotic signaling pathway	16175	18535	GO:00071….
query_1	TRUE	0.0042339	92	912	14	0.0153509	0.1521739	GO:0016525	GO:BP	negative regulation of angiogenesis	16175	5237	GO:00015….
query_1	TRUE	0.0042534	20	912	6	0.0065789	0.3000000	GO:0030277	GO:BP	maintenance of gastrointestinal epithelium	16175	6754	GO:00106….
query_1	TRUE	0.0042534	20	912	6	0.0065789	0.3000000	GO:0141087	GO:BP	positive regulation of inflammasome-mediated signaling pathway	16175	20018	GO:00622….
query_1	TRUE	0.0042534	20	912	6	0.0065789	0.3000000	GO:0002675	GO:BP	positive regulation of acute inflammatory response	16175	1193	GO:00025….
query_1	TRUE	0.0044692	114	912	16	0.0175439	0.1403509	GO:1904064	GO:BP	positive regulation of cation transmembrane transport	16175	23503	GO:00347….
query_1	TRUE	0.0044750	442	912	42	0.0460526	0.0950226	GO:0051046	GO:BP	regulation of secretion	16175	13456	GO:00469….
query_1	TRUE	0.0045000	53	912	10	0.0109649	0.1886792	GO:0034142	GO:BP	toll-like receptor 4 signaling pathway	16175	8450	GO:0140895
query_1	TRUE	0.0045000	44	912	9	0.0098684	0.2045455	GO:0045428	GO:BP	regulation of nitric oxide biosynthetic process	16175	11372	GO:00068….
query_1	TRUE	0.0045000	44	912	9	0.0098684	0.2045455	GO:0048260	GO:BP	positive regulation of receptor-mediated endocytosis	16175	12612	GO:00068….
query_1	TRUE	0.0045309	148	912	19	0.0208333	0.1283784	GO:0017157	GO:BP	regulation of exocytosis	16175	5287	GO:00068….
query_1	TRUE	0.0046247	4	912	3	0.0032895	0.7500000	GO:0002282	GO:BP	microglial cell activation involved in immune response	16175	814	GO:00017….
query_1	TRUE	0.0046247	4	912	3	0.0032895	0.7500000	GO:0061044	GO:BP	negative regulation of vascular wound healing	16175	15160	GO:00165….
query_1	TRUE	0.0046247	4	912	3	0.0032895	0.7500000	GO:0002666	GO:BP	positive regulation of T cell tolerance induction	16175	1184	GO:00025….
query_1	TRUE	0.0046247	4	912	3	0.0032895	0.7500000	GO:0043615	GO:BP	astrocyte cell migration	16175	10806	GO:0008347
query_1	TRUE	0.0046247	4	912	3	0.0032895	0.7500000	GO:0034124	GO:BP	regulation of MyD88-dependent toll-like receptor signaling pathway	16175	8432	GO:00027….
query_1	TRUE	0.0046247	4	912	3	0.0032895	0.7500000	GO:0002774	GO:BP	Fc receptor mediated inhibitory signaling pathway	16175	1285	GO:0002767
query_1	TRUE	0.0046247	4	912	3	0.0032895	0.7500000	GO:1904151	GO:BP	positive regulation of microglial cell mediated cytotoxicity	16175	23572	GO:00019….
query_1	TRUE	0.0046247	4	912	3	0.0032895	0.7500000	GO:1904997	GO:BP	regulation of leukocyte adhesion to arterial endothelial cell	16175	24282	GO:00617….
query_1	TRUE	0.0046247	4	912	3	0.0032895	0.7500000	GO:0042494	GO:BP	detection of bacterial lipoprotein	16175	10222	GO:00160….
query_1	TRUE	0.0046247	4	912	3	0.0032895	0.7500000	GO:2000348	GO:BP	regulation of CD40 signaling pathway	16175	25667	GO:00099….
query_1	TRUE	0.0046261	93	912	14	0.0153509	0.1505376	GO:2000181	GO:BP	negative regulation of blood vessel morphogenesis	16175	25513	GO:00226….
query_1	TRUE	0.0048193	63	912	11	0.0120614	0.1746032	GO:0061045	GO:BP	negative regulation of wound healing	16175	15161	GO:00321….
query_1	TRUE	0.0049068	36	912	8	0.0087719	0.2222222	GO:0046850	GO:BP	regulation of bone remodeling	16175	12402	GO:00341….
query_1	TRUE	0.0049068	36	912	8	0.0087719	0.2222222	GO:1900744	GO:BP	regulation of p38MAPK cascade	16175	20916	GO:00380….
query_1	TRUE	0.0049094	14	912	5	0.0054825	0.3571429	GO:0010935	GO:BP	regulation of macrophage cytokine production	16175	4519	GO:00027….
query_1	TRUE	0.0049094	14	912	5	0.0054825	0.3571429	GO:0010934	GO:BP	macrophage cytokine production	16175	4518	GO:0061082
query_1	TRUE	0.0049094	14	912	5	0.0054825	0.3571429	GO:0072567	GO:BP	chemokine (C-X-C motif) ligand 2 production	16175	17445	GO:0032602
query_1	TRUE	0.0049094	14	912	5	0.0054825	0.3571429	GO:0034104	GO:BP	negative regulation of tissue remodeling	16175	8412	GO:00341….
query_1	TRUE	0.0049094	14	912	5	0.0054825	0.3571429	GO:0002523	GO:BP	leukocyte migration involved in inflammatory response	16175	1045	GO:00069….
query_1	TRUE	0.0049094	14	912	5	0.0054825	0.3571429	GO:0150079	GO:BP	negative regulation of neuroinflammatory response	16175	20131	GO:00507….
query_1	TRUE	0.0049094	14	912	5	0.0054825	0.3571429	GO:2000341	GO:BP	regulation of chemokine (C-X-C motif) ligand 2 production	16175	25660	GO:00326….
query_1	TRUE	0.0049165	28	912	7	0.0076754	0.2500000	GO:0034143	GO:BP	regulation of toll-like receptor 4 signaling pathway	16175	8451	GO:00341….
query_1	TRUE	0.0049952	173	912	21	0.0230263	0.1213873	GO:0031334	GO:BP	positive regulation of protein-containing complex assembly	16175	7125	GO:00432….
query_1	TRUE	0.0050829	54	912	10	0.0109649	0.1851852	GO:0002312	GO:BP	B cell activation involved in immune response	16175	844	GO:00022….
query_1	TRUE	0.0050829	54	912	10	0.0109649	0.1851852	GO:0052372	GO:BP	modulation by symbiont of entry into host	16175	14118	GO:00439….
query_1	TRUE	0.0050829	94	912	14	0.0153509	0.1489362	GO:1901343	GO:BP	negative regulation of vasculature development	16175	21402	GO:00019….
query_1	TRUE	0.0050829	54	912	10	0.0109649	0.1851852	GO:0031638	GO:BP	zymogen activation	16175	7248	GO:0016485
query_1	TRUE	0.0050829	54	912	10	0.0109649	0.1851852	GO:0050688	GO:BP	regulation of defense response to virus	16175	13219	GO:00028….
query_1	TRUE	0.0051587	45	912	9	0.0098684	0.2000000	GO:0038066	GO:BP	p38MAPK cascade	16175	9683	GO:0000165
query_1	TRUE	0.0051587	45	912	9	0.0098684	0.2000000	GO:0002637	GO:BP	regulation of immunoglobulin production	16175	1158	GO:00023….
query_1	TRUE	0.0051587	45	912	9	0.0098684	0.2000000	GO:0002763	GO:BP	positive regulation of myeloid leukocyte differentiation	16175	1274	GO:00025….
query_1	TRUE	0.0053862	447	912	42	0.0460526	0.0939597	GO:0048514	GO:BP	blood vessel morphogenesis	16175	12799	GO:00015….
query_1	TRUE	0.0054165	21	912	6	0.0065789	0.2857143	GO:1900016	GO:BP	negative regulation of cytokine production involved in inflammatory response	16175	20327	GO:00018….
query_1	TRUE	0.0054165	21	912	6	0.0065789	0.2857143	GO:2001056	GO:BP	positive regulation of cysteine-type endopeptidase activity	16175	26298	GO:00109….
query_1	TRUE	0.0054165	967	912	78	0.0855263	0.0806618	GO:0031399	GO:BP	regulation of protein modification process	16175	7155	GO:00362….
query_1	TRUE	0.0054165	21	912	6	0.0065789	0.2857143	GO:0061082	GO:BP	myeloid leukocyte cytokine production	16175	15198	GO:0002367
query_1	TRUE	0.0054712	366	912	36	0.0394737	0.0983607	GO:0051336	GO:BP	regulation of hydrolase activity	16175	13663	GO:0050790
query_1	TRUE	0.0058015	37	912	8	0.0087719	0.2162162	GO:0045453	GO:BP	bone resorption	16175	11383	GO:00018….
query_1	TRUE	0.0058447	140	912	18	0.0197368	0.1285714	GO:0007189	GO:BP	adenylate cyclase-activating G protein-coupled receptor signaling pathway	16175	2747	GO:0007188
query_1	TRUE	0.0060387	46	912	9	0.0098684	0.1956522	GO:0080164	GO:BP	regulation of nitric oxide metabolic process	16175	17838	GO:00192….
query_1	TRUE	0.0060434	29	912	7	0.0076754	0.2413793	GO:0002323	GO:BP	natural killer cell activation involved in immune response	16175	855	GO:00022….
query_1	TRUE	0.0064972	9	912	4	0.0043860	0.4444444	GO:0038110	GO:BP	interleukin-2-mediated signaling pathway	16175	9704	GO:00192….
query_1	TRUE	0.0064972	9	912	4	0.0043860	0.4444444	GO:0071352	GO:BP	cellular response to interleukin-2	16175	16604	GO:00706….
query_1	TRUE	0.0064972	9	912	4	0.0043860	0.4444444	GO:2001279	GO:BP	regulation of unsaturated fatty acid biosynthetic process	16175	26456	GO:00066….
query_1	TRUE	0.0064972	9	912	4	0.0043860	0.4444444	GO:0032621	GO:BP	interleukin-18 production	16175	7668	GO:0001816
query_1	TRUE	0.0064972	9	912	4	0.0043860	0.4444444	GO:0060267	GO:BP	positive regulation of respiratory burst	16175	14484	GO:00098….
query_1	TRUE	0.0064972	9	912	4	0.0043860	0.4444444	GO:0043307	GO:BP	eosinophil activation	16175	10615	GO:0036230
query_1	TRUE	0.0064972	9	912	4	0.0043860	0.4444444	GO:0032661	GO:BP	regulation of interleukin-18 production	16175	7707	GO:00018….
query_1	TRUE	0.0064972	9	912	4	0.0043860	0.4444444	GO:0060907	GO:BP	positive regulation of macrophage cytokine production	16175	15037	GO:00109….
query_1	TRUE	0.0064972	9	912	4	0.0043860	0.4444444	GO:0014866	GO:BP	skeletal myofibril assembly	16175	4743	GO:0030239
query_1	TRUE	0.0064972	2128	912	152	0.1666667	0.0714286	GO:0065008	GO:BP	regulation of biological quality	16175	15891	GO:0065007
query_1	TRUE	0.0064972	9	912	4	0.0043860	0.4444444	GO:0002725	GO:BP	negative regulation of T cell cytokine production	16175	1243	GO:00023….
query_1	TRUE	0.0066497	56	912	10	0.0109649	0.1785714	GO:0034103	GO:BP	regulation of tissue remodeling	16175	8411	GO:00487….
query_1	TRUE	0.0066595	885	912	72	0.0789474	0.0813559	GO:0006811	GO:BP	monoatomic ion transport	16175	2491	GO:0006810
query_1	TRUE	0.0067364	15	912	5	0.0054825	0.3333333	GO:0007252	GO:BP	I-kappaB phosphorylation	16175	2785	GO:00064….
query_1	TRUE	0.0067364	15	912	5	0.0054825	0.3333333	GO:0034694	GO:BP	response to prostaglandin	16175	8716	GO:00097….
query_1	TRUE	0.0067364	15	912	5	0.0054825	0.3333333	GO:1903978	GO:BP	regulation of microglial cell activation	16175	23435	GO:00017….
query_1	TRUE	0.0067364	15	912	5	0.0054825	0.3333333	GO:0002476	GO:BP	antigen processing and presentation of endogenous peptide antigen via MHC class Ib	16175	999	GO:00024….
query_1	TRUE	0.0067364	15	912	5	0.0054825	0.3333333	GO:0033631	GO:BP	cell-cell adhesion mediated by integrin	16175	8332	GO:00336….
query_1	TRUE	0.0067364	15	912	5	0.0054825	0.3333333	GO:0002428	GO:BP	antigen processing and presentation of peptide antigen via MHC class Ib	16175	951	GO:00024….
query_1	TRUE	0.0068075	38	912	8	0.0087719	0.2105263	GO:0033077	GO:BP	T cell differentiation in thymus	16175	8025	GO:0030217
query_1	TRUE	0.0068075	38	912	8	0.0087719	0.2105263	GO:0050832	GO:BP	defense response to fungus	16175	13290	GO:00096….
query_1	TRUE	0.0068075	38	912	8	0.0087719	0.2105263	GO:0002686	GO:BP	negative regulation of leukocyte migration	16175	1204	GO:00026….
query_1	TRUE	0.0068078	66	912	11	0.0120614	0.1666667	GO:0032481	GO:BP	positive regulation of type I interferon production	16175	7592	GO:00018….
query_1	TRUE	0.0068078	467	912	43	0.0471491	0.0920771	GO:0055080	GO:BP	monoatomic cation homeostasis	16175	14233	GO:0050801
query_1	TRUE	0.0068732	22	912	6	0.0065789	0.2727273	GO:0070232	GO:BP	regulation of T cell apoptotic process	16175	16002	GO:00702….
query_1	TRUE	0.0074781	414	912	39	0.0427632	0.0942029	GO:0061061	GO:BP	muscle structure development	16175	15177	GO:0048856
query_1	TRUE	0.0075404	77	912	12	0.0131579	0.1558442	GO:0032088	GO:BP	negative regulation of NF-kappaB transcription factor activity	16175	7355	GO:0043433
query_1	TRUE	0.0075404	77	912	12	0.0131579	0.1558442	GO:0043406	GO:BP	positive regulation of MAP kinase activity	16175	10674	GO:00434….
query_1	TRUE	0.0084462	78	912	12	0.0131579	0.1538462	GO:1903035	GO:BP	negative regulation of response to wounding	16175	22715	GO:00096….
query_1	TRUE	0.0084462	78	912	12	0.0131579	0.1538462	GO:0046330	GO:BP	positive regulation of JNK cascade	16175	12063	GO:00072….
query_1	TRUE	0.0087868	23	912	6	0.0065789	0.2608696	GO:0035458	GO:BP	cellular response to interferon-beta	16175	9046	GO:00354….
query_1	TRUE	0.0087868	23	912	6	0.0065789	0.2608696	GO:0034114	GO:BP	regulation of heterotypic cell-cell adhesion	16175	8422	GO:00224….
query_1	TRUE	0.0087868	23	912	6	0.0065789	0.2608696	GO:0002418	GO:BP	immune response to tumor cell	16175	942	GO:00023….
query_1	TRUE	0.0090382	881	912	71	0.0778509	0.0805902	GO:0051130	GO:BP	positive regulation of cellular component organization	16175	13514	GO:00160….
query_1	TRUE	0.0091640	16	912	5	0.0054825	0.3125000	GO:0070207	GO:BP	protein homotrimerization	16175	15988	GO:00512….
query_1	TRUE	0.0091640	16	912	5	0.0054825	0.3125000	GO:0070206	GO:BP	protein trimerization	16175	15987	GO:0051259
query_1	TRUE	0.0091640	16	912	5	0.0054825	0.3125000	GO:0061081	GO:BP	positive regulation of myeloid leukocyte cytokine production involved in immune response	16175	15197	GO:00027….
query_1	TRUE	0.0091640	16	912	5	0.0054825	0.3125000	GO:0043371	GO:BP	negative regulation of CD4-positive, alpha-beta T cell differentiation	16175	10648	GO:00433….
query_1	TRUE	0.0093343	475	912	43	0.0471491	0.0905263	GO:0050801	GO:BP	monoatomic ion homeostasis	16175	13267	GO:0048878
query_1	TRUE	0.0097503	69	912	11	0.0120614	0.1594203	GO:1904427	GO:BP	positive regulation of calcium ion transmembrane transport	16175	23809	GO:00519….
query_1	TRUE	0.0097732	59	912	10	0.0109649	0.1694915	GO:0002062	GO:BP	chondrocyte differentiation	16175	653	GO:00301….
query_1	TRUE	0.0099263	10	912	4	0.0043860	0.4000000	GO:0045779	GO:BP	negative regulation of bone resorption	16175	11613	GO:00451….
query_1	TRUE	0.0099263	10	912	4	0.0043860	0.4000000	GO:0051770	GO:BP	positive regulation of nitric-oxide synthase biosynthetic process	16175	13926	GO:00105….
query_1	TRUE	0.0099263	10	912	4	0.0043860	0.4000000	GO:0033632	GO:BP	regulation of cell-cell adhesion mediated by integrin	16175	8333	GO:00224….
query_1	TRUE	0.0099263	10	912	4	0.0043860	0.4000000	GO:0061043	GO:BP	regulation of vascular wound healing	16175	15159	GO:00457….
query_1	TRUE	0.0099263	10	912	4	0.0043860	0.4000000	GO:0070669	GO:BP	response to interleukin-2	16175	16250	GO:0034097
query_1	TRUE	0.0099263	10	912	4	0.0043860	0.4000000	GO:0021783	GO:BP	preganglionic parasympathetic fiber development	16175	6361	GO:00074….
query_1	TRUE	0.0099263	10	912	4	0.0043860	0.4000000	GO:1905155	GO:BP	positive regulation of membrane invagination	16175	24403	GO:00103….
query_1	TRUE	0.0099263	10	912	4	0.0043860	0.4000000	GO:0035590	GO:BP	purinergic nucleotide receptor signaling pathway	16175	9107	GO:0007166
query_1	TRUE	0.0099263	10	912	4	0.0043860	0.4000000	GO:0090103	GO:BP	cochlea morphogenesis	16175	18021	GO:00424….
query_1	TRUE	0.0099263	10	912	4	0.0043860	0.4000000	GO:0060100	GO:BP	positive regulation of phagocytosis, engulfment	16175	14356	GO:00069….
query_1	TRUE	0.0100405	5	912	3	0.0032895	0.6000000	GO:0043313	GO:BP	regulation of neutrophil degranulation	16175	10621	GO:00028….
query_1	TRUE	0.0100405	5	912	3	0.0032895	0.6000000	GO:0070487	GO:BP	monocyte aggregation	16175	16148	GO:0070486
query_1	TRUE	0.0100405	5	912	3	0.0032895	0.6000000	GO:0048003	GO:BP	antigen processing and presentation of lipid antigen via MHC class Ib	16175	12461	GO:0002475
query_1	TRUE	0.0100405	5	912	3	0.0032895	0.6000000	GO:0002638	GO:BP	negative regulation of immunoglobulin production	16175	1159	GO:00023….
query_1	TRUE	0.0100405	5	912	3	0.0032895	0.6000000	GO:0038159	GO:BP	C-X-C chemokine receptor CXCR4 signaling pathway	16175	9738	GO:0070098
query_1	TRUE	0.0100405	5	912	3	0.0032895	0.6000000	GO:0046643	GO:BP	regulation of gamma-delta T cell activation	16175	12280	GO:00466….
query_1	TRUE	0.0100405	5	912	3	0.0032895	0.6000000	GO:0061757	GO:BP	leukocyte adhesion to arterial endothelial cell	16175	15651	GO:0061756
query_1	TRUE	0.0100405	5	912	3	0.0032895	0.6000000	GO:0140639	GO:BP	positive regulation of pyroptotic inflammatory response	16175	19843	GO:00507….
query_1	TRUE	0.0100405	5	912	3	0.0032895	0.6000000	GO:0048006	GO:BP	antigen processing and presentation, endogenous lipid antigen via MHC class Ib	16175	12462	GO:00198….
query_1	TRUE	0.0100405	5	912	3	0.0032895	0.6000000	GO:0045590	GO:BP	negative regulation of regulatory T cell differentiation	16175	11441	GO:00450….
query_1	TRUE	0.0100405	5	912	3	0.0032895	0.6000000	GO:0048007	GO:BP	antigen processing and presentation, exogenous lipid antigen via MHC class Ib	16175	12463	GO:00198….
query_1	TRUE	0.0102196	80	912	12	0.0131579	0.1500000	GO:0030278	GO:BP	regulation of ossification	16175	6755	GO:00015….
query_1	TRUE	0.0102941	113	912	15	0.0164474	0.1327434	GO:2001236	GO:BP	regulation of extrinsic apoptotic signaling pathway	16175	26425	GO:00971….
query_1	TRUE	0.0104822	50	912	9	0.0098684	0.1800000	GO:0001706	GO:BP	endoderm formation	16175	398	GO:00017….
query_1	TRUE	0.0104907	32	912	7	0.0076754	0.2187500	GO:0002920	GO:BP	regulation of humoral immune response	16175	1430	GO:00069….
query_1	TRUE	0.0104907	91	912	13	0.0142544	0.1428571	GO:0051346	GO:BP	negative regulation of hydrolase activity	16175	13673	GO:00430….
query_1	TRUE	0.0107623	24	912	6	0.0065789	0.2500000	GO:0006953	GO:BP	acute-phase response	16175	2584	GO:0002526
query_1	TRUE	0.0107623	24	912	6	0.0065789	0.2500000	GO:0090382	GO:BP	phagosome maturation	16175	18256	GO:0006996
query_1	TRUE	0.0108247	60	912	10	0.0109649	0.1666667	GO:0002244	GO:BP	hematopoietic progenitor cell differentiation	16175	777	GO:00300….
query_1	TRUE	0.0108937	41	912	8	0.0087719	0.1951220	GO:0140894	GO:BP	endolysosomal toll-like receptor signaling pathway	16175	19926	GO:0002753
query_1	TRUE	0.0115325	92	912	13	0.0142544	0.1413043	GO:0048771	GO:BP	tissue remodeling	16175	13020	GO:0032501
query_1	TRUE	0.0119422	17	912	5	0.0054825	0.2941176	GO:0032682	GO:BP	negative regulation of chemokine production	16175	7728	GO:00018….
query_1	TRUE	0.0119422	71	912	11	0.0120614	0.1549296	GO:0060761	GO:BP	negative regulation of response to cytokine stimulus	16175	14929	GO:00340….
query_1	TRUE	0.0119717	51	912	9	0.0098684	0.1764706	GO:0032648	GO:BP	regulation of interferon-beta production	16175	7695	GO:00324….
query_1	TRUE	0.0119717	51	912	9	0.0098684	0.1764706	GO:0032608	GO:BP	interferon-beta production	16175	7656	GO:0032606
query_1	TRUE	0.0124692	358	912	34	0.0372807	0.0949721	GO:0008015	GO:BP	blood circulation	16175	3096	GO:0003013
query_1	TRUE	0.0125390	33	912	7	0.0076754	0.2121212	GO:0002673	GO:BP	regulation of acute inflammatory response	16175	1191	GO:00025….
query_1	TRUE	0.0127023	42	912	8	0.0087719	0.1904762	GO:0010466	GO:BP	negative regulation of peptidase activity	16175	4159	GO:00458….
query_1	TRUE	0.0131778	116	912	15	0.0164474	0.1293103	GO:0030832	GO:BP	regulation of actin filament length	16175	6917	GO:00325….
query_1	TRUE	0.0133081	25	912	6	0.0065789	0.2400000	GO:0010669	GO:BP	epithelial structure maintenance	16175	4314	GO:0001894
query_1	TRUE	0.0133081	25	912	6	0.0065789	0.2400000	GO:0032814	GO:BP	regulation of natural killer cell activation	16175	7838	GO:00301….
query_1	TRUE	0.0133081	25	912	6	0.0065789	0.2400000	GO:1904994	GO:BP	regulation of leukocyte adhesion to vascular endothelial cell	16175	24279	GO:00617….
query_1	TRUE	0.0137417	62	912	10	0.0109649	0.1612903	GO:0062208	GO:BP	positive regulation of pattern recognition receptor signaling pathway	16175	15864	GO:00022….
query_1	TRUE	0.0137417	62	912	10	0.0109649	0.1612903	GO:0051057	GO:BP	positive regulation of small GTPase mediated signal transduction	16175	13467	GO:00072….
query_1	TRUE	0.0137485	83	912	12	0.0131579	0.1445783	GO:0046425	GO:BP	regulation of receptor signaling pathway via JAK-STAT	16175	12135	GO:00072….
query_1	TRUE	0.0137485	83	912	12	0.0131579	0.1445783	GO:0046718	GO:BP	symbiont entry into host cell	16175	12339	GO:00190….
query_1	TRUE	0.0142681	11	912	4	0.0043860	0.3636364	GO:0045061	GO:BP	thymic T cell selection	16175	11259	GO:00330….
query_1	TRUE	0.0142681	11	912	4	0.0043860	0.3636364	GO:0036005	GO:BP	response to macrophage colony-stimulating factor	16175	9388	GO:0034097
query_1	TRUE	0.0142681	11	912	4	0.0043860	0.3636364	GO:0034154	GO:BP	toll-like receptor 7 signaling pathway	16175	8462	GO:0140894
query_1	TRUE	0.0142681	11	912	4	0.0043860	0.3636364	GO:0045579	GO:BP	positive regulation of B cell differentiation	16175	11430	GO:00301….
query_1	TRUE	0.0142681	11	912	4	0.0043860	0.3636364	GO:0036006	GO:BP	cellular response to macrophage colony-stimulating factor stimulus	16175	9389	GO:00360….
query_1	TRUE	0.0142681	11	912	4	0.0043860	0.3636364	GO:0090102	GO:BP	cochlea development	16175	18020	GO:00488….
query_1	TRUE	0.0142681	11	912	4	0.0043860	0.3636364	GO:0048532	GO:BP	anatomical structure arrangement	16175	12813	GO:00096….
query_1	TRUE	0.0142681	11	912	4	0.0043860	0.3636364	GO:1901731	GO:BP	positive regulation of platelet aggregation	16175	21675	GO:00341….
query_1	TRUE	0.0145057	129	912	16	0.0175439	0.1240310	GO:1904018	GO:BP	positive regulation of vasculature development	16175	23459	GO:00019….
query_1	TRUE	0.0145717	153	912	18	0.0197368	0.1176471	GO:0008154	GO:BP	actin polymerization or depolymerization	16175	3127	GO:0007015
query_1	TRUE	0.0145749	43	912	8	0.0087719	0.1860465	GO:0050850	GO:BP	positive regulation of calcium-mediated signaling	16175	13298	GO:00197….
query_1	TRUE	0.0147136	34	912	7	0.0076754	0.2058824	GO:0045214	GO:BP	sarcomere organization	16175	11327	GO:00302….
query_1	TRUE	0.0147136	34	912	7	0.0076754	0.2058824	GO:1902041	GO:BP	regulation of extrinsic apoptotic signaling pathway via death domain receptors	16175	21964	GO:00086….
query_1	TRUE	0.0149208	404	912	37	0.0405702	0.0915842	GO:1903530	GO:BP	regulation of secretion by cell	16175	23080	GO:00329….
query_1	TRUE	0.0150158	84	912	12	0.0131579	0.1428571	GO:0033209	GO:BP	tumor necrosis factor-mediated signaling pathway	16175	8075	GO:00192….
query_1	TRUE	0.0150887	242	912	25	0.0274123	0.1033058	GO:0051056	GO:BP	regulation of small GTPase mediated signal transduction	16175	13466	GO:00072….
query_1	TRUE	0.0152425	63	912	10	0.0109649	0.1587302	GO:0008625	GO:BP	extrinsic apoptotic signaling pathway via death domain receptors	16175	3214	GO:0097191
query_1	TRUE	0.0152751	18	912	5	0.0054825	0.2777778	GO:0045624	GO:BP	positive regulation of T-helper cell differentiation	16175	11475	GO:00026….
query_1	TRUE	0.0152751	18	912	5	0.0054825	0.2777778	GO:0043032	GO:BP	positive regulation of macrophage activation	16175	10487	GO:00026….
query_1	TRUE	0.0152751	18	912	5	0.0054825	0.2777778	GO:2000353	GO:BP	positive regulation of endothelial cell apoptotic process	16175	25672	GO:00430….
query_1	TRUE	0.0156655	350	912	33	0.0361842	0.0942857	GO:0016032	GO:BP	viral process	16175	5071	GO:0008150
query_1	TRUE	0.0160447	26	912	6	0.0065789	0.2307692	GO:2000316	GO:BP	regulation of T-helper 17 type immune response	16175	25638	GO:00028….
query_1	TRUE	0.0160447	26	912	6	0.0065789	0.2307692	GO:0090330	GO:BP	regulation of platelet aggregation	16175	18210	GO:00105….
query_1	TRUE	0.0160447	26	912	6	0.0065789	0.2307692	GO:0071676	GO:BP	negative regulation of mononuclear cell migration	16175	16849	GO:00026….
query_1	TRUE	0.0161146	283	912	28	0.0307018	0.0989399	GO:0001501	GO:BP	skeletal system development	16175	318	GO:0048731
query_1	TRUE	0.0162098	534	912	46	0.0504386	0.0861423	GO:0055082	GO:BP	intracellular chemical homeostasis	16175	14235	GO:00197….
query_1	TRUE	0.0164766	463	912	41	0.0449561	0.0885529	GO:0097190	GO:BP	apoptotic signaling pathway	16175	18534	GO:00069….
query_1	TRUE	0.0169763	64	912	10	0.0109649	0.1562500	GO:0032418	GO:BP	lysosome localization	16175	7556	GO:1990849
query_1	TRUE	0.0169763	64	912	10	0.0109649	0.1562500	GO:1990849	GO:BP	vacuolar localization	16175	25315	GO:0051640
query_1	TRUE	0.0171960	35	912	7	0.0076754	0.2000000	GO:0032620	GO:BP	interleukin-17 production	16175	7667	GO:0001816
query_1	TRUE	0.0171960	35	912	7	0.0076754	0.2000000	GO:0097242	GO:BP	amyloid-beta clearance	16175	18557	GO:0032501
query_1	TRUE	0.0171960	35	912	7	0.0076754	0.2000000	GO:0032660	GO:BP	regulation of interleukin-17 production	16175	7706	GO:00018….
query_1	TRUE	0.0174168	6	912	3	0.0032895	0.5000000	GO:0072679	GO:BP	thymocyte migration	16175	17497	GO:0072678
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:2000448	GO:BP	positive regulation of macrophage migration inhibitory factor signaling pathway	16175	25763	GO:00019….
query_1	TRUE	0.0174168	6	912	3	0.0032895	0.5000000	GO:2000669	GO:BP	negative regulation of dendritic cell apoptotic process	16175	25944	GO:00970….
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:1904999	GO:BP	positive regulation of leukocyte adhesion to arterial endothelial cell	16175	24284	GO:00617….
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:2000446	GO:BP	regulation of macrophage migration inhibitory factor signaling pathway	16175	25761	GO:00019….
query_1	TRUE	0.0174168	6	912	3	0.0032895	0.5000000	GO:1903969	GO:BP	regulation of response to macrophage colony-stimulating factor	16175	23426	GO:00360….
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:2000473	GO:BP	positive regulation of hematopoietic stem cell migration	16175	25785	GO:00303….
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:1904270	GO:BP	pyroptosome complex assembly	16175	23661	GO:0065003
query_1	TRUE	0.0174168	6	912	3	0.0032895	0.5000000	GO:0097490	GO:BP	sympathetic neuron projection extension	16175	18674	GO:1990138
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:1903971	GO:BP	positive regulation of response to macrophage colony-stimulating factor	16175	23428	GO:00360….
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:2000361	GO:BP	regulation of prostaglandin-E synthase activity	16175	25680	GO:0010911
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:0140039	GO:BP	cell-cell adhesion in response to extracellular stimulus	16175	19643	GO:00517….
query_1	TRUE	0.0174168	6	912	3	0.0032895	0.5000000	GO:0032306	GO:BP	regulation of prostaglandin secretion	16175	7476	GO:00323….
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:1902216	GO:BP	positive regulation of interleukin-4-mediated signaling pathway	16175	22115	GO:00019….
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:1903974	GO:BP	positive regulation of cellular response to macrophage colony-stimulating factor stimulus	16175	23431	GO:00360….
query_1	TRUE	0.0174168	6	912	3	0.0032895	0.5000000	GO:1903972	GO:BP	regulation of cellular response to macrophage colony-stimulating factor stimulus	16175	23429	GO:00360….
query_1	TRUE	0.0174168	6	912	3	0.0032895	0.5000000	GO:1904141	GO:BP	positive regulation of microglial cell migration	16175	23563	GO:19039….
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:0140105	GO:BP	interleukin-10-mediated signaling pathway	16175	19666	GO:0019221
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:2000349	GO:BP	negative regulation of CD40 signaling pathway	16175	25668	GO:00099….
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:1904172	GO:BP	positive regulation of bleb assembly	16175	23585	GO:00320….
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:0140973	GO:BP	positive regulation of AIM2 inflammasome complex assembly	16175	19957	GO:00313….
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:1904155	GO:BP	DN2 thymocyte differentiation	16175	23576	GO:0033077
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:1904170	GO:BP	regulation of bleb assembly	16175	23583	GO:00320….
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:2000363	GO:BP	positive regulation of prostaglandin-E synthase activity	16175	25681	GO:00109….
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:0090291	GO:BP	negative regulation of osteoclast proliferation	16175	18175	GO:00021….
query_1	TRUE	0.0174168	6	912	3	0.0032895	0.5000000	GO:0051715	GO:BP	cytolysis in another organism	16175	13908	GO:00198….
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:2000471	GO:BP	regulation of hematopoietic stem cell migration	16175	25783	GO:00303….
query_1	TRUE	0.0174168	6	912	3	0.0032895	0.5000000	GO:0070106	GO:BP	interleukin-27-mediated signaling pathway	16175	15918	GO:0019221
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:0002270	GO:BP	plasmacytoid dendritic cell activation	16175	802	GO:0045321
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:0045658	GO:BP	regulation of neutrophil differentiation	16175	11509	GO:00302….
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:0034125	GO:BP	negative regulation of MyD88-dependent toll-like receptor signaling pathway	16175	8433	GO:00027….
query_1	TRUE	0.0174168	6	912	3	0.0032895	0.5000000	GO:0060729	GO:BP	intestinal epithelial structure maintenance	16175	14898	GO:0030277
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:0045914	GO:BP	negative regulation of catecholamine metabolic process	16175	11708	GO:00065….
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:0045963	GO:BP	negative regulation of dopamine metabolic process	16175	11755	GO:00420….
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:0060346	GO:BP	bone trabecula formation	16175	14557	GO:00487….
query_1	TRUE	0.0174168	6	912	3	0.0032895	0.5000000	GO:0048934	GO:BP	peripheral nervous system neuron differentiation	16175	13174	GO:00074….
query_1	TRUE	0.0174168	6	912	3	0.0032895	0.5000000	GO:0060075	GO:BP	regulation of resting membrane potential	16175	14336	GO:0042391
query_1	TRUE	0.0174168	6	912	3	0.0032895	0.5000000	GO:0048935	GO:BP	peripheral nervous system neuron development	16175	13175	GO:00486….
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:0002588	GO:BP	positive regulation of antigen processing and presentation of peptide antigen via MHC class II	16175	1109	GO:00024….
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:0002587	GO:BP	negative regulation of antigen processing and presentation of peptide antigen via MHC class II	16175	1108	GO:00024….
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:0033082	GO:BP	regulation of extrathymic T cell differentiation	16175	8030	GO:00330….
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:0002585	GO:BP	positive regulation of antigen processing and presentation of peptide antigen	16175	1106	GO:00025….
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:0002582	GO:BP	positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	16175	1103	GO:00025….
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:0002296	GO:BP	T-helper 1 cell lineage commitment	16175	828	GO:00022….
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:2000458	GO:BP	regulation of astrocyte chemotaxis	16175	25773	GO:00357….
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:0033078	GO:BP	extrathymic T cell differentiation	16175	8026	GO:0030217
query_1	TRUE	0.0174168	6	912	3	0.0032895	0.5000000	GO:0030854	GO:BP	positive regulation of granulocyte differentiation	16175	6937	GO:00027….
query_1	TRUE	0.0174168	6	912	3	0.0032895	0.5000000	GO:0021636	GO:BP	trigeminal nerve morphogenesis	16175	6219	GO:00215….
query_1	TRUE	0.0174168	6	912	3	0.0032895	0.5000000	GO:0032741	GO:BP	positive regulation of interleukin-18 production	16175	7785	GO:00018….
query_1	TRUE	0.0174168	6	912	3	0.0032895	0.5000000	GO:0042270	GO:BP	protection from natural killer cell mediated cytotoxicity	16175	10068	GO:0045953
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:0038124	GO:BP	toll-like receptor TLR6:TLR2 signaling pathway	16175	9715	GO:0002224
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:0042496	GO:BP	detection of diacyl bacterial lipopeptide	16175	10224	GO:00703….
query_1	TRUE	0.0174168	6	912	3	0.0032895	0.5000000	GO:0021785	GO:BP	branchiomotor neuron axon guidance	16175	6363	GO:0008045
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:0072377	GO:BP	blood coagulation, common pathway	16175	17374	GO:00723….
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:0035700	GO:BP	astrocyte chemotaxis	16175	9174	GO:00436….
query_1	TRUE	0.0174168	6	912	3	0.0032895	0.5000000	GO:0021637	GO:BP	trigeminal nerve structural organization	16175	6220	GO:00216….
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:0035691	GO:BP	macrophage migration inhibitory factor signaling pathway	16175	9167	GO:0019221
query_1	TRUE	0.0174168	2	912	2	0.0021930	1.0000000	GO:0042495	GO:BP	detection of triacyl bacterial lipopeptide	16175	10223	GO:00703….
query_1	TRUE	0.0174168	6	912	3	0.0032895	0.5000000	GO:0001865	GO:BP	NK T cell differentiation	16175	502	GO:0046632
query_1	TRUE	0.0181107	510	912	44	0.0482456	0.0862745	GO:0007169	GO:BP	cell surface receptor protein tyrosine kinase signaling pathway	16175	2733	GO:0007167
query_1	TRUE	0.0181712	45	912	8	0.0087719	0.1777778	GO:0055013	GO:BP	cardiac muscle cell development	16175	14202	GO:00550….
query_1	TRUE	0.0183177	19	912	5	0.0054825	0.2631579	GO:1900227	GO:BP	positive regulation of NLRP3 inflammasome complex assembly	16175	20499	GO:00313….
query_1	TRUE	0.0183177	19	912	5	0.0054825	0.2631579	GO:0002052	GO:BP	positive regulation of neuroblast proliferation	16175	651	GO:00074….
query_1	TRUE	0.0183177	19	912	5	0.0054825	0.2631579	GO:0043302	GO:BP	positive regulation of leukocyte degranulation	16175	10610	GO:00026….
query_1	TRUE	0.0183177	19	912	5	0.0054825	0.2631579	GO:2000319	GO:BP	regulation of T-helper 17 cell differentiation	16175	25641	GO:00456….
query_1	TRUE	0.0183177	19	912	5	0.0054825	0.2631579	GO:0030449	GO:BP	regulation of complement activation	16175	6807	GO:00026….
query_1	TRUE	0.0183177	19	912	5	0.0054825	0.2631579	GO:0016553	GO:BP	base conversion or substitution editing	16175	5244	GO:0009451
query_1	TRUE	0.0183177	19	912	5	0.0054825	0.2631579	GO:0002335	GO:BP	mature B cell differentiation	16175	867	GO:0030183
query_1	TRUE	0.0183177	27	912	6	0.0065789	0.2222222	GO:0031641	GO:BP	regulation of myelination	16175	7251	GO:00425….
query_1	TRUE	0.0183177	19	912	5	0.0054825	0.2631579	GO:0090026	GO:BP	positive regulation of monocyte chemotaxis	16175	17960	GO:00025….
query_1	TRUE	0.0183177	19	912	5	0.0054825	0.2631579	GO:0046597	GO:BP	negative regulation of viral entry into host cell	16175	12247	GO:00465….
query_1	TRUE	0.0183556	55	912	9	0.0098684	0.1636364	GO:0006801	GO:BP	superoxide metabolic process	16175	2486	GO:0072593
query_1	TRUE	0.0183556	55	912	9	0.0098684	0.1636364	GO:0051289	GO:BP	protein homotetramerization	16175	13621	GO:00512….
query_1	TRUE	0.0186077	12	912	4	0.0043860	0.3333333	GO:0035666	GO:BP	TRIF-dependent toll-like receptor signaling pathway	16175	9146	GO:0002756
query_1	TRUE	0.0186077	12	912	4	0.0043860	0.3333333	GO:0048486	GO:BP	parasympathetic nervous system development	16175	12780	GO:00484….
query_1	TRUE	0.0186077	12	912	4	0.0043860	0.3333333	GO:0042454	GO:BP	ribonucleoside catabolic process	16175	10193	GO:00091….
query_1	TRUE	0.0186077	12	912	4	0.0043860	0.3333333	GO:0002430	GO:BP	complement receptor mediated signaling pathway	16175	953	GO:0002429
query_1	TRUE	0.0186077	12	912	4	0.0043860	0.3333333	GO:0002357	GO:BP	defense response to tumor cell	16175	889	GO:00023….
query_1	TRUE	0.0189070	36	912	7	0.0076754	0.1944444	GO:0003009	GO:BP	skeletal muscle contraction	16175	1460	GO:00069….
query_1	TRUE	0.0208672	123	912	15	0.0164474	0.1219512	GO:0071902	GO:BP	positive regulation of protein serine/threonine kinase activity	16175	16973	GO:00458….
query_1	TRUE	0.0212756	185	912	20	0.0219298	0.1081081	GO:0022604	GO:BP	regulation of cell morphogenesis	16175	6612	GO:00009….
query_1	TRUE	0.0219357	28	912	6	0.0065789	0.2142857	GO:0030224	GO:BP	monocyte differentiation	16175	6732	GO:00025….
query_1	TRUE	0.0219357	28	912	6	0.0065789	0.2142857	GO:0030866	GO:BP	cortical actin cytoskeleton organization	16175	6947	GO:00300….
query_1	TRUE	0.0220507	67	912	10	0.0109649	0.1492537	GO:0001960	GO:BP	negative regulation of cytokine-mediated signaling pathway	16175	569	GO:00019….
query_1	TRUE	0.0223435	305	912	29	0.0317982	0.0950820	GO:0043086	GO:BP	negative regulation of catalytic activity	16175	10519	GO:00440….
query_1	TRUE	0.0227875	431	912	38	0.0416667	0.0881671	GO:1901699	GO:BP	cellular response to nitrogen compound	16175	21652	GO:00708….
query_1	TRUE	0.0229173	20	912	5	0.0054825	0.2500000	GO:0010463	GO:BP	mesenchymal cell proliferation	16175	4157	GO:0008283
query_1	TRUE	0.0229173	20	912	5	0.0054825	0.2500000	GO:1905523	GO:BP	positive regulation of macrophage migration	16175	24699	GO:00716….
query_1	TRUE	0.0229173	20	912	5	0.0054825	0.2500000	GO:0060142	GO:BP	regulation of syncytium formation by plasma membrane fusion	16175	14386	GO:00007….
query_1	TRUE	0.0229173	20	912	5	0.0054825	0.2500000	GO:0006910	GO:BP	phagocytosis, recognition	16175	2560	GO:00069….
query_1	TRUE	0.0230835	57	912	9	0.0098684	0.1578947	GO:0030193	GO:BP	regulation of blood coagulation	16175	6704	GO:00075….
query_1	TRUE	0.0230835	57	912	9	0.0098684	0.1578947	GO:0006809	GO:BP	nitric oxide biosynthetic process	16175	2489	GO:00090….
query_1	TRUE	0.0230835	57	912	9	0.0098684	0.1578947	GO:0007492	GO:BP	endoderm development	16175	2978	GO:0009888
query_1	TRUE	0.0233149	47	912	8	0.0087719	0.1702128	GO:0001656	GO:BP	metanephros development	16175	370	GO:0001822
query_1	TRUE	0.0233935	279	912	27	0.0296053	0.0967742	GO:0031589	GO:BP	cell-substrate adhesion	16175	7233	GO:0007155
query_1	TRUE	0.0238100	113	912	14	0.0153509	0.1238938	GO:0008064	GO:BP	regulation of actin polymerization or depolymerization	16175	3113	GO:00081….
query_1	TRUE	0.0239026	266	912	26	0.0285088	0.0977444	GO:0051960	GO:BP	regulation of nervous system development	16175	14029	GO:00073….
query_1	TRUE	0.0239331	125	912	15	0.0164474	0.1200000	GO:0045766	GO:BP	positive regulation of angiogenesis	16175	11602	GO:00015….
query_1	TRUE	0.0240188	90	912	12	0.0131579	0.1333333	GO:0097305	GO:BP	response to alcohol	16175	18586	GO:1901700
query_1	TRUE	0.0240188	90	912	12	0.0131579	0.1333333	GO:0044409	GO:BP	symbiont entry into host	16175	10994	GO:0051701
query_1	TRUE	0.0240188	90	912	12	0.0131579	0.1333333	GO:1904892	GO:BP	regulation of receptor signaling pathway via STAT	16175	24199	GO:00099….
query_1	TRUE	0.0250252	13	912	4	0.0043860	0.3076923	GO:0150078	GO:BP	positive regulation of neuroinflammatory response	16175	20130	GO:00507….
query_1	TRUE	0.0250252	13	912	4	0.0043860	0.3076923	GO:2000402	GO:BP	negative regulation of lymphocyte migration	16175	25717	GO:00716….
query_1	TRUE	0.0250252	13	912	4	0.0043860	0.3076923	GO:0051767	GO:BP	nitric-oxide synthase biosynthetic process	16175	13924	GO:0009059
query_1	TRUE	0.0250252	13	912	4	0.0043860	0.3076923	GO:0002830	GO:BP	positive regulation of type 2 immune response	16175	1340	GO:00028….
query_1	TRUE	0.0250252	13	912	4	0.0043860	0.3076923	GO:0002922	GO:BP	positive regulation of humoral immune response	16175	1432	GO:00029….
query_1	TRUE	0.0250252	13	912	4	0.0043860	0.3076923	GO:0051769	GO:BP	regulation of nitric-oxide synthase biosynthetic process	16175	13925	GO:00105….
query_1	TRUE	0.0250252	13	912	4	0.0043860	0.3076923	GO:0031665	GO:BP	negative regulation of lipopolysaccharide-mediated signaling pathway	16175	7269	GO:00028….
query_1	TRUE	0.0251868	38	912	7	0.0076754	0.1842105	GO:0032728	GO:BP	positive regulation of interferon-beta production	16175	7773	GO:00324….
query_1	TRUE	0.0251868	38	912	7	0.0076754	0.1842105	GO:0021675	GO:BP	nerve development	16175	6258	GO:00073….
query_1	TRUE	0.0251868	38	912	7	0.0076754	0.1842105	GO:0061515	GO:BP	myeloid cell development	16175	15516	GO:00300….
query_1	TRUE	0.0251868	38	912	7	0.0076754	0.1842105	GO:1905330	GO:BP	regulation of morphogenesis of an epithelium	16175	24546	GO:00020….
query_1	TRUE	0.0255429	58	912	9	0.0098684	0.1551724	GO:1900046	GO:BP	regulation of hemostasis	16175	20348	GO:00075….
query_1	TRUE	0.0256393	29	912	6	0.0065789	0.2068966	GO:0045124	GO:BP	regulation of bone resorption	16175	11290	GO:00454….
query_1	TRUE	0.0256393	29	912	6	0.0065789	0.2068966	GO:0039694	GO:BP	viral RNA genome replication	16175	9871	GO:00190….
query_1	TRUE	0.0260769	551	912	46	0.0504386	0.0834846	GO:1902532	GO:BP	negative regulation of intracellular signal transduction	16175	22341	GO:00099….
query_1	TRUE	0.0261023	48	912	8	0.0087719	0.1666667	GO:0061097	GO:BP	regulation of protein tyrosine kinase activity	16175	15207	GO:00458….
query_1	TRUE	0.0262584	407	912	36	0.0394737	0.0884521	GO:0007015	GO:BP	actin filament organization	16175	2624	GO:00300….
query_1	TRUE	0.0265544	80	912	11	0.0120614	0.1375000	GO:0050829	GO:BP	defense response to Gram-negative bacterium	16175	13287	GO:0042742
query_1	TRUE	0.0268590	552	912	46	0.0504386	0.0833333	GO:0035239	GO:BP	tube morphogenesis	16175	8921	GO:00096….
query_1	TRUE	0.0270514	7	912	3	0.0032895	0.4285714	GO:0071355	GO:BP	cellular response to interleukin-9	16175	16607	GO:00711….
query_1	TRUE	0.0270514	7	912	3	0.0032895	0.4285714	GO:0035701	GO:BP	hematopoietic stem cell migration	16175	9175	GO:0016477
query_1	TRUE	0.0270514	7	912	3	0.0032895	0.4285714	GO:0072203	GO:BP	cell proliferation involved in metanephros development	16175	17234	GO:00016….
query_1	TRUE	0.0270514	7	912	3	0.0032895	0.4285714	GO:0038113	GO:BP	interleukin-9-mediated signaling pathway	16175	9707	GO:00192….
query_1	TRUE	0.0270514	7	912	3	0.0032895	0.4285714	GO:0045625	GO:BP	regulation of T-helper 1 cell differentiation	16175	11476	GO:00028….
query_1	TRUE	0.0270514	7	912	3	0.0032895	0.4285714	GO:0010911	GO:BP	regulation of isomerase activity	16175	4496	GO:0050790
query_1	TRUE	0.0270514	7	912	3	0.0032895	0.4285714	GO:0010912	GO:BP	positive regulation of isomerase activity	16175	4497	GO:00109….
query_1	TRUE	0.0270514	7	912	3	0.0032895	0.4285714	GO:1903753	GO:BP	negative regulation of p38MAPK cascade	16175	23254	GO:00380….
query_1	TRUE	0.0270514	671	912	54	0.0592105	0.0804769	GO:0034220	GO:BP	monoatomic ion transmembrane transport	16175	8508	GO:00068….
query_1	TRUE	0.0270514	7	912	3	0.0032895	0.4285714	GO:2000562	GO:BP	negative regulation of CD4-positive, alpha-beta T cell proliferation	16175	25863	GO:00357….
query_1	TRUE	0.0270514	7	912	3	0.0032895	0.4285714	GO:0051797	GO:BP	regulation of hair follicle development	16175	13944	GO:00019….
query_1	TRUE	0.0270514	7	912	3	0.0032895	0.4285714	GO:0002829	GO:BP	negative regulation of type 2 immune response	16175	1339	GO:00028….
query_1	TRUE	0.0270514	7	912	3	0.0032895	0.4285714	GO:0002544	GO:BP	chronic inflammatory response	16175	1065	GO:0006954
query_1	TRUE	0.0270514	7	912	3	0.0032895	0.4285714	GO:0060558	GO:BP	regulation of calcidiol 1-monooxygenase activity	16175	14742	GO:0032768
query_1	TRUE	0.0270514	7	912	3	0.0032895	0.4285714	GO:0033005	GO:BP	positive regulation of mast cell activation	16175	7974	GO:00026….
query_1	TRUE	0.0274765	21	912	5	0.0054825	0.2380952	GO:0002726	GO:BP	positive regulation of T cell cytokine production	16175	1244	GO:00023….
query_1	TRUE	0.0274765	21	912	5	0.0054825	0.2380952	GO:0046639	GO:BP	negative regulation of alpha-beta T cell differentiation	16175	12276	GO:00455….
query_1	TRUE	0.0274765	152	912	17	0.0186404	0.1118421	GO:0001894	GO:BP	tissue homeostasis	16175	519	GO:00488….
query_1	TRUE	0.0274765	21	912	5	0.0054825	0.2380952	GO:0060055	GO:BP	angiogenesis involved in wound healing	16175	14317	GO:00015….
query_1	TRUE	0.0274765	152	912	17	0.0186404	0.1118421	GO:0060249	GO:BP	anatomical structure homeostasis	16175	14466	GO:0048871
query_1	TRUE	0.0274765	21	912	5	0.0054825	0.2380952	GO:0031646	GO:BP	positive regulation of nervous system process	16175	7256	GO:00316….
query_1	TRUE	0.0279501	59	912	9	0.0098684	0.1525424	GO:0050818	GO:BP	regulation of coagulation	16175	13280	GO:00508….
query_1	TRUE	0.0279501	59	912	9	0.0098684	0.1525424	GO:0022617	GO:BP	extracellular matrix disassembly	16175	6624	GO:00224….
query_1	TRUE	0.0281510	165	912	18	0.0197368	0.1090909	GO:0001659	GO:BP	temperature homeostasis	16175	373	GO:0048871
query_1	TRUE	0.0289952	49	912	8	0.0087719	0.1632653	GO:0039532	GO:BP	negative regulation of cytoplasmic pattern recognition receptor signaling pathway	16175	9805	GO:00026….
query_1	TRUE	0.0292149	439	912	38	0.0416667	0.0865604	GO:0003013	GO:BP	circulatory system process	16175	1464	GO:0003008
query_1	TRUE	0.0293658	354	912	32	0.0350877	0.0903955	GO:0034762	GO:BP	regulation of transmembrane transport	16175	8731	GO:00507….
query_1	TRUE	0.0296844	30	912	6	0.0065789	0.2000000	GO:0035456	GO:BP	response to interferon-beta	16175	9044	GO:0034097
query_1	TRUE	0.0296844	30	912	6	0.0065789	0.2000000	GO:0010951	GO:BP	negative regulation of endopeptidase activity	16175	4529	GO:00104….
query_1	TRUE	0.0303489	192	912	20	0.0219298	0.1041667	GO:0007160	GO:BP	cell-matrix adhesion	16175	2724	GO:0031589
query_1	TRUE	0.0320793	14	912	4	0.0043860	0.2857143	GO:0002486	GO:BP	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent	16175	1009	GO:0002484
query_1	TRUE	0.0320793	14	912	4	0.0043860	0.2857143	GO:0035743	GO:BP	CD4-positive, alpha-beta T cell cytokine production	16175	9208	GO:0002369
query_1	TRUE	0.0320793	14	912	4	0.0043860	0.2857143	GO:0075294	GO:BP	positive regulation by symbiont of entry into host	16175	17706	GO:00444….
query_1	TRUE	0.0320793	14	912	4	0.0043860	0.2857143	GO:0002888	GO:BP	positive regulation of myeloid leukocyte mediated immunity	16175	1398	GO:00024….
query_1	TRUE	0.0320793	14	912	4	0.0043860	0.2857143	GO:0043931	GO:BP	ossification involved in bone maturation	16175	10861	GO:00015….
query_1	TRUE	0.0320793	14	912	4	0.0043860	0.2857143	GO:0046598	GO:BP	positive regulation of viral entry into host cell	16175	12248	GO:00465….
query_1	TRUE	0.0320793	14	912	4	0.0043860	0.2857143	GO:0002484	GO:BP	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway	16175	1007	GO:0019885
query_1	TRUE	0.0320793	14	912	4	0.0043860	0.2857143	GO:0034116	GO:BP	positive regulation of heterotypic cell-cell adhesion	16175	8424	GO:00224….
query_1	TRUE	0.0320793	14	912	4	0.0043860	0.2857143	GO:0032930	GO:BP	positive regulation of superoxide anion generation	16175	7921	GO:00329….
query_1	TRUE	0.0323858	40	912	7	0.0076754	0.1750000	GO:0010950	GO:BP	positive regulation of endopeptidase activity	16175	4528	GO:00109….
query_1	TRUE	0.0323858	40	912	7	0.0076754	0.1750000	GO:0043506	GO:BP	regulation of JUN kinase activity	16175	10743	GO:0043405
query_1	TRUE	0.0323934	50	912	8	0.0087719	0.1600000	GO:0055006	GO:BP	cardiac cell development	16175	14195	GO:00350….
query_1	TRUE	0.0330573	118	912	14	0.0153509	0.1186441	GO:0046328	GO:BP	regulation of JNK cascade	16175	12061	GO:00072….
query_1	TRUE	0.0332653	22	912	5	0.0054825	0.2272727	GO:0002433	GO:BP	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis	16175	956	GO:00022….
query_1	TRUE	0.0332653	22	912	5	0.0054825	0.2272727	GO:0038096	GO:BP	Fc-gamma receptor signaling pathway involved in phagocytosis	16175	9696	GO:00024….
query_1	TRUE	0.0333133	207	912	21	0.0230263	0.1014493	GO:0014706	GO:BP	striated muscle tissue development	16175	4643	GO:0060537
query_1	TRUE	0.0354641	119	912	14	0.0153509	0.1176471	GO:0010001	GO:BP	glial cell differentiation	16175	3822	GO:00301….
query_1	TRUE	0.0354680	182	912	19	0.0208333	0.1043956	GO:0007517	GO:BP	muscle organ development	16175	2999	GO:00485….
query_1	TRUE	0.0356085	262	912	25	0.0274123	0.0954198	GO:0034765	GO:BP	regulation of monoatomic ion transmembrane transport	16175	8734	GO:00342….
query_1	TRUE	0.0356761	235	912	23	0.0252193	0.0978723	GO:0071900	GO:BP	regulation of protein serine/threonine kinase activity	16175	16971	GO:0045859
query_1	TRUE	0.0356944	577	912	47	0.0515351	0.0814558	GO:0098655	GO:BP	monoatomic cation transmembrane transport	16175	18811	GO:00068….
query_1	TRUE	0.0368026	41	912	7	0.0076754	0.1707317	GO:0050879	GO:BP	multicellular organismal movement	16175	13324	GO:0032501
query_1	TRUE	0.0368026	41	912	7	0.0076754	0.1707317	GO:0050881	GO:BP	musculoskeletal movement	16175	13325	GO:00508….
query_1	TRUE	0.0368026	41	912	7	0.0076754	0.1707317	GO:0000768	GO:BP	syncytium formation by plasma membrane fusion	16175	234	GO:00069….
query_1	TRUE	0.0378314	62	912	9	0.0098684	0.1451613	GO:0046209	GO:BP	nitric oxide metabolic process	16175	11975	GO:2001057
query_1	TRUE	0.0397197	8	912	3	0.0032895	0.3750000	GO:0002278	GO:BP	eosinophil activation involved in immune response	16175	810	GO:00022….
query_1	TRUE	0.0397197	23	912	5	0.0054825	0.2173913	GO:0038095	GO:BP	Fc-epsilon receptor signaling pathway	16175	9695	GO:0038093
query_1	TRUE	0.0397197	8	912	3	0.0032895	0.3750000	GO:0002447	GO:BP	eosinophil mediated immunity	16175	970	GO:0002444
query_1	TRUE	0.0397197	23	912	5	0.0054825	0.2173913	GO:0001516	GO:BP	prostaglandin biosynthetic process	16175	326	GO:00066….
query_1	TRUE	0.0397197	23	912	5	0.0054825	0.2173913	GO:0072210	GO:BP	metanephric nephron development	16175	17241	GO:00016….
query_1	TRUE	0.0397197	23	912	5	0.0054825	0.2173913	GO:0046457	GO:BP	prostanoid biosynthetic process	16175	12165	GO:00066….
query_1	TRUE	0.0397197	8	912	3	0.0032895	0.3750000	GO:0043308	GO:BP	eosinophil degranulation	16175	10616	GO:00022….
query_1	TRUE	0.0397197	8	912	3	0.0032895	0.3750000	GO:0042590	GO:BP	antigen processing and presentation of exogenous peptide antigen via MHC class I	16175	10251	GO:00024….
query_1	TRUE	0.0397197	8	912	3	0.0032895	0.3750000	GO:0035630	GO:BP	bone mineralization involved in bone maturation	16175	9128	GO:00302….
query_1	TRUE	0.0397197	8	912	3	0.0032895	0.3750000	GO:0051712	GO:BP	positive regulation of killing of cells of another organism	16175	13907	GO:00313….
query_1	TRUE	0.0397197	8	912	3	0.0032895	0.3750000	GO:0019835	GO:BP	cytolysis	16175	6047	GO:0009987
query_1	TRUE	0.0397197	8	912	3	0.0032895	0.3750000	GO:2000343	GO:BP	positive regulation of chemokine (C-X-C motif) ligand 2 production	16175	25662	GO:00327….
query_1	TRUE	0.0397197	8	912	3	0.0032895	0.3750000	GO:0071801	GO:BP	regulation of podosome assembly	16175	16915	GO:00432….
query_1	TRUE	0.0397197	8	912	3	0.0032895	0.3750000	GO:0071104	GO:BP	response to interleukin-9	16175	16454	GO:0034097
query_1	TRUE	0.0397197	8	912	3	0.0032895	0.3750000	GO:0006957	GO:BP	complement activation, alternative pathway	16175	2588	GO:00069….
query_1	TRUE	0.0397197	8	912	3	0.0032895	0.3750000	GO:0051709	GO:BP	regulation of killing of cells of another organism	16175	13905	GO:00313….
query_1	TRUE	0.0397468	32	912	6	0.0065789	0.1875000	GO:0070266	GO:BP	necroptotic process	16175	16027	GO:0097300
query_1	TRUE	0.0398661	626	912	50	0.0548246	0.0798722	GO:0035295	GO:BP	tube development	16175	8953	GO:00072….
query_1	TRUE	0.0405465	15	912	4	0.0043860	0.2666667	GO:0035821	GO:BP	modulation of process of another organism	16175	9269	GO:0044419
query_1	TRUE	0.0405465	15	912	4	0.0043860	0.2666667	GO:0010464	GO:BP	regulation of mesenchymal cell proliferation	16175	4158	GO:00104….
query_1	TRUE	0.0405465	15	912	4	0.0043860	0.2666667	GO:0001845	GO:BP	phagolysosome assembly	16175	501	GO:00069….
query_1	TRUE	0.0405465	15	912	4	0.0043860	0.2666667	GO:0032928	GO:BP	regulation of superoxide anion generation	16175	7919	GO:00425….
query_1	TRUE	0.0406789	198	912	20	0.0219298	0.1010101	GO:0016485	GO:BP	protein processing	16175	5233	GO:00065….
query_1	TRUE	0.0411597	63	912	9	0.0098684	0.1428571	GO:2001057	GO:BP	reactive nitrogen species metabolic process	16175	26299	GO:0008152
query_1	TRUE	0.0411597	42	912	7	0.0076754	0.1666667	GO:0030838	GO:BP	positive regulation of actin filament polymerization	16175	6923	GO:00300….
query_1	TRUE	0.0411597	42	912	7	0.0076754	0.1666667	GO:0140253	GO:BP	cell-cell fusion	16175	19722	GO:0009987
query_1	TRUE	0.0412712	225	912	22	0.0241228	0.0977778	GO:0044403	GO:BP	biological process involved in symbiotic interaction	16175	10991	GO:0044419
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0002450	GO:BP	B cell antigen processing and presentation	16175	973	GO:00197….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0002436	GO:BP	immune complex clearance by monocytes and macrophages	16175	959	GO:0002434
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0060086	GO:BP	circadian temperature homeostasis	16175	14345	GO:00016….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0002465	GO:BP	peripheral tolerance induction	16175	988	GO:0002461
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0060474	GO:BP	positive regulation of flagellated sperm motility involved in capacitation	16175	14670	GO:00224….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0060559	GO:BP	positive regulation of calcidiol 1-monooxygenase activity	16175	14743	GO:00327….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:2000412	GO:BP	positive regulation of thymocyte migration	16175	25727	GO:00726….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0071226	GO:BP	cellular response to molecule of fungal origin	16175	16488	GO:00022….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0071608	GO:BP	macrophage inflammatory protein-1 alpha production	16175	16794	GO:0032602
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0051136	GO:BP	regulation of NK T cell differentiation	16175	13520	GO:00018….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0016068	GO:BP	type I hypersensitivity	16175	5096	GO:00025….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0033239	GO:BP	negative regulation of amine metabolic process	16175	8089	GO:00093….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0002581	GO:BP	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	16175	1102	GO:00025….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0031034	GO:BP	myosin filament assembly	16175	7006	GO:00310….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0038098	GO:BP	sequestering of BMP from receptor via BMP binding	16175	9698	GO:00305….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0042756	GO:BP	drinking behavior	16175	10349	GO:0007631
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0043315	GO:BP	positive regulation of neutrophil degranulation	16175	10623	GO:00028….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0043316	GO:BP	cytotoxic T cell degranulation	16175	10624	GO:00019….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0043317	GO:BP	regulation of cytotoxic T cell degranulation	16175	10625	GO:00019….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0043318	GO:BP	negative regulation of cytotoxic T cell degranulation	16175	10626	GO:00019….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0007079	GO:BP	mitotic chromosome movement towards spindle pole	16175	2668	GO:00000….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0006154	GO:BP	adenosine catabolic process	16175	1995	GO:00460….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0045728	GO:BP	respiratory burst after phagocytosis	16175	11570	GO:0002679
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0046103	GO:BP	inosine biosynthetic process	16175	11879	GO:00461….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0002826	GO:BP	negative regulation of T-helper 1 type immune response	16175	1336	GO:00028….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0046968	GO:BP	peptide antigen transport	16175	12453	GO:00158….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0048769	GO:BP	sarcomerogenesis	16175	13019	GO:00302….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0071626	GO:BP	mastication	16175	16806	GO:0022600
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0016046	GO:BP	detection of fungus	16175	5079	GO:00096….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0071640	GO:BP	regulation of macrophage inflammatory protein 1 alpha production	16175	16817	GO:00326….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0002238	GO:BP	response to molecule of fungal origin	16175	771	GO:00096….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0071688	GO:BP	striated muscle myosin thick filament assembly	16175	16856	GO:00109….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:2001199	GO:BP	negative regulation of dendritic cell differentiation	16175	26399	GO:00970….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:2001190	GO:BP	positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	16175	26390	GO:00022….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:1900623	GO:BP	regulation of monocyte aggregation	16175	20800	GO:00704….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:1900625	GO:BP	positive regulation of monocyte aggregation	16175	20802	GO:00704….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0071659	GO:BP	negative regulation of IP-10 production	16175	16836	GO:00326….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:2000697	GO:BP	negative regulation of epithelial cell differentiation involved in kidney development	16175	25965	GO:00308….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0160006	GO:BP	Fc receptor-mediated immune complex endocytosis	16175	20192	GO:00068….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:2000670	GO:BP	positive regulation of dendritic cell apoptotic process	16175	25945	GO:00970….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:1902564	GO:BP	negative regulation of neutrophil activation	16175	22355	GO:00026….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:1904093	GO:BP	negative regulation of autophagic cell death	16175	23522	GO:00430….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0030241	GO:BP	skeletal muscle myosin thick filament assembly	16175	6738	GO:00148….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:1904466	GO:BP	positive regulation of matrix metallopeptidase secretion	16175	23844	GO:00507….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:1905747	GO:BP	negative regulation of saliva secretion	16175	24868	GO:00465….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:1905748	GO:BP	hard palate morphogenesis	16175	24869	GO:0009653
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:1902214	GO:BP	regulation of interleukin-4-mediated signaling pathway	16175	22113	GO:00019….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0150102	GO:BP	negative regulation of monocyte activation	16175	20141	GO:00026….
query_1	TRUE	0.0426184	173	912	18	0.0197368	0.1040462	GO:0031032	GO:BP	actomyosin structure organization	16175	7004	GO:0030036
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0071727	GO:BP	cellular response to triacyl bacterial lipopeptide	16175	16887	GO:00712….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0110089	GO:BP	regulation of hippocampal neuron apoptotic process	16175	19404	GO:00435….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0110088	GO:BP	hippocampal neuron apoptotic process	16175	19403	GO:0051402
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0090076	GO:BP	relaxation of skeletal muscle	16175	18000	GO:0090075
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0071691	GO:BP	cardiac muscle thin filament assembly	16175	16859	GO:00070….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0071725	GO:BP	response to triacyl bacterial lipopeptide	16175	16885	GO:0070339
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0098583	GO:BP	learned vocalization behavior	16175	18800	GO:00716….
query_1	TRUE	0.0426184	3	912	2	0.0021930	0.6666667	GO:0090264	GO:BP	regulation of immune complex clearance by monocytes and macrophages	16175	18153	GO:00024….
query_1	TRUE	0.0426388	75	912	10	0.0109649	0.1333333	GO:0001938	GO:BP	positive regulation of endothelial cell proliferation	16175	552	GO:00019….
query_1	TRUE	0.0430916	254	912	24	0.0263158	0.0944882	GO:0001503	GO:BP	ossification	16175	320	GO:0032501
query_1	TRUE	0.0445892	43	912	7	0.0076754	0.1627907	GO:0045778	GO:BP	positive regulation of ossification	16175	11612	GO:00015….
query_1	TRUE	0.0445892	43	912	7	0.0076754	0.1627907	GO:0006949	GO:BP	syncytium formation	16175	2581	GO:00099….
query_1	TRUE	0.0445892	43	912	7	0.0076754	0.1627907	GO:0043407	GO:BP	negative regulation of MAP kinase activity	16175	10675	GO:00434….
query_1	TRUE	0.0449800	255	912	24	0.0263158	0.0941176	GO:0007610	GO:BP	behavior	16175	3067	GO:0032501
query_1	TRUE	0.0450615	24	912	5	0.0054825	0.2083333	GO:1903902	GO:BP	positive regulation of viral life cycle	16175	23369	GO:00190….
query_1	TRUE	0.0450615	24	912	5	0.0054825	0.2083333	GO:0060333	GO:BP	type II interferon-mediated signaling pathway	16175	14545	GO:00713….
query_1	TRUE	0.0450615	24	912	5	0.0054825	0.2083333	GO:0042730	GO:BP	fibrinolysis	16175	10330	GO:0030195
query_1	TRUE	0.0450615	24	912	5	0.0054825	0.2083333	GO:0061760	GO:BP	antifungal innate immune response	16175	15652	GO:00450….
query_1	TRUE	0.0463047	76	912	10	0.0109649	0.1315789	GO:0014902	GO:BP	myotube differentiation	16175	4777	GO:0051146
query_1	TRUE	0.0463047	76	912	10	0.0109649	0.1315789	GO:0051262	GO:BP	protein tetramerization	16175	13609	GO:0051259
query_1	TRUE	0.0475751	65	912	9	0.0098684	0.1384615	GO:1902893	GO:BP	regulation of miRNA transcription	16175	22593	GO:00063….
query_1	TRUE	0.0481013	100	912	12	0.0131579	0.1200000	GO:0060348	GO:BP	bone development	16175	14559	GO:00015….
query_1	TRUE	0.0485393	16	912	4	0.0043860	0.2500000	GO:0043031	GO:BP	negative regulation of macrophage activation	16175	10486	GO:00026….
query_1	TRUE	0.0485393	16	912	4	0.0043860	0.2500000	GO:0002756	GO:BP	MyD88-independent toll-like receptor signaling pathway	16175	1267	GO:0002224
query_1	TRUE	0.0485393	16	912	4	0.0043860	0.2500000	GO:0060143	GO:BP	positive regulation of syncytium formation by plasma membrane fusion	16175	14387	GO:00007….
query_1	TRUE	0.0485393	16	912	4	0.0043860	0.2500000	GO:0009164	GO:BP	nucleoside catabolic process	16175	3330	GO:00091….
query_1	TRUE	0.0485393	16	912	4	0.0043860	0.2500000	GO:0050765	GO:BP	negative regulation of phagocytosis	16175	13239	GO:00069….
query_1	TRUE	0.0493956	125	912	14	0.0153509	0.1120000	GO:1903169	GO:BP	regulation of calcium ion transmembrane transport	16175	22802	GO:00519….
query_1	TRUE	0.0498311	44	912	7	0.0076754	0.1590909	GO:0030195	GO:BP	negative regulation of blood coagulation	16175	6706	GO:00075….
query_1	TRUE	0.0498311	44	912	7	0.0076754	0.1590909	GO:1900047	GO:BP	negative regulation of hemostasis	16175	20349	GO:00075….
query_1	TRUE	0.0498311	44	912	7	0.0076754	0.1590909	GO:0140467	GO:BP	integrated stress response signaling	16175	19788	GO:00335….
query_1	TRUE	0.0499663	34	912	6	0.0065789	0.1764706	GO:0010573	GO:BP	vascular endothelial growth factor production	16175	4226	GO:0001816
query_1	TRUE	0.0000000	171	935	82	0.0877005	0.4795322	GO:0003823	GO:MF	antigen binding	17327	364	GO:0005488
query_1	TRUE	0.0000000	139	935	56	0.0598930	0.4028777	GO:0140375	GO:MF	immune receptor activity	17327	9378	GO:0038023
query_1	TRUE	0.0000000	1373	935	180	0.1925134	0.1310998	GO:0060089	GO:MF	molecular transducer activity	17327	7796	GO:0003674
query_1	TRUE	0.0000000	1373	935	180	0.1925134	0.1310998	GO:0038023	GO:MF	signaling receptor activity	17327	5035	GO:0060089
query_1	TRUE	0.0000000	1291	935	163	0.1743316	0.1262587	GO:0005102	GO:MF	signaling receptor binding	17327	1258	GO:0005515
query_1	TRUE	0.0000000	1152	935	140	0.1497326	0.1215278	GO:0004888	GO:MF	transmembrane signaling receptor activity	17327	1126	GO:0038023
query_1	TRUE	0.0000000	139	935	40	0.0427807	0.2877698	GO:0019955	GO:MF	cytokine binding	17327	3516	GO:0005515
query_1	TRUE	0.0000000	96	935	32	0.0342246	0.3333333	GO:0004896	GO:MF	cytokine receptor activity	17327	1129	GO:00048….
query_1	TRUE	0.0000000	41	935	17	0.0181818	0.4146341	GO:0042605	GO:MF	peptide antigen binding	17327	5152	GO:00038….
query_1	TRUE	0.0000000	32	935	15	0.0160428	0.4687500	GO:0023023	GO:MF	MHC protein complex binding	17327	3591	GO:0044877
query_1	TRUE	0.0000000	33	935	15	0.0160428	0.4545455	GO:0019956	GO:MF	chemokine binding	17327	3517	GO:0019955
query_1	TRUE	0.0000000	48	935	17	0.0181818	0.3541667	GO:0008009	GO:MF	chemokine activity	17327	1498	GO:00051….
query_1	TRUE	0.0000001	1013	935	102	0.1090909	0.1006910	GO:0044877	GO:MF	protein-containing complex binding	17327	5554	GO:0005488
query_1	TRUE	0.0000001	24	935	12	0.0128342	0.5000000	GO:0019957	GO:MF	C-C chemokine binding	17327	3518	GO:0019956
query_1	TRUE	0.0000001	72	935	20	0.0213904	0.2777778	GO:0042379	GO:MF	chemokine receptor binding	17327	5133	GO:00016….
query_1	TRUE	0.0000001	24	935	12	0.0128342	0.5000000	GO:0023026	GO:MF	MHC class II protein complex binding	17327	3594	GO:0023023
query_1	TRUE	0.0000002	21	935	11	0.0117647	0.5238095	GO:0033691	GO:MF	sialic acid binding	17327	4377	GO:00314….
query_1	TRUE	0.0000002	10	935	8	0.0085561	0.8000000	GO:0019763	GO:MF	immunoglobulin receptor activity	17327	3450	GO:00048….
query_1	TRUE	0.0000003	235	935	37	0.0395722	0.1574468	GO:0005126	GO:MF	cytokine receptor binding	17327	1275	GO:0005102
query_1	TRUE	0.0000003	51	935	16	0.0171123	0.3137255	GO:0015026	GO:MF	coreceptor activity	17327	2240	GO:0038023
query_1	TRUE	0.0000003	18	935	10	0.0106952	0.5555556	GO:0019865	GO:MF	immunoglobulin binding	17327	3496	GO:0044877
query_1	TRUE	0.0000004	23	935	11	0.0117647	0.4782609	GO:0016493	GO:MF	C-C chemokine receptor activity	17327	2766	GO:0004950
query_1	TRUE	0.0000007	35	935	13	0.0139037	0.3714286	GO:0042287	GO:MF	MHC protein binding	17327	5116	GO:0005102
query_1	TRUE	0.0000007	814	935	83	0.0887701	0.1019656	GO:0097367	GO:MF	carbohydrate derivative binding	17327	8493	GO:0005488
query_1	TRUE	0.0000008	110	935	23	0.0245989	0.2090909	GO:0030246	GO:MF	carbohydrate binding	17327	3633	GO:0005488
query_1	TRUE	0.0000014	31	935	12	0.0128342	0.3870968	GO:0038187	GO:MF	pattern recognition receptor activity	17327	5062	GO:0038023
query_1	TRUE	0.0000017	26	935	11	0.0117647	0.4230769	GO:0001637	GO:MF	G protein-coupled chemoattractant receptor activity	17327	222	GO:0004930
query_1	TRUE	0.0000017	26	935	11	0.0117647	0.4230769	GO:0004950	GO:MF	chemokine receptor activity	17327	1171	GO:00016….
query_1	TRUE	0.0000023	226	935	34	0.0363636	0.1504425	GO:0042277	GO:MF	peptide binding	17327	5109	GO:0005488
query_1	TRUE	0.0000055	10	935	7	0.0074866	0.7000000	GO:0071723	GO:MF	lipopeptide binding	17327	8196	GO:00082….
query_1	TRUE	0.0000061	14	935	8	0.0085561	0.5714286	GO:0034987	GO:MF	immunoglobulin receptor binding	17327	4800	GO:0005102
query_1	TRUE	0.0000066	143	935	25	0.0267380	0.1748252	GO:0005178	GO:MF	integrin binding	17327	1322	GO:00051….
query_1	TRUE	0.0000079	185	935	29	0.0310160	0.1567568	GO:0005125	GO:MF	cytokine activity	17327	1274	GO:0048018
query_1	TRUE	0.0000116	1934	935	154	0.1647059	0.0796277	GO:0042802	GO:MF	identical protein binding	17327	5171	GO:0005515
query_1	TRUE	0.0000123	11	935	7	0.0074866	0.6363636	GO:0032393	GO:MF	MHC class I receptor activity	17327	4188	GO:00048….
query_1	TRUE	0.0000305	373	935	44	0.0470588	0.1179625	GO:0004930	GO:MF	G protein-coupled receptor activity	17327	1154	GO:0004888
query_1	TRUE	0.0000328	48	935	13	0.0139037	0.2708333	GO:0048020	GO:MF	CCR chemokine receptor binding	17327	6730	GO:0042379
query_1	TRUE	0.0000350	17	935	8	0.0085561	0.4705882	GO:0001614	GO:MF	purinergic nucleotide receptor activity	17327	213	GO:0016502
query_1	TRUE	0.0000721	76	935	16	0.0171123	0.2105263	GO:0001540	GO:MF	amyloid-beta binding	17327	194	GO:00332….
query_1	TRUE	0.0000938	19	935	8	0.0085561	0.4210526	GO:0016502	GO:MF	nucleotide receptor activity	17327	2775	GO:0004888
query_1	TRUE	0.0001251	10	935	6	0.0064171	0.6000000	GO:0045028	GO:MF	G protein-coupled purinergic nucleotide receptor activity	17327	5557	GO:00016….
query_1	TRUE	0.0001329	664	935	64	0.0684492	0.0963855	GO:0008289	GO:MF	lipid binding	17327	1623	GO:0005488
query_1	TRUE	0.0002447	7	935	5	0.0053476	0.7142857	GO:0032396	GO:MF	inhibitory MHC class I receptor activity	17327	4191	GO:0032393
query_1	TRUE	0.0002927	436	935	46	0.0491979	0.1055046	GO:0030545	GO:MF	signaling receptor regulator activity	17327	3712	GO:0098772
query_1	TRUE	0.0002927	397	935	43	0.0459893	0.1083123	GO:0048018	GO:MF	receptor ligand activity	17327	6728	GO:00051….
query_1	TRUE	0.0003900	402	935	43	0.0459893	0.1069652	GO:0030546	GO:MF	signaling receptor activator activity	17327	3713	GO:00305….
query_1	TRUE	0.0004719	37	935	10	0.0106952	0.2702703	GO:0004715	GO:MF	non-membrane spanning protein tyrosine kinase activity	17327	986	GO:0004713
query_1	TRUE	0.0005584	8	935	5	0.0053476	0.6250000	GO:0032395	GO:MF	MHC class II receptor activity	17327	4190	GO:00048….
query_1	TRUE	0.0007420	166	935	23	0.0245989	0.1385542	GO:0005201	GO:MF	extracellular matrix structural constituent	17327	1331	GO:0005198
query_1	TRUE	0.0008278	262	935	31	0.0331551	0.1183206	GO:0001664	GO:MF	G protein-coupled receptor binding	17327	231	GO:0005102
query_1	TRUE	0.0010661	126	935	19	0.0203209	0.1507937	GO:0002020	GO:MF	protease binding	17327	287	GO:0019899
query_1	TRUE	0.0012653	332	935	36	0.0385027	0.1084337	GO:0003779	GO:MF	actin binding	17327	358	GO:0008092
query_1	TRUE	0.0015023	930	935	78	0.0834225	0.0838710	GO:0140677	GO:MF	molecular function activator activity	17327	9477	GO:0098772
query_1	TRUE	0.0019150	213	935	26	0.0278075	0.1220657	GO:0033218	GO:MF	amide binding	17327	4278	GO:0005488
query_1	TRUE	0.0020019	10	935	5	0.0053476	0.5000000	GO:0005031	GO:MF	tumor necrosis factor receptor activity	17327	1233	GO:0005035
query_1	TRUE	0.0025060	6	935	4	0.0042781	0.6666667	GO:0023029	GO:MF	MHC class Ib protein binding	17327	3597	GO:0042287
query_1	TRUE	0.0029226	11	935	5	0.0053476	0.4545455	GO:0001851	GO:MF	complement component C3b binding	17327	258	GO:00018….
query_1	TRUE	0.0029226	3	935	3	0.0032086	1.0000000	GO:0019767	GO:MF	IgE receptor activity	17327	3452	GO:0019763
query_1	TRUE	0.0029226	3	935	3	0.0032086	1.0000000	GO:0004911	GO:MF	interleukin-2 receptor activity	17327	1141	GO:0004896
query_1	TRUE	0.0029226	3	935	3	0.0032086	1.0000000	GO:0001791	GO:MF	IgM binding	17327	250	GO:0019865
query_1	TRUE	0.0029226	3	935	3	0.0032086	1.0000000	GO:0019976	GO:MF	interleukin-2 binding	17327	3531	GO:00198….
query_1	TRUE	0.0029226	126	935	18	0.0192513	0.1428571	GO:0004252	GO:MF	serine-type endopeptidase activity	17327	653	GO:00041….
query_1	TRUE	0.0029226	11	935	5	0.0053476	0.4545455	GO:0042608	GO:MF	T cell receptor binding	17327	5153	GO:00051….
query_1	TRUE	0.0029226	3	935	3	0.0032086	1.0000000	GO:0042010	GO:MF	interleukin-15 receptor activity	17327	5075	GO:0004896
query_1	TRUE	0.0029226	3	935	3	0.0032086	1.0000000	GO:0019770	GO:MF	IgG receptor activity	17327	3455	GO:0019763
query_1	TRUE	0.0029226	11	935	5	0.0053476	0.4545455	GO:0035325	GO:MF	Toll-like receptor binding	17327	4838	GO:0005102
query_1	TRUE	0.0031099	162	935	21	0.0224599	0.1296296	GO:0005539	GO:MF	glycosaminoglycan binding	17327	1487	GO:0097367
query_1	TRUE	0.0039116	15314	935	859	0.9187166	0.0560925	GO:0005488	GO:MF	binding	17327	1460	GO:0003674
query_1	TRUE	0.0039403	40	935	9	0.0096257	0.2250000	GO:0001784	GO:MF	phosphotyrosine residue binding	17327	246	GO:0045309
query_1	TRUE	0.0043287	12	935	5	0.0053476	0.4166667	GO:0004126	GO:MF	cytidine deaminase activity	17327	598	GO:00168….
query_1	TRUE	0.0043287	18	935	6	0.0064171	0.3333333	GO:0045236	GO:MF	CXCR chemokine receptor binding	17327	5581	GO:0042379
query_1	TRUE	0.0043287	7	935	4	0.0042781	0.5714286	GO:0042289	GO:MF	MHC class II protein binding	17327	5118	GO:0042287
query_1	TRUE	0.0043287	7	935	4	0.0042781	0.5714286	GO:0046977	GO:MF	TAP binding	17327	5767	GO:0005515
query_1	TRUE	0.0061337	1745	935	126	0.1347594	0.0722063	GO:0098772	GO:MF	molecular function regulator activity	17327	8575	GO:0003674
query_1	TRUE	0.0065430	13	935	5	0.0053476	0.3846154	GO:0005035	GO:MF	death receptor activity	17327	1235	GO:0004888
query_1	TRUE	0.0071211	27	935	7	0.0074866	0.2592593	GO:0016814	GO:MF	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	17327	2950	GO:0016810
query_1	TRUE	0.0077928	8	935	4	0.0042781	0.5000000	GO:0042609	GO:MF	CD4 receptor binding	17327	5154	GO:0005102
query_1	TRUE	0.0091103	4	935	3	0.0032086	0.7500000	GO:0035663	GO:MF	Toll-like receptor 2 binding	17327	4894	GO:0035325
query_1	TRUE	0.0091103	4	935	3	0.0032086	0.7500000	GO:0046978	GO:MF	TAP1 binding	17327	5768	GO:0046977
query_1	TRUE	0.0091103	118	935	16	0.0171123	0.1355932	GO:0004713	GO:MF	protein tyrosine kinase activity	17327	984	GO:0004672
query_1	TRUE	0.0097961	21	935	6	0.0064171	0.2857143	GO:0001846	GO:MF	opsonin binding	17327	253	GO:0005515
query_1	TRUE	0.0127558	15	935	5	0.0053476	0.3333333	GO:0070492	GO:MF	oligosaccharide binding	17327	8075	GO:0030246
query_1	TRUE	0.0152405	148	935	18	0.0192513	0.1216216	GO:0008236	GO:MF	serine-type peptidase activity	17327	1596	GO:00082….
query_1	TRUE	0.0154306	31	935	7	0.0074866	0.2258065	GO:0019239	GO:MF	deaminase activity	17327	3442	GO:0016810
query_1	TRUE	0.0154306	680	935	56	0.0598930	0.0823529	GO:0042803	GO:MF	protein homodimerization activity	17327	5172	GO:00428….
query_1	TRUE	0.0154306	31	935	7	0.0074866	0.2258065	GO:0042169	GO:MF	SH2 domain binding	17327	5105	GO:0019904
query_1	TRUE	0.0160658	174	935	20	0.0213904	0.1149425	GO:0061134	GO:MF	peptidase regulator activity	17327	7812	GO:0030234
query_1	TRUE	0.0165257	16	935	5	0.0053476	0.3125000	GO:0042834	GO:MF	peptidoglycan binding	17327	5178	GO:0005539
query_1	TRUE	0.0167886	138	935	17	0.0181818	0.1231884	GO:0061135	GO:MF	endopeptidase regulator activity	17327	7813	GO:0061134
query_1	TRUE	0.0174874	5	935	3	0.0032086	0.6000000	GO:0030883	GO:MF	endogenous lipid antigen binding	17327	3834	GO:0030882
query_1	TRUE	0.0174874	5	935	3	0.0032086	0.6000000	GO:0030884	GO:MF	exogenous lipid antigen binding	17327	3835	GO:0030882
query_1	TRUE	0.0174874	5	935	3	0.0032086	0.6000000	GO:0051373	GO:MF	FATZ binding	17327	7444	GO:0008092
query_1	TRUE	0.0174874	10	935	4	0.0042781	0.4000000	GO:0008330	GO:MF	protein tyrosine/threonine phosphatase activity	17327	1639	GO:0004721
query_1	TRUE	0.0174874	151	935	18	0.0192513	0.1192053	GO:0017171	GO:MF	serine hydrolase activity	17327	3121	GO:0016787
query_1	TRUE	0.0174874	5	935	3	0.0032086	0.6000000	GO:0048248	GO:MF	CXCR3 chemokine receptor binding	17327	6744	GO:0045236
query_1	TRUE	0.0174874	5	935	3	0.0032086	0.6000000	GO:0030882	GO:MF	lipid antigen binding	17327	3833	GO:00038….
query_1	TRUE	0.0174874	10	935	4	0.0042781	0.4000000	GO:0033550	GO:MF	MAP kinase tyrosine phosphatase activity	17327	4365	GO:00047….
query_1	TRUE	0.0174874	5	935	3	0.0032086	0.6000000	GO:0001875	GO:MF	lipopolysaccharide immune receptor activity	17327	275	GO:0038187
query_1	TRUE	0.0174874	5	935	3	0.0032086	0.6000000	GO:0031730	GO:MF	CCR5 chemokine receptor binding	17327	3967	GO:0048020
query_1	TRUE	0.0174874	10	935	4	0.0042781	0.4000000	GO:0017017	GO:MF	MAP kinase tyrosine/serine/threonine phosphatase activity	17327	3058	GO:00081….
query_1	TRUE	0.0202800	52	935	9	0.0096257	0.1730769	GO:0045309	GO:MF	protein phosphorylated amino acid binding	17327	5593	GO:0051219
query_1	TRUE	0.0208964	25	935	6	0.0064171	0.2400000	GO:0001618	GO:MF	virus receptor activity	17327	215	GO:0140272
query_1	TRUE	0.0208964	25	935	6	0.0064171	0.2400000	GO:0001848	GO:MF	complement binding	17327	255	GO:0005515
query_1	TRUE	0.0213636	960	935	73	0.0780749	0.0760417	GO:0043168	GO:MF	anion binding	17327	5249	GO:0043167
query_1	TRUE	0.0244518	145	935	17	0.0181818	0.1172414	GO:0031406	GO:MF	carboxylic acid binding	17327	3887	GO:00431….
query_1	TRUE	0.0270494	110	935	14	0.0149733	0.1272727	GO:0008201	GO:MF	heparin binding	17327	1590	GO:00055….
query_1	TRUE	0.0286394	55	935	9	0.0096257	0.1636364	GO:0038024	GO:MF	cargo receptor activity	17327	5036	GO:0003674
query_1	TRUE	0.0303770	27	935	6	0.0064171	0.2222222	GO:0140272	GO:MF	exogenous protein binding	17327	9338	GO:0005515
query_1	TRUE	0.0303936	6	935	3	0.0032086	0.5000000	GO:0031726	GO:MF	CCR1 chemokine receptor binding	17327	3963	GO:0048020
query_1	TRUE	0.0303936	2	935	2	0.0021390	1.0000000	GO:0031732	GO:MF	CCR7 chemokine receptor binding	17327	3969	GO:0048020
query_1	TRUE	0.0303936	2	935	2	0.0021390	1.0000000	GO:0042008	GO:MF	interleukin-18 receptor activity	17327	5073	GO:0004896
query_1	TRUE	0.0303936	2	935	2	0.0021390	1.0000000	GO:0070080	GO:MF	titin Z domain binding	17327	8021	GO:0019904
query_1	TRUE	0.0303936	2	935	2	0.0021390	1.0000000	GO:0004917	GO:MF	interleukin-7 receptor activity	17327	1146	GO:0004896
query_1	TRUE	0.0303936	2	935	2	0.0021390	1.0000000	GO:0019772	GO:MF	low-affinity IgG receptor activity	17327	3457	GO:0019770
query_1	TRUE	0.0303936	2	935	2	0.0021390	1.0000000	GO:0015433	GO:MF	ABC-type peptide antigen transporter activity	17327	2504	GO:0015440
query_1	TRUE	0.0303936	2	935	2	0.0021390	1.0000000	GO:0004666	GO:MF	prostaglandin-endoperoxide synthase activity	17327	953	GO:0016705
query_1	TRUE	0.0304765	12	935	4	0.0042781	0.3333333	GO:0097493	GO:MF	structural molecule activity conferring elasticity	17327	8500	GO:0005198
query_1	TRUE	0.0319044	326	935	30	0.0320856	0.0920245	GO:0004175	GO:MF	endopeptidase activity	17327	642	GO:0008233
query_1	TRUE	0.0407639	13	935	4	0.0042781	0.3076923	GO:0031432	GO:MF	titin binding	17327	3893	GO:0008092
query_1	TRUE	0.0407639	13	935	4	0.0042781	0.3076923	GO:0042288	GO:MF	MHC class I protein binding	17327	5117	GO:0042287
query_1	TRUE	0.0407639	13	935	4	0.0042781	0.3076923	GO:0089720	GO:MF	caspase binding	17327	8369	GO:0002020
query_1	TRUE	0.0451194	7	935	3	0.0032086	0.4285714	GO:0043120	GO:MF	tumor necrosis factor binding	17327	5240	GO:0019955
query_1	TRUE	0.0451194	7	935	3	0.0032086	0.4285714	GO:0005021	GO:MF	vascular endothelial growth factor receptor activity	17327	1228	GO:0004714
query_1	TRUE	0.0451194	7	935	3	0.0032086	0.4285714	GO:0031433	GO:MF	telethonin binding	17327	3894	GO:0008092
query_1	TRUE	0.0451194	156	935	17	0.0181818	0.1089744	GO:0043177	GO:MF	organic acid binding	17327	5253	GO:0036094
query_1	TRUE	0.0489703	40	935	7	0.0074866	0.1750000	GO:0043028	GO:MF	cysteine-type endopeptidase regulator activity involved in apoptotic process	17327	5235	GO:0030234
query_1	TRUE	0.0000000	92	514	39	0.0758755	0.4239130	KEGG:04640	KEGG	Hematopoietic cell lineage	8484	333	KEGG:00000
query_1	TRUE	0.0000000	291	514	69	0.1342412	0.2371134	KEGG:04060	KEGG	Cytokine-cytokine receptor interaction	8484	253	KEGG:00000
query_1	TRUE	0.0000000	98	514	37	0.0719844	0.3775510	KEGG:04061	KEGG	Viral protein interaction with cytokine and cytokine receptor	8484	254	KEGG:00000
query_1	TRUE	0.0000000	153	514	45	0.0875486	0.2941176	KEGG:04514	KEGG	Cell adhesion molecules	8484	315	KEGG:00000
query_1	TRUE	0.0000000	86	514	32	0.0622568	0.3720930	KEGG:05150	KEGG	Staphylococcus aureus infection	8484	439	KEGG:00000
query_1	TRUE	0.0000000	190	514	47	0.0914397	0.2473684	KEGG:04062	KEGG	Chemokine signaling pathway	8484	255	KEGG:00000
query_1	TRUE	0.0000000	72	514	28	0.0544747	0.3888889	KEGG:05140	KEGG	Leishmaniasis	8484	433	KEGG:00000
query_1	TRUE	0.0000000	147	514	39	0.0758755	0.2653061	KEGG:04145	KEGG	Phagosome	8484	281	KEGG:00000
query_1	TRUE	0.0000000	37	514	20	0.0389105	0.5405405	KEGG:05332	KEGG	Graft-versus-host disease	8484	487	KEGG:00000
query_1	TRUE	0.0000000	37	514	20	0.0389105	0.5405405	KEGG:05340	KEGG	Primary immunodeficiency	8484	488	KEGG:00000
query_1	TRUE	0.0000000	34	514	19	0.0369650	0.5588235	KEGG:05330	KEGG	Allograft rejection	8484	486	KEGG:00000
query_1	TRUE	0.0000000	132	514	36	0.0700389	0.2727273	KEGG:04380	KEGG	Osteoclast differentiation	8484	309	KEGG:00000
query_1	TRUE	0.0000000	40	514	19	0.0369650	0.4750000	KEGG:04940	KEGG	Type I diabetes mellitus	8484	394	KEGG:00000
query_1	TRUE	0.0000000	175	514	39	0.0758755	0.2228571	KEGG:05152	KEGG	Tuberculosis	8484	440	KEGG:00000
query_1	TRUE	0.0000000	105	514	29	0.0564202	0.2761905	KEGG:04659	KEGG	Th17 cell differentiation	8484	337	KEGG:00000
query_1	TRUE	0.0000000	62	514	22	0.0428016	0.3548387	KEGG:05321	KEGG	Inflammatory bowel disease	8484	483	KEGG:00000
query_1	TRUE	0.0000000	102	514	28	0.0544747	0.2745098	KEGG:04064	KEGG	NF-kappa B signaling pathway	8484	256	KEGG:00000
query_1	TRUE	0.0000000	88	514	26	0.0505837	0.2954545	KEGG:05323	KEGG	Rheumatoid arthritis	8484	485	KEGG:00000
query_1	TRUE	0.0000000	69	514	23	0.0447471	0.3333333	KEGG:04612	KEGG	Antigen processing and presentation	8484	322	KEGG:00000
query_1	TRUE	0.0000000	124	514	31	0.0603113	0.2500000	KEGG:04650	KEGG	Natural killer cell mediated cytotoxicity	8484	334	KEGG:00000
query_1	TRUE	0.0000000	89	514	26	0.0505837	0.2921348	KEGG:04658	KEGG	Th1 and Th2 cell differentiation	8484	336	KEGG:00000
query_1	TRUE	0.0000000	49	514	19	0.0369650	0.3877551	KEGG:05320	KEGG	Autoimmune thyroid disease	8484	482	KEGG:00000
query_1	TRUE	0.0000000	81	514	24	0.0466926	0.2962963	KEGG:04662	KEGG	B cell receptor signaling pathway	8484	339	KEGG:00000
query_1	TRUE	0.0000000	27	514	14	0.0272374	0.5185185	KEGG:05310	KEGG	Asthma	8484	481	KEGG:00000
query_1	TRUE	0.0000000	198	514	36	0.0700389	0.1818182	KEGG:05169	KEGG	Epstein-Barr virus infection	8484	450	KEGG:00000
query_1	TRUE	0.0000000	44	514	16	0.0311284	0.3636364	KEGG:04672	KEGG	Intestinal immune network for IgA production	8484	344	KEGG:00000
query_1	TRUE	0.0000000	63	514	19	0.0369650	0.3015873	KEGG:05416	KEGG	Viral myocarditis	8484	493	KEGG:00000
query_1	TRUE	0.0000000	86	514	22	0.0428016	0.2558140	KEGG:04610	KEGG	Complement and coagulation cascades	8484	320	KEGG:00000
query_1	TRUE	0.0000001	113	514	25	0.0486381	0.2212389	KEGG:04668	KEGG	TNF signaling pathway	8484	342	KEGG:00000
query_1	TRUE	0.0000001	76	514	20	0.0389105	0.2631579	KEGG:05133	KEGG	Pertussis	8484	430	KEGG:00000
query_1	TRUE	0.0000001	49	514	16	0.0311284	0.3265306	KEGG:05144	KEGG	Malaria	8484	436	KEGG:00000
query_1	TRUE	0.0000002	108	514	24	0.0466926	0.2222222	KEGG:05145	KEGG	Toxoplasmosis	8484	437	KEGG:00000
query_1	TRUE	0.0000003	182	514	32	0.0622568	0.1758242	KEGG:04621	KEGG	NOD-like receptor signaling pathway	8484	326	KEGG:00000
query_1	TRUE	0.0000008	218	514	35	0.0680934	0.1605505	KEGG:05166	KEGG	Human T-cell leukemia virus 1 infection	8484	447	KEGG:00000
query_1	TRUE	0.0000018	167	514	29	0.0564202	0.1736527	KEGG:05164	KEGG	Influenza A	8484	445	KEGG:00000
query_1	TRUE	0.0000022	132	514	25	0.0486381	0.1893939	KEGG:05322	KEGG	Systemic lupus erythematosus	8484	484	KEGG:00000
query_1	TRUE	0.0000084	210	514	32	0.0622568	0.1523810	KEGG:05170	KEGG	Human immunodeficiency virus 1 infection	8484	451	KEGG:00000
query_1	TRUE	0.0000157	101	514	20	0.0389105	0.1980198	KEGG:05142	KEGG	Chagas disease	8484	434	KEGG:00000
query_1	TRUE	0.0000160	119	514	22	0.0428016	0.1848739	KEGG:04660	KEGG	T cell receptor signaling pathway	8484	338	KEGG:00000
query_1	TRUE	0.0000194	188	514	29	0.0564202	0.1542553	KEGG:04613	KEGG	Neutrophil extracellular trap formation	8484	323	KEGG:00000
query_1	TRUE	0.0000293	56	514	14	0.0272374	0.2500000	KEGG:05134	KEGG	Legionellosis	8484	431	KEGG:00000
query_1	TRUE	0.0000324	214	514	31	0.0603113	0.1448598	KEGG:05417	KEGG	Lipid and atherosclerosis	8484	494	KEGG:00000
query_1	TRUE	0.0000369	36	514	11	0.0214008	0.3055556	KEGG:05143	KEGG	African trypanosomiasis	8484	435	KEGG:00000
query_1	TRUE	0.0000522	138	514	23	0.0447471	0.1666667	KEGG:05162	KEGG	Measles	8484	443	KEGG:00000
query_1	TRUE	0.0000819	104	514	19	0.0369650	0.1826923	KEGG:04625	KEGG	C-type lectin receptor signaling pathway	8484	330	KEGG:00000
query_1	TRUE	0.0000892	114	514	20	0.0389105	0.1754386	KEGG:04670	KEGG	Leukocyte transendothelial migration	8484	343	KEGG:00000
query_1	TRUE	0.0001222	89	514	17	0.0330739	0.1910112	KEGG:05235	KEGG	PD-L1 expression and PD-1 checkpoint pathway in cancer	8484	480	KEGG:00000
query_1	TRUE	0.0001225	136	514	22	0.0428016	0.1617647	KEGG:05135	KEGG	Yersinia infection	8484	432	KEGG:00000
query_1	TRUE	0.0001731	223	514	30	0.0583658	0.1345291	KEGG:05163	KEGG	Human cytomegalovirus infection	8484	444	KEGG:00000
query_1	TRUE	0.0001764	101	514	18	0.0350195	0.1782178	KEGG:05146	KEGG	Amoebiasis	8484	438	KEGG:00000
query_1	TRUE	0.0002196	162	514	24	0.0466926	0.1481481	KEGG:04630	KEGG	JAK-STAT signaling pathway	8484	332	KEGG:00000
query_1	TRUE	0.0002236	194	514	27	0.0525292	0.1391753	KEGG:05167	KEGG	Kaposi sarcoma-associated herpesvirus infection	8484	448	KEGG:00000
query_1	TRUE	0.0003239	156	514	23	0.0447471	0.1474359	KEGG:04148	KEGG	Efferocytosis	8484	283	KEGG:00000
query_1	TRUE	0.0003239	106	514	18	0.0350195	0.1698113	KEGG:04620	KEGG	Toll-like receptor signaling pathway	8484	325	KEGG:00000
query_1	TRUE	0.0003367	5	514	4	0.0077821	0.8000000	KEGG:03260	KEGG	Virion - Human immunodeficiency virus	8484	226	KEGG:00000
query_1	TRUE	0.0004596	192	514	26	0.0505837	0.1354167	KEGG:05202	KEGG	Transcriptional misregulation in cancer	8484	454	KEGG:00000
query_1	TRUE	0.0005184	82	514	15	0.0291829	0.1829268	KEGG:04623	KEGG	Cytosolic DNA-sensing pathway	8484	328	KEGG:00000
query_1	TRUE	0.0016439	231	514	28	0.0544747	0.1212121	KEGG:05171	KEGG	Coronavirus disease - COVID-19	8484	452	KEGG:00000
query_1	TRUE	0.0030005	96	514	15	0.0291829	0.1562500	KEGG:04666	KEGG	Fc gamma R-mediated phagocytosis	8484	341	KEGG:00000
query_1	TRUE	0.0044272	527	514	50	0.0972763	0.0948767	KEGG:05200	KEGG	Pathways in cancer	8484	453	KEGG:00000
query_1	TRUE	0.0057056	92	514	14	0.0272374	0.1521739	KEGG:04657	KEGG	IL-17 signaling pathway	8484	335	KEGG:00000
query_1	TRUE	0.0075387	356	514	36	0.0700389	0.1011236	KEGG:04151	KEGG	PI3K-Akt signaling pathway	8484	285	KEGG:00000
query_1	TRUE	0.0089948	210	514	24	0.0466926	0.1142857	KEGG:04015	KEGG	Rap1 signaling pathway	8484	248	KEGG:00000
query_1	TRUE	0.0096195	67	514	11	0.0214008	0.1641791	KEGG:04664	KEGG	Fc epsilon RI signaling pathway	8484	340	KEGG:00000
query_1	TRUE	0.0144653	124	514	16	0.0311284	0.1290323	KEGG:04611	KEGG	Platelet activation	8484	321	KEGG:00000
query_1	TRUE	0.0167613	62	514	10	0.0194553	0.1612903	KEGG:03250	KEGG	Viral life cycle - HIV-1	8484	223	KEGG:00000
query_1	TRUE	0.0290637	67	514	10	0.0194553	0.1492537	KEGG:05221	KEGG	Acute myeloid leukemia	8484	472	KEGG:00000
query_1	TRUE	0.0409259	251	514	25	0.0486381	0.0996016	KEGG:04020	KEGG	Calcium signaling pathway	8484	250	KEGG:00000

Upregulated Gene Set

gprofiler_output <- gprofiler2::gost(query = upregulated_genes, 
                                     significant = TRUE,
                                     exclude_iea = TRUE,
                                     correction_method = "fdr", 
                                     organism = "hsapiens", 
                                     source = c("GO:MF", "GO:BP", "KEGG"))

gprofiler_up <- as.data.frame(gprofiler_output$result)
knitr::kable(gprofiler_up, type="html") %>% 
  kableExtra::scroll_box(width = "600px", height = "200px")

query	significant	p_value	term_size	query_size	intersection_size	precision	recall	term_id	source	term_name	effective_domain_size	source_order	parents
query_1	TRUE	0.0000000	2117	887	441	0.4971815	0.2083137	GO:0002376	GO:BP	immune system process	16175	906	GO:0008150
query_1	TRUE	0.0000000	1519	887	374	0.4216460	0.2462146	GO:0006955	GO:BP	immune response	16175	2586	GO:00023….
query_1	TRUE	0.0000000	1238	887	272	0.3066516	0.2197092	GO:0002682	GO:BP	regulation of immune system process	16175	1200	GO:00023….
query_1	TRUE	0.0000000	699	887	202	0.2277339	0.2889843	GO:0045321	GO:BP	leukocyte activation	16175	11356	GO:00017….
query_1	TRUE	0.0000000	820	887	218	0.2457723	0.2658537	GO:0001775	GO:BP	cell activation	16175	440	GO:00099….
query_1	TRUE	0.0000000	881	887	217	0.2446449	0.2463110	GO:0002684	GO:BP	positive regulation of immune system process	16175	1202	GO:00023….
query_1	TRUE	0.0000000	1364	887	267	0.3010147	0.1957478	GO:0006952	GO:BP	defense response	16175	2583	GO:0006950
query_1	TRUE	0.0000000	756	887	196	0.2209696	0.2592593	GO:0050776	GO:BP	regulation of immune response	16175	13250	GO:00026….
query_1	TRUE	0.0000000	569	887	169	0.1905299	0.2970123	GO:0046649	GO:BP	lymphocyte activation	16175	12286	GO:0045321
query_1	TRUE	0.0000000	536	887	158	0.1781285	0.2947761	GO:0002252	GO:BP	immune effector process	16175	784	GO:0002376
query_1	TRUE	0.0000000	627	887	167	0.1882751	0.2663477	GO:0050778	GO:BP	positive regulation of immune response	16175	13252	GO:00026….
query_1	TRUE	0.0000000	7207	887	647	0.7294250	0.0897738	GO:0050896	GO:BP	response to stimulus	16175	13339	GO:0008150
query_1	TRUE	0.0000000	468	887	141	0.1589628	0.3012821	GO:0050865	GO:BP	regulation of cell activation	16175	13313	GO:00017….
query_1	TRUE	0.0000000	421	887	131	0.1476888	0.3111639	GO:0002694	GO:BP	regulation of leukocyte activation	16175	1212	GO:00026….
query_1	TRUE	0.0000000	406	887	126	0.1420519	0.3103448	GO:0042110	GO:BP	T cell activation	16175	9970	GO:0046649
query_1	TRUE	0.0000000	334	887	114	0.1285231	0.3413174	GO:0002250	GO:BP	adaptive immune response	16175	782	GO:0006955
query_1	TRUE	0.0000000	475	887	132	0.1488162	0.2778947	GO:0002253	GO:BP	activation of immune response	16175	785	GO:00023….
query_1	TRUE	0.0000000	369	887	116	0.1307779	0.3143631	GO:0051249	GO:BP	regulation of lymphocyte activation	16175	13596	GO:00026….
query_1	TRUE	0.0000000	334	887	109	0.1228861	0.3263473	GO:0002443	GO:BP	leukocyte mediated immunity	16175	966	GO:0002252
query_1	TRUE	0.0000000	1724	887	257	0.2897407	0.1490719	GO:0009605	GO:BP	response to external stimulus	16175	3533	GO:0050896
query_1	TRUE	0.0000000	437	887	123	0.1386697	0.2814645	GO:0002764	GO:BP	immune response-regulating signaling pathway	16175	1275	GO:00071….
query_1	TRUE	0.0000000	1941	887	274	0.3089064	0.1411643	GO:0048584	GO:BP	positive regulation of response to stimulus	16175	12855	GO:00485….
query_1	TRUE	0.0000000	416	887	118	0.1330327	0.2836538	GO:0002757	GO:BP	immune response-activating signaling pathway	16175	1268	GO:00022….
query_1	TRUE	0.0000000	594	887	139	0.1567080	0.2340067	GO:0006954	GO:BP	inflammatory response	16175	2585	GO:0006952
query_1	TRUE	0.0000000	2272	887	295	0.3325817	0.1298415	GO:0051239	GO:BP	regulation of multicellular organismal process	16175	13589	GO:00325….
query_1	TRUE	0.0000000	276	887	95	0.1071026	0.3442029	GO:0002460	GO:BP	adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	16175	983	GO:0002250
query_1	TRUE	0.0000000	287	887	94	0.1059752	0.3275261	GO:0002768	GO:BP	immune response-regulating cell surface receptor signaling pathway	16175	1279	GO:00027….
query_1	TRUE	0.0000000	269	887	91	0.1025930	0.3382900	GO:0002449	GO:BP	lymphocyte mediated immunity	16175	972	GO:0002443
query_1	TRUE	0.0000000	265	887	90	0.1014656	0.3396226	GO:0002429	GO:BP	immune response-activating cell surface receptor signaling pathway	16175	952	GO:00027….
query_1	TRUE	0.0000000	1109	887	188	0.2119504	0.1695221	GO:0043207	GO:BP	response to external biotic stimulus	16175	10576	GO:00096….
query_1	TRUE	0.0000000	1109	887	188	0.2119504	0.1695221	GO:0051707	GO:BP	response to other organism	16175	13904	GO:00432….
query_1	TRUE	0.0000000	1143	887	191	0.2153326	0.1671041	GO:0009607	GO:BP	response to biotic stimulus	16175	3535	GO:0050896
query_1	TRUE	0.0000000	634	887	137	0.1544532	0.2160883	GO:0001817	GO:BP	regulation of cytokine production	16175	474	GO:00018….
query_1	TRUE	0.0000000	638	887	137	0.1544532	0.2147335	GO:0001816	GO:BP	cytokine production	16175	473	GO:00104….
query_1	TRUE	0.0000000	3347	887	362	0.4081172	0.1081566	GO:0048583	GO:BP	regulation of response to stimulus	16175	12854	GO:00507….
query_1	TRUE	0.0000000	934	887	167	0.1882751	0.1788009	GO:0098542	GO:BP	defense response to other organism	16175	18794	GO:00069….
query_1	TRUE	0.0000000	434	887	111	0.1251409	0.2557604	GO:0002521	GO:BP	leukocyte differentiation	16175	1043	GO:00300….
query_1	TRUE	0.0000000	324	887	96	0.1082300	0.2962963	GO:0007159	GO:BP	leukocyte cell-cell adhesion	16175	2723	GO:0098609
query_1	TRUE	0.0000000	2237	887	280	0.3156708	0.1251676	GO:0007166	GO:BP	cell surface receptor signaling pathway	16175	2730	GO:0007165
query_1	TRUE	0.0000000	855	887	158	0.1781285	0.1847953	GO:0140546	GO:BP	defense response to symbiont	16175	19820	GO:0098542
query_1	TRUE	0.0000000	1238	887	194	0.2187148	0.1567044	GO:0044419	GO:BP	biological process involved in interspecies interaction between organisms	16175	10998	GO:0008150
query_1	TRUE	0.0000000	1259	887	195	0.2198422	0.1548848	GO:0051240	GO:BP	positive regulation of multicellular organismal process	16175	13590	GO:00325….
query_1	TRUE	0.0000000	284	887	88	0.0992108	0.3098592	GO:0050863	GO:BP	regulation of T cell activation	16175	13311	GO:00421….
query_1	TRUE	0.0000000	4773	887	447	0.5039459	0.0936518	GO:0007165	GO:BP	signal transduction	16175	2729	GO:00071….
query_1	TRUE	0.0000000	290	887	87	0.0980834	0.3000000	GO:0050867	GO:BP	positive regulation of cell activation	16175	13315	GO:00017….
query_1	TRUE	0.0000000	3079	887	334	0.3765502	0.1084768	GO:0006950	GO:BP	response to stress	16175	2582	GO:0050896
query_1	TRUE	0.0000000	357	887	96	0.1082300	0.2689076	GO:1903131	GO:BP	mononuclear cell differentiation	16175	22787	GO:0002521
query_1	TRUE	0.0000000	275	887	84	0.0947012	0.3054545	GO:0002696	GO:BP	positive regulation of leukocyte activation	16175	1214	GO:00026….
query_1	TRUE	0.0000000	158	887	64	0.0721533	0.4050633	GO:0050851	GO:BP	antigen receptor-mediated signaling pathway	16175	13299	GO:0002429
query_1	TRUE	0.0000000	745	887	139	0.1567080	0.1865772	GO:0098609	GO:BP	cell-cell adhesion	16175	18805	GO:0007155
query_1	TRUE	0.0000000	884	887	153	0.1724915	0.1730769	GO:0032101	GO:BP	regulation of response to external stimulus	16175	7365	GO:00096….
query_1	TRUE	0.0000000	287	887	84	0.0947012	0.2926829	GO:1903037	GO:BP	regulation of leukocyte cell-cell adhesion	16175	22717	GO:00071….
query_1	TRUE	0.0000000	1201	887	182	0.2051860	0.1515404	GO:0007155	GO:BP	cell adhesion	16175	2719	GO:0009987
query_1	TRUE	0.0000000	386	887	97	0.1093574	0.2512953	GO:0022407	GO:BP	regulation of cell-cell adhesion	16175	6598	GO:00301….
query_1	TRUE	0.0000000	236	887	76	0.0856821	0.3220339	GO:0070661	GO:BP	leukocyte proliferation	16175	16242	GO:0008283
query_1	TRUE	0.0000000	403	887	99	0.1116122	0.2456576	GO:0001819	GO:BP	positive regulation of cytokine production	16175	476	GO:00018….
query_1	TRUE	0.0000000	638	887	126	0.1420519	0.1974922	GO:0030097	GO:BP	hemopoiesis	16175	6675	GO:0048468
query_1	TRUE	0.0000000	383	887	96	0.1082300	0.2506527	GO:0002683	GO:BP	negative regulation of immune system process	16175	1201	GO:00023….
query_1	TRUE	0.0000000	5189	887	464	0.5231116	0.0894199	GO:0007154	GO:BP	cell communication	16175	2718	GO:0009987
query_1	TRUE	0.0000000	208	887	71	0.0800451	0.3413462	GO:0046651	GO:BP	lymphocyte proliferation	16175	12287	GO:00329….
query_1	TRUE	0.0000000	5175	887	463	0.5219842	0.0894686	GO:0023052	GO:BP	signaling	16175	6640	GO:0050789
query_1	TRUE	0.0000000	211	887	71	0.0800451	0.3364929	GO:0032943	GO:BP	mononuclear cell proliferation	16175	7928	GO:0070661
query_1	TRUE	0.0000000	276	887	79	0.0890643	0.2862319	GO:0002697	GO:BP	regulation of immune effector process	16175	1215	GO:00022….
query_1	TRUE	0.0000000	249	887	75	0.0845547	0.3012048	GO:0051251	GO:BP	positive regulation of lymphocyte activation	16175	13598	GO:00026….
query_1	TRUE	0.0000000	654	887	124	0.1397971	0.1896024	GO:0031347	GO:BP	regulation of defense response	16175	7138	GO:00069….
query_1	TRUE	0.0000000	721	887	130	0.1465614	0.1803051	GO:0045087	GO:BP	innate immune response	16175	11270	GO:00069….
query_1	TRUE	0.0000000	190	887	65	0.0732807	0.3421053	GO:0070663	GO:BP	regulation of leukocyte proliferation	16175	16244	GO:00421….
query_1	TRUE	0.0000000	169	887	61	0.0687711	0.3609467	GO:0050670	GO:BP	regulation of lymphocyte proliferation	16175	13204	GO:00329….
query_1	TRUE	0.0000000	171	887	61	0.0687711	0.3567251	GO:0032944	GO:BP	regulation of mononuclear cell proliferation	16175	7929	GO:00329….
query_1	TRUE	0.0000000	257	887	74	0.0834273	0.2879377	GO:0022409	GO:BP	positive regulation of cell-cell adhesion	16175	6600	GO:00224….
query_1	TRUE	0.0000000	215	887	67	0.0755355	0.3116279	GO:1903039	GO:BP	positive regulation of leukocyte cell-cell adhesion	16175	22719	GO:00071….
query_1	TRUE	0.0000000	297	887	78	0.0879369	0.2626263	GO:0030098	GO:BP	lymphocyte differentiation	16175	6676	GO:00466….
query_1	TRUE	0.0000000	5277	887	455	0.5129651	0.0862232	GO:0032501	GO:BP	multicellular organismal process	16175	7611	GO:0008150
query_1	TRUE	0.0000000	625	887	116	0.1307779	0.1856000	GO:0034097	GO:BP	response to cytokine	16175	8408	GO:1901652
query_1	TRUE	0.0000000	625	887	116	0.1307779	0.1856000	GO:1901652	GO:BP	response to peptide	16175	21619	GO:0042221
query_1	TRUE	0.0000000	216	887	65	0.0732807	0.3009259	GO:0002366	GO:BP	leukocyte activation involved in immune response	16175	898	GO:00022….
query_1	TRUE	0.0000000	555	887	106	0.1195039	0.1909910	GO:0071345	GO:BP	cellular response to cytokine stimulus	16175	16597	GO:0034097
query_1	TRUE	0.0000000	531	887	103	0.1161218	0.1939736	GO:0032103	GO:BP	positive regulation of response to external stimulus	16175	7367	GO:00096….
query_1	TRUE	0.0000000	221	887	65	0.0732807	0.2941176	GO:0002263	GO:BP	cell activation involved in immune response	16175	795	GO:00017….
query_1	TRUE	0.0000000	195	887	61	0.0687711	0.3128205	GO:0050870	GO:BP	positive regulation of T cell activation	16175	13318	GO:00421….
query_1	TRUE	0.0000000	304	887	76	0.0856821	0.2500000	GO:0050900	GO:BP	leukocyte migration	16175	13342	GO:00023….
query_1	TRUE	0.0000000	622	887	112	0.1262683	0.1800643	GO:0030155	GO:BP	regulation of cell adhesion	16175	6688	GO:00071….
query_1	TRUE	0.0000000	5229	887	445	0.5016911	0.0851023	GO:0048518	GO:BP	positive regulation of biological process	16175	12801	GO:00081….
query_1	TRUE	0.0000000	147	887	52	0.0586246	0.3537415	GO:0019724	GO:BP	B cell mediated immunity	16175	6019	GO:00024….
query_1	TRUE	0.0000000	5898	887	479	0.5400225	0.0812140	GO:0051716	GO:BP	cellular response to stimulus	16175	13909	GO:00099….
query_1	TRUE	0.0000000	451	887	90	0.1014656	0.1995565	GO:0002831	GO:BP	regulation of response to biotic stimulus	16175	1341	GO:00096….
query_1	TRUE	0.0000000	419	887	86	0.0969560	0.2052506	GO:0019221	GO:BP	cytokine-mediated signaling pathway	16175	5598	GO:00071….
query_1	TRUE	0.0000000	206	887	59	0.0665163	0.2864078	GO:0030217	GO:BP	T cell differentiation	16175	6725	GO:00300….
query_1	TRUE	0.0000000	373	887	80	0.0901917	0.2144772	GO:0045785	GO:BP	positive regulation of cell adhesion	16175	11617	GO:00071….
query_1	TRUE	0.0000000	142	887	49	0.0552424	0.3450704	GO:0016064	GO:BP	immunoglobulin mediated immune response	16175	5095	GO:0019724
query_1	TRUE	0.0000000	125	887	45	0.0507328	0.3600000	GO:0046631	GO:BP	alpha-beta T cell activation	16175	12268	GO:0042110
query_1	TRUE	0.0000000	55	887	31	0.0349493	0.5636364	GO:0050853	GO:BP	B cell receptor signaling pathway	16175	13301	GO:0050851
query_1	TRUE	0.0000000	228	887	60	0.0676437	0.2631579	GO:1902105	GO:BP	regulation of leukocyte differentiation	16175	22019	GO:00025….
query_1	TRUE	0.0000000	386	887	79	0.0890643	0.2046632	GO:0045088	GO:BP	regulation of innate immune response	16175	11271	GO:00028….
query_1	TRUE	0.0000000	795	887	120	0.1352875	0.1509434	GO:0051241	GO:BP	negative regulation of multicellular organismal process	16175	13591	GO:00325….
query_1	TRUE	0.0000000	423	887	83	0.0935738	0.1962175	GO:0031349	GO:BP	positive regulation of defense response	16175	7140	GO:00069….
query_1	TRUE	0.0000000	197	887	55	0.0620068	0.2791878	GO:0042113	GO:BP	B cell activation	16175	9971	GO:0046649
query_1	TRUE	0.0000000	119	887	43	0.0484780	0.3613445	GO:0070665	GO:BP	positive regulation of leukocyte proliferation	16175	16246	GO:00082….
query_1	TRUE	0.0000000	104	887	40	0.0450958	0.3846154	GO:0050671	GO:BP	positive regulation of lymphocyte proliferation	16175	13205	GO:00329….
query_1	TRUE	0.0000000	167	887	50	0.0563698	0.2994012	GO:0002274	GO:BP	myeloid leukocyte activation	16175	806	GO:0045321
query_1	TRUE	0.0000000	105	887	40	0.0450958	0.3809524	GO:0032946	GO:BP	positive regulation of mononuclear cell proliferation	16175	7931	GO:00329….
query_1	TRUE	0.0000000	146	887	46	0.0518602	0.3150685	GO:0050866	GO:BP	negative regulation of cell activation	16175	13314	GO:00017….
query_1	TRUE	0.0000000	1546	887	179	0.2018038	0.1157827	GO:0141124	GO:BP	intracellular signaling cassette	16175	20031	GO:0035556
query_1	TRUE	0.0000000	140	887	45	0.0507328	0.3214286	GO:0042098	GO:BP	T cell proliferation	16175	9965	GO:00421….
query_1	TRUE	0.0000000	168	887	49	0.0552424	0.2916667	GO:0001906	GO:BP	cell killing	16175	524	GO:0009987
query_1	TRUE	0.0000000	188	887	51	0.0574972	0.2712766	GO:0071674	GO:BP	mononuclear cell migration	16175	16847	GO:0050900
query_1	TRUE	0.0000000	127	887	42	0.0473506	0.3307087	GO:0002695	GO:BP	negative regulation of leukocyte activation	16175	1213	GO:00026….
query_1	TRUE	0.0000000	98	887	37	0.0417136	0.3775510	GO:0019882	GO:BP	antigen processing and presentation	16175	6060	GO:0002376
query_1	TRUE	0.0000000	177	887	49	0.0552424	0.2768362	GO:0002703	GO:BP	regulation of leukocyte mediated immunity	16175	1221	GO:00024….
query_1	TRUE	0.0000000	339	887	69	0.0777903	0.2035398	GO:0002833	GO:BP	positive regulation of response to biotic stimulus	16175	1343	GO:00028….
query_1	TRUE	0.0000000	273	887	61	0.0687711	0.2234432	GO:0060326	GO:BP	cell chemotaxis	16175	14538	GO:00069….
query_1	TRUE	0.0000000	319	887	66	0.0744081	0.2068966	GO:0045089	GO:BP	positive regulation of innate immune response	16175	11272	GO:00028….
query_1	TRUE	0.0000000	114	887	39	0.0439684	0.3421053	GO:0050852	GO:BP	T cell receptor signaling pathway	16175	13300	GO:0050851
query_1	TRUE	0.0000000	1150	887	143	0.1612176	0.1243478	GO:0080134	GO:BP	regulation of response to stress	16175	17816	GO:00069….
query_1	TRUE	0.0000000	1392	887	162	0.1826381	0.1163793	GO:0008283	GO:BP	cell population proliferation	16175	3150	GO:0009987
query_1	TRUE	0.0000000	443	887	79	0.0890643	0.1783296	GO:0009617	GO:BP	response to bacterium	16175	3543	GO:0051707
query_1	TRUE	0.0000000	192	887	50	0.0563698	0.2604167	GO:0002699	GO:BP	positive regulation of immune effector process	16175	1217	GO:00022….
query_1	TRUE	0.0000000	200	887	51	0.0574972	0.2550000	GO:0030595	GO:BP	leukocyte chemotaxis	16175	6861	GO:00509….
query_1	TRUE	0.0000000	1221	887	148	0.1668546	0.1212121	GO:0042127	GO:BP	regulation of cell population proliferation	16175	9981	GO:00082….
query_1	TRUE	0.0000000	299	887	63	0.0710259	0.2107023	GO:0050727	GO:BP	regulation of inflammatory response	16175	13226	GO:00069….
query_1	TRUE	0.0000000	309	887	64	0.0721533	0.2071197	GO:1903706	GO:BP	regulation of hemopoiesis	16175	23220	GO:00026….
query_1	TRUE	0.0000000	106	887	37	0.0417136	0.3490566	GO:0001909	GO:BP	leukocyte mediated cytotoxicity	16175	526	GO:00019….
query_1	TRUE	0.0000000	152	887	44	0.0496054	0.2894737	GO:0071219	GO:BP	cellular response to molecule of bacterial origin	16175	16481	GO:00022….
query_1	TRUE	0.0000000	375	887	71	0.0800451	0.1893333	GO:0006935	GO:BP	chemotaxis	16175	2574	GO:00422….
query_1	TRUE	0.0000000	375	887	71	0.0800451	0.1893333	GO:0042330	GO:BP	taxis	16175	10096	GO:00096….
query_1	TRUE	0.0000000	945	887	124	0.1397971	0.1312169	GO:0010628	GO:BP	positive regulation of gene expression	16175	4274	GO:00104….
query_1	TRUE	0.0000000	128	887	40	0.0450958	0.3125000	GO:0042129	GO:BP	regulation of T cell proliferation	16175	9983	GO:00420….
query_1	TRUE	0.0000000	4915	887	394	0.4441939	0.0801628	GO:0048522	GO:BP	positive regulation of cellular process	16175	12805	GO:00099….
query_1	TRUE	0.0000000	172	887	45	0.0507328	0.2616279	GO:0071216	GO:BP	cellular response to biotic stimulus	16175	16478	GO:00096….
query_1	TRUE	0.0000000	158	887	43	0.0484780	0.2721519	GO:0002285	GO:BP	lymphocyte activation involved in immune response	16175	817	GO:00023….
query_1	TRUE	0.0000000	1018	887	127	0.1431793	0.1247544	GO:2000026	GO:BP	regulation of multicellular organismal development	16175	25389	GO:00072….
query_1	TRUE	0.0000000	686	887	98	0.1104848	0.1428571	GO:0008284	GO:BP	positive regulation of cell population proliferation	16175	3151	GO:00082….
query_1	TRUE	0.0000000	106	887	35	0.0394589	0.3301887	GO:0051250	GO:BP	negative regulation of lymphocyte activation	16175	13597	GO:00026….
query_1	TRUE	0.0000000	154	887	42	0.0473506	0.2727273	GO:0002819	GO:BP	regulation of adaptive immune response	16175	1329	GO:00022….
query_1	TRUE	0.0000000	10121	887	674	0.7598647	0.0665942	GO:0050789	GO:BP	regulation of biological process	16175	13258	GO:00081….
query_1	TRUE	0.0000000	77	887	30	0.0338219	0.3896104	GO:0042102	GO:BP	positive regulation of T cell proliferation	16175	9967	GO:00420….
query_1	TRUE	0.0000000	203	887	48	0.0541150	0.2364532	GO:0002237	GO:BP	response to molecule of bacterial origin	16175	770	GO:00096….
query_1	TRUE	0.0000000	91	887	32	0.0360767	0.3516484	GO:0031341	GO:BP	regulation of cell killing	16175	7132	GO:00019….
query_1	TRUE	0.0000000	91	887	32	0.0360767	0.3516484	GO:0050864	GO:BP	regulation of B cell activation	16175	13312	GO:00421….
query_1	TRUE	0.0000000	92	887	32	0.0360767	0.3478261	GO:0032612	GO:BP	interleukin-1 production	16175	7660	GO:0001816
query_1	TRUE	0.0000000	92	887	32	0.0360767	0.3478261	GO:0032652	GO:BP	regulation of interleukin-1 production	16175	7699	GO:00018….
query_1	TRUE	0.0000000	81	887	30	0.0338219	0.3703704	GO:0032611	GO:BP	interleukin-1 beta production	16175	7659	GO:0032612
query_1	TRUE	0.0000000	81	887	30	0.0338219	0.3703704	GO:0032651	GO:BP	regulation of interleukin-1 beta production	16175	7698	GO:00326….
query_1	TRUE	0.0000000	50	887	24	0.0270575	0.4800000	GO:0050854	GO:BP	regulation of antigen receptor-mediated signaling pathway	16175	13302	GO:00099….
query_1	TRUE	0.0000000	50	887	24	0.0270575	0.4800000	GO:0006968	GO:BP	cellular defense response	16175	2596	GO:0006952
query_1	TRUE	0.0000000	2450	887	229	0.2581736	0.0934694	GO:0035556	GO:BP	intracellular signal transduction	16175	9090	GO:0007165
query_1	TRUE	0.0000000	571	887	85	0.0958286	0.1488616	GO:0060284	GO:BP	regulation of cell development	16175	14500	GO:00455….
query_1	TRUE	0.0000000	90	887	31	0.0349493	0.3444444	GO:0032609	GO:BP	type II interferon production	16175	7657	GO:0001816
query_1	TRUE	0.0000000	90	887	31	0.0349493	0.3444444	GO:0032649	GO:BP	regulation of type II interferon production	16175	7696	GO:00018….
query_1	TRUE	0.0000000	1297	887	145	0.1634724	0.1117965	GO:0009967	GO:BP	positive regulation of signal transduction	16175	3805	GO:00071….
query_1	TRUE	0.0000000	116	887	35	0.0394589	0.3017241	GO:0032635	GO:BP	interleukin-6 production	16175	7682	GO:0001816
query_1	TRUE	0.0000000	116	887	35	0.0394589	0.3017241	GO:0032675	GO:BP	regulation of interleukin-6 production	16175	7721	GO:00018….
query_1	TRUE	0.0000000	152	887	40	0.0450958	0.2631579	GO:0045619	GO:BP	regulation of lymphocyte differentiation	16175	11470	GO:00300….
query_1	TRUE	0.0000000	9721	887	649	0.7316798	0.0667627	GO:0050794	GO:BP	regulation of cellular process	16175	13262	GO:00099….
query_1	TRUE	0.0000000	224	887	49	0.0552424	0.2187500	GO:0006959	GO:BP	humoral immune response	16175	2590	GO:0006955
query_1	TRUE	0.0000000	185	887	44	0.0496054	0.2378378	GO:0006909	GO:BP	phagocytosis	16175	2559	GO:0006897
query_1	TRUE	0.0000000	10482	887	686	0.7733935	0.0654455	GO:0065007	GO:BP	biological regulation	16175	15890	GO:0008150
query_1	TRUE	0.0000000	186	887	44	0.0496054	0.2365591	GO:0097529	GO:BP	myeloid leukocyte migration	16175	18689	GO:0050900
query_1	TRUE	0.0000000	228	887	49	0.0552424	0.2149123	GO:0001818	GO:BP	negative regulation of cytokine production	16175	475	GO:00018….
query_1	TRUE	0.0000000	263	887	53	0.0597520	0.2015209	GO:0002218	GO:BP	activation of innate immune response	16175	753	GO:00022….
query_1	TRUE	0.0000000	936	887	115	0.1296505	0.1228632	GO:1902533	GO:BP	positive regulation of intracellular signal transduction	16175	22342	GO:00099….
query_1	TRUE	0.0000000	142	887	38	0.0428410	0.2676056	GO:0071222	GO:BP	cellular response to lipopolysaccharide	16175	16484	GO:00324….
query_1	TRUE	0.0000000	1205	887	136	0.1533258	0.1128631	GO:0016477	GO:BP	cell migration	16175	5229	GO:0048870
query_1	TRUE	0.0000000	1876	887	185	0.2085682	0.0986141	GO:0048468	GO:BP	cell development	16175	12769	GO:00301….
query_1	TRUE	0.0000000	78	887	28	0.0315671	0.3589744	GO:0001910	GO:BP	regulation of leukocyte mediated cytotoxicity	16175	527	GO:00019….
query_1	TRUE	0.0000000	2551	887	231	0.2604284	0.0905527	GO:0042221	GO:BP	response to chemical	16175	10049	GO:0050896
query_1	TRUE	0.0000000	1424	887	151	0.1702368	0.1060393	GO:0010647	GO:BP	positive regulation of cell communication	16175	4293	GO:00071….
query_1	TRUE	0.0000000	149	887	38	0.0428410	0.2550336	GO:0050777	GO:BP	negative regulation of immune response	16175	13251	GO:00026….
query_1	TRUE	0.0000000	165	887	40	0.0450958	0.2424242	GO:0002573	GO:BP	myeloid leukocyte differentiation	16175	1094	GO:00025….
query_1	TRUE	0.0000000	1427	887	151	0.1702368	0.1058164	GO:0023056	GO:BP	positive regulation of signaling	16175	6641	GO:00230….
query_1	TRUE	0.0000000	107	887	32	0.0360767	0.2990654	GO:0034341	GO:BP	response to type II interferon	16175	8579	GO:00340….
query_1	TRUE	0.0000000	243	887	49	0.0552424	0.2016461	GO:0002758	GO:BP	innate immune response-activating signaling pathway	16175	1269	GO:00022….
query_1	TRUE	0.0000000	76	887	27	0.0304397	0.3552632	GO:0042100	GO:BP	B cell proliferation	16175	9966	GO:00421….
query_1	TRUE	0.0000000	102	887	31	0.0349493	0.3039216	GO:0072676	GO:BP	lymphocyte migration	16175	17494	GO:0071674
query_1	TRUE	0.0000000	1647	887	166	0.1871477	0.1007893	GO:1902531	GO:BP	regulation of intracellular signal transduction	16175	22340	GO:00099….
query_1	TRUE	0.0000000	139	887	36	0.0405862	0.2589928	GO:0002822	GO:BP	regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	16175	1332	GO:00024….
query_1	TRUE	0.0000000	84	887	28	0.0315671	0.3333333	GO:0046634	GO:BP	regulation of alpha-beta T cell activation	16175	12271	GO:00466….
query_1	TRUE	0.0000000	187	887	42	0.0473506	0.2245989	GO:0032496	GO:BP	response to lipopolysaccharide	16175	7607	GO:00022….
query_1	TRUE	0.0000000	133	887	35	0.0394589	0.2631579	GO:1903555	GO:BP	regulation of tumor necrosis factor superfamily cytokine production	16175	23102	GO:00018….
query_1	TRUE	0.0000000	133	887	35	0.0394589	0.2631579	GO:0071706	GO:BP	tumor necrosis factor superfamily cytokine production	16175	16870	GO:0001816
query_1	TRUE	0.0000000	85	887	28	0.0315671	0.3294118	GO:0046632	GO:BP	alpha-beta T cell differentiation	16175	12269	GO:00302….
query_1	TRUE	0.0000000	85	887	28	0.0315671	0.3294118	GO:0071346	GO:BP	cellular response to type II interferon	16175	16598	GO:00343….
query_1	TRUE	0.0000000	56	887	23	0.0259301	0.4107143	GO:0043299	GO:BP	leukocyte degranulation	16175	10607	GO:00022….
query_1	TRUE	0.0000000	56	887	23	0.0259301	0.4107143	GO:0032731	GO:BP	positive regulation of interleukin-1 beta production	16175	7776	GO:00326….
query_1	TRUE	0.0000000	150	887	37	0.0417136	0.2466667	GO:0002440	GO:BP	production of molecular mediator of immune response	16175	963	GO:00023….
query_1	TRUE	0.0000000	62	887	24	0.0270575	0.3870968	GO:0048002	GO:BP	antigen processing and presentation of peptide antigen	16175	12460	GO:0019882
query_1	TRUE	0.0000000	80	887	27	0.0304397	0.3375000	GO:0002698	GO:BP	negative regulation of immune effector process	16175	1216	GO:00022….
query_1	TRUE	0.0000000	136	887	35	0.0394589	0.2573529	GO:0002706	GO:BP	regulation of lymphocyte mediated immunity	16175	1224	GO:00024….
query_1	TRUE	0.0000000	63	887	24	0.0270575	0.3809524	GO:0032732	GO:BP	positive regulation of interleukin-1 production	16175	7777	GO:00018….
query_1	TRUE	0.0000000	47	887	21	0.0236753	0.4468085	GO:0030888	GO:BP	regulation of B cell proliferation	16175	6953	GO:00421….
query_1	TRUE	0.0000000	530	887	76	0.0856821	0.1433962	GO:0043408	GO:BP	regulation of MAPK cascade	16175	10676	GO:00001….
query_1	TRUE	0.0000000	123	887	33	0.0372041	0.2682927	GO:0002700	GO:BP	regulation of production of molecular mediator of immune response	16175	1218	GO:00024….
query_1	TRUE	0.0000000	110	887	31	0.0349493	0.2818182	GO:0071621	GO:BP	granulocyte chemotaxis	16175	16801	GO:00305….
query_1	TRUE	0.0000000	60	887	23	0.0259301	0.3833333	GO:0032729	GO:BP	positive regulation of type II interferon production	16175	7774	GO:00018….
query_1	TRUE	0.0000000	91	887	28	0.0315671	0.3076923	GO:0030593	GO:BP	neutrophil chemotaxis	16175	6860	GO:00716….
query_1	TRUE	0.0000000	127	887	33	0.0372041	0.2598425	GO:0097530	GO:BP	granulocyte migration	16175	18690	GO:0097529
query_1	TRUE	0.0000000	227	887	45	0.0507328	0.1982379	GO:0002221	GO:BP	pattern recognition receptor signaling pathway	16175	755	GO:0002758
query_1	TRUE	0.0000000	128	887	33	0.0372041	0.2578125	GO:0032640	GO:BP	tumor necrosis factor production	16175	7687	GO:0071706
query_1	TRUE	0.0000000	128	887	33	0.0372041	0.2578125	GO:0032680	GO:BP	regulation of tumor necrosis factor production	16175	7726	GO:00326….
query_1	TRUE	0.0000000	40	887	19	0.0214205	0.4750000	GO:0031295	GO:BP	T cell costimulation	16175	7117	GO:00312….
query_1	TRUE	0.0000000	129	887	33	0.0372041	0.2558140	GO:0045580	GO:BP	regulation of T cell differentiation	16175	11431	GO:00302….
query_1	TRUE	0.0000000	100	887	29	0.0326945	0.2900000	GO:0002286	GO:BP	T cell activation involved in immune response	16175	818	GO:00022….
query_1	TRUE	0.0000000	100	887	29	0.0326945	0.2900000	GO:1903038	GO:BP	negative regulation of leukocyte cell-cell adhesion	16175	22718	GO:00071….
query_1	TRUE	0.0000000	376	887	60	0.0676437	0.1595745	GO:0043410	GO:BP	positive regulation of MAPK cascade	16175	10678	GO:00001….
query_1	TRUE	0.0000000	2543	887	223	0.2514092	0.0876917	GO:0009966	GO:BP	regulation of signal transduction	16175	3804	GO:00071….
query_1	TRUE	0.0000000	595	887	80	0.0901917	0.1344538	GO:0000165	GO:BP	MAPK cascade	16175	55	GO:0141124
query_1	TRUE	0.0000000	63	887	23	0.0259301	0.3650794	GO:0002275	GO:BP	myeloid cell activation involved in immune response	16175	807	GO:00022….
query_1	TRUE	0.0000000	319	887	54	0.0608794	0.1692790	GO:0032102	GO:BP	negative regulation of response to external stimulus	16175	7366	GO:00096….
query_1	TRUE	0.0000000	172	887	38	0.0428410	0.2209302	GO:0002685	GO:BP	regulation of leukocyte migration	16175	1203	GO:00026….
query_1	TRUE	0.0000000	1005	887	113	0.1273957	0.1124378	GO:0040011	GO:BP	locomotion	16175	9899	GO:0008150
query_1	TRUE	0.0000000	89	887	27	0.0304397	0.3033708	GO:0050868	GO:BP	negative regulation of T cell activation	16175	13316	GO:00421….
query_1	TRUE	0.0000000	42	887	19	0.0214205	0.4523810	GO:0031294	GO:BP	lymphocyte costimulation	16175	7116	GO:00023….
query_1	TRUE	0.0000000	334	887	55	0.0620068	0.1646707	GO:0009615	GO:BP	response to virus	16175	3541	GO:0051707
query_1	TRUE	0.0000000	98	887	28	0.0315671	0.2857143	GO:0002456	GO:BP	T cell mediated immunity	16175	979	GO:00024….
query_1	TRUE	0.0000000	25	887	15	0.0169109	0.6000000	GO:0036336	GO:BP	dendritic cell migration	16175	9571	GO:0071674
query_1	TRUE	0.0000000	106	887	29	0.0326945	0.2735849	GO:1990266	GO:BP	neutrophil migration	16175	25128	GO:0097530
query_1	TRUE	0.0000000	39	887	18	0.0202931	0.4615385	GO:0019884	GO:BP	antigen processing and presentation of exogenous antigen	16175	6062	GO:0019882
query_1	TRUE	0.0000000	1373	887	139	0.1567080	0.1012382	GO:0048870	GO:BP	cell motility	16175	13113	GO:0009987
query_1	TRUE	0.0000000	124	887	31	0.0349493	0.2500000	GO:0050729	GO:BP	positive regulation of inflammatory response	16175	13228	GO:00069….
query_1	TRUE	0.0000000	148	887	34	0.0383315	0.2297297	GO:0022408	GO:BP	negative regulation of cell-cell adhesion	16175	6599	GO:00071….
query_1	TRUE	0.0000000	88	887	26	0.0293123	0.2954545	GO:0035710	GO:BP	CD4-positive, alpha-beta T cell activation	16175	9184	GO:0046631
query_1	TRUE	0.0000000	63	887	22	0.0248027	0.3492063	GO:0031343	GO:BP	positive regulation of cell killing	16175	7134	GO:00019….
query_1	TRUE	0.0000000	46	887	19	0.0214205	0.4130435	GO:0002704	GO:BP	negative regulation of leukocyte mediated immunity	16175	1222	GO:00024….
query_1	TRUE	0.0000000	48	887	19	0.0214205	0.3958333	GO:0032623	GO:BP	interleukin-2 production	16175	7670	GO:0001816
query_1	TRUE	0.0000000	48	887	19	0.0214205	0.3958333	GO:0032663	GO:BP	regulation of interleukin-2 production	16175	7709	GO:00018….
query_1	TRUE	0.0000000	29	887	15	0.0169109	0.5172414	GO:0002495	GO:BP	antigen processing and presentation of peptide antigen via MHC class II	16175	1018	GO:00025….
query_1	TRUE	0.0000000	29	887	15	0.0169109	0.5172414	GO:0097028	GO:BP	dendritic cell differentiation	16175	18451	GO:1903131
query_1	TRUE	0.0000000	81	887	24	0.0270575	0.2962963	GO:0050764	GO:BP	regulation of phagocytosis	16175	13238	GO:00069….
query_1	TRUE	0.0000000	110	887	28	0.0315671	0.2545455	GO:0002705	GO:BP	positive regulation of leukocyte mediated immunity	16175	1223	GO:00024….
query_1	TRUE	0.0000000	68	887	22	0.0248027	0.3235294	GO:0070098	GO:BP	chemokine-mediated signaling pathway	16175	15910	GO:00071….
query_1	TRUE	0.0000000	50	887	19	0.0214205	0.3800000	GO:0032655	GO:BP	regulation of interleukin-12 production	16175	7702	GO:00018….
query_1	TRUE	0.0000000	50	887	19	0.0214205	0.3800000	GO:0032615	GO:BP	interleukin-12 production	16175	7663	GO:0001816
query_1	TRUE	0.0000000	1790	887	165	0.1860203	0.0921788	GO:0050793	GO:BP	regulation of developmental process	16175	13261	GO:00325….
query_1	TRUE	0.0000000	291	887	48	0.0541150	0.1649485	GO:0030099	GO:BP	myeloid cell differentiation	16175	6677	GO:00300….
query_1	TRUE	0.0000000	82	887	24	0.0270575	0.2926829	GO:0032677	GO:BP	regulation of interleukin-8 production	16175	7723	GO:00018….
query_1	TRUE	0.0000000	82	887	24	0.0270575	0.2926829	GO:0032637	GO:BP	interleukin-8 production	16175	7684	GO:0001816
query_1	TRUE	0.0000000	2816	887	233	0.2626832	0.0827415	GO:0010646	GO:BP	regulation of cell communication	16175	4292	GO:00071….
query_1	TRUE	0.0000000	76	887	23	0.0259301	0.3026316	GO:1990869	GO:BP	cellular response to chemokine	16175	25324	GO:00713….
query_1	TRUE	0.0000000	76	887	23	0.0259301	0.3026316	GO:1990868	GO:BP	response to chemokine	16175	25323	GO:0034097
query_1	TRUE	0.0000000	63	887	21	0.0236753	0.3333333	GO:0070664	GO:BP	negative regulation of leukocyte proliferation	16175	16245	GO:00082….
query_1	TRUE	0.0000000	197	887	38	0.0428410	0.1928934	GO:0031348	GO:BP	negative regulation of defense response	16175	7139	GO:00069….
query_1	TRUE	0.0000000	2808	887	232	0.2615558	0.0826211	GO:0023051	GO:BP	regulation of signaling	16175	6639	GO:00230….
query_1	TRUE	0.0000000	1404	887	137	0.1544532	0.0975783	GO:0012501	GO:BP	programmed cell death	16175	4572	GO:0008219
query_1	TRUE	0.0000000	22	887	13	0.0146561	0.5909091	GO:0002407	GO:BP	dendritic cell chemotaxis	16175	931	GO:00305….
query_1	TRUE	0.0000000	114	887	28	0.0315671	0.2456140	GO:0071675	GO:BP	regulation of mononuclear cell migration	16175	16848	GO:00026….
query_1	TRUE	0.0000000	1409	887	137	0.1544532	0.0972321	GO:0008219	GO:BP	cell death	16175	3146	GO:0009987
query_1	TRUE	0.0000000	31	887	15	0.0169109	0.4838710	GO:0002504	GO:BP	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	16175	1027	GO:0019882
query_1	TRUE	0.0000000	78	887	23	0.0259301	0.2948718	GO:0032755	GO:BP	positive regulation of interleukin-6 production	16175	7799	GO:00018….
query_1	TRUE	0.0000000	1123	887	116	0.1307779	0.1032947	GO:0045595	GO:BP	regulation of cell differentiation	16175	11446	GO:00301….
query_1	TRUE	0.0000000	72	887	22	0.0248027	0.3055556	GO:0043367	GO:BP	CD4-positive, alpha-beta T cell differentiation	16175	10644	GO:00357….
query_1	TRUE	0.0000000	72	887	22	0.0248027	0.3055556	GO:0002444	GO:BP	myeloid leukocyte mediated immunity	16175	967	GO:0002443
query_1	TRUE	0.0000000	166	887	34	0.0383315	0.2048193	GO:0019722	GO:BP	calcium-mediated signaling	16175	6018	GO:0141124
query_1	TRUE	0.0000000	79	887	23	0.0259301	0.2911392	GO:0002367	GO:BP	cytokine production involved in immune response	16175	899	GO:00018….
query_1	TRUE	0.0000000	79	887	23	0.0259301	0.2911392	GO:0002718	GO:BP	regulation of cytokine production involved in immune response	16175	1236	GO:00018….
query_1	TRUE	0.0000000	66	887	21	0.0236753	0.3181818	GO:0002292	GO:BP	T cell differentiation involved in immune response	16175	824	GO:00022….
query_1	TRUE	0.0000000	117	887	28	0.0315671	0.2393162	GO:0002687	GO:BP	positive regulation of leukocyte migration	16175	1205	GO:00026….
query_1	TRUE	0.0000000	37	887	16	0.0180383	0.4324324	GO:0045058	GO:BP	T cell selection	16175	11256	GO:00023….
query_1	TRUE	0.0000000	60	887	20	0.0225479	0.3333333	GO:0002228	GO:BP	natural killer cell mediated immunity	16175	761	GO:00024….
query_1	TRUE	0.0000000	80	887	23	0.0259301	0.2875000	GO:0002709	GO:BP	regulation of T cell mediated immunity	16175	1227	GO:00024….
query_1	TRUE	0.0000000	67	887	21	0.0236753	0.3134328	GO:0002548	GO:BP	monocyte chemotaxis	16175	1069	GO:00305….
query_1	TRUE	0.0000000	1347	887	131	0.1476888	0.0972532	GO:0006915	GO:BP	apoptotic process	16175	2564	GO:0012501
query_1	TRUE	0.0000000	33	887	15	0.0169109	0.4545455	GO:0045730	GO:BP	respiratory burst	16175	11572	GO:0008152
query_1	TRUE	0.0000000	33	887	15	0.0169109	0.4545455	GO:0002478	GO:BP	antigen processing and presentation of exogenous peptide antigen	16175	1001	GO:00198….
query_1	TRUE	0.0000000	62	887	20	0.0225479	0.3225806	GO:0002293	GO:BP	alpha-beta T cell differentiation involved in immune response	16175	825	GO:00022….
query_1	TRUE	0.0000000	62	887	20	0.0225479	0.3225806	GO:0002287	GO:BP	alpha-beta T cell activation involved in immune response	16175	819	GO:00022….
query_1	TRUE	0.0000000	105	887	26	0.0293123	0.2476190	GO:0070555	GO:BP	response to interleukin-1	16175	16175	GO:0034097
query_1	TRUE	0.0000000	56	887	19	0.0214205	0.3392857	GO:0006956	GO:BP	complement activation	16175	2587	GO:00022….
query_1	TRUE	0.0000000	139	887	30	0.0338219	0.2158273	GO:1903708	GO:BP	positive regulation of hemopoiesis	16175	23222	GO:00026….
query_1	TRUE	0.0000000	139	887	30	0.0338219	0.2158273	GO:1902107	GO:BP	positive regulation of leukocyte differentiation	16175	22021	GO:00025….
query_1	TRUE	0.0000000	84	887	23	0.0259301	0.2738095	GO:1903557	GO:BP	positive regulation of tumor necrosis factor superfamily cytokine production	16175	23104	GO:00018….
query_1	TRUE	0.0000000	57	887	19	0.0214205	0.3333333	GO:0050672	GO:BP	negative regulation of lymphocyte proliferation	16175	13206	GO:00329….
query_1	TRUE	0.0000000	57	887	19	0.0214205	0.3333333	GO:0072678	GO:BP	T cell migration	16175	17496	GO:0072676
query_1	TRUE	0.0000000	57	887	19	0.0214205	0.3333333	GO:0001912	GO:BP	positive regulation of leukocyte mediated cytotoxicity	16175	529	GO:00019….
query_1	TRUE	0.0000000	774	887	87	0.0980834	0.1124031	GO:0007186	GO:BP	G protein-coupled receptor signaling pathway	16175	2744	GO:0007165
query_1	TRUE	0.0000000	58	887	19	0.0214205	0.3275862	GO:0032945	GO:BP	negative regulation of mononuclear cell proliferation	16175	7930	GO:00329….
query_1	TRUE	0.0000000	17	887	11	0.0124014	0.6470588	GO:0050855	GO:BP	regulation of B cell receptor signaling pathway	16175	13303	GO:00508….
query_1	TRUE	0.0000000	30	887	14	0.0157835	0.4666667	GO:0042088	GO:BP	T-helper 1 type immune response	16175	9962	GO:0002460
query_1	TRUE	0.0000000	533	887	67	0.0755355	0.1257036	GO:0006897	GO:BP	endocytosis	16175	2551	GO:00161….
query_1	TRUE	0.0000000	59	887	19	0.0214205	0.3220339	GO:0042267	GO:BP	natural killer cell mediated cytotoxicity	16175	10065	GO:00019….
query_1	TRUE	0.0000000	59	887	19	0.0214205	0.3220339	GO:0048247	GO:BP	lymphocyte chemotaxis	16175	12605	GO:00305….
query_1	TRUE	0.0000000	59	887	19	0.0214205	0.3220339	GO:0002224	GO:BP	toll-like receptor signaling pathway	16175	758	GO:0002221
query_1	TRUE	0.0000000	80	887	22	0.0248027	0.2750000	GO:0032760	GO:BP	positive regulation of tumor necrosis factor production	16175	7804	GO:00326….
query_1	TRUE	0.0000000	228	887	39	0.0439684	0.1710526	GO:0051607	GO:BP	defense response to virus	16175	13823	GO:00096….
query_1	TRUE	0.0000000	104	887	25	0.0281849	0.2403846	GO:0002688	GO:BP	regulation of leukocyte chemotaxis	16175	1206	GO:00026….
query_1	TRUE	0.0000000	54	887	18	0.0202931	0.3333333	GO:0046637	GO:BP	regulation of alpha-beta T cell differentiation	16175	12274	GO:00455….
query_1	TRUE	0.0000000	18	887	11	0.0124014	0.6111111	GO:0002577	GO:BP	regulation of antigen processing and presentation	16175	1098	GO:00026….
query_1	TRUE	0.0000000	61	887	19	0.0214205	0.3114754	GO:0002294	GO:BP	CD4-positive, alpha-beta T cell differentiation involved in immune response	16175	826	GO:00022….
query_1	TRUE	0.0000000	75	887	21	0.0236753	0.2800000	GO:1902106	GO:BP	negative regulation of leukocyte differentiation	16175	22020	GO:00025….
query_1	TRUE	0.0000000	232	887	39	0.0439684	0.1681034	GO:0007162	GO:BP	negative regulation of cell adhesion	16175	2726	GO:00071….
query_1	TRUE	0.0000000	4231	887	313	0.3528749	0.0739778	GO:0048856	GO:BP	anatomical structure development	16175	13100	GO:0032502
query_1	TRUE	0.0000000	214	887	37	0.0417136	0.1728972	GO:0018108	GO:BP	peptidyl-tyrosine phosphorylation	16175	5327	GO:00064….
query_1	TRUE	0.0000000	244	887	40	0.0450958	0.1639344	GO:0042742	GO:BP	defense response to bacterium	16175	10335	GO:00096….
query_1	TRUE	0.0000000	255	887	41	0.0462232	0.1607843	GO:0070371	GO:BP	ERK1 and ERK2 cascade	16175	16082	GO:0000165
query_1	TRUE	0.0000000	215	887	37	0.0417136	0.1720930	GO:0018212	GO:BP	peptidyl-tyrosine modification	16175	5371	GO:0018193
query_1	TRUE	0.0000000	77	887	21	0.0236753	0.2727273	GO:1903707	GO:BP	negative regulation of hemopoiesis	16175	23221	GO:00026….
query_1	TRUE	0.0000000	116	887	26	0.0293123	0.2241379	GO:0050921	GO:BP	positive regulation of chemotaxis	16175	13363	GO:00069….
query_1	TRUE	0.0000000	9	887	8	0.0090192	0.8888889	GO:0043301	GO:BP	negative regulation of leukocyte degranulation	16175	10609	GO:00026….
query_1	TRUE	0.0000000	1098	887	109	0.1228861	0.0992714	GO:0043067	GO:BP	regulation of programmed cell death	16175	10513	GO:00125….
query_1	TRUE	0.0000000	57	887	18	0.0202931	0.3157895	GO:2000514	GO:BP	regulation of CD4-positive, alpha-beta T cell activation	16175	25817	GO:00357….
query_1	TRUE	0.0000000	45	887	16	0.0180383	0.3555556	GO:0032653	GO:BP	regulation of interleukin-10 production	16175	7700	GO:00018….
query_1	TRUE	0.0000000	45	887	16	0.0180383	0.3555556	GO:0032613	GO:BP	interleukin-10 production	16175	7661	GO:0001816
query_1	TRUE	0.0000000	181	887	33	0.0372041	0.1823204	GO:0050920	GO:BP	regulation of chemotaxis	16175	13362	GO:00069….
query_1	TRUE	0.0000000	79	887	21	0.0236753	0.2658228	GO:0042116	GO:BP	macrophage activation	16175	9972	GO:0002274
query_1	TRUE	0.0000000	2076	887	176	0.1984216	0.0847784	GO:0010557	GO:BP	positive regulation of macromolecule biosynthetic process	16175	4210	GO:00090….
query_1	TRUE	0.0000000	34	887	14	0.0157835	0.4117647	GO:0043300	GO:BP	regulation of leukocyte degranulation	16175	10608	GO:00026….
query_1	TRUE	0.0000000	24	887	12	0.0135287	0.5000000	GO:0036037	GO:BP	CD8-positive, alpha-beta T cell activation	16175	9403	GO:0046631
query_1	TRUE	0.0000000	72	887	20	0.0225479	0.2777778	GO:0032602	GO:BP	chemokine production	16175	7650	GO:0001816
query_1	TRUE	0.0000000	72	887	20	0.0225479	0.2777778	GO:0032642	GO:BP	regulation of chemokine production	16175	7689	GO:00018….
query_1	TRUE	0.0000000	95	887	23	0.0259301	0.2421053	GO:0002702	GO:BP	positive regulation of production of molecular mediator of immune response	16175	1220	GO:00024….
query_1	TRUE	0.0000000	283	887	43	0.0484780	0.1519435	GO:0010720	GO:BP	positive regulation of cell development	16175	4346	GO:00455….
query_1	TRUE	0.0000000	59	887	18	0.0202931	0.3050847	GO:0050766	GO:BP	positive regulation of phagocytosis	16175	13240	GO:00069….
query_1	TRUE	0.0000000	59	887	18	0.0202931	0.3050847	GO:0042093	GO:BP	T-helper cell differentiation	16175	9964	GO:0002294
query_1	TRUE	0.0000000	2938	887	231	0.2604284	0.0786249	GO:0048869	GO:BP	cellular developmental process	16175	13112	GO:00099….
query_1	TRUE	0.0000000	2938	887	231	0.2604284	0.0786249	GO:0030154	GO:BP	cell differentiation	16175	6687	GO:0048869
query_1	TRUE	0.0000000	7	887	7	0.0078918	1.0000000	GO:0002887	GO:BP	negative regulation of myeloid leukocyte mediated immunity	16175	1397	GO:00024….
query_1	TRUE	0.0000000	175	887	32	0.0360767	0.1828571	GO:0070374	GO:BP	positive regulation of ERK1 and ERK2 cascade	16175	16085	GO:00434….
query_1	TRUE	0.0000000	81	887	21	0.0236753	0.2592593	GO:0002690	GO:BP	positive regulation of leukocyte chemotaxis	16175	1208	GO:00026….
query_1	TRUE	0.0000000	53	887	17	0.0191657	0.3207547	GO:0046635	GO:BP	positive regulation of alpha-beta T cell activation	16175	12272	GO:00466….
query_1	TRUE	0.0000000	35	887	14	0.0157835	0.4000000	GO:0050856	GO:BP	regulation of T cell receptor signaling pathway	16175	13304	GO:00508….
query_1	TRUE	0.0000000	89	887	22	0.0248027	0.2471910	GO:0071347	GO:BP	cellular response to interleukin-1	16175	16599	GO:00705….
query_1	TRUE	0.0000000	89	887	22	0.0248027	0.2471910	GO:0002761	GO:BP	regulation of myeloid leukocyte differentiation	16175	1272	GO:00025….
query_1	TRUE	0.0000000	41	887	15	0.0169109	0.3658537	GO:0036230	GO:BP	granulocyte activation	16175	9504	GO:0002274
query_1	TRUE	0.0000000	25	887	12	0.0135287	0.4800000	GO:0002455	GO:BP	humoral immune response mediated by circulating immunoglobulin	16175	978	GO:00069….
query_1	TRUE	0.0000000	1616	887	144	0.1623450	0.0891089	GO:0070887	GO:BP	cellular response to chemical stimulus	16175	16358	GO:00422….
query_1	TRUE	0.0000000	25	887	12	0.0135287	0.4800000	GO:0019886	GO:BP	antigen processing and presentation of exogenous peptide antigen via MHC class II	16175	6064	GO:00024….
query_1	TRUE	0.0000000	1063	887	105	0.1183766	0.0987770	GO:0042981	GO:BP	regulation of apoptotic process	16175	10465	GO:00069….
query_1	TRUE	0.0000000	13	887	9	0.0101466	0.6923077	GO:0002399	GO:BP	MHC class II protein complex assembly	16175	923	GO:0002396
query_1	TRUE	0.0000000	13	887	9	0.0101466	0.6923077	GO:0002503	GO:BP	peptide antigen assembly with MHC class II protein complex	16175	1026	GO:00023….
query_1	TRUE	0.0000000	42	887	15	0.0169109	0.3571429	GO:0061756	GO:BP	leukocyte adhesion to vascular endothelial cell	16175	15650	GO:0007159
query_1	TRUE	0.0000000	21	887	11	0.0124014	0.5238095	GO:0002507	GO:BP	tolerance induction	16175	1029	GO:00023….
query_1	TRUE	0.0000001	450	887	57	0.0642616	0.1266667	GO:0030335	GO:BP	positive regulation of cell migration	16175	6781	GO:00164….
query_1	TRUE	0.0000001	239	887	38	0.0428410	0.1589958	GO:0070372	GO:BP	regulation of ERK1 and ERK2 cascade	16175	16083	GO:00434….
query_1	TRUE	0.0000001	31	887	13	0.0146561	0.4193548	GO:0043368	GO:BP	positive T cell selection	16175	10645	GO:0045058
query_1	TRUE	0.0000001	62	887	18	0.0202931	0.2903226	GO:0002532	GO:BP	production of molecular mediator involved in inflammatory response	16175	1054	GO:00069….
query_1	TRUE	0.0000001	92	887	22	0.0248027	0.2391304	GO:0002708	GO:BP	positive regulation of lymphocyte mediated immunity	16175	1226	GO:00024….
query_1	TRUE	0.0000001	979	887	98	0.1104848	0.1001021	GO:1901700	GO:BP	response to oxygen-containing compound	16175	21653	GO:0042221
query_1	TRUE	0.0000001	77	887	20	0.0225479	0.2597403	GO:0071677	GO:BP	positive regulation of mononuclear cell migration	16175	16850	GO:00026….
query_1	TRUE	0.0000001	479	887	59	0.0665163	0.1231733	GO:0040017	GO:BP	positive regulation of locomotion	16175	9905	GO:00400….
query_1	TRUE	0.0000001	1351	887	124	0.1397971	0.0917839	GO:0048585	GO:BP	negative regulation of response to stimulus	16175	12856	GO:00485….
query_1	TRUE	0.0000001	44	887	15	0.0169109	0.3409091	GO:0006911	GO:BP	phagocytosis, engulfment	16175	2561	GO:00069….
query_1	TRUE	0.0000001	44	887	15	0.0169109	0.3409091	GO:0043370	GO:BP	regulation of CD4-positive, alpha-beta T cell differentiation	16175	10647	GO:00433….
query_1	TRUE	0.0000001	44	887	15	0.0169109	0.3409091	GO:0002437	GO:BP	inflammatory response to antigenic stimulus	16175	960	GO:00069….
query_1	TRUE	0.0000001	44	887	15	0.0169109	0.3409091	GO:0001776	GO:BP	leukocyte homeostasis	16175	441	GO:00023….
query_1	TRUE	0.0000001	2156	887	178	0.2006764	0.0825603	GO:0009891	GO:BP	positive regulation of biosynthetic process	16175	3751	GO:00090….
query_1	TRUE	0.0000001	14	887	9	0.0101466	0.6428571	GO:0046629	GO:BP	gamma-delta T cell activation	16175	12266	GO:0042110
query_1	TRUE	0.0000001	33	887	13	0.0146561	0.3939394	GO:0070269	GO:BP	pyroptotic inflammatory response	16175	16029	GO:0006954
query_1	TRUE	0.0000001	96	887	22	0.0248027	0.2291667	GO:0002821	GO:BP	positive regulation of adaptive immune response	16175	1331	GO:00022….
query_1	TRUE	0.0000001	45	887	15	0.0169109	0.3333333	GO:0001913	GO:BP	T cell mediated cytotoxicity	16175	530	GO:00019….
query_1	TRUE	0.0000001	73	887	19	0.0214205	0.2602740	GO:0033627	GO:BP	cell adhesion mediated by integrin	16175	8328	GO:0007155
query_1	TRUE	0.0000001	73	887	19	0.0214205	0.2602740	GO:0071887	GO:BP	leukocyte apoptotic process	16175	16965	GO:0006915
query_1	TRUE	0.0000002	28	887	12	0.0135287	0.4285714	GO:0019883	GO:BP	antigen processing and presentation of endogenous antigen	16175	6061	GO:0019882
query_1	TRUE	0.0000002	59	887	17	0.0191657	0.2881356	GO:0045123	GO:BP	cellular extravasation	16175	11289	GO:0050900
query_1	TRUE	0.0000002	653	887	72	0.0811725	0.1102603	GO:0051050	GO:BP	positive regulation of transport	16175	13460	GO:00068….
query_1	TRUE	0.0000002	40	887	14	0.0157835	0.3500000	GO:0002715	GO:BP	regulation of natural killer cell mediated immunity	16175	1233	GO:00022….
query_1	TRUE	0.0000002	124	887	25	0.0281849	0.2016129	GO:0045807	GO:BP	positive regulation of endocytosis	16175	11631	GO:00068….
query_1	TRUE	0.0000002	124	887	25	0.0281849	0.2016129	GO:0051092	GO:BP	positive regulation of NF-kappaB transcription factor activity	16175	13487	GO:0051091
query_1	TRUE	0.0000002	53	887	16	0.0180383	0.3018868	GO:0150076	GO:BP	neuroinflammatory response	16175	20128	GO:0006954
query_1	TRUE	0.0000002	19	887	10	0.0112740	0.5263158	GO:0002710	GO:BP	negative regulation of T cell mediated immunity	16175	1228	GO:00024….
query_1	TRUE	0.0000002	19	887	10	0.0112740	0.5263158	GO:0001911	GO:BP	negative regulation of leukocyte mediated cytotoxicity	16175	528	GO:00019….
query_1	TRUE	0.0000002	470	887	57	0.0642616	0.1212766	GO:2000147	GO:BP	positive regulation of cell motility	16175	25495	GO:00400….
query_1	TRUE	0.0000002	99	887	22	0.0248027	0.2222222	GO:0045621	GO:BP	positive regulation of lymphocyte differentiation	16175	11472	GO:00300….
query_1	TRUE	0.0000003	47	887	15	0.0169109	0.3191489	GO:1900015	GO:BP	regulation of cytokine production involved in inflammatory response	16175	20326	GO:00018….
query_1	TRUE	0.0000003	47	887	15	0.0169109	0.3191489	GO:0002534	GO:BP	cytokine production involved in inflammatory response	16175	1056	GO:00018….
query_1	TRUE	0.0000003	24	887	11	0.0124014	0.4583333	GO:0010818	GO:BP	T cell chemotaxis	16175	4430	GO:00482….
query_1	TRUE	0.0000003	401	887	51	0.0574972	0.1271820	GO:0043068	GO:BP	positive regulation of programmed cell death	16175	10514	GO:00125….
query_1	TRUE	0.0000003	109	887	23	0.0259301	0.2110092	GO:0030183	GO:BP	B cell differentiation	16175	6700	GO:00300….
query_1	TRUE	0.0000004	770	887	80	0.0901917	0.1038961	GO:0048646	GO:BP	anatomical structure formation involved in morphogenesis	16175	12904	GO:00096….
query_1	TRUE	0.0000004	62	887	17	0.0191657	0.2741935	GO:0032757	GO:BP	positive regulation of interleukin-8 production	16175	7801	GO:00018….
query_1	TRUE	0.0000004	146	887	27	0.0304397	0.1849315	GO:0062207	GO:BP	regulation of pattern recognition receptor signaling pathway	16175	15863	GO:00022….
query_1	TRUE	0.0000004	55	887	16	0.0180383	0.2909091	GO:2000401	GO:BP	regulation of lymphocyte migration	16175	25716	GO:00716….
query_1	TRUE	0.0000004	42	887	14	0.0157835	0.3333333	GO:0001914	GO:BP	regulation of T cell mediated cytotoxicity	16175	531	GO:00019….
query_1	TRUE	0.0000004	280	887	40	0.0450958	0.1428571	GO:0007249	GO:BP	canonical NF-kappaB signal transduction	16175	2783	GO:0141124
query_1	TRUE	0.0000004	102	887	22	0.0248027	0.2156863	GO:0002832	GO:BP	negative regulation of response to biotic stimulus	16175	1342	GO:00028….
query_1	TRUE	0.0000004	20	887	10	0.0112740	0.5000000	GO:0006958	GO:BP	complement activation, classical pathway	16175	2589	GO:00024….
query_1	TRUE	0.0000004	25	887	11	0.0124014	0.4400000	GO:0050858	GO:BP	negative regulation of antigen receptor-mediated signaling pathway	16175	13306	GO:00026….
query_1	TRUE	0.0000004	138	887	26	0.0293123	0.1884058	GO:1903900	GO:BP	regulation of viral life cycle	16175	23367	GO:00190….
query_1	TRUE	0.0000005	56	887	16	0.0180383	0.2857143	GO:0002720	GO:BP	positive regulation of cytokine production involved in immune response	16175	1238	GO:00018….
query_1	TRUE	0.0000005	791	887	81	0.0913191	0.1024020	GO:1901701	GO:BP	cellular response to oxygen-containing compound	16175	21654	GO:00708….
query_1	TRUE	0.0000006	57	887	16	0.0180383	0.2807018	GO:2000106	GO:BP	regulation of leukocyte apoptotic process	16175	25457	GO:00429….
query_1	TRUE	0.0000007	170	887	29	0.0326945	0.1705882	GO:0010721	GO:BP	negative regulation of cell development	16175	4347	GO:00455….
query_1	TRUE	0.0000007	26	887	11	0.0124014	0.4230769	GO:0032743	GO:BP	positive regulation of interleukin-2 production	16175	7787	GO:00018….
query_1	TRUE	0.0000008	161	887	28	0.0315671	0.1739130	GO:0045637	GO:BP	regulation of myeloid cell differentiation	16175	11488	GO:00300….
query_1	TRUE	0.0000008	89	887	20	0.0225479	0.2247191	GO:0002824	GO:BP	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	16175	1334	GO:00024….
query_1	TRUE	0.0000008	1538	887	133	0.1499436	0.0864759	GO:0065009	GO:BP	regulation of molecular function	16175	15892	GO:0065007
query_1	TRUE	0.0000009	38	887	13	0.0146561	0.3421053	GO:0042269	GO:BP	regulation of natural killer cell mediated cytotoxicity	16175	10067	GO:00019….
query_1	TRUE	0.0000009	38	887	13	0.0146561	0.3421053	GO:0002886	GO:BP	regulation of myeloid leukocyte mediated immunity	16175	1396	GO:00024….
query_1	TRUE	0.0000009	32	887	12	0.0135287	0.3750000	GO:0009595	GO:BP	detection of biotic stimulus	16175	3526	GO:00096….
query_1	TRUE	0.0000010	74	887	18	0.0202931	0.2432432	GO:1901222	GO:BP	regulation of non-canonical NF-kappaB signal transduction	16175	21316	GO:00380….
query_1	TRUE	0.0000010	324	887	43	0.0484780	0.1327160	GO:0006816	GO:BP	calcium ion transport	16175	2495	GO:0030001
query_1	TRUE	0.0000011	52	887	15	0.0169109	0.2884615	GO:0099024	GO:BP	plasma membrane invagination	16175	19012	GO:0010324
query_1	TRUE	0.0000012	39	887	13	0.0146561	0.3333333	GO:0031663	GO:BP	lipopolysaccharide-mediated signaling pathway	16175	7267	GO:00071….
query_1	TRUE	0.0000012	39	887	13	0.0146561	0.3333333	GO:0002707	GO:BP	negative regulation of lymphocyte mediated immunity	16175	1225	GO:00024….
query_1	TRUE	0.0000012	13	887	8	0.0090192	0.6153846	GO:0002468	GO:BP	dendritic cell antigen processing and presentation	16175	991	GO:0019882
query_1	TRUE	0.0000013	22	887	10	0.0112740	0.4545455	GO:0031342	GO:BP	negative regulation of cell killing	16175	7133	GO:00019….
query_1	TRUE	0.0000013	33	887	12	0.0135287	0.3636364	GO:0042119	GO:BP	neutrophil activation	16175	9975	GO:0036230
query_1	TRUE	0.0000013	781	887	79	0.0890643	0.1011524	GO:0030334	GO:BP	regulation of cell migration	16175	6780	GO:00164….
query_1	TRUE	0.0000013	520	887	59	0.0665163	0.1134615	GO:0033993	GO:BP	response to lipid	16175	8371	GO:0042221
query_1	TRUE	0.0000016	4413	887	311	0.3506201	0.0704736	GO:0048519	GO:BP	negative regulation of biological process	16175	12802	GO:00081….
query_1	TRUE	0.0000016	119	887	23	0.0259301	0.1932773	GO:0050728	GO:BP	negative regulation of inflammatory response	16175	13227	GO:00069….
query_1	TRUE	0.0000017	28	887	11	0.0124014	0.3928571	GO:0050901	GO:BP	leukocyte tethering or rolling	16175	13343	GO:00451….
query_1	TRUE	0.0000018	129	887	24	0.0270575	0.1860465	GO:0007204	GO:BP	positive regulation of cytosolic calcium ion concentration	16175	2759	GO:0065008
query_1	TRUE	0.0000018	34	887	12	0.0135287	0.3529412	GO:0032715	GO:BP	negative regulation of interleukin-6 production	16175	7760	GO:00018….
query_1	TRUE	0.0000018	34	887	12	0.0135287	0.3529412	GO:0032735	GO:BP	positive regulation of interleukin-12 production	16175	7780	GO:00018….
query_1	TRUE	0.0000018	54	887	15	0.0169109	0.2777778	GO:0034113	GO:BP	heterotypic cell-cell adhesion	16175	8421	GO:0098609
query_1	TRUE	0.0000020	18	887	9	0.0101466	0.5000000	GO:0002396	GO:BP	MHC protein complex assembly	16175	920	GO:0065003
query_1	TRUE	0.0000020	18	887	9	0.0101466	0.5000000	GO:0002501	GO:BP	peptide antigen assembly with MHC protein complex	16175	1024	GO:00023….
query_1	TRUE	0.0000020	23	887	10	0.0112740	0.4347826	GO:0050869	GO:BP	negative regulation of B cell activation	16175	13317	GO:00421….
query_1	TRUE	0.0000020	23	887	10	0.0112740	0.4347826	GO:1901623	GO:BP	regulation of lymphocyte chemotaxis	16175	21603	GO:00026….
query_1	TRUE	0.0000022	221	887	33	0.0372041	0.1493213	GO:0030100	GO:BP	regulation of endocytosis	16175	6678	GO:00068….
query_1	TRUE	0.0000022	86	887	19	0.0214205	0.2209302	GO:0045582	GO:BP	positive regulation of T cell differentiation	16175	11433	GO:00302….
query_1	TRUE	0.0000023	41	887	13	0.0146561	0.3170732	GO:0002820	GO:BP	negative regulation of adaptive immune response	16175	1330	GO:00022….
query_1	TRUE	0.0000023	41	887	13	0.0146561	0.3170732	GO:0045576	GO:BP	mast cell activation	16175	11427	GO:0002274
query_1	TRUE	0.0000023	150	887	26	0.0293123	0.1733333	GO:0051897	GO:BP	positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	16175	13981	GO:00434….
query_1	TRUE	0.0000023	180	887	29	0.0326945	0.1611111	GO:0034612	GO:BP	response to tumor necrosis factor	16175	8690	GO:0034097
query_1	TRUE	0.0000024	160	887	27	0.0304397	0.1687500	GO:0050792	GO:BP	regulation of viral process	16175	13260	GO:00160….
query_1	TRUE	0.0000025	2767	887	210	0.2367531	0.0758945	GO:0010604	GO:BP	positive regulation of macromolecule metabolic process	16175	4251	GO:00098….
query_1	TRUE	0.0000029	123	887	23	0.0259301	0.1869919	GO:0019730	GO:BP	antimicrobial humoral response	16175	6021	GO:00069….
query_1	TRUE	0.0000030	56	887	15	0.0169109	0.2678571	GO:0032722	GO:BP	positive regulation of chemokine production	16175	7767	GO:00018….
query_1	TRUE	0.0000031	385	887	47	0.0529876	0.1220779	GO:0043065	GO:BP	positive regulation of apoptotic process	16175	10511	GO:00069….
query_1	TRUE	0.0000033	143	887	25	0.0281849	0.1748252	GO:0060759	GO:BP	regulation of response to cytokine stimulus	16175	14927	GO:00340….
query_1	TRUE	0.0000034	19	887	9	0.0101466	0.4736842	GO:0098543	GO:BP	detection of other organism	16175	18795	GO:00517….
query_1	TRUE	0.0000034	19	887	9	0.0101466	0.4736842	GO:0090023	GO:BP	positive regulation of neutrophil chemotaxis	16175	17957	GO:00305….
query_1	TRUE	0.0000034	115	887	22	0.0248027	0.1913043	GO:0030168	GO:BP	platelet activation	16175	6695	GO:00017….
query_1	TRUE	0.0000037	30	887	11	0.0124014	0.3666667	GO:0002260	GO:BP	lymphocyte homeostasis	16175	792	GO:0001776
query_1	TRUE	0.0000037	615	887	65	0.0732807	0.1056911	GO:0045597	GO:BP	positive regulation of cell differentiation	16175	11448	GO:00301….
query_1	TRUE	0.0000037	30	887	11	0.0124014	0.3666667	GO:0150077	GO:BP	regulation of neuroinflammatory response	16175	20129	GO:00507….
query_1	TRUE	0.0000038	57	887	15	0.0169109	0.2631579	GO:0050871	GO:BP	positive regulation of B cell activation	16175	13319	GO:00421….
query_1	TRUE	0.0000038	164	887	27	0.0304397	0.1646341	GO:0071356	GO:BP	cellular response to tumor necrosis factor	16175	16608	GO:00346….
query_1	TRUE	0.0000039	249	887	35	0.0394589	0.1405622	GO:0050878	GO:BP	regulation of body fluid levels	16175	13323	GO:0065008
query_1	TRUE	0.0000041	185	887	29	0.0326945	0.1567568	GO:0007599	GO:BP	hemostasis	16175	3058	GO:0050878
query_1	TRUE	0.0000042	175	887	28	0.0315671	0.1600000	GO:0050730	GO:BP	regulation of peptidyl-tyrosine phosphorylation	16175	13229	GO:00019….
query_1	TRUE	0.0000045	90	887	19	0.0214205	0.2111111	GO:0048525	GO:BP	negative regulation of viral process	16175	12808	GO:00160….
query_1	TRUE	0.0000048	740	887	74	0.0834273	0.1000000	GO:0098657	GO:BP	import into cell	16175	18813	GO:0006810
query_1	TRUE	0.0000049	25	887	10	0.0112740	0.4000000	GO:0002701	GO:BP	negative regulation of production of molecular mediator of immune response	16175	1219	GO:00024….
query_1	TRUE	0.0000049	25	887	10	0.0112740	0.4000000	GO:0098581	GO:BP	detection of external biotic stimulus	16175	18798	GO:00095….
query_1	TRUE	0.0000049	15	887	8	0.0090192	0.5333333	GO:0033003	GO:BP	regulation of mast cell activation	16175	7972	GO:00026….
query_1	TRUE	0.0000052	252	887	35	0.0394589	0.1388889	GO:0043122	GO:BP	regulation of canonical NF-kappaB signal transduction	16175	10541	GO:00072….
query_1	TRUE	0.0000053	31	887	11	0.0124014	0.3548387	GO:0032733	GO:BP	positive regulation of interleukin-10 production	16175	7778	GO:00018….
query_1	TRUE	0.0000053	31	887	11	0.0124014	0.3548387	GO:0030890	GO:BP	positive regulation of B cell proliferation	16175	6955	GO:00308….
query_1	TRUE	0.0000056	20	887	9	0.0101466	0.4500000	GO:0002825	GO:BP	regulation of T-helper 1 type immune response	16175	1335	GO:00028….
query_1	TRUE	0.0000056	20	887	9	0.0101466	0.4500000	GO:0050857	GO:BP	positive regulation of antigen receptor-mediated signaling pathway	16175	13305	GO:00099….
query_1	TRUE	0.0000056	20	887	9	0.0101466	0.4500000	GO:2001185	GO:BP	regulation of CD8-positive, alpha-beta T cell activation	16175	26385	GO:00360….
query_1	TRUE	0.0000059	854	887	82	0.0924464	0.0960187	GO:0040012	GO:BP	regulation of locomotion	16175	9900	GO:00400….
query_1	TRUE	0.0000060	59	887	15	0.0169109	0.2542373	GO:0010324	GO:BP	membrane invagination	16175	4060	GO:0061024
query_1	TRUE	0.0000061	407	887	48	0.0541150	0.1179361	GO:0009611	GO:BP	response to wounding	16175	3539	GO:0006950
query_1	TRUE	0.0000062	3045	887	225	0.2536640	0.0738916	GO:0009893	GO:BP	positive regulation of metabolic process	16175	3753	GO:00081….
query_1	TRUE	0.0000062	75	887	17	0.0191657	0.2266667	GO:0030101	GO:BP	natural killer cell activation	16175	6679	GO:0046649
query_1	TRUE	0.0000063	4632	887	320	0.3607666	0.0690846	GO:0032502	GO:BP	developmental process	16175	7612	GO:0008150
query_1	TRUE	0.0000065	408	887	48	0.0541150	0.1176471	GO:0071396	GO:BP	cellular response to lipid	16175	16648	GO:00339….
query_1	TRUE	0.0000065	179	887	28	0.0315671	0.1564246	GO:0007596	GO:BP	blood coagulation	16175	3055	GO:00075….
query_1	TRUE	0.0000065	38	887	12	0.0135287	0.3157895	GO:2000404	GO:BP	regulation of T cell migration	16175	25719	GO:00726….
query_1	TRUE	0.0000069	149	887	25	0.0281849	0.1677852	GO:0002753	GO:BP	cytoplasmic pattern recognition receptor signaling pathway	16175	1264	GO:00022….
query_1	TRUE	0.0000069	409	887	48	0.0541150	0.1173594	GO:0060627	GO:BP	regulation of vesicle-mediated transport	16175	14803	GO:00161….
query_1	TRUE	0.0000072	831	887	80	0.0901917	0.0962696	GO:2000145	GO:BP	regulation of cell motility	16175	25493	GO:00400….
query_1	TRUE	0.0000074	102	887	20	0.0225479	0.1960784	GO:0038061	GO:BP	non-canonical NF-kappaB signal transduction	16175	9680	GO:0141124
query_1	TRUE	0.0000074	32	887	11	0.0124014	0.3437500	GO:0045066	GO:BP	regulatory T cell differentiation	16175	11264	GO:0030217
query_1	TRUE	0.0000076	916	887	86	0.0969560	0.0938865	GO:0044093	GO:BP	positive regulation of molecular function	16175	10915	GO:0065009
query_1	TRUE	0.0000085	131	887	23	0.0259301	0.1755725	GO:0050731	GO:BP	positive regulation of peptidyl-tyrosine phosphorylation	16175	13230	GO:00019….
query_1	TRUE	0.0000087	161	887	26	0.0293123	0.1614907	GO:0045055	GO:BP	regulated exocytosis	16175	11253	GO:0006887
query_1	TRUE	0.0000088	8	887	6	0.0067644	0.7500000	GO:0002579	GO:BP	positive regulation of antigen processing and presentation	16175	1100	GO:00025….
query_1	TRUE	0.0000088	8	887	6	0.0067644	0.7500000	GO:0098883	GO:BP	synapse pruning	16175	18928	GO:00508….
query_1	TRUE	0.0000097	204	887	30	0.0338219	0.1470588	GO:0051896	GO:BP	regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	16175	13980	GO:00434….
query_1	TRUE	0.0000100	183	887	28	0.0315671	0.1530055	GO:0050817	GO:BP	coagulation	16175	13279	GO:0032501
query_1	TRUE	0.0000103	33	887	11	0.0124014	0.3333333	GO:0002448	GO:BP	mast cell mediated immunity	16175	971	GO:0002444
query_1	TRUE	0.0000103	33	887	11	0.0124014	0.3333333	GO:0045622	GO:BP	regulation of T-helper cell differentiation	16175	11473	GO:00026….
query_1	TRUE	0.0000106	54	887	14	0.0157835	0.2592593	GO:0060760	GO:BP	positive regulation of response to cytokine stimulus	16175	14928	GO:00340….
query_1	TRUE	0.0000106	78	887	17	0.0191657	0.2179487	GO:0045824	GO:BP	negative regulation of innate immune response	16175	11644	GO:00028….
query_1	TRUE	0.0000106	54	887	14	0.0157835	0.2592593	GO:0045071	GO:BP	negative regulation of viral genome replication	16175	11269	GO:00190….
query_1	TRUE	0.0000107	27	887	10	0.0112740	0.3703704	GO:0038094	GO:BP	Fc-gamma receptor signaling pathway	16175	9694	GO:0038093
query_1	TRUE	0.0000115	12	887	7	0.0078918	0.5833333	GO:0002643	GO:BP	regulation of tolerance induction	16175	1161	GO:00025….
query_1	TRUE	0.0000142	22	887	9	0.0101466	0.4090909	GO:0032703	GO:BP	negative regulation of interleukin-2 production	16175	7748	GO:00018….
query_1	TRUE	0.0000142	22	887	9	0.0101466	0.4090909	GO:0071624	GO:BP	positive regulation of granulocyte chemotaxis	16175	16804	GO:00026….
query_1	TRUE	0.0000142	34	887	11	0.0124014	0.3235294	GO:2000403	GO:BP	positive regulation of lymphocyte migration	16175	25718	GO:00716….
query_1	TRUE	0.0000142	34	887	11	0.0124014	0.3235294	GO:0001774	GO:BP	microglial cell activation	16175	439	GO:00022….
query_1	TRUE	0.0000142	34	887	11	0.0124014	0.3235294	GO:0002269	GO:BP	leukocyte activation involved in inflammatory response	16175	801	GO:00069….
query_1	TRUE	0.0000155	17	887	8	0.0090192	0.4705882	GO:1903306	GO:BP	negative regulation of regulated secretory pathway	16175	22893	GO:00450….
query_1	TRUE	0.0000155	947	887	87	0.0980834	0.0918691	GO:0050790	GO:BP	regulation of catalytic activity	16175	13259	GO:0065009
query_1	TRUE	0.0000155	28	887	10	0.0112740	0.3571429	GO:0045589	GO:BP	regulation of regulatory T cell differentiation	16175	11440	GO:00450….
query_1	TRUE	0.0000166	1253	887	108	0.1217587	0.0861931	GO:0051049	GO:BP	regulation of transport	16175	13459	GO:00068….
query_1	TRUE	0.0000192	49	887	13	0.0146561	0.2653061	GO:1903556	GO:BP	negative regulation of tumor necrosis factor superfamily cytokine production	16175	23103	GO:00018….
query_1	TRUE	0.0000210	57	887	14	0.0157835	0.2456140	GO:0002711	GO:BP	positive regulation of T cell mediated immunity	16175	1229	GO:00024….
query_1	TRUE	0.0000223	29	887	10	0.0112740	0.3448276	GO:0042092	GO:BP	type 2 immune response	16175	9963	GO:0006955
query_1	TRUE	0.0000227	235	887	32	0.0360767	0.1361702	GO:0043491	GO:BP	phosphatidylinositol 3-kinase/protein kinase B signal transduction	16175	10736	GO:0141124
query_1	TRUE	0.0000230	13	887	7	0.0078918	0.5384615	GO:0032695	GO:BP	negative regulation of interleukin-12 production	16175	7741	GO:00018….
query_1	TRUE	0.0000239	9	887	6	0.0067644	0.6666667	GO:0035747	GO:BP	natural killer cell chemotaxis	16175	9212	GO:0048247
query_1	TRUE	0.0000239	9	887	6	0.0067644	0.6666667	GO:2001187	GO:BP	positive regulation of CD8-positive, alpha-beta T cell activation	16175	26387	GO:00360….
query_1	TRUE	0.0000239	74	887	16	0.0180383	0.2162162	GO:0030316	GO:BP	osteoclast differentiation	16175	6767	GO:0002573
query_1	TRUE	0.0000242	50	887	13	0.0146561	0.2600000	GO:1901224	GO:BP	positive regulation of non-canonical NF-kappaB signal transduction	16175	21318	GO:00380….
query_1	TRUE	0.0000253	101	887	19	0.0214205	0.1881188	GO:0051209	GO:BP	release of sequestered calcium ion into cytosol	16175	13568	GO:00512….
query_1	TRUE	0.0000258	18	887	8	0.0090192	0.4444444	GO:0140131	GO:BP	positive regulation of lymphocyte chemotaxis	16175	19677	GO:00026….
query_1	TRUE	0.0000261	36	887	11	0.0124014	0.3055556	GO:0002823	GO:BP	negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	16175	1333	GO:00024….
query_1	TRUE	0.0000293	102	887	19	0.0214205	0.1862745	GO:0051283	GO:BP	negative regulation of sequestering of calcium ion	16175	13619	GO:00485….
query_1	TRUE	0.0000311	30	887	10	0.0112740	0.3333333	GO:0072677	GO:BP	eosinophil migration	16175	17495	GO:0097530
query_1	TRUE	0.0000319	59	887	14	0.0157835	0.2372881	GO:0030239	GO:BP	myofibril assembly	16175	6736	GO:00109….
query_1	TRUE	0.0000336	132	887	22	0.0248027	0.1666667	GO:0001959	GO:BP	regulation of cytokine-mediated signaling pathway	16175	568	GO:00099….
query_1	TRUE	0.0000339	103	887	19	0.0214205	0.1844660	GO:0051282	GO:BP	regulation of sequestering of calcium ion	16175	13618	GO:00328….
query_1	TRUE	0.0000340	44	887	12	0.0135287	0.2727273	GO:0043030	GO:BP	regulation of macrophage activation	16175	10485	GO:00026….
query_1	TRUE	0.0000346	37	887	11	0.0124014	0.2972973	GO:0061900	GO:BP	glial cell activation	16175	15715	GO:00017….
query_1	TRUE	0.0000346	37	887	11	0.0124014	0.2972973	GO:0046638	GO:BP	positive regulation of alpha-beta T cell differentiation	16175	12275	GO:00455….
query_1	TRUE	0.0000346	37	887	11	0.0124014	0.2972973	GO:0002762	GO:BP	negative regulation of myeloid leukocyte differentiation	16175	1273	GO:00025….
query_1	TRUE	0.0000346	263	887	34	0.0383315	0.1292776	GO:0006887	GO:BP	exocytosis	16175	2543	GO:00161….
query_1	TRUE	0.0000351	85	887	17	0.0191657	0.2000000	GO:0002220	GO:BP	innate immune response activating cell surface receptor signaling pathway	16175	754	GO:00024….
query_1	TRUE	0.0000398	175	887	26	0.0293123	0.1485714	GO:0051146	GO:BP	striated muscle cell differentiation	16175	13529	GO:0042692
query_1	TRUE	0.0000416	3144	887	226	0.2547914	0.0718830	GO:0007275	GO:BP	multicellular organism development	16175	2802	GO:00325….
query_1	TRUE	0.0000419	14	887	7	0.0078918	0.5000000	GO:0045063	GO:BP	T-helper 1 cell differentiation	16175	11261	GO:00420….
query_1	TRUE	0.0000419	14	887	7	0.0078918	0.5000000	GO:0010819	GO:BP	regulation of T cell chemotaxis	16175	4431	GO:00108….
query_1	TRUE	0.0000466	25	887	9	0.0101466	0.3600000	GO:1902624	GO:BP	positive regulation of neutrophil migration	16175	22395	GO:00026….
query_1	TRUE	0.0000468	145	887	23	0.0259301	0.1586207	GO:0048872	GO:BP	homeostasis of number of cells	16175	13115	GO:0048871
query_1	TRUE	0.0000473	61	887	14	0.0157835	0.2295082	GO:0002526	GO:BP	acute inflammatory response	16175	1048	GO:0006954
query_1	TRUE	0.0000474	339	887	40	0.0450958	0.1179941	GO:0042060	GO:BP	wound healing	16175	9947	GO:0009611
query_1	TRUE	0.0000512	106	887	19	0.0214205	0.1792453	GO:0051208	GO:BP	sequestering of calcium ion	16175	13567	GO:00068….
query_1	TRUE	0.0000539	10	887	6	0.0067644	0.6000000	GO:0002524	GO:BP	hypersensitivity	16175	1046	GO:0002438
query_1	TRUE	0.0000539	10	887	6	0.0067644	0.6000000	GO:0002517	GO:BP	T cell tolerance induction	16175	1039	GO:0002507
query_1	TRUE	0.0000575	62	887	14	0.0157835	0.2258065	GO:0070527	GO:BP	platelet aggregation	16175	16166	GO:00301….
query_1	TRUE	0.0000577	32	887	10	0.0112740	0.3125000	GO:0043303	GO:BP	mast cell degranulation	16175	10611	GO:00022….
query_1	TRUE	0.0000577	32	887	10	0.0112740	0.3125000	GO:2000116	GO:BP	regulation of cysteine-type endopeptidase activity	16175	25465	GO:0052548
query_1	TRUE	0.0000594	39	887	11	0.0124014	0.2820513	GO:0141084	GO:BP	inflammasome-mediated signaling pathway	16175	20015	GO:00027….
query_1	TRUE	0.0000635	20	887	8	0.0090192	0.4000000	GO:0002475	GO:BP	antigen processing and presentation via MHC class Ib	16175	998	GO:0019882
query_1	TRUE	0.0000635	20	887	8	0.0090192	0.4000000	GO:0002295	GO:BP	T-helper cell lineage commitment	16175	827	GO:00420….
query_1	TRUE	0.0000644	510	887	53	0.0597520	0.1039216	GO:0048871	GO:BP	multicellular organismal-level homeostasis	16175	13114	GO:00325….
query_1	TRUE	0.0000660	26	887	9	0.0101466	0.3461538	GO:0090022	GO:BP	regulation of neutrophil chemotaxis	16175	17956	GO:00305….
query_1	TRUE	0.0000687	47	887	12	0.0135287	0.2553191	GO:0038093	GO:BP	Fc receptor signaling pathway	16175	9693	GO:0002768
query_1	TRUE	0.0000687	47	887	12	0.0135287	0.2553191	GO:0042130	GO:BP	negative regulation of T cell proliferation	16175	9984	GO:00420….
query_1	TRUE	0.0000687	47	887	12	0.0135287	0.2553191	GO:0001961	GO:BP	positive regulation of cytokine-mediated signaling pathway	16175	570	GO:00019….
query_1	TRUE	0.0000717	192	887	27	0.0304397	0.1406250	GO:0043123	GO:BP	positive regulation of canonical NF-kappaB signal transduction	16175	10542	GO:00072….
query_1	TRUE	0.0000720	15	887	7	0.0078918	0.4666667	GO:0002438	GO:BP	acute inflammatory response to antigenic stimulus	16175	961	GO:00024….
query_1	TRUE	0.0000768	33	887	10	0.0112740	0.3030303	GO:0002279	GO:BP	mast cell activation involved in immune response	16175	811	GO:00022….
query_1	TRUE	0.0000768	33	887	10	0.0112740	0.3030303	GO:2000516	GO:BP	positive regulation of CD4-positive, alpha-beta T cell activation	16175	25819	GO:00357….
query_1	TRUE	0.0000768	33	887	10	0.0112740	0.3030303	GO:0002474	GO:BP	antigen processing and presentation of peptide antigen via MHC class I	16175	997	GO:0048002
query_1	TRUE	0.0000825	4217	887	288	0.3246900	0.0682950	GO:0048523	GO:BP	negative regulation of cellular process	16175	12806	GO:00099….
query_1	TRUE	0.0000859	48	887	12	0.0135287	0.2500000	GO:0070227	GO:BP	lymphocyte apoptotic process	16175	15997	GO:0071887
query_1	TRUE	0.0000897	963	887	85	0.0958286	0.0882658	GO:0051094	GO:BP	positive regulation of developmental process	16175	13489	GO:00325….
query_1	TRUE	0.0000919	27	887	9	0.0101466	0.3333333	GO:0048245	GO:BP	eosinophil chemotaxis	16175	12603	GO:00716….
query_1	TRUE	0.0000919	27	887	9	0.0101466	0.3333333	GO:0002717	GO:BP	positive regulation of natural killer cell mediated immunity	16175	1235	GO:00022….
query_1	TRUE	0.0000978	41	887	11	0.0124014	0.2682927	GO:0033628	GO:BP	regulation of cell adhesion mediated by integrin	16175	8329	GO:00301….
query_1	TRUE	0.0000997	4	887	4	0.0045096	1.0000000	GO:0002586	GO:BP	regulation of antigen processing and presentation of peptide antigen via MHC class II	16175	1107	GO:00024….
query_1	TRUE	0.0000997	4	887	4	0.0045096	1.0000000	GO:0150062	GO:BP	complement-mediated synapse pruning	16175	20118	GO:0098883
query_1	TRUE	0.0001015	34	887	10	0.0112740	0.2941176	GO:0001916	GO:BP	positive regulation of T cell mediated cytotoxicity	16175	533	GO:00019….
query_1	TRUE	0.0001015	34	887	10	0.0112740	0.2941176	GO:1902622	GO:BP	regulation of neutrophil migration	16175	22393	GO:00026….
query_1	TRUE	0.0001033	7	887	5	0.0056370	0.7142857	GO:2000501	GO:BP	regulation of natural killer cell chemotaxis	16175	25807	GO:00357….
query_1	TRUE	0.0001033	7	887	5	0.0056370	0.7142857	GO:0002645	GO:BP	positive regulation of tolerance induction	16175	1163	GO:00025….
query_1	TRUE	0.0001033	7	887	5	0.0056370	0.7142857	GO:0001915	GO:BP	negative regulation of T cell mediated cytotoxicity	16175	532	GO:00019….
query_1	TRUE	0.0001041	142	887	22	0.0248027	0.1549296	GO:0007259	GO:BP	cell surface receptor signaling pathway via JAK-STAT	16175	2789	GO:0097696
query_1	TRUE	0.0001056	49	887	12	0.0135287	0.2448980	GO:0045670	GO:BP	regulation of osteoclast differentiation	16175	11521	GO:00027….
query_1	TRUE	0.0001065	11	887	6	0.0067644	0.5454545	GO:0043374	GO:BP	CD8-positive, alpha-beta T cell differentiation	16175	10651	GO:00360….
query_1	TRUE	0.0001173	16	887	7	0.0078918	0.4375000	GO:0060263	GO:BP	regulation of respiratory burst	16175	14480	GO:00192….
query_1	TRUE	0.0001173	16	887	7	0.0078918	0.4375000	GO:0016045	GO:BP	detection of bacterium	16175	5078	GO:00096….
query_1	TRUE	0.0001220	103	887	18	0.0202931	0.1747573	GO:0002520	GO:BP	immune system development	16175	1042	GO:00023….
query_1	TRUE	0.0001220	103	887	18	0.0202931	0.1747573	GO:0055002	GO:BP	striated muscle cell development	16175	14191	GO:00511….
query_1	TRUE	0.0001225	42	887	11	0.0124014	0.2619048	GO:0071622	GO:BP	regulation of granulocyte chemotaxis	16175	16802	GO:00026….
query_1	TRUE	0.0001250	28	887	9	0.0101466	0.3214286	GO:2000406	GO:BP	positive regulation of T cell migration	16175	25721	GO:00726….
query_1	TRUE	0.0001374	22	887	8	0.0090192	0.3636364	GO:0002483	GO:BP	antigen processing and presentation of endogenous peptide antigen	16175	1006	GO:00198….
query_1	TRUE	0.0001392	67	887	14	0.0157835	0.2089552	GO:0002752	GO:BP	cell surface pattern recognition receptor signaling pathway	16175	1263	GO:00022….
query_1	TRUE	0.0001397	85	887	16	0.0180383	0.1882353	GO:0034109	GO:BP	homotypic cell-cell adhesion	16175	8417	GO:0098609
query_1	TRUE	0.0001576	345	887	39	0.0439684	0.1130435	GO:0051090	GO:BP	regulation of DNA-binding transcription factor activity	16175	13485	GO:00063….
query_1	TRUE	0.0001703	29	887	9	0.0101466	0.3103448	GO:0032689	GO:BP	negative regulation of type II interferon production	16175	7735	GO:00018….
query_1	TRUE	0.0001703	29	887	9	0.0101466	0.3103448	GO:0072539	GO:BP	T-helper 17 cell differentiation	16175	17437	GO:00420….
query_1	TRUE	0.0001703	29	887	9	0.0101466	0.3103448	GO:0045920	GO:BP	negative regulation of exocytosis	16175	11714	GO:00068….
query_1	TRUE	0.0001714	36	887	10	0.0112740	0.2777778	GO:0140632	GO:BP	canonical inflammasome complex assembly	16175	19839	GO:00650….
query_1	TRUE	0.0001714	36	887	10	0.0112740	0.2777778	GO:0070228	GO:BP	regulation of lymphocyte apoptotic process	16175	15998	GO:00702….
query_1	TRUE	0.0001794	249	887	31	0.0349493	0.1244980	GO:0070588	GO:BP	calcium ion transmembrane transport	16175	16193	GO:00068….
query_1	TRUE	0.0001833	17	887	7	0.0078918	0.4117647	GO:0001562	GO:BP	response to protozoan	16175	351	GO:0051707
query_1	TRUE	0.0001833	17	887	7	0.0078918	0.4117647	GO:0001773	GO:BP	myeloid dendritic cell activation	16175	438	GO:0002274
query_1	TRUE	0.0001833	17	887	7	0.0078918	0.4117647	GO:0032753	GO:BP	positive regulation of interleukin-4 production	16175	7797	GO:00018….
query_1	TRUE	0.0001833	60	887	13	0.0146561	0.2166667	GO:0140895	GO:BP	cell surface toll-like receptor signaling pathway	16175	19927	GO:0002752
query_1	TRUE	0.0001833	17	887	7	0.0078918	0.4117647	GO:0002862	GO:BP	negative regulation of inflammatory response to antigenic stimulus	16175	1372	GO:00024….
query_1	TRUE	0.0001833	17	887	7	0.0078918	0.4117647	GO:0042832	GO:BP	defense response to protozoan	16175	10388	GO:00015….
query_1	TRUE	0.0001929	12	887	6	0.0067644	0.5000000	GO:0032490	GO:BP	detection of molecule of bacterial origin	16175	7601	GO:00022….
query_1	TRUE	0.0001929	23	887	8	0.0090192	0.3478261	GO:0002363	GO:BP	alpha-beta T cell lineage commitment	16175	895	GO:00023….
query_1	TRUE	0.0001929	12	887	6	0.0067644	0.5000000	GO:0030889	GO:BP	negative regulation of B cell proliferation	16175	6954	GO:00308….
query_1	TRUE	0.0001929	23	887	8	0.0090192	0.3478261	GO:0045577	GO:BP	regulation of B cell differentiation	16175	11428	GO:00301….
query_1	TRUE	0.0001929	23	887	8	0.0090192	0.3478261	GO:0043373	GO:BP	CD4-positive, alpha-beta T cell lineage commitment	16175	10650	GO:00023….
query_1	TRUE	0.0001929	12	887	6	0.0067644	0.5000000	GO:0070486	GO:BP	leukocyte aggregation	16175	16147	GO:0007159
query_1	TRUE	0.0001929	12	887	6	0.0067644	0.5000000	GO:1903975	GO:BP	regulation of glial cell migration	16175	23432	GO:00083….
query_1	TRUE	0.0002003	107	887	18	0.0202931	0.1682243	GO:0051048	GO:BP	negative regulation of secretion	16175	13458	GO:00469….
query_1	TRUE	0.0002139	149	887	22	0.0248027	0.1476510	GO:0097696	GO:BP	cell surface receptor signaling pathway via STAT	16175	18727	GO:0007166
query_1	TRUE	0.0002168	37	887	10	0.0112740	0.2702703	GO:0072538	GO:BP	T-helper 17 type immune response	16175	17436	GO:0002460
query_1	TRUE	0.0002169	160	887	23	0.0259301	0.1437500	GO:0097553	GO:BP	calcium ion transmembrane import into cytosol	16175	18700	GO:0070588
query_1	TRUE	0.0002227	30	887	9	0.0101466	0.3000000	GO:0046633	GO:BP	alpha-beta T cell proliferation	16175	12270	GO:00420….
query_1	TRUE	0.0002227	30	887	9	0.0101466	0.3000000	GO:0002431	GO:BP	Fc receptor mediated stimulatory signaling pathway	16175	954	GO:0002429
query_1	TRUE	0.0002289	522	887	52	0.0586246	0.0996169	GO:0042327	GO:BP	positive regulation of phosphorylation	16175	10095	GO:00163….
query_1	TRUE	0.0002330	1259	887	103	0.1161218	0.0818110	GO:0016192	GO:BP	vesicle-mediated transport	16175	5168	GO:00068….
query_1	TRUE	0.0002424	564	887	55	0.0620068	0.0975177	GO:0045937	GO:BP	positive regulation of phosphate metabolic process	16175	11731	GO:00067….
query_1	TRUE	0.0002424	564	887	55	0.0620068	0.0975177	GO:0010562	GO:BP	positive regulation of phosphorus metabolic process	16175	4215	GO:00067….
query_1	TRUE	0.0002427	8	887	5	0.0056370	0.6250000	GO:0002664	GO:BP	regulation of T cell tolerance induction	16175	1182	GO:00025….
query_1	TRUE	0.0002427	8	887	5	0.0056370	0.6250000	GO:0140507	GO:BP	granzyme-mediated programmed cell death signaling pathway	16175	19803	GO:00071….
query_1	TRUE	0.0002427	8	887	5	0.0056370	0.6250000	GO:2001198	GO:BP	regulation of dendritic cell differentiation	16175	26398	GO:00970….
query_1	TRUE	0.0002561	80	887	15	0.0169109	0.1875000	GO:0045069	GO:BP	regulation of viral genome replication	16175	11267	GO:00190….
query_1	TRUE	0.0002670	24	887	8	0.0090192	0.3333333	GO:0031664	GO:BP	regulation of lipopolysaccharide-mediated signaling pathway	16175	7268	GO:00028….
query_1	TRUE	0.0002670	24	887	8	0.0090192	0.3333333	GO:2000515	GO:BP	negative regulation of CD4-positive, alpha-beta T cell activation	16175	25818	GO:00357….
query_1	TRUE	0.0002670	24	887	8	0.0090192	0.3333333	GO:0002360	GO:BP	T cell lineage commitment	16175	892	GO:00302….
query_1	TRUE	0.0002670	24	887	8	0.0090192	0.3333333	GO:0043369	GO:BP	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment	16175	10646	GO:00023….
query_1	TRUE	0.0002716	243	887	30	0.0338219	0.1234568	GO:1901342	GO:BP	regulation of vasculature development	16175	21401	GO:00019….
query_1	TRUE	0.0002724	18	887	7	0.0078918	0.3888889	GO:0072540	GO:BP	T-helper 17 cell lineage commitment	16175	17438	GO:00022….
query_1	TRUE	0.0002724	18	887	7	0.0078918	0.3888889	GO:0002755	GO:BP	MyD88-dependent toll-like receptor signaling pathway	16175	1266	GO:0002224
query_1	TRUE	0.0002895	500	887	50	0.0563698	0.1000000	GO:0001934	GO:BP	positive regulation of protein phosphorylation	16175	548	GO:00019….
query_1	TRUE	0.0003046	501	887	50	0.0563698	0.0998004	GO:0008285	GO:BP	negative regulation of cell population proliferation	16175	3152	GO:00082….
query_1	TRUE	0.0003135	233	887	29	0.0326945	0.1244635	GO:0006874	GO:BP	intracellular calcium ion homeostasis	16175	2532	GO:00300….
query_1	TRUE	0.0003159	1608	887	125	0.1409245	0.0777363	GO:0032879	GO:BP	regulation of localization	16175	7876	GO:00507….
query_1	TRUE	0.0003262	13	887	6	0.0067644	0.4615385	GO:0002827	GO:BP	positive regulation of T-helper 1 type immune response	16175	1337	GO:00028….
query_1	TRUE	0.0003262	13	887	6	0.0067644	0.4615385	GO:0010820	GO:BP	positive regulation of T cell chemotaxis	16175	4432	GO:00108….
query_1	TRUE	0.0003542	47	887	11	0.0124014	0.2340426	GO:0032720	GO:BP	negative regulation of tumor necrosis factor production	16175	7765	GO:00326….
query_1	TRUE	0.0003671	25	887	8	0.0090192	0.3200000	GO:0002861	GO:BP	regulation of inflammatory response to antigenic stimulus	16175	1371	GO:00024….
query_1	TRUE	0.0003778	32	887	9	0.0101466	0.2812500	GO:0002724	GO:BP	regulation of T cell cytokine production	16175	1242	GO:00023….
query_1	TRUE	0.0003778	887	887	77	0.0868095	0.0868095	GO:0051174	GO:BP	regulation of phosphorus metabolic process	16175	13554	GO:00067….
query_1	TRUE	0.0003778	887	887	77	0.0868095	0.0868095	GO:0019220	GO:BP	regulation of phosphate metabolic process	16175	5597	GO:00067….
query_1	TRUE	0.0003778	32	887	9	0.0101466	0.2812500	GO:0002369	GO:BP	T cell cytokine production	16175	901	GO:00023….
query_1	TRUE	0.0004008	19	887	7	0.0078918	0.3684211	GO:0043029	GO:BP	T cell homeostasis	16175	10484	GO:0002260
query_1	TRUE	0.0004008	19	887	7	0.0078918	0.3684211	GO:1900017	GO:BP	positive regulation of cytokine production involved in inflammatory response	16175	20328	GO:00018….
query_1	TRUE	0.0004008	19	887	7	0.0078918	0.3684211	GO:0050860	GO:BP	negative regulation of T cell receptor signaling pathway	16175	13308	GO:00508….
query_1	TRUE	0.0004023	617	887	58	0.0653890	0.0940032	GO:0051093	GO:BP	negative regulation of developmental process	16175	13488	GO:00325….
query_1	TRUE	0.0004058	93	887	16	0.0180383	0.1720430	GO:0051928	GO:BP	positive regulation of calcium ion transport	16175	13999	GO:00068….
query_1	TRUE	0.0004088	103	887	17	0.0191657	0.1650485	GO:0039531	GO:BP	regulation of cytoplasmic pattern recognition receptor signaling pathway	16175	9804	GO:00027….
query_1	TRUE	0.0004124	5	887	4	0.0045096	0.8000000	GO:2000503	GO:BP	positive regulation of natural killer cell chemotaxis	16175	25809	GO:00357….
query_1	TRUE	0.0004124	5	887	4	0.0045096	0.8000000	GO:0090634	GO:BP	microglial cell mediated cytotoxicity	16175	18380	GO:00019….
query_1	TRUE	0.0004124	65	887	13	0.0146561	0.2000000	GO:0007260	GO:BP	tyrosine phosphorylation of STAT protein	16175	2790	GO:00072….
query_1	TRUE	0.0004124	5	887	4	0.0045096	0.8000000	GO:2000523	GO:BP	regulation of T cell costimulation	16175	25826	GO:00312….
query_1	TRUE	0.0004124	5	887	4	0.0045096	0.8000000	GO:0043378	GO:BP	positive regulation of CD8-positive, alpha-beta T cell differentiation	16175	10655	GO:00433….
query_1	TRUE	0.0004124	5	887	4	0.0045096	0.8000000	GO:1904149	GO:BP	regulation of microglial cell mediated cytotoxicity	16175	23570	GO:00019….
query_1	TRUE	0.0004124	5	887	4	0.0045096	0.8000000	GO:0002580	GO:BP	regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	16175	1101	GO:00025….
query_1	TRUE	0.0004124	5	887	4	0.0045096	0.8000000	GO:0031394	GO:BP	positive regulation of prostaglandin biosynthetic process	16175	7151	GO:00015….
query_1	TRUE	0.0004133	237	887	29	0.0326945	0.1223629	GO:0045765	GO:BP	regulation of angiogenesis	16175	11601	GO:00015….
query_1	TRUE	0.0004133	632	887	59	0.0665163	0.0933544	GO:0030036	GO:BP	actin cytoskeleton organization	16175	6660	GO:00070….
query_1	TRUE	0.0004193	40	887	10	0.0112740	0.2500000	GO:0050691	GO:BP	regulation of defense response to virus by host	16175	13221	GO:0050688
query_1	TRUE	0.0004193	40	887	10	0.0112740	0.2500000	GO:0045620	GO:BP	negative regulation of lymphocyte differentiation	16175	11471	GO:00300….
query_1	TRUE	0.0004195	48	887	11	0.0124014	0.2291667	GO:0071260	GO:BP	cellular response to mechanical stimulus	16175	16518	GO:00096….
query_1	TRUE	0.0004195	48	887	11	0.0124014	0.2291667	GO:0071496	GO:BP	cellular response to external stimulus	16175	16729	GO:0009605
query_1	TRUE	0.0004270	179	887	24	0.0270575	0.1340782	GO:0051924	GO:BP	regulation of calcium ion transport	16175	13997	GO:00068….
query_1	TRUE	0.0004372	135	887	20	0.0225479	0.1481481	GO:0051260	GO:BP	protein homooligomerization	16175	13607	GO:0051259
query_1	TRUE	0.0004663	649	887	60	0.0676437	0.0924499	GO:0046903	GO:BP	secretion	16175	12430	GO:0006810
query_1	TRUE	0.0004676	443	887	45	0.0507328	0.1015801	GO:0043549	GO:BP	regulation of kinase activity	16175	10763	GO:00423….
query_1	TRUE	0.0004703	792	887	70	0.0789177	0.0883838	GO:0042325	GO:BP	regulation of phosphorylation	16175	10093	GO:00163….
query_1	TRUE	0.0004740	33	887	9	0.0101466	0.2727273	GO:0046636	GO:BP	negative regulation of alpha-beta T cell activation	16175	12273	GO:00466….
query_1	TRUE	0.0004767	9	887	5	0.0056370	0.5555556	GO:0001771	GO:BP	immunological synapse formation	16175	437	GO:00099….
query_1	TRUE	0.0004767	9	887	5	0.0056370	0.5555556	GO:0071639	GO:BP	positive regulation of monocyte chemotactic protein-1 production	16175	16816	GO:00327….
query_1	TRUE	0.0004767	9	887	5	0.0056370	0.5555556	GO:2000668	GO:BP	regulation of dendritic cell apoptotic process	16175	25943	GO:00970….
query_1	TRUE	0.0004767	9	887	5	0.0056370	0.5555556	GO:0097048	GO:BP	dendritic cell apoptotic process	16175	18461	GO:0071887
query_1	TRUE	0.0004767	26	887	8	0.0090192	0.3076923	GO:0090025	GO:BP	regulation of monocyte chemotaxis	16175	17959	GO:00025….
query_1	TRUE	0.0004767	9	887	5	0.0056370	0.5555556	GO:0002604	GO:BP	regulation of dendritic cell antigen processing and presentation	16175	1125	GO:00024….
query_1	TRUE	0.0004767	9	887	5	0.0056370	0.5555556	GO:0002765	GO:BP	immune response-inhibiting signal transduction	16175	1276	GO:0002764
query_1	TRUE	0.0004767	9	887	5	0.0056370	0.5555556	GO:0070383	GO:BP	DNA cytosine deamination	16175	16090	GO:0045006
query_1	TRUE	0.0004767	9	887	5	0.0056370	0.5555556	GO:2000508	GO:BP	regulation of dendritic cell chemotaxis	16175	25811	GO:00024….
query_1	TRUE	0.0005044	708	887	64	0.0721533	0.0903955	GO:0030029	GO:BP	actin filament-based process	16175	6653	GO:0009987
query_1	TRUE	0.0005073	14	887	6	0.0067644	0.4285714	GO:0050862	GO:BP	positive regulation of T cell receptor signaling pathway	16175	13310	GO:00508….
query_1	TRUE	0.0005073	14	887	6	0.0067644	0.4285714	GO:0002283	GO:BP	neutrophil activation involved in immune response	16175	815	GO:00022….
query_1	TRUE	0.0005097	41	887	10	0.0112740	0.2439024	GO:0009620	GO:BP	response to fungus	16175	3544	GO:0051707
query_1	TRUE	0.0005097	41	887	10	0.0112740	0.2439024	GO:0030225	GO:BP	macrophage differentiation	16175	6733	GO:00025….
query_1	TRUE	0.0005423	182	887	24	0.0270575	0.1318681	GO:0051651	GO:BP	maintenance of location in cell	16175	13864	GO:00099….
query_1	TRUE	0.0005497	20	887	7	0.0078918	0.3500000	GO:0002719	GO:BP	negative regulation of cytokine production involved in immune response	16175	1237	GO:00018….
query_1	TRUE	0.0005497	20	887	7	0.0078918	0.3500000	GO:0045591	GO:BP	positive regulation of regulatory T cell differentiation	16175	11442	GO:00450….
query_1	TRUE	0.0005497	20	887	7	0.0078918	0.3500000	GO:0019885	GO:BP	antigen processing and presentation of endogenous peptide antigen via MHC class I	16175	6063	GO:00024….
query_1	TRUE	0.0005497	20	887	7	0.0078918	0.3500000	GO:0002828	GO:BP	regulation of type 2 immune response	16175	1338	GO:00420….
query_1	TRUE	0.0005633	1260	887	101	0.1138670	0.0801587	GO:0009888	GO:BP	tissue development	16175	3748	GO:0048856
query_1	TRUE	0.0005661	96	887	16	0.0180383	0.1666667	GO:0007200	GO:BP	phospholipase C-activating G protein-coupled receptor signaling pathway	16175	2758	GO:0007186
query_1	TRUE	0.0005754	242	887	29	0.0326945	0.1198347	GO:0019058	GO:BP	viral life cycle	16175	5555	GO:0016032
query_1	TRUE	0.0005912	34	887	9	0.0101466	0.2647059	GO:0044546	GO:BP	NLRP3 inflammasome complex assembly	16175	11065	GO:0140632
query_1	TRUE	0.0005912	34	887	9	0.0101466	0.2647059	GO:0050798	GO:BP	activated T cell proliferation	16175	13265	GO:0042098
query_1	TRUE	0.0005977	50	887	11	0.0124014	0.2200000	GO:0010543	GO:BP	regulation of platelet activation	16175	4202	GO:00301….
query_1	TRUE	0.0006020	77	887	14	0.0157835	0.1818182	GO:0052548	GO:BP	regulation of endopeptidase activity	16175	14134	GO:0052547
query_1	TRUE	0.0006242	27	887	8	0.0090192	0.2962963	GO:0043372	GO:BP	positive regulation of CD4-positive, alpha-beta T cell differentiation	16175	10649	GO:00433….
query_1	TRUE	0.0006350	1249	887	100	0.1127396	0.0800641	GO:0042592	GO:BP	homeostatic process	16175	10252	GO:0008150
query_1	TRUE	0.0006650	208	887	26	0.0293123	0.1250000	GO:0051091	GO:BP	positive regulation of DNA-binding transcription factor activity	16175	13486	GO:00440….
query_1	TRUE	0.0006650	118	887	18	0.0202931	0.1525424	GO:0055001	GO:BP	muscle cell development	16175	14190	GO:00426….
query_1	TRUE	0.0007228	632	887	58	0.0653890	0.0917722	GO:0031401	GO:BP	positive regulation of protein modification process	16175	7157	GO:00313….
query_1	TRUE	0.0007325	1132	887	92	0.1037204	0.0812721	GO:0016310	GO:BP	phosphorylation	16175	5198	GO:0006796
query_1	TRUE	0.0007355	69	887	13	0.0146561	0.1884058	GO:0141060	GO:BP	disruption of anatomical structure in another organism	16175	19996	GO:0044419
query_1	TRUE	0.0007430	258	887	30	0.0338219	0.1162791	GO:0033674	GO:BP	positive regulation of kinase activity	16175	8346	GO:00423….
query_1	TRUE	0.0007438	163	887	22	0.0248027	0.1349693	GO:0043270	GO:BP	positive regulation of monoatomic ion transport	16175	10594	GO:00068….
query_1	TRUE	0.0007438	35	887	9	0.0101466	0.2571429	GO:0045581	GO:BP	negative regulation of T cell differentiation	16175	11432	GO:00302….
query_1	TRUE	0.0007441	60	887	12	0.0135287	0.2000000	GO:0141061	GO:BP	disruption of cell in another organism	16175	19997	GO:0141060
query_1	TRUE	0.0007441	60	887	12	0.0135287	0.2000000	GO:0031640	GO:BP	killing of cells of another organism	16175	7250	GO:00019….
query_1	TRUE	0.0007537	246	887	29	0.0326945	0.1178862	GO:0055074	GO:BP	calcium ion homeostasis	16175	14230	GO:00550….
query_1	TRUE	0.0007682	15	887	6	0.0067644	0.4000000	GO:0002716	GO:BP	negative regulation of natural killer cell mediated immunity	16175	1234	GO:00022….
query_1	TRUE	0.0007682	15	887	6	0.0067644	0.4000000	GO:0045869	GO:BP	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	16175	11677	GO:00396….
query_1	TRUE	0.0007682	15	887	6	0.0067644	0.4000000	GO:0045953	GO:BP	negative regulation of natural killer cell mediated cytotoxicity	16175	11745	GO:00019….
query_1	TRUE	0.0007682	15	887	6	0.0067644	0.4000000	GO:0021602	GO:BP	cranial nerve morphogenesis	16175	6185	GO:00096….
query_1	TRUE	0.0007682	15	887	6	0.0067644	0.4000000	GO:0032693	GO:BP	negative regulation of interleukin-10 production	16175	7739	GO:00018….
query_1	TRUE	0.0008101	28	887	8	0.0090192	0.2857143	GO:2000107	GO:BP	negative regulation of leukocyte apoptotic process	16175	25458	GO:00430….
query_1	TRUE	0.0008595	10	887	5	0.0056370	0.5000000	GO:0043320	GO:BP	natural killer cell degranulation	16175	10628	GO:00023….
query_1	TRUE	0.0008595	10	887	5	0.0056370	0.5000000	GO:2000425	GO:BP	regulation of apoptotic cell clearance	16175	25740	GO:00432….
query_1	TRUE	0.0008610	110	887	17	0.0191657	0.1545455	GO:0032606	GO:BP	type I interferon production	16175	7654	GO:0001816
query_1	TRUE	0.0008610	110	887	17	0.0191657	0.1545455	GO:0032479	GO:BP	regulation of type I interferon production	16175	7590	GO:00018….
query_1	TRUE	0.0008880	884	887	75	0.0845547	0.0848416	GO:0010629	GO:BP	negative regulation of gene expression	16175	4275	GO:00104….
query_1	TRUE	0.0009187	44	887	10	0.0112740	0.2272727	GO:2000351	GO:BP	regulation of endothelial cell apoptotic process	16175	25670	GO:00429….
query_1	TRUE	0.0009193	610	887	56	0.0631342	0.0918033	GO:0043066	GO:BP	negative regulation of apoptotic process	16175	10512	GO:00069….
query_1	TRUE	0.0009205	36	887	9	0.0101466	0.2500000	GO:0141085	GO:BP	regulation of inflammasome-mediated signaling pathway	16175	20016	GO:00395….
query_1	TRUE	0.0009654	583	887	54	0.0608794	0.0926244	GO:0032940	GO:BP	secretion by cell	16175	7926	GO:00469….
query_1	TRUE	0.0009670	71	887	13	0.0146561	0.1830986	GO:0002377	GO:BP	immunoglobulin production	16175	907	GO:0002440
query_1	TRUE	0.0009694	1829	887	136	0.1533258	0.0743576	GO:0009653	GO:BP	anatomical structure morphogenesis	16175	3571	GO:00325….
query_1	TRUE	0.0010345	22	887	7	0.0078918	0.3181818	GO:0032673	GO:BP	regulation of interleukin-4 production	16175	7719	GO:00018….
query_1	TRUE	0.0010345	22	887	7	0.0078918	0.3181818	GO:0032633	GO:BP	interleukin-4 production	16175	7680	GO:0001816
query_1	TRUE	0.0010345	22	887	7	0.0078918	0.3181818	GO:0034121	GO:BP	regulation of toll-like receptor signaling pathway	16175	8429	GO:00022….
query_1	TRUE	0.0010379	6	887	4	0.0045096	0.6666667	GO:0035744	GO:BP	T-helper 1 cell cytokine production	16175	9209	GO:00357….
query_1	TRUE	0.0010379	6	887	4	0.0045096	0.6666667	GO:2000554	GO:BP	regulation of T-helper 1 cell cytokine production	16175	25855	GO:00027….
query_1	TRUE	0.0010379	29	887	8	0.0090192	0.2758621	GO:0046640	GO:BP	regulation of alpha-beta T cell proliferation	16175	12277	GO:00421….
query_1	TRUE	0.0010379	6	887	4	0.0045096	0.6666667	GO:0099046	GO:BP	clearance of foreign intracellular nucleic acids	16175	19019	GO:0140546
query_1	TRUE	0.0010379	6	887	4	0.0045096	0.6666667	GO:0050859	GO:BP	negative regulation of B cell receptor signaling pathway	16175	13307	GO:00508….
query_1	TRUE	0.0010379	6	887	4	0.0045096	0.6666667	GO:0140970	GO:BP	AIM2 inflammasome complex assembly	16175	19954	GO:0065003
query_1	TRUE	0.0010379	6	887	4	0.0045096	0.6666667	GO:2000556	GO:BP	positive regulation of T-helper 1 cell cytokine production	16175	25857	GO:00027….
query_1	TRUE	0.0010379	6	887	4	0.0045096	0.6666667	GO:0002583	GO:BP	regulation of antigen processing and presentation of peptide antigen	16175	1104	GO:00025….
query_1	TRUE	0.0010379	6	887	4	0.0045096	0.6666667	GO:0044355	GO:BP	clearance of foreign intracellular DNA	16175	10971	GO:0099046
query_1	TRUE	0.0010379	6	887	4	0.0045096	0.6666667	GO:0031622	GO:BP	positive regulation of fever generation	16175	7239	GO:00016….
query_1	TRUE	0.0010379	6	887	4	0.0045096	0.6666667	GO:0033004	GO:BP	negative regulation of mast cell activation	16175	7973	GO:00026….
query_1	TRUE	0.0010379	6	887	4	0.0045096	0.6666667	GO:0034136	GO:BP	negative regulation of toll-like receptor 2 signaling pathway	16175	8444	GO:00026….
query_1	TRUE	0.0010379	6	887	4	0.0045096	0.6666667	GO:0002606	GO:BP	positive regulation of dendritic cell antigen processing and presentation	16175	1127	GO:00024….
query_1	TRUE	0.0010379	6	887	4	0.0045096	0.6666667	GO:0002445	GO:BP	type II hypersensitivity	16175	968	GO:00024….
query_1	TRUE	0.0010379	6	887	4	0.0045096	0.6666667	GO:0001788	GO:BP	antibody-dependent cellular cytotoxicity	16175	450	GO:00017….
query_1	TRUE	0.0010379	6	887	4	0.0045096	0.6666667	GO:0001794	GO:BP	type IIa hypersensitivity	16175	451	GO:0002445
query_1	TRUE	0.0010404	112	887	17	0.0191657	0.1517857	GO:0061041	GO:BP	regulation of wound healing	16175	15157	GO:00420….
query_1	TRUE	0.0010455	156	887	21	0.0236753	0.1346154	GO:0042063	GO:BP	gliogenesis	16175	9949	GO:0022008
query_1	TRUE	0.0010869	744	887	65	0.0732807	0.0873656	GO:0001932	GO:BP	regulation of protein phosphorylation	16175	546	GO:00064….
query_1	TRUE	0.0011130	16	887	6	0.0067644	0.3750000	GO:0034112	GO:BP	positive regulation of homotypic cell-cell adhesion	16175	8420	GO:00224….
query_1	TRUE	0.0011130	16	887	6	0.0067644	0.3750000	GO:0034134	GO:BP	toll-like receptor 2 signaling pathway	16175	8442	GO:0140895
query_1	TRUE	0.0011306	630	887	57	0.0642616	0.0904762	GO:0043069	GO:BP	negative regulation of programmed cell death	16175	10515	GO:00125….
query_1	TRUE	0.0011446	63	887	12	0.0135287	0.1904762	GO:0042509	GO:BP	regulation of tyrosine phosphorylation of STAT protein	16175	10226	GO:00072….
query_1	TRUE	0.0011516	54	887	11	0.0124014	0.2037037	GO:0042531	GO:BP	positive regulation of tyrosine phosphorylation of STAT protein	16175	10227	GO:00072….
query_1	TRUE	0.0012117	1120	887	90	0.1014656	0.0803571	GO:0023057	GO:BP	negative regulation of signaling	16175	6642	GO:00230….
query_1	TRUE	0.0012212	103	887	16	0.0180383	0.1553398	GO:0052547	GO:BP	regulation of peptidase activity	16175	14133	GO:00301….
query_1	TRUE	0.0013045	30	887	8	0.0090192	0.2666667	GO:0045429	GO:BP	positive regulation of nitric oxide biosynthetic process	16175	11373	GO:00068….
query_1	TRUE	0.0013138	577	887	53	0.0597520	0.0918544	GO:0043085	GO:BP	positive regulation of catalytic activity	16175	10518	GO:00440….
query_1	TRUE	0.0013283	64	887	12	0.0135287	0.1875000	GO:0019731	GO:BP	antibacterial humoral response	16175	6022	GO:00197….
query_1	TRUE	0.0013306	3	887	3	0.0033822	1.0000000	GO:0002408	GO:BP	myeloid dendritic cell chemotaxis	16175	932	GO:00024….
query_1	TRUE	0.0013306	3	887	3	0.0033822	1.0000000	GO:0070340	GO:BP	detection of bacterial lipopeptide	16175	16062	GO:00424….
query_1	TRUE	0.0013306	23	887	7	0.0078918	0.3043478	GO:0045954	GO:BP	positive regulation of natural killer cell mediated cytotoxicity	16175	11746	GO:00019….
query_1	TRUE	0.0013306	23	887	7	0.0078918	0.3043478	GO:0045671	GO:BP	negative regulation of osteoclast differentiation	16175	11522	GO:00027….
query_1	TRUE	0.0013306	3	887	3	0.0033822	1.0000000	GO:2000524	GO:BP	negative regulation of T cell costimulation	16175	25827	GO:00026….
query_1	TRUE	0.0013306	23	887	7	0.0078918	0.3043478	GO:0032691	GO:BP	negative regulation of interleukin-1 beta production	16175	7737	GO:00326….
query_1	TRUE	0.0013306	3	887	3	0.0033822	1.0000000	GO:0071613	GO:BP	granzyme B production	16175	16799	GO:0002440
query_1	TRUE	0.0013306	3	887	3	0.0033822	1.0000000	GO:0071661	GO:BP	regulation of granzyme B production	16175	16838	GO:00018….
query_1	TRUE	0.0013306	3	887	3	0.0033822	1.0000000	GO:0097026	GO:BP	dendritic cell dendrite assembly	16175	18450	GO:0120031
query_1	TRUE	0.0013306	23	887	7	0.0078918	0.3043478	GO:2000108	GO:BP	positive regulation of leukocyte apoptotic process	16175	25459	GO:00430….
query_1	TRUE	0.0013306	3	887	3	0.0033822	1.0000000	GO:0071663	GO:BP	positive regulation of granzyme B production	16175	16840	GO:00027….
query_1	TRUE	0.0013306	3	887	3	0.0033822	1.0000000	GO:0150064	GO:BP	vertebrate eye-specific patterning	16175	20120	GO:00030….
query_1	TRUE	0.0013306	3	887	3	0.0033822	1.0000000	GO:0002322	GO:BP	B cell proliferation involved in immune response	16175	854	GO:00023….
query_1	TRUE	0.0013306	3	887	3	0.0033822	1.0000000	GO:2000547	GO:BP	regulation of dendritic cell dendrite assembly	16175	25848	GO:00970….
query_1	TRUE	0.0013306	3	887	3	0.0033822	1.0000000	GO:0002277	GO:BP	myeloid dendritic cell activation involved in immune response	16175	809	GO:00017….
query_1	TRUE	0.0013306	3	887	3	0.0033822	1.0000000	GO:0043305	GO:BP	negative regulation of mast cell degranulation	16175	10613	GO:00028….
query_1	TRUE	0.0013423	38	887	9	0.0101466	0.2368421	GO:0002347	GO:BP	response to tumor cell	16175	879	GO:0009607
query_1	TRUE	0.0013678	11	887	5	0.0056370	0.4545455	GO:0002679	GO:BP	respiratory burst involved in defense response	16175	1197	GO:00022….
query_1	TRUE	0.0013678	11	887	5	0.0056370	0.4545455	GO:0070234	GO:BP	positive regulation of T cell apoptotic process	16175	16004	GO:00702….
query_1	TRUE	0.0013678	11	887	5	0.0056370	0.4545455	GO:0030852	GO:BP	regulation of granulocyte differentiation	16175	6935	GO:00027….
query_1	TRUE	0.0013678	11	887	5	0.0056370	0.4545455	GO:0035723	GO:BP	interleukin-15-mediated signaling pathway	16175	9193	GO:00192….
query_1	TRUE	0.0013678	11	887	5	0.0056370	0.4545455	GO:0001768	GO:BP	establishment of T cell polarity	16175	434	GO:00017….
query_1	TRUE	0.0013678	11	887	5	0.0056370	0.4545455	GO:0001782	GO:BP	B cell homeostasis	16175	447	GO:0002260
query_1	TRUE	0.0013678	11	887	5	0.0056370	0.4545455	GO:0034135	GO:BP	regulation of toll-like receptor 2 signaling pathway	16175	8443	GO:00341….
query_1	TRUE	0.0013678	11	887	5	0.0056370	0.4545455	GO:0071350	GO:BP	cellular response to interleukin-15	16175	16602	GO:00706….
query_1	TRUE	0.0013678	11	887	5	0.0056370	0.4545455	GO:0070672	GO:BP	response to interleukin-15	16175	16253	GO:0034097
query_1	TRUE	0.0013678	11	887	5	0.0056370	0.4545455	GO:0046007	GO:BP	negative regulation of activated T cell proliferation	16175	11798	GO:00421….
query_1	TRUE	0.0013743	74	887	13	0.0146561	0.1756757	GO:0050848	GO:BP	regulation of calcium-mediated signaling	16175	13296	GO:00197….
query_1	TRUE	0.0013743	94	887	15	0.0169109	0.1595745	GO:1903531	GO:BP	negative regulation of secretion by cell	16175	23081	GO:00329….
query_1	TRUE	0.0014169	400	887	40	0.0450958	0.1000000	GO:0001525	GO:BP	angiogenesis	16175	330	GO:00485….
query_1	TRUE	0.0014934	184	887	23	0.0259301	0.1250000	GO:0051259	GO:BP	protein complex oligomerization	16175	13606	GO:0065003
query_1	TRUE	0.0015473	17	887	6	0.0067644	0.3529412	GO:0150146	GO:BP	cell junction disassembly	16175	20166	GO:00224….
query_1	TRUE	0.0015473	17	887	6	0.0067644	0.3529412	GO:0032717	GO:BP	negative regulation of interleukin-8 production	16175	7762	GO:00018….
query_1	TRUE	0.0015473	17	887	6	0.0067644	0.3529412	GO:0055003	GO:BP	cardiac myofibril assembly	16175	14192	GO:00302….
query_1	TRUE	0.0015473	17	887	6	0.0067644	0.3529412	GO:0071353	GO:BP	cellular response to interleukin-4	16175	16605	GO:00706….
query_1	TRUE	0.0015717	1115	887	89	0.1003382	0.0798206	GO:0010648	GO:BP	negative regulation of cell communication	16175	4294	GO:00071….
query_1	TRUE	0.0015757	221	887	26	0.0293123	0.1176471	GO:0006898	GO:BP	receptor-mediated endocytosis	16175	2552	GO:0006897
query_1	TRUE	0.0015821	31	887	8	0.0090192	0.2580645	GO:0002230	GO:BP	positive regulation of defense response to virus by host	16175	763	GO:0050691
query_1	TRUE	0.0015821	31	887	8	0.0090192	0.2580645	GO:1904407	GO:BP	positive regulation of nitric oxide metabolic process	16175	23791	GO:00098….
query_1	TRUE	0.0015821	31	887	8	0.0090192	0.2580645	GO:0070231	GO:BP	T cell apoptotic process	16175	16001	GO:0070227
query_1	TRUE	0.0017168	96	887	15	0.0169109	0.1562500	GO:0010927	GO:BP	cellular component assembly involved in morphogenesis	16175	4511	GO:00226….
query_1	TRUE	0.0017168	96	887	15	0.0169109	0.1562500	GO:0032989	GO:BP	cellular anatomical entity morphogenesis	16175	7969	GO:0016043
query_1	TRUE	0.0017269	24	887	7	0.0078918	0.2916667	GO:0030851	GO:BP	granulocyte differentiation	16175	6934	GO:0002573
query_1	TRUE	0.0018804	236	887	27	0.0304397	0.1144068	GO:0050678	GO:BP	regulation of epithelial cell proliferation	16175	13212	GO:00421….
query_1	TRUE	0.0018804	1045	887	84	0.0947012	0.0803828	GO:0006468	GO:BP	protein phosphorylation	16175	2207	GO:00163….
query_1	TRUE	0.0018914	274	887	30	0.0338219	0.1094891	GO:0051235	GO:BP	maintenance of location	16175	13585	GO:0051179
query_1	TRUE	0.0019613	434	887	42	0.0473506	0.0967742	GO:0045596	GO:BP	negative regulation of cell differentiation	16175	11447	GO:00301….
query_1	TRUE	0.0019855	32	887	8	0.0090192	0.2500000	GO:1904646	GO:BP	cellular response to amyloid-beta	16175	23986	GO:19016….
query_1	TRUE	0.0019855	32	887	8	0.0090192	0.2500000	GO:1905521	GO:BP	regulation of macrophage migration	16175	24697	GO:00716….
query_1	TRUE	0.0019918	87	887	14	0.0157835	0.1609195	GO:1903305	GO:BP	regulation of regulated secretory pathway	16175	22892	GO:00171….
query_1	TRUE	0.0020208	504	887	47	0.0529876	0.0932540	GO:0001944	GO:BP	vasculature development	16175	555	GO:00487….
query_1	TRUE	0.0020208	119	887	17	0.0191657	0.1428571	GO:0019079	GO:BP	viral genome replication	16175	5569	GO:00160….
query_1	TRUE	0.0020524	250	887	28	0.0315671	0.1120000	GO:0042692	GO:BP	muscle cell differentiation	16175	10302	GO:00301….
query_1	TRUE	0.0020577	7	887	4	0.0045096	0.5714286	GO:0030240	GO:BP	skeletal muscle thin filament assembly	16175	6737	GO:00070….
query_1	TRUE	0.0020577	7	887	4	0.0045096	0.5714286	GO:0002729	GO:BP	positive regulation of natural killer cell cytokine production	16175	1247	GO:00023….
query_1	TRUE	0.0020577	7	887	4	0.0045096	0.5714286	GO:0071221	GO:BP	cellular response to bacterial lipopeptide	16175	16483	GO:00703….
query_1	TRUE	0.0020577	7	887	4	0.0045096	0.5714286	GO:0071220	GO:BP	cellular response to bacterial lipoprotein	16175	16482	GO:00324….
query_1	TRUE	0.0020577	49	887	10	0.0112740	0.2040816	GO:0072577	GO:BP	endothelial cell apoptotic process	16175	17450	GO:0006915
query_1	TRUE	0.0020577	7	887	4	0.0045096	0.5714286	GO:0001660	GO:BP	fever generation	16175	374	GO:00069….
query_1	TRUE	0.0020577	7	887	4	0.0045096	0.5714286	GO:0021612	GO:BP	facial nerve structural organization	16175	6195	GO:00216….
query_1	TRUE	0.0020577	422	887	41	0.0462232	0.0971564	GO:0030003	GO:BP	intracellular monoatomic cation homeostasis	16175	6648	GO:00068….
query_1	TRUE	0.0020577	7	887	4	0.0045096	0.5714286	GO:0002727	GO:BP	regulation of natural killer cell cytokine production	16175	1245	GO:00023….
query_1	TRUE	0.0020577	49	887	10	0.0112740	0.2040816	GO:0046456	GO:BP	icosanoid biosynthetic process	16175	12164	GO:00066….
query_1	TRUE	0.0020577	7	887	4	0.0045096	0.5714286	GO:0002291	GO:BP	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	16175	823	GO:0002286
query_1	TRUE	0.0020577	341	887	35	0.0394589	0.1026393	GO:0043269	GO:BP	regulation of monoatomic ion transport	16175	10593	GO:00068….
query_1	TRUE	0.0020577	7	887	4	0.0045096	0.5714286	GO:0031620	GO:BP	regulation of fever generation	16175	7237	GO:00016….
query_1	TRUE	0.0020577	7	887	4	0.0045096	0.5714286	GO:0031392	GO:BP	regulation of prostaglandin biosynthetic process	16175	7149	GO:00015….
query_1	TRUE	0.0020577	7	887	4	0.0045096	0.5714286	GO:0021610	GO:BP	facial nerve morphogenesis	16175	6193	GO:00215….
query_1	TRUE	0.0020577	7	887	4	0.0045096	0.5714286	GO:2001280	GO:BP	positive regulation of unsaturated fatty acid biosynthetic process	16175	26457	GO:00066….
query_1	TRUE	0.0020577	7	887	4	0.0045096	0.5714286	GO:0002370	GO:BP	natural killer cell cytokine production	16175	902	GO:00022….
query_1	TRUE	0.0020577	7	887	4	0.0045096	0.5714286	GO:0031666	GO:BP	positive regulation of lipopolysaccharide-mediated signaling pathway	16175	7270	GO:00028….
query_1	TRUE	0.0020577	7	887	4	0.0045096	0.5714286	GO:0021561	GO:BP	facial nerve development	16175	6145	GO:00215….
query_1	TRUE	0.0020577	7	887	4	0.0045096	0.5714286	GO:0070339	GO:BP	response to bacterial lipopeptide	16175	16061	GO:0032493
query_1	TRUE	0.0020577	7	887	4	0.0045096	0.5714286	GO:1904124	GO:BP	microglial cell migration	16175	23546	GO:00083….
query_1	TRUE	0.0020577	7	887	4	0.0045096	0.5714286	GO:1904139	GO:BP	regulation of microglial cell migration	16175	23561	GO:19039….
query_1	TRUE	0.0020577	7	887	4	0.0045096	0.5714286	GO:0031652	GO:BP	positive regulation of heat generation	16175	7262	GO:00316….
query_1	TRUE	0.0020676	12	887	5	0.0056370	0.4166667	GO:0034695	GO:BP	response to prostaglandin E	16175	8717	GO:00346….
query_1	TRUE	0.0020676	12	887	5	0.0056370	0.4166667	GO:0046851	GO:BP	negative regulation of bone remodeling	16175	12403	GO:00341….
query_1	TRUE	0.0020676	12	887	5	0.0056370	0.4166667	GO:0060099	GO:BP	regulation of phagocytosis, engulfment	16175	14355	GO:00069….
query_1	TRUE	0.0020676	18	887	6	0.0067644	0.3333333	GO:0045091	GO:BP	regulation of single stranded viral RNA replication via double stranded DNA intermediate	16175	11273	GO:00396….
query_1	TRUE	0.0020676	12	887	5	0.0056370	0.4166667	GO:0016554	GO:BP	cytidine to uridine editing	16175	5245	GO:0016553
query_1	TRUE	0.0020676	12	887	5	0.0056370	0.4166667	GO:0001767	GO:BP	establishment of lymphocyte polarity	16175	433	GO:00300….
query_1	TRUE	0.0020676	12	887	5	0.0056370	0.4166667	GO:0071605	GO:BP	monocyte chemotactic protein-1 production	16175	16791	GO:0032602
query_1	TRUE	0.0020676	18	887	6	0.0067644	0.3333333	GO:0070670	GO:BP	response to interleukin-4	16175	16251	GO:0034097
query_1	TRUE	0.0020676	12	887	5	0.0056370	0.4166667	GO:0021559	GO:BP	trigeminal nerve development	16175	6143	GO:0021545
query_1	TRUE	0.0020676	18	887	6	0.0067644	0.3333333	GO:0046641	GO:BP	positive regulation of alpha-beta T cell proliferation	16175	12278	GO:00421….
query_1	TRUE	0.0020676	12	887	5	0.0056370	0.4166667	GO:0071637	GO:BP	regulation of monocyte chemotactic protein-1 production	16175	16814	GO:00326….
query_1	TRUE	0.0020676	18	887	6	0.0067644	0.3333333	GO:0033630	GO:BP	positive regulation of cell adhesion mediated by integrin	16175	8331	GO:00336….
query_1	TRUE	0.0020676	12	887	5	0.0056370	0.4166667	GO:1905153	GO:BP	regulation of membrane invagination	16175	24401	GO:00103….
query_1	TRUE	0.0021057	131	887	18	0.0202931	0.1374046	GO:0043409	GO:BP	negative regulation of MAPK cascade	16175	10677	GO:00001….
query_1	TRUE	0.0022615	41	887	9	0.0101466	0.2195122	GO:1904645	GO:BP	response to amyloid-beta	16175	23985	GO:19016….
query_1	TRUE	0.0023103	132	887	18	0.0202931	0.1363636	GO:1903034	GO:BP	regulation of response to wounding	16175	22714	GO:00096….
query_1	TRUE	0.0023554	33	887	8	0.0090192	0.2424242	GO:0046006	GO:BP	regulation of activated T cell proliferation	16175	11797	GO:00421….
query_1	TRUE	0.0023554	33	887	8	0.0090192	0.2424242	GO:1900225	GO:BP	regulation of NLRP3 inflammasome complex assembly	16175	20497	GO:00432….
query_1	TRUE	0.0023554	33	887	8	0.0090192	0.2424242	GO:0034110	GO:BP	regulation of homotypic cell-cell adhesion	16175	8418	GO:00224….
query_1	TRUE	0.0023713	1070	887	85	0.0958286	0.0794393	GO:0009968	GO:BP	negative regulation of signal transduction	16175	3806	GO:00071….
query_1	TRUE	0.0023990	412	887	40	0.0450958	0.0970874	GO:0045859	GO:BP	regulation of protein kinase activity	16175	11671	GO:00019….
query_1	TRUE	0.0024308	426	887	41	0.0462232	0.0962441	GO:0006873	GO:BP	intracellular monoatomic ion homeostasis	16175	2531	GO:00508….
query_1	TRUE	0.0024581	79	887	13	0.0146561	0.1645570	GO:0045639	GO:BP	positive regulation of myeloid cell differentiation	16175	11490	GO:00300….
query_1	TRUE	0.0024598	241	887	27	0.0304397	0.1120332	GO:0045860	GO:BP	positive regulation of protein kinase activity	16175	11672	GO:00019….
query_1	TRUE	0.0026809	90	887	14	0.0157835	0.1555556	GO:2001235	GO:BP	positive regulation of apoptotic signaling pathway	16175	26424	GO:00099….
query_1	TRUE	0.0027033	42	887	9	0.0101466	0.2142857	GO:1905517	GO:BP	macrophage migration	16175	24693	GO:00716….
query_1	TRUE	0.0027472	193	887	23	0.0259301	0.1191710	GO:0098742	GO:BP	cell-cell adhesion via plasma-membrane adhesion molecules	16175	18867	GO:0098609
query_1	TRUE	0.0027607	26	887	7	0.0078918	0.2692308	GO:0008347	GO:BP	glial cell migration	16175	3172	GO:00164….
query_1	TRUE	0.0027704	744	887	63	0.0710259	0.0846774	GO:0072359	GO:BP	circulatory system development	16175	17370	GO:0048731
query_1	TRUE	0.0027920	101	887	15	0.0169109	0.1485149	GO:0007229	GO:BP	integrin-mediated signaling pathway	16175	2779	GO:0007166
query_1	TRUE	0.0028145	19	887	6	0.0067644	0.3157895	GO:0043304	GO:BP	regulation of mast cell degranulation	16175	10612	GO:00028….
query_1	TRUE	0.0028145	19	887	6	0.0067644	0.3157895	GO:0039692	GO:BP	single stranded viral RNA replication via double stranded DNA intermediate	16175	9869	GO:0039694
query_1	TRUE	0.0028808	34	887	8	0.0090192	0.2352941	GO:0042554	GO:BP	superoxide anion generation	16175	10244	GO:0006801
query_1	TRUE	0.0028808	34	887	8	0.0090192	0.2352941	GO:2001238	GO:BP	positive regulation of extrinsic apoptotic signaling pathway	16175	26427	GO:00971….
query_1	TRUE	0.0029665	170	887	21	0.0236753	0.1235294	GO:0097191	GO:BP	extrinsic apoptotic signaling pathway	16175	18535	GO:00071….
query_1	TRUE	0.0030736	124	887	17	0.0191657	0.1370968	GO:0043405	GO:BP	regulation of MAP kinase activity	16175	10673	GO:0071900
query_1	TRUE	0.0030847	102	887	15	0.0169109	0.1470588	GO:0008360	GO:BP	regulation of cell shape	16175	3179	GO:00226….
query_1	TRUE	0.0030940	13	887	5	0.0056370	0.3846154	GO:0034144	GO:BP	negative regulation of toll-like receptor 4 signaling pathway	16175	8452	GO:00026….
query_1	TRUE	0.0030940	13	887	5	0.0056370	0.3846154	GO:0071800	GO:BP	podosome assembly	16175	16914	GO:00650….
query_1	TRUE	0.0030940	13	887	5	0.0056370	0.3846154	GO:0070230	GO:BP	positive regulation of lymphocyte apoptotic process	16175	16000	GO:00702….
query_1	TRUE	0.0030940	13	887	5	0.0056370	0.3846154	GO:0031643	GO:BP	positive regulation of myelination	16175	7253	GO:00316….
query_1	TRUE	0.0030940	13	887	5	0.0056370	0.3846154	GO:0045006	GO:BP	DNA deamination	16175	11224	GO:0006304
query_1	TRUE	0.0030940	13	887	5	0.0056370	0.3846154	GO:0023035	GO:BP	CD40 signaling pathway	16175	6637	GO:0007166
query_1	TRUE	0.0031211	71	887	12	0.0135287	0.1690141	GO:0045638	GO:BP	negative regulation of myeloid cell differentiation	16175	11489	GO:00300….
query_1	TRUE	0.0031969	52	887	10	0.0112740	0.1923077	GO:0007157	GO:BP	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules	16175	2721	GO:0098742
query_1	TRUE	0.0032188	646	887	56	0.0631342	0.0866873	GO:0140352	GO:BP	export from cell	16175	19748	GO:00068….
query_1	TRUE	0.0032884	92	887	14	0.0157835	0.1521739	GO:0016525	GO:BP	negative regulation of angiogenesis	16175	5237	GO:00015….
query_1	TRUE	0.0033649	272	887	29	0.0326945	0.1066176	GO:0050673	GO:BP	epithelial cell proliferation	16175	13207	GO:0008283
query_1	TRUE	0.0033815	575	887	51	0.0574972	0.0886957	GO:0044092	GO:BP	negative regulation of molecular function	16175	10914	GO:0065009
query_1	TRUE	0.0034123	172	887	21	0.0236753	0.1220930	GO:0034764	GO:BP	positive regulation of transmembrane transport	16175	8733	GO:00347….
query_1	TRUE	0.0034518	27	887	7	0.0078918	0.2592593	GO:0021545	GO:BP	cranial nerve development	16175	6129	GO:0021675
query_1	TRUE	0.0034518	27	887	7	0.0078918	0.2592593	GO:0032692	GO:BP	negative regulation of interleukin-1 production	16175	7738	GO:00018….
query_1	TRUE	0.0035319	407	887	39	0.0439684	0.0958231	GO:0098771	GO:BP	inorganic ion homeostasis	16175	18886	GO:0048878
query_1	TRUE	0.0036314	8	887	4	0.0045096	0.5000000	GO:0002578	GO:BP	negative regulation of antigen processing and presentation	16175	1099	GO:00025….
query_1	TRUE	0.0036314	8	887	4	0.0045096	0.5000000	GO:0021604	GO:BP	cranial nerve structural organization	16175	6187	GO:00216….
query_1	TRUE	0.0036314	93	887	14	0.0157835	0.1505376	GO:2000181	GO:BP	negative regulation of blood vessel morphogenesis	16175	25513	GO:00226….
query_1	TRUE	0.0036314	8	887	4	0.0045096	0.5000000	GO:0031650	GO:BP	regulation of heat generation	16175	7260	GO:00316….
query_1	TRUE	0.0036314	8	887	4	0.0045096	0.5000000	GO:1903977	GO:BP	positive regulation of glial cell migration	16175	23434	GO:00083….
query_1	TRUE	0.0036314	8	887	4	0.0045096	0.5000000	GO:0031649	GO:BP	heat generation	16175	7259	GO:0001659
query_1	TRUE	0.0036314	8	887	4	0.0045096	0.5000000	GO:0045059	GO:BP	positive thymic T cell selection	16175	11257	GO:00433….
query_1	TRUE	0.0036314	8	887	4	0.0045096	0.5000000	GO:2000427	GO:BP	positive regulation of apoptotic cell clearance	16175	25742	GO:00432….
query_1	TRUE	0.0036314	8	887	4	0.0045096	0.5000000	GO:2000510	GO:BP	positive regulation of dendritic cell chemotaxis	16175	25813	GO:00024….
query_1	TRUE	0.0036314	8	887	4	0.0045096	0.5000000	GO:0097527	GO:BP	necroptotic signaling pathway	16175	18687	GO:00071….
query_1	TRUE	0.0036314	8	887	4	0.0045096	0.5000000	GO:0032493	GO:BP	response to bacterial lipoprotein	16175	7604	GO:0002237
query_1	TRUE	0.0036314	8	887	4	0.0045096	0.5000000	GO:0043376	GO:BP	regulation of CD8-positive, alpha-beta T cell differentiation	16175	10653	GO:00433….
query_1	TRUE	0.0036314	8	887	4	0.0045096	0.5000000	GO:0002767	GO:BP	immune response-inhibiting cell surface receptor signaling pathway	16175	1278	GO:00027….
query_1	TRUE	0.0036314	173	887	21	0.0236753	0.1213873	GO:0031334	GO:BP	positive regulation of protein-containing complex assembly	16175	7125	GO:00432….
query_1	TRUE	0.0036500	53	887	10	0.0112740	0.1886792	GO:0034142	GO:BP	toll-like receptor 4 signaling pathway	16175	8450	GO:0140895
query_1	TRUE	0.0036631	104	887	15	0.0169109	0.1442308	GO:0009612	GO:BP	response to mechanical stimulus	16175	3540	GO:00096….
query_1	TRUE	0.0036631	20	887	6	0.0067644	0.3000000	GO:0002675	GO:BP	positive regulation of acute inflammatory response	16175	1193	GO:00025….
query_1	TRUE	0.0036631	20	887	6	0.0067644	0.3000000	GO:0141087	GO:BP	positive regulation of inflammasome-mediated signaling pathway	16175	20018	GO:00622….
query_1	TRUE	0.0036891	44	887	9	0.0101466	0.2045455	GO:0045428	GO:BP	regulation of nitric oxide biosynthetic process	16175	11372	GO:00068….
query_1	TRUE	0.0038864	63	887	11	0.0124014	0.1746032	GO:0061045	GO:BP	negative regulation of wound healing	16175	15161	GO:00321….
query_1	TRUE	0.0039045	275	887	29	0.0326945	0.1054545	GO:2001233	GO:BP	regulation of apoptotic signaling pathway	16175	26422	GO:00099….
query_1	TRUE	0.0039780	94	887	14	0.0157835	0.1489362	GO:1901343	GO:BP	negative regulation of vasculature development	16175	21402	GO:00019….
query_1	TRUE	0.0039928	480	887	44	0.0496054	0.0916667	GO:0001568	GO:BP	blood vessel development	16175	353	GO:00019….
query_1	TRUE	0.0041418	36	887	8	0.0090192	0.2222222	GO:1900744	GO:BP	regulation of p38MAPK cascade	16175	20916	GO:00380….
query_1	TRUE	0.0042094	54	887	10	0.0112740	0.1851852	GO:0002312	GO:BP	B cell activation involved in immune response	16175	844	GO:00022….
query_1	TRUE	0.0042094	54	887	10	0.0112740	0.1851852	GO:0050688	GO:BP	regulation of defense response to virus	16175	13219	GO:00028….
query_1	TRUE	0.0042329	4	887	3	0.0033822	0.7500000	GO:0043615	GO:BP	astrocyte cell migration	16175	10806	GO:0008347
query_1	TRUE	0.0042329	4	887	3	0.0033822	0.7500000	GO:0042494	GO:BP	detection of bacterial lipoprotein	16175	10222	GO:00160….
query_1	TRUE	0.0042329	128	887	17	0.0191657	0.1328125	GO:0034767	GO:BP	positive regulation of monoatomic ion transmembrane transport	16175	8736	GO:00342….
query_1	TRUE	0.0042329	4	887	3	0.0033822	0.7500000	GO:1904151	GO:BP	positive regulation of microglial cell mediated cytotoxicity	16175	23572	GO:00019….
query_1	TRUE	0.0042329	4	887	3	0.0033822	0.7500000	GO:1904997	GO:BP	regulation of leukocyte adhesion to arterial endothelial cell	16175	24282	GO:00617….
query_1	TRUE	0.0042329	4	887	3	0.0033822	0.7500000	GO:0061044	GO:BP	negative regulation of vascular wound healing	16175	15160	GO:00165….
query_1	TRUE	0.0042329	28	887	7	0.0078918	0.2500000	GO:0034143	GO:BP	regulation of toll-like receptor 4 signaling pathway	16175	8451	GO:00341….
query_1	TRUE	0.0042329	4	887	3	0.0033822	0.7500000	GO:0002774	GO:BP	Fc receptor mediated inhibitory signaling pathway	16175	1285	GO:0002767
query_1	TRUE	0.0042329	4	887	3	0.0033822	0.7500000	GO:0002282	GO:BP	microglial cell activation involved in immune response	16175	814	GO:00017….
query_1	TRUE	0.0042329	4	887	3	0.0033822	0.7500000	GO:2000348	GO:BP	regulation of CD40 signaling pathway	16175	25667	GO:00099….
query_1	TRUE	0.0042329	4	887	3	0.0033822	0.7500000	GO:0034124	GO:BP	regulation of MyD88-dependent toll-like receptor signaling pathway	16175	8432	GO:00027….
query_1	TRUE	0.0042329	4	887	3	0.0033822	0.7500000	GO:0002666	GO:BP	positive regulation of T cell tolerance induction	16175	1184	GO:00025….
query_1	TRUE	0.0042818	45	887	9	0.0101466	0.2000000	GO:0002763	GO:BP	positive regulation of myeloid leukocyte differentiation	16175	1274	GO:00025….
query_1	TRUE	0.0042818	45	887	9	0.0101466	0.2000000	GO:0038066	GO:BP	p38MAPK cascade	16175	9683	GO:0000165
query_1	TRUE	0.0042818	45	887	9	0.0101466	0.2000000	GO:0002637	GO:BP	regulation of immunoglobulin production	16175	1158	GO:00023….
query_1	TRUE	0.0042997	14	887	5	0.0056370	0.3571429	GO:0034104	GO:BP	negative regulation of tissue remodeling	16175	8412	GO:00341….
query_1	TRUE	0.0042997	14	887	5	0.0056370	0.3571429	GO:0010935	GO:BP	regulation of macrophage cytokine production	16175	4519	GO:00027….
query_1	TRUE	0.0042997	14	887	5	0.0056370	0.3571429	GO:0010934	GO:BP	macrophage cytokine production	16175	4518	GO:0061082
query_1	TRUE	0.0042997	14	887	5	0.0056370	0.3571429	GO:0150079	GO:BP	negative regulation of neuroinflammatory response	16175	20131	GO:00507….
query_1	TRUE	0.0042997	14	887	5	0.0056370	0.3571429	GO:0072567	GO:BP	chemokine (C-X-C motif) ligand 2 production	16175	17445	GO:0032602
query_1	TRUE	0.0042997	14	887	5	0.0056370	0.3571429	GO:2000341	GO:BP	regulation of chemokine (C-X-C motif) ligand 2 production	16175	25660	GO:00326….
query_1	TRUE	0.0042997	14	887	5	0.0056370	0.3571429	GO:0002523	GO:BP	leukocyte migration involved in inflammatory response	16175	1045	GO:00069….
query_1	TRUE	0.0045199	512	887	46	0.0518602	0.0898438	GO:0051338	GO:BP	regulation of transferase activity	16175	13665	GO:0050790
query_1	TRUE	0.0046413	414	887	39	0.0439684	0.0942029	GO:0061061	GO:BP	muscle structure development	16175	15177	GO:0048856
query_1	TRUE	0.0046679	141	887	18	0.0202931	0.1276596	GO:0050679	GO:BP	positive regulation of epithelial cell proliferation	16175	13213	GO:00082….
query_1	TRUE	0.0046974	21	887	6	0.0067644	0.2857143	GO:2001056	GO:BP	positive regulation of cysteine-type endopeptidase activity	16175	26298	GO:00109….
query_1	TRUE	0.0046974	21	887	6	0.0067644	0.2857143	GO:1900016	GO:BP	negative regulation of cytokine production involved in inflammatory response	16175	20327	GO:00018….
query_1	TRUE	0.0046974	21	887	6	0.0067644	0.2857143	GO:0061082	GO:BP	myeloid leukocyte cytokine production	16175	15198	GO:0002367
query_1	TRUE	0.0048505	37	887	8	0.0090192	0.2162162	GO:0045453	GO:BP	bone resorption	16175	11383	GO:00018….
query_1	TRUE	0.0048505	37	887	8	0.0090192	0.2162162	GO:0043277	GO:BP	apoptotic cell clearance	16175	10598	GO:0006909
query_1	TRUE	0.0048505	748	887	62	0.0698985	0.0828877	GO:0006812	GO:BP	monoatomic cation transport	16175	2492	GO:0006811
query_1	TRUE	0.0049734	46	887	9	0.0101466	0.1956522	GO:0080164	GO:BP	regulation of nitric oxide metabolic process	16175	17838	GO:00192….
query_1	TRUE	0.0051480	29	887	7	0.0078918	0.2413793	GO:0002323	GO:BP	natural killer cell activation involved in immune response	16175	855	GO:00022….
query_1	TRUE	0.0054072	677	887	57	0.0642616	0.0841950	GO:0030001	GO:BP	metal ion transport	16175	6646	GO:0006812
query_1	TRUE	0.0055593	217	887	24	0.0270575	0.1105991	GO:0007188	GO:BP	adenylate cyclase-modulating G protein-coupled receptor signaling pathway	16175	2746	GO:0007186
query_1	TRUE	0.0055640	619	887	53	0.0597520	0.0856220	GO:1901698	GO:BP	response to nitrogen compound	16175	21651	GO:0042221
query_1	TRUE	0.0055640	66	887	11	0.0124014	0.1666667	GO:0032481	GO:BP	positive regulation of type I interferon production	16175	7592	GO:00018….
query_1	TRUE	0.0057201	447	887	41	0.0462232	0.0917226	GO:0048514	GO:BP	blood vessel morphogenesis	16175	12799	GO:00015….
query_1	TRUE	0.0057889	38	887	8	0.0090192	0.2105263	GO:0002686	GO:BP	negative regulation of leukocyte migration	16175	1204	GO:00026….
query_1	TRUE	0.0057889	38	887	8	0.0090192	0.2105263	GO:0033077	GO:BP	T cell differentiation in thymus	16175	8025	GO:0030217
query_1	TRUE	0.0057889	38	887	8	0.0090192	0.2105263	GO:0050832	GO:BP	defense response to fungus	16175	13290	GO:00096….
query_1	TRUE	0.0057928	47	887	9	0.0101466	0.1914894	GO:0046596	GO:BP	regulation of viral entry into host cell	16175	12246	GO:00467….
query_1	TRUE	0.0058218	9	887	4	0.0045096	0.4444444	GO:2001279	GO:BP	regulation of unsaturated fatty acid biosynthetic process	16175	26456	GO:00066….
query_1	TRUE	0.0058218	9	887	4	0.0045096	0.4444444	GO:0043307	GO:BP	eosinophil activation	16175	10615	GO:0036230
query_1	TRUE	0.0058218	9	887	4	0.0045096	0.4444444	GO:0014866	GO:BP	skeletal myofibril assembly	16175	4743	GO:0030239
query_1	TRUE	0.0058218	9	887	4	0.0045096	0.4444444	GO:0060267	GO:BP	positive regulation of respiratory burst	16175	14484	GO:00098….
query_1	TRUE	0.0058218	9	887	4	0.0045096	0.4444444	GO:0038110	GO:BP	interleukin-2-mediated signaling pathway	16175	9704	GO:00192….
query_1	TRUE	0.0058218	9	887	4	0.0045096	0.4444444	GO:0060907	GO:BP	positive regulation of macrophage cytokine production	16175	15037	GO:00109….
query_1	TRUE	0.0058218	9	887	4	0.0045096	0.4444444	GO:0032661	GO:BP	regulation of interleukin-18 production	16175	7707	GO:00018….
query_1	TRUE	0.0058218	9	887	4	0.0045096	0.4444444	GO:0071352	GO:BP	cellular response to interleukin-2	16175	16604	GO:00706….
query_1	TRUE	0.0058218	9	887	4	0.0045096	0.4444444	GO:0002725	GO:BP	negative regulation of T cell cytokine production	16175	1243	GO:00023….
query_1	TRUE	0.0058218	9	887	4	0.0045096	0.4444444	GO:0032621	GO:BP	interleukin-18 production	16175	7668	GO:0001816
query_1	TRUE	0.0059225	15	887	5	0.0056370	0.3333333	GO:0007252	GO:BP	I-kappaB phosphorylation	16175	2785	GO:00064….
query_1	TRUE	0.0059225	15	887	5	0.0056370	0.3333333	GO:0034694	GO:BP	response to prostaglandin	16175	8716	GO:00097….
query_1	TRUE	0.0059225	15	887	5	0.0056370	0.3333333	GO:1903978	GO:BP	regulation of microglial cell activation	16175	23435	GO:00017….
query_1	TRUE	0.0059225	15	887	5	0.0056370	0.3333333	GO:0002428	GO:BP	antigen processing and presentation of peptide antigen via MHC class Ib	16175	951	GO:00024….
query_1	TRUE	0.0059225	15	887	5	0.0056370	0.3333333	GO:0002476	GO:BP	antigen processing and presentation of endogenous peptide antigen via MHC class Ib	16175	999	GO:00024….
query_1	TRUE	0.0059225	15	887	5	0.0056370	0.3333333	GO:0033631	GO:BP	cell-cell adhesion mediated by integrin	16175	8332	GO:00336….
query_1	TRUE	0.0059564	77	887	12	0.0135287	0.1558442	GO:0032088	GO:BP	negative regulation of NF-kappaB transcription factor activity	16175	7355	GO:0043433
query_1	TRUE	0.0059564	22	887	6	0.0067644	0.2727273	GO:0070232	GO:BP	regulation of T cell apoptotic process	16175	16002	GO:00702….
query_1	TRUE	0.0060060	999	887	78	0.0879369	0.0780781	GO:0051247	GO:BP	positive regulation of protein metabolic process	16175	13594	GO:00106….
query_1	TRUE	0.0062998	366	887	35	0.0394589	0.0956284	GO:0051336	GO:BP	regulation of hydrolase activity	16175	13663	GO:0050790
query_1	TRUE	0.0066597	78	887	12	0.0135287	0.1538462	GO:1903035	GO:BP	negative regulation of response to wounding	16175	22715	GO:00096….
query_1	TRUE	0.0066597	78	887	12	0.0135287	0.1538462	GO:0046330	GO:BP	positive regulation of JNK cascade	16175	12063	GO:00072….
query_1	TRUE	0.0066597	78	887	12	0.0135287	0.1538462	GO:0061844	GO:BP	antimicrobial humoral immune response mediated by antimicrobial peptide	16175	15685	GO:0019730
query_1	TRUE	0.0067353	111	887	15	0.0169109	0.1351351	GO:0008037	GO:BP	cell recognition	16175	3099	GO:0009987
query_1	TRUE	0.0071032	467	887	42	0.0473506	0.0899358	GO:0055080	GO:BP	monoatomic cation homeostasis	16175	14233	GO:0050801
query_1	TRUE	0.0073301	301	887	30	0.0338219	0.0996678	GO:0051347	GO:BP	positive regulation of transferase activity	16175	13674	GO:00430….
query_1	TRUE	0.0075927	23	887	6	0.0067644	0.2608696	GO:0002418	GO:BP	immune response to tumor cell	16175	942	GO:00023….
query_1	TRUE	0.0075927	23	887	6	0.0067644	0.2608696	GO:0035458	GO:BP	cellular response to interferon-beta	16175	9046	GO:00354….
query_1	TRUE	0.0075927	23	887	6	0.0067644	0.2608696	GO:0034114	GO:BP	regulation of heterotypic cell-cell adhesion	16175	8422	GO:00224….
query_1	TRUE	0.0078310	69	887	11	0.0124014	0.1594203	GO:1904427	GO:BP	positive regulation of calcium ion transmembrane transport	16175	23809	GO:00519….
query_1	TRUE	0.0078310	148	887	18	0.0202931	0.1216216	GO:0017157	GO:BP	regulation of exocytosis	16175	5287	GO:00068….
query_1	TRUE	0.0079568	59	887	10	0.0112740	0.1694915	GO:0002062	GO:BP	chondrocyte differentiation	16175	653	GO:00301….
query_1	TRUE	0.0080249	113	887	15	0.0169109	0.1327434	GO:2001236	GO:BP	regulation of extrinsic apoptotic signaling pathway	16175	26425	GO:00971….
query_1	TRUE	0.0080643	16	887	5	0.0056370	0.3125000	GO:0043371	GO:BP	negative regulation of CD4-positive, alpha-beta T cell differentiation	16175	10648	GO:00433….
query_1	TRUE	0.0080643	16	887	5	0.0056370	0.3125000	GO:0061081	GO:BP	positive regulation of myeloid leukocyte cytokine production involved in immune response	16175	15197	GO:00027….
query_1	TRUE	0.0081167	442	887	40	0.0450958	0.0904977	GO:0051046	GO:BP	regulation of secretion	16175	13456	GO:00469….
query_1	TRUE	0.0081770	631	887	53	0.0597520	0.0839937	GO:0022603	GO:BP	regulation of anatomical structure morphogenesis	16175	6611	GO:00096….
query_1	TRUE	0.0083626	91	887	13	0.0146561	0.1428571	GO:0051346	GO:BP	negative regulation of hydrolase activity	16175	13673	GO:00430….
query_1	TRUE	0.0087286	114	887	15	0.0169109	0.1315789	GO:1904064	GO:BP	positive regulation of cation transmembrane transport	16175	23503	GO:00347….
query_1	TRUE	0.0088107	50	887	9	0.0101466	0.1800000	GO:0001706	GO:BP	endoderm formation	16175	398	GO:00017….
query_1	TRUE	0.0088996	10	887	4	0.0045096	0.4000000	GO:0090103	GO:BP	cochlea morphogenesis	16175	18021	GO:00424….
query_1	TRUE	0.0088996	10	887	4	0.0045096	0.4000000	GO:0070669	GO:BP	response to interleukin-2	16175	16250	GO:0034097
query_1	TRUE	0.0088996	10	887	4	0.0045096	0.4000000	GO:0021783	GO:BP	preganglionic parasympathetic fiber development	16175	6361	GO:00074….
query_1	TRUE	0.0088996	10	887	4	0.0045096	0.4000000	GO:0035590	GO:BP	purinergic nucleotide receptor signaling pathway	16175	9107	GO:0007166
query_1	TRUE	0.0088996	10	887	4	0.0045096	0.4000000	GO:0051770	GO:BP	positive regulation of nitric-oxide synthase biosynthetic process	16175	13926	GO:00105….
query_1	TRUE	0.0088996	10	887	4	0.0045096	0.4000000	GO:1905155	GO:BP	positive regulation of membrane invagination	16175	24403	GO:00103….
query_1	TRUE	0.0088996	10	887	4	0.0045096	0.4000000	GO:0033632	GO:BP	regulation of cell-cell adhesion mediated by integrin	16175	8333	GO:00224….
query_1	TRUE	0.0088996	10	887	4	0.0045096	0.4000000	GO:0045779	GO:BP	negative regulation of bone resorption	16175	11613	GO:00451….
query_1	TRUE	0.0088996	10	887	4	0.0045096	0.4000000	GO:0060100	GO:BP	positive regulation of phagocytosis, engulfment	16175	14356	GO:00069….
query_1	TRUE	0.0088996	10	887	4	0.0045096	0.4000000	GO:0061043	GO:BP	regulation of vascular wound healing	16175	15159	GO:00457….
query_1	TRUE	0.0089006	60	887	10	0.0112740	0.1666667	GO:0043903	GO:BP	regulation of biological process involved in symbiotic interaction	16175	10855	GO:00444….
query_1	TRUE	0.0089006	60	887	10	0.0112740	0.1666667	GO:0002244	GO:BP	hematopoietic progenitor cell differentiation	16175	777	GO:00300….
query_1	TRUE	0.0090030	32	887	7	0.0078918	0.2187500	GO:0002920	GO:BP	regulation of humoral immune response	16175	1430	GO:00069….
query_1	TRUE	0.0091687	5	887	3	0.0033822	0.6000000	GO:0045590	GO:BP	negative regulation of regulatory T cell differentiation	16175	11441	GO:00450….
query_1	TRUE	0.0091687	5	887	3	0.0033822	0.6000000	GO:0043313	GO:BP	regulation of neutrophil degranulation	16175	10621	GO:00028….
query_1	TRUE	0.0091687	5	887	3	0.0033822	0.6000000	GO:0038159	GO:BP	C-X-C chemokine receptor CXCR4 signaling pathway	16175	9738	GO:0070098
query_1	TRUE	0.0091687	5	887	3	0.0033822	0.6000000	GO:0061757	GO:BP	leukocyte adhesion to arterial endothelial cell	16175	15651	GO:0061756
query_1	TRUE	0.0091687	5	887	3	0.0033822	0.6000000	GO:0048006	GO:BP	antigen processing and presentation, endogenous lipid antigen via MHC class Ib	16175	12462	GO:00198….
query_1	TRUE	0.0091687	5	887	3	0.0033822	0.6000000	GO:0048003	GO:BP	antigen processing and presentation of lipid antigen via MHC class Ib	16175	12461	GO:0002475
query_1	TRUE	0.0091687	5	887	3	0.0033822	0.6000000	GO:0002638	GO:BP	negative regulation of immunoglobulin production	16175	1159	GO:00023….
query_1	TRUE	0.0091687	5	887	3	0.0033822	0.6000000	GO:0048007	GO:BP	antigen processing and presentation, exogenous lipid antigen via MHC class Ib	16175	12463	GO:00198….
query_1	TRUE	0.0091687	5	887	3	0.0033822	0.6000000	GO:0070487	GO:BP	monocyte aggregation	16175	16148	GO:0070486
query_1	TRUE	0.0091687	5	887	3	0.0033822	0.6000000	GO:0046643	GO:BP	regulation of gamma-delta T cell activation	16175	12280	GO:00466….
query_1	TRUE	0.0091687	5	887	3	0.0033822	0.6000000	GO:0140639	GO:BP	positive regulation of pyroptotic inflammatory response	16175	19843	GO:00507….
query_1	TRUE	0.0091687	41	887	8	0.0090192	0.1951220	GO:0140894	GO:BP	endolysosomal toll-like receptor signaling pathway	16175	19926	GO:0002753
query_1	TRUE	0.0092961	24	887	6	0.0067644	0.2500000	GO:0006953	GO:BP	acute-phase response	16175	2584	GO:0002526
query_1	TRUE	0.0094232	475	887	42	0.0473506	0.0884211	GO:0050801	GO:BP	monoatomic ion homeostasis	16175	13267	GO:0048878
query_1	TRUE	0.0095622	71	887	11	0.0124014	0.1549296	GO:0060761	GO:BP	negative regulation of response to cytokine stimulus	16175	14929	GO:00340….
query_1	TRUE	0.0095622	307	887	30	0.0338219	0.0977199	GO:0051051	GO:BP	negative regulation of transport	16175	13461	GO:00068….
query_1	TRUE	0.0098683	51	887	9	0.0101466	0.1764706	GO:0032648	GO:BP	regulation of interferon-beta production	16175	7695	GO:00324….
query_1	TRUE	0.0098683	51	887	9	0.0101466	0.1764706	GO:0032608	GO:BP	interferon-beta production	16175	7656	GO:0032606
query_1	TRUE	0.0100697	116	887	15	0.0169109	0.1293103	GO:0030832	GO:BP	regulation of actin filament length	16175	6917	GO:00325….
query_1	TRUE	0.0102303	881	887	69	0.0777903	0.0783201	GO:0051130	GO:BP	positive regulation of cellular component organization	16175	13514	GO:00160….
query_1	TRUE	0.0102805	140	887	17	0.0191657	0.1214286	GO:0007189	GO:BP	adenylate cyclase-activating G protein-coupled receptor signaling pathway	16175	2747	GO:0007188
query_1	TRUE	0.0104734	17	887	5	0.0056370	0.2941176	GO:0032682	GO:BP	negative regulation of chemokine production	16175	7728	GO:00018….
query_1	TRUE	0.0106178	42	887	8	0.0090192	0.1904762	GO:0010466	GO:BP	negative regulation of peptidase activity	16175	4159	GO:00458….
query_1	TRUE	0.0106312	33	887	7	0.0078918	0.2121212	GO:0002673	GO:BP	regulation of acute inflammatory response	16175	1191	GO:00025….
query_1	TRUE	0.0108985	153	887	18	0.0202931	0.1176471	GO:0008154	GO:BP	actin polymerization or depolymerization	16175	3127	GO:0007015
query_1	TRUE	0.0110716	129	887	16	0.0180383	0.1240310	GO:1904018	GO:BP	positive regulation of vasculature development	16175	23459	GO:00019….
query_1	TRUE	0.0110965	283	887	28	0.0315671	0.0989399	GO:0001501	GO:BP	skeletal system development	16175	318	GO:0048731
query_1	TRUE	0.0111663	62	887	10	0.0112740	0.1612903	GO:0062208	GO:BP	positive regulation of pattern recognition receptor signaling pathway	16175	15864	GO:00022….
query_1	TRUE	0.0112391	52	887	9	0.0101466	0.1730769	GO:0046849	GO:BP	bone remodeling	16175	12401	GO:0048771
query_1	TRUE	0.0114615	25	887	6	0.0067644	0.2400000	GO:1904994	GO:BP	regulation of leukocyte adhesion to vascular endothelial cell	16175	24279	GO:00617….
query_1	TRUE	0.0114615	25	887	6	0.0067644	0.2400000	GO:0032814	GO:BP	regulation of natural killer cell activation	16175	7838	GO:00301….
query_1	TRUE	0.0116283	284	887	28	0.0315671	0.0985915	GO:0010959	GO:BP	regulation of metal ion transport	16175	4536	GO:00300….
query_1	TRUE	0.0120278	84	887	12	0.0135287	0.1428571	GO:0033209	GO:BP	tumor necrosis factor-mediated signaling pathway	16175	8075	GO:00192….
query_1	TRUE	0.0122927	43	887	8	0.0090192	0.1860465	GO:0050850	GO:BP	positive regulation of calcium-mediated signaling	16175	13298	GO:00197….
query_1	TRUE	0.0125466	63	887	10	0.0112740	0.1587302	GO:0008625	GO:BP	extrinsic apoptotic signaling pathway via death domain receptors	16175	3214	GO:0097191
query_1	TRUE	0.0125991	34	887	7	0.0078918	0.2058824	GO:1902041	GO:BP	regulation of extrinsic apoptotic signaling pathway via death domain receptors	16175	21964	GO:00086….
query_1	TRUE	0.0125991	34	887	7	0.0078918	0.2058824	GO:0045214	GO:BP	sarcomere organization	16175	11327	GO:00302….
query_1	TRUE	0.0127364	11	887	4	0.0045096	0.3636364	GO:0090102	GO:BP	cochlea development	16175	18020	GO:00488….
query_1	TRUE	0.0127364	11	887	4	0.0045096	0.3636364	GO:0045061	GO:BP	thymic T cell selection	16175	11259	GO:00330….
query_1	TRUE	0.0127364	11	887	4	0.0045096	0.3636364	GO:0034154	GO:BP	toll-like receptor 7 signaling pathway	16175	8462	GO:0140894
query_1	TRUE	0.0127364	11	887	4	0.0045096	0.3636364	GO:0036006	GO:BP	cellular response to macrophage colony-stimulating factor stimulus	16175	9389	GO:00360….
query_1	TRUE	0.0127364	967	887	74	0.0834273	0.0765253	GO:0031399	GO:BP	regulation of protein modification process	16175	7155	GO:00362….
query_1	TRUE	0.0127364	11	887	4	0.0045096	0.3636364	GO:0045579	GO:BP	positive regulation of B cell differentiation	16175	11430	GO:00301….
query_1	TRUE	0.0127364	11	887	4	0.0045096	0.3636364	GO:1901731	GO:BP	positive regulation of platelet aggregation	16175	21675	GO:00341….
query_1	TRUE	0.0127364	11	887	4	0.0045096	0.3636364	GO:0048532	GO:BP	anatomical structure arrangement	16175	12813	GO:00096….
query_1	TRUE	0.0127364	11	887	4	0.0045096	0.3636364	GO:0036005	GO:BP	response to macrophage colony-stimulating factor	16175	9388	GO:0034097
query_1	TRUE	0.0134866	18	887	5	0.0056370	0.2777778	GO:2000353	GO:BP	positive regulation of endothelial cell apoptotic process	16175	25672	GO:00430….
query_1	TRUE	0.0134866	18	887	5	0.0056370	0.2777778	GO:0045624	GO:BP	positive regulation of T-helper cell differentiation	16175	11475	GO:00026….
query_1	TRUE	0.0134866	18	887	5	0.0056370	0.2777778	GO:0043032	GO:BP	positive regulation of macrophage activation	16175	10487	GO:00026….
query_1	TRUE	0.0138991	26	887	6	0.0067644	0.2307692	GO:2000316	GO:BP	regulation of T-helper 17 type immune response	16175	25638	GO:00028….
query_1	TRUE	0.0138991	64	887	10	0.0112740	0.1562500	GO:1990849	GO:BP	vacuolar localization	16175	25315	GO:0051640
query_1	TRUE	0.0138991	26	887	6	0.0067644	0.2307692	GO:0090330	GO:BP	regulation of platelet aggregation	16175	18210	GO:00105….
query_1	TRUE	0.0138991	26	887	6	0.0067644	0.2307692	GO:0071676	GO:BP	negative regulation of mononuclear cell migration	16175	16849	GO:00026….
query_1	TRUE	0.0138991	64	887	10	0.0112740	0.1562500	GO:0032418	GO:BP	lysosome localization	16175	7556	GO:1990849
query_1	TRUE	0.0140225	44	887	8	0.0090192	0.1818182	GO:0048260	GO:BP	positive regulation of receptor-mediated endocytosis	16175	12612	GO:00068….
query_1	TRUE	0.0143318	54	887	9	0.0101466	0.1666667	GO:0031638	GO:BP	zymogen activation	16175	7248	GO:0016485
query_1	TRUE	0.0143318	54	887	9	0.0101466	0.1666667	GO:0052372	GO:BP	modulation by symbiont of entry into host	16175	14118	GO:00439….
query_1	TRUE	0.0147093	35	887	7	0.0078918	0.2000000	GO:0097242	GO:BP	amyloid-beta clearance	16175	18557	GO:0032501
query_1	TRUE	0.0160068	534	887	45	0.0507328	0.0842697	GO:0055082	GO:BP	intracellular chemical homeostasis	16175	14235	GO:00197….
query_1	TRUE	0.0161716	45	887	8	0.0090192	0.1777778	GO:0055013	GO:BP	cardiac muscle cell development	16175	14202	GO:00550….
query_1	TRUE	0.0161898	2128	887	145	0.1634724	0.0681391	GO:0065008	GO:BP	regulation of biological quality	16175	15891	GO:0065007
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:1904999	GO:BP	positive regulation of leukocyte adhesion to arterial endothelial cell	16175	24284	GO:00617….
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:1904170	GO:BP	regulation of bleb assembly	16175	23583	GO:00320….
query_1	TRUE	0.0162132	6	887	3	0.0033822	0.5000000	GO:0060729	GO:BP	intestinal epithelial structure maintenance	16175	14898	GO:0030277
query_1	TRUE	0.0162132	36	887	7	0.0078918	0.1944444	GO:0046850	GO:BP	regulation of bone remodeling	16175	12402	GO:00341….
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:1904172	GO:BP	positive regulation of bleb assembly	16175	23585	GO:00320….
query_1	TRUE	0.0162132	19	887	5	0.0056370	0.2631579	GO:0002335	GO:BP	mature B cell differentiation	16175	867	GO:0030183
query_1	TRUE	0.0162132	6	887	3	0.0033822	0.5000000	GO:0097490	GO:BP	sympathetic neuron projection extension	16175	18674	GO:1990138
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:0035700	GO:BP	astrocyte chemotaxis	16175	9174	GO:00436….
query_1	TRUE	0.0162132	6	887	3	0.0033822	0.5000000	GO:0032306	GO:BP	regulation of prostaglandin secretion	16175	7476	GO:00323….
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:0002296	GO:BP	T-helper 1 cell lineage commitment	16175	828	GO:00022….
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:1904270	GO:BP	pyroptosome complex assembly	16175	23661	GO:0065003
query_1	TRUE	0.0162132	19	887	5	0.0056370	0.2631579	GO:0016553	GO:BP	base conversion or substitution editing	16175	5244	GO:0009451
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:1904155	GO:BP	DN2 thymocyte differentiation	16175	23576	GO:0033077
query_1	TRUE	0.0162132	19	887	5	0.0056370	0.2631579	GO:0090026	GO:BP	positive regulation of monocyte chemotaxis	16175	17960	GO:00025….
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:0034125	GO:BP	negative regulation of MyD88-dependent toll-like receptor signaling pathway	16175	8433	GO:00027….
query_1	TRUE	0.0162132	27	887	6	0.0067644	0.2222222	GO:0031641	GO:BP	regulation of myelination	16175	7251	GO:00425….
query_1	TRUE	0.0162132	6	887	3	0.0033822	0.5000000	GO:0072679	GO:BP	thymocyte migration	16175	17497	GO:0072678
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:0033082	GO:BP	regulation of extrathymic T cell differentiation	16175	8030	GO:00330….
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:0002270	GO:BP	plasmacytoid dendritic cell activation	16175	802	GO:0045321
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:0072377	GO:BP	blood coagulation, common pathway	16175	17374	GO:00723….
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:0045914	GO:BP	negative regulation of catecholamine metabolic process	16175	11708	GO:00065….
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:0045963	GO:BP	negative regulation of dopamine metabolic process	16175	11755	GO:00420….
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:1902216	GO:BP	positive regulation of interleukin-4-mediated signaling pathway	16175	22115	GO:00019….
query_1	TRUE	0.0162132	19	887	5	0.0056370	0.2631579	GO:1900227	GO:BP	positive regulation of NLRP3 inflammasome complex assembly	16175	20499	GO:00313….
query_1	TRUE	0.0162132	19	887	5	0.0056370	0.2631579	GO:0030449	GO:BP	regulation of complement activation	16175	6807	GO:00026….
query_1	TRUE	0.0162132	6	887	3	0.0033822	0.5000000	GO:0060075	GO:BP	regulation of resting membrane potential	16175	14336	GO:0042391
query_1	TRUE	0.0162132	55	887	9	0.0101466	0.1636364	GO:0051289	GO:BP	protein homotetramerization	16175	13621	GO:00512….
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:0033078	GO:BP	extrathymic T cell differentiation	16175	8026	GO:0030217
query_1	TRUE	0.0162132	404	887	36	0.0405862	0.0891089	GO:1903530	GO:BP	regulation of secretion by cell	16175	23080	GO:00329….
query_1	TRUE	0.0162132	6	887	3	0.0033822	0.5000000	GO:0051715	GO:BP	cytolysis in another organism	16175	13908	GO:00198….
query_1	TRUE	0.0162132	885	887	68	0.0766629	0.0768362	GO:0006811	GO:BP	monoatomic ion transport	16175	2491	GO:0006810
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:0140973	GO:BP	positive regulation of AIM2 inflammasome complex assembly	16175	19957	GO:00313….
query_1	TRUE	0.0162132	6	887	3	0.0033822	0.5000000	GO:1903969	GO:BP	regulation of response to macrophage colony-stimulating factor	16175	23426	GO:00360….
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:1903971	GO:BP	positive regulation of response to macrophage colony-stimulating factor	16175	23428	GO:00360….
query_1	TRUE	0.0162132	6	887	3	0.0033822	0.5000000	GO:1903972	GO:BP	regulation of cellular response to macrophage colony-stimulating factor stimulus	16175	23429	GO:00360….
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:1903974	GO:BP	positive regulation of cellular response to macrophage colony-stimulating factor stimulus	16175	23431	GO:00360….
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:0045658	GO:BP	regulation of neutrophil differentiation	16175	11509	GO:00302….
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:0140105	GO:BP	interleukin-10-mediated signaling pathway	16175	19666	GO:0019221
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:0140039	GO:BP	cell-cell adhesion in response to extracellular stimulus	16175	19643	GO:00517….
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:0060346	GO:BP	bone trabecula formation	16175	14557	GO:00487….
query_1	TRUE	0.0162132	19	887	5	0.0056370	0.2631579	GO:0043302	GO:BP	positive regulation of leukocyte degranulation	16175	10610	GO:00026….
query_1	TRUE	0.0162132	6	887	3	0.0033822	0.5000000	GO:1904141	GO:BP	positive regulation of microglial cell migration	16175	23563	GO:19039….
query_1	TRUE	0.0162132	36	887	7	0.0078918	0.1944444	GO:0003009	GO:BP	skeletal muscle contraction	16175	1460	GO:00069….
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:0090291	GO:BP	negative regulation of osteoclast proliferation	16175	18175	GO:00021….
query_1	TRUE	0.0162132	6	887	3	0.0033822	0.5000000	GO:0021785	GO:BP	branchiomotor neuron axon guidance	16175	6363	GO:0008045
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:2000361	GO:BP	regulation of prostaglandin-E synthase activity	16175	25680	GO:0010911
query_1	TRUE	0.0162132	19	887	5	0.0056370	0.2631579	GO:0002052	GO:BP	positive regulation of neuroblast proliferation	16175	651	GO:00074….
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:0002587	GO:BP	negative regulation of antigen processing and presentation of peptide antigen via MHC class II	16175	1108	GO:00024….
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:2000363	GO:BP	positive regulation of prostaglandin-E synthase activity	16175	25681	GO:00109….
query_1	TRUE	0.0162132	6	887	3	0.0033822	0.5000000	GO:0048934	GO:BP	peripheral nervous system neuron differentiation	16175	13174	GO:00074….
query_1	TRUE	0.0162132	6	887	3	0.0033822	0.5000000	GO:0032741	GO:BP	positive regulation of interleukin-18 production	16175	7785	GO:00018….
query_1	TRUE	0.0162132	6	887	3	0.0033822	0.5000000	GO:0048935	GO:BP	peripheral nervous system neuron development	16175	13175	GO:00486….
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:2000446	GO:BP	regulation of macrophage migration inhibitory factor signaling pathway	16175	25761	GO:00019….
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:0038124	GO:BP	toll-like receptor TLR6:TLR2 signaling pathway	16175	9715	GO:0002224
query_1	TRUE	0.0162132	6	887	3	0.0033822	0.5000000	GO:0042270	GO:BP	protection from natural killer cell mediated cytotoxicity	16175	10068	GO:0045953
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:2000448	GO:BP	positive regulation of macrophage migration inhibitory factor signaling pathway	16175	25763	GO:00019….
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:0002582	GO:BP	positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	16175	1103	GO:00025….
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:2000458	GO:BP	regulation of astrocyte chemotaxis	16175	25773	GO:00357….
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:2000471	GO:BP	regulation of hematopoietic stem cell migration	16175	25783	GO:00303….
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:2000473	GO:BP	positive regulation of hematopoietic stem cell migration	16175	25785	GO:00303….
query_1	TRUE	0.0162132	6	887	3	0.0033822	0.5000000	GO:0021637	GO:BP	trigeminal nerve structural organization	16175	6220	GO:00216….
query_1	TRUE	0.0162132	6	887	3	0.0033822	0.5000000	GO:0030854	GO:BP	positive regulation of granulocyte differentiation	16175	6937	GO:00027….
query_1	TRUE	0.0162132	6	887	3	0.0033822	0.5000000	GO:2000669	GO:BP	negative regulation of dendritic cell apoptotic process	16175	25944	GO:00970….
query_1	TRUE	0.0162132	6	887	3	0.0033822	0.5000000	GO:0001865	GO:BP	NK T cell differentiation	16175	502	GO:0046632
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:0002585	GO:BP	positive regulation of antigen processing and presentation of peptide antigen	16175	1106	GO:00025….
query_1	TRUE	0.0162132	6	887	3	0.0033822	0.5000000	GO:0070106	GO:BP	interleukin-27-mediated signaling pathway	16175	15918	GO:0019221
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:0042496	GO:BP	detection of diacyl bacterial lipopeptide	16175	10224	GO:00703….
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:0042495	GO:BP	detection of triacyl bacterial lipopeptide	16175	10223	GO:00703….
query_1	TRUE	0.0162132	19	887	5	0.0056370	0.2631579	GO:2000319	GO:BP	regulation of T-helper 17 cell differentiation	16175	25641	GO:00456….
query_1	TRUE	0.0162132	6	887	3	0.0033822	0.5000000	GO:0021636	GO:BP	trigeminal nerve morphogenesis	16175	6219	GO:00215….
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:2000349	GO:BP	negative regulation of CD40 signaling pathway	16175	25668	GO:00099….
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:0035691	GO:BP	macrophage migration inhibitory factor signaling pathway	16175	9167	GO:0019221
query_1	TRUE	0.0162132	2	887	2	0.0022548	1.0000000	GO:0002588	GO:BP	positive regulation of antigen processing and presentation of peptide antigen via MHC class II	16175	1109	GO:00024….
query_1	TRUE	0.0162248	463	887	40	0.0450958	0.0863931	GO:0097190	GO:BP	apoptotic signaling pathway	16175	18534	GO:00069….
query_1	TRUE	0.0163043	279	887	27	0.0304397	0.0967742	GO:0031589	GO:BP	cell-substrate adhesion	16175	7233	GO:0007155
query_1	TRUE	0.0165024	77	887	11	0.0124014	0.1428571	GO:0043406	GO:BP	positive regulation of MAP kinase activity	16175	10674	GO:00434….
query_1	TRUE	0.0167044	12	887	4	0.0045096	0.3333333	GO:0048486	GO:BP	parasympathetic nervous system development	16175	12780	GO:00484….
query_1	TRUE	0.0167044	12	887	4	0.0045096	0.3333333	GO:0035666	GO:BP	TRIF-dependent toll-like receptor signaling pathway	16175	9146	GO:0002756
query_1	TRUE	0.0167044	12	887	4	0.0045096	0.3333333	GO:0002430	GO:BP	complement receptor mediated signaling pathway	16175	953	GO:0002429
query_1	TRUE	0.0167044	12	887	4	0.0045096	0.3333333	GO:0042454	GO:BP	ribonucleoside catabolic process	16175	10193	GO:00091….
query_1	TRUE	0.0167044	12	887	4	0.0045096	0.3333333	GO:0002357	GO:BP	defense response to tumor cell	16175	889	GO:00023….
query_1	TRUE	0.0170893	56	887	9	0.0101466	0.1607143	GO:0034103	GO:BP	regulation of tissue remodeling	16175	8411	GO:00487….
query_1	TRUE	0.0173007	407	887	36	0.0405862	0.0884521	GO:0007015	GO:BP	actin filament organization	16175	2624	GO:00300….
query_1	TRUE	0.0173007	350	887	32	0.0360767	0.0914286	GO:0016032	GO:BP	viral process	16175	5071	GO:0008150
query_1	TRUE	0.0180069	67	887	10	0.0112740	0.1492537	GO:0001960	GO:BP	negative regulation of cytokine-mediated signaling pathway	16175	569	GO:00019….
query_1	TRUE	0.0186211	125	887	15	0.0169109	0.1200000	GO:0045766	GO:BP	positive regulation of angiogenesis	16175	11602	GO:00015….
query_1	TRUE	0.0186852	113	887	14	0.0157835	0.1238938	GO:0008064	GO:BP	regulation of actin polymerization or depolymerization	16175	3113	GO:00081….
query_1	TRUE	0.0189395	28	887	6	0.0067644	0.2142857	GO:0030866	GO:BP	cortical actin cytoskeleton organization	16175	6947	GO:00300….
query_1	TRUE	0.0189395	28	887	6	0.0067644	0.2142857	GO:0030224	GO:BP	monocyte differentiation	16175	6732	GO:00025….
query_1	TRUE	0.0191563	57	887	9	0.0101466	0.1578947	GO:0007492	GO:BP	endoderm development	16175	2978	GO:0009888
query_1	TRUE	0.0191563	57	887	9	0.0101466	0.1578947	GO:0006809	GO:BP	nitric oxide biosynthetic process	16175	2489	GO:00090….
query_1	TRUE	0.0191563	57	887	9	0.0101466	0.1578947	GO:0030193	GO:BP	regulation of blood coagulation	16175	6704	GO:00075….
query_1	TRUE	0.0192888	90	887	12	0.0135287	0.1333333	GO:0097305	GO:BP	response to alcohol	16175	18586	GO:1901700
query_1	TRUE	0.0194611	242	887	24	0.0270575	0.0991736	GO:0051056	GO:BP	regulation of small GTPase mediated signal transduction	16175	13466	GO:00072….
query_1	TRUE	0.0195977	47	887	8	0.0090192	0.1702128	GO:0001656	GO:BP	metanephros development	16175	370	GO:0001822
query_1	TRUE	0.0200898	20	887	5	0.0056370	0.2500000	GO:0010463	GO:BP	mesenchymal cell proliferation	16175	4157	GO:0008283
query_1	TRUE	0.0200898	20	887	5	0.0056370	0.2500000	GO:0030277	GO:BP	maintenance of gastrointestinal epithelium	16175	6754	GO:00106….
query_1	TRUE	0.0200898	20	887	5	0.0056370	0.2500000	GO:0060142	GO:BP	regulation of syncytium formation by plasma membrane fusion	16175	14386	GO:00007….
query_1	TRUE	0.0200898	20	887	5	0.0056370	0.2500000	GO:1905523	GO:BP	positive regulation of macrophage migration	16175	24699	GO:00716….
query_1	TRUE	0.0214443	58	887	9	0.0101466	0.1551724	GO:1900046	GO:BP	regulation of hemostasis	16175	20348	GO:00075….
query_1	TRUE	0.0216989	38	887	7	0.0078918	0.1842105	GO:0021675	GO:BP	nerve development	16175	6258	GO:00073….
query_1	TRUE	0.0216989	38	887	7	0.0078918	0.1842105	GO:0061515	GO:BP	myeloid cell development	16175	15516	GO:00300….
query_1	TRUE	0.0216989	38	887	7	0.0078918	0.1842105	GO:0032728	GO:BP	positive regulation of interferon-beta production	16175	7773	GO:00324….
query_1	TRUE	0.0217559	80	887	11	0.0124014	0.1375000	GO:0030278	GO:BP	regulation of ossification	16175	6755	GO:00015….
query_1	TRUE	0.0217872	165	887	18	0.0202931	0.1090909	GO:0001659	GO:BP	temperature homeostasis	16175	373	GO:0048871
query_1	TRUE	0.0221947	48	887	8	0.0090192	0.1666667	GO:0061097	GO:BP	regulation of protein tyrosine kinase activity	16175	15207	GO:00458….
query_1	TRUE	0.0224062	13	887	4	0.0045096	0.3076923	GO:0150078	GO:BP	positive regulation of neuroinflammatory response	16175	20130	GO:00507….
query_1	TRUE	0.0224062	29	887	6	0.0067644	0.2068966	GO:0045124	GO:BP	regulation of bone resorption	16175	11290	GO:00454….
query_1	TRUE	0.0224062	13	887	4	0.0045096	0.3076923	GO:0002830	GO:BP	positive regulation of type 2 immune response	16175	1340	GO:00028….
query_1	TRUE	0.0224062	13	887	4	0.0045096	0.3076923	GO:0002922	GO:BP	positive regulation of humoral immune response	16175	1432	GO:00029….
query_1	TRUE	0.0224062	29	887	6	0.0067644	0.2068966	GO:0039694	GO:BP	viral RNA genome replication	16175	9871	GO:00190….
query_1	TRUE	0.0224062	13	887	4	0.0045096	0.3076923	GO:2000402	GO:BP	negative regulation of lymphocyte migration	16175	25717	GO:00716….
query_1	TRUE	0.0224062	13	887	4	0.0045096	0.3076923	GO:0051767	GO:BP	nitric-oxide synthase biosynthetic process	16175	13924	GO:0009059
query_1	TRUE	0.0224062	13	887	4	0.0045096	0.3076923	GO:0051769	GO:BP	regulation of nitric-oxide synthase biosynthetic process	16175	13925	GO:00105….
query_1	TRUE	0.0224062	13	887	4	0.0045096	0.3076923	GO:0031665	GO:BP	negative regulation of lipopolysaccharide-mediated signaling pathway	16175	7269	GO:00028….
query_1	TRUE	0.0226664	92	887	12	0.0135287	0.1304348	GO:0048771	GO:BP	tissue remodeling	16175	13020	GO:0032501
query_1	TRUE	0.0229492	192	887	20	0.0225479	0.1041667	GO:0007160	GO:BP	cell-matrix adhesion	16175	2724	GO:0031589
query_1	TRUE	0.0237045	59	887	9	0.0101466	0.1525424	GO:0050818	GO:BP	regulation of coagulation	16175	13280	GO:00508….
query_1	TRUE	0.0237045	59	887	9	0.0101466	0.1525424	GO:0022617	GO:BP	extracellular matrix disassembly	16175	6624	GO:00224….
query_1	TRUE	0.0246711	21	887	5	0.0056370	0.2380952	GO:0046639	GO:BP	negative regulation of alpha-beta T cell differentiation	16175	12276	GO:00455….
query_1	TRUE	0.0246711	21	887	5	0.0056370	0.2380952	GO:0002726	GO:BP	positive regulation of T cell cytokine production	16175	1244	GO:00023….
query_1	TRUE	0.0246711	21	887	5	0.0056370	0.2380952	GO:0031646	GO:BP	positive regulation of nervous system process	16175	7256	GO:00316….
query_1	TRUE	0.0246711	21	887	5	0.0056370	0.2380952	GO:0060055	GO:BP	angiogenesis involved in wound healing	16175	14317	GO:00015….
query_1	TRUE	0.0248110	49	887	8	0.0090192	0.1632653	GO:0039532	GO:BP	negative regulation of cytoplasmic pattern recognition receptor signaling pathway	16175	9805	GO:00026….
query_1	TRUE	0.0248110	7	887	3	0.0033822	0.4285714	GO:0038113	GO:BP	interleukin-9-mediated signaling pathway	16175	9707	GO:00192….
query_1	TRUE	0.0248110	7	887	3	0.0033822	0.4285714	GO:1903753	GO:BP	negative regulation of p38MAPK cascade	16175	23254	GO:00380….
query_1	TRUE	0.0248110	7	887	3	0.0033822	0.4285714	GO:0010912	GO:BP	positive regulation of isomerase activity	16175	4497	GO:00109….
query_1	TRUE	0.0248110	7	887	3	0.0033822	0.4285714	GO:2000562	GO:BP	negative regulation of CD4-positive, alpha-beta T cell proliferation	16175	25863	GO:00357….
query_1	TRUE	0.0248110	7	887	3	0.0033822	0.4285714	GO:0045625	GO:BP	regulation of T-helper 1 cell differentiation	16175	11476	GO:00028….
query_1	TRUE	0.0248110	7	887	3	0.0033822	0.4285714	GO:0010911	GO:BP	regulation of isomerase activity	16175	4496	GO:0050790
query_1	TRUE	0.0248110	7	887	3	0.0033822	0.4285714	GO:0002544	GO:BP	chronic inflammatory response	16175	1065	GO:0006954
query_1	TRUE	0.0248110	7	887	3	0.0033822	0.4285714	GO:0072203	GO:BP	cell proliferation involved in metanephros development	16175	17234	GO:00016….
query_1	TRUE	0.0248110	7	887	3	0.0033822	0.4285714	GO:0035701	GO:BP	hematopoietic stem cell migration	16175	9175	GO:0016477
query_1	TRUE	0.0248110	7	887	3	0.0033822	0.4285714	GO:0051797	GO:BP	regulation of hair follicle development	16175	13944	GO:00019….
query_1	TRUE	0.0248110	7	887	3	0.0033822	0.4285714	GO:0071355	GO:BP	cellular response to interleukin-9	16175	16607	GO:00711….
query_1	TRUE	0.0248110	7	887	3	0.0033822	0.4285714	GO:0002829	GO:BP	negative regulation of type 2 immune response	16175	1339	GO:00028….
query_1	TRUE	0.0248110	7	887	3	0.0033822	0.4285714	GO:0060558	GO:BP	regulation of calcidiol 1-monooxygenase activity	16175	14742	GO:0032768
query_1	TRUE	0.0248110	7	887	3	0.0033822	0.4285714	GO:0033005	GO:BP	positive regulation of mast cell activation	16175	7974	GO:00026….
query_1	TRUE	0.0248803	207	887	21	0.0236753	0.1014493	GO:0014706	GO:BP	striated muscle tissue development	16175	4643	GO:0060537
query_1	TRUE	0.0259132	552	887	45	0.0507328	0.0815217	GO:0035239	GO:BP	tube morphogenesis	16175	8921	GO:00096….
query_1	TRUE	0.0259639	30	887	6	0.0067644	0.2000000	GO:0035456	GO:BP	response to interferon-beta	16175	9044	GO:0034097
query_1	TRUE	0.0259639	30	887	6	0.0067644	0.2000000	GO:0010951	GO:BP	negative regulation of endopeptidase activity	16175	4529	GO:00104….
query_1	TRUE	0.0263315	118	887	14	0.0157835	0.1186441	GO:0046328	GO:BP	regulation of JNK cascade	16175	12061	GO:00072….
query_1	TRUE	0.0269668	182	887	19	0.0214205	0.1043956	GO:0007517	GO:BP	muscle organ development	16175	2999	GO:00485….
query_1	TRUE	0.0270780	305	887	28	0.0315671	0.0918033	GO:0043086	GO:BP	negative regulation of catalytic activity	16175	10519	GO:00440….
query_1	TRUE	0.0277075	50	887	8	0.0090192	0.1600000	GO:0055006	GO:BP	cardiac cell development	16175	14195	GO:00350….
query_1	TRUE	0.0278203	83	887	11	0.0124014	0.1325301	GO:0046718	GO:BP	symbiont entry into host cell	16175	12339	GO:00190….
query_1	TRUE	0.0278203	83	887	11	0.0124014	0.1325301	GO:0046425	GO:BP	regulation of receptor signaling pathway via JAK-STAT	16175	12135	GO:00072….
query_1	TRUE	0.0279939	40	887	7	0.0078918	0.1750000	GO:0043506	GO:BP	regulation of JUN kinase activity	16175	10743	GO:0043405
query_1	TRUE	0.0279939	40	887	7	0.0078918	0.1750000	GO:0010950	GO:BP	positive regulation of endopeptidase activity	16175	4528	GO:00109….
query_1	TRUE	0.0281893	119	887	14	0.0157835	0.1176471	GO:0010001	GO:BP	glial cell differentiation	16175	3822	GO:00301….
query_1	TRUE	0.0282575	510	887	42	0.0473506	0.0823529	GO:0007169	GO:BP	cell surface receptor protein tyrosine kinase signaling pathway	16175	2733	GO:0007167
query_1	TRUE	0.0288646	14	887	4	0.0045096	0.2857143	GO:0046598	GO:BP	positive regulation of viral entry into host cell	16175	12248	GO:00465….
query_1	TRUE	0.0288646	14	887	4	0.0045096	0.2857143	GO:0075294	GO:BP	positive regulation by symbiont of entry into host	16175	17706	GO:00444….
query_1	TRUE	0.0288646	14	887	4	0.0045096	0.2857143	GO:0002486	GO:BP	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent	16175	1009	GO:0002484
query_1	TRUE	0.0288646	14	887	4	0.0045096	0.2857143	GO:0034116	GO:BP	positive regulation of heterotypic cell-cell adhesion	16175	8424	GO:00224….
query_1	TRUE	0.0288646	14	887	4	0.0045096	0.2857143	GO:0002888	GO:BP	positive regulation of myeloid leukocyte mediated immunity	16175	1398	GO:00024….
query_1	TRUE	0.0288646	14	887	4	0.0045096	0.2857143	GO:0043931	GO:BP	ossification involved in bone maturation	16175	10861	GO:00015….
query_1	TRUE	0.0288646	14	887	4	0.0045096	0.2857143	GO:0032930	GO:BP	positive regulation of superoxide anion generation	16175	7921	GO:00329….
query_1	TRUE	0.0288646	14	887	4	0.0045096	0.2857143	GO:0035743	GO:BP	CD4-positive, alpha-beta T cell cytokine production	16175	9208	GO:0002369
query_1	TRUE	0.0288646	14	887	4	0.0045096	0.2857143	GO:0002484	GO:BP	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway	16175	1007	GO:0019885
query_1	TRUE	0.0294876	22	887	5	0.0056370	0.2272727	GO:0038096	GO:BP	Fc-gamma receptor signaling pathway involved in phagocytosis	16175	9696	GO:00024….
query_1	TRUE	0.0294876	22	887	5	0.0056370	0.2272727	GO:0002433	GO:BP	immune response-regulating cell surface receptor signaling pathway involved in phagocytosis	16175	956	GO:00022….
query_1	TRUE	0.0305485	266	887	25	0.0281849	0.0939850	GO:0051960	GO:BP	regulation of nervous system development	16175	14029	GO:00073….
query_1	TRUE	0.0315273	185	887	19	0.0214205	0.1027027	GO:0022604	GO:BP	regulation of cell morphogenesis	16175	6612	GO:00009….
query_1	TRUE	0.0316749	62	887	9	0.0101466	0.1451613	GO:0046209	GO:BP	nitric oxide metabolic process	16175	11975	GO:2001057
query_1	TRUE	0.0316749	41	887	7	0.0078918	0.1707317	GO:0050881	GO:BP	musculoskeletal movement	16175	13325	GO:00508….
query_1	TRUE	0.0316749	41	887	7	0.0078918	0.1707317	GO:0000768	GO:BP	syncytium formation by plasma membrane fusion	16175	234	GO:00069….
query_1	TRUE	0.0316749	62	887	9	0.0101466	0.1451613	GO:0051057	GO:BP	positive regulation of small GTPase mediated signal transduction	16175	13467	GO:00072….
query_1	TRUE	0.0316749	41	887	7	0.0078918	0.1707317	GO:0050879	GO:BP	multicellular organismal movement	16175	13324	GO:0032501
query_1	TRUE	0.0336503	173	887	18	0.0202931	0.1040462	GO:0031032	GO:BP	actomyosin structure organization	16175	7004	GO:0030036
query_1	TRUE	0.0347870	255	887	24	0.0270575	0.0941176	GO:0007610	GO:BP	behavior	16175	3067	GO:0032501
query_1	TRUE	0.0351162	63	887	9	0.0101466	0.1428571	GO:2001057	GO:BP	reactive nitrogen species metabolic process	16175	26299	GO:0008152
query_1	TRUE	0.0351461	32	887	6	0.0067644	0.1875000	GO:0070266	GO:BP	necroptotic process	16175	16027	GO:0097300
query_1	TRUE	0.0355608	23	887	5	0.0056370	0.2173913	GO:0001516	GO:BP	prostaglandin biosynthetic process	16175	326	GO:00066….
query_1	TRUE	0.0355608	23	887	5	0.0056370	0.2173913	GO:0046457	GO:BP	prostanoid biosynthetic process	16175	12165	GO:00066….
query_1	TRUE	0.0355608	23	887	5	0.0056370	0.2173913	GO:0038095	GO:BP	Fc-epsilon receptor signaling pathway	16175	9695	GO:0038093
query_1	TRUE	0.0355608	23	887	5	0.0056370	0.2173913	GO:0072210	GO:BP	metanephric nephron development	16175	17241	GO:00016….
query_1	TRUE	0.0359366	42	887	7	0.0078918	0.1666667	GO:0140253	GO:BP	cell-cell fusion	16175	19722	GO:0009987
query_1	TRUE	0.0359366	42	887	7	0.0078918	0.1666667	GO:0030838	GO:BP	positive regulation of actin filament polymerization	16175	6923	GO:00300….
query_1	TRUE	0.0363488	8	887	3	0.0033822	0.3750000	GO:0071801	GO:BP	regulation of podosome assembly	16175	16915	GO:00432….
query_1	TRUE	0.0363488	8	887	3	0.0033822	0.3750000	GO:0002447	GO:BP	eosinophil mediated immunity	16175	970	GO:0002444
query_1	TRUE	0.0363488	8	887	3	0.0033822	0.3750000	GO:2000343	GO:BP	positive regulation of chemokine (C-X-C motif) ligand 2 production	16175	25662	GO:00327….
query_1	TRUE	0.0363488	123	887	14	0.0157835	0.1138211	GO:0071902	GO:BP	positive regulation of protein serine/threonine kinase activity	16175	16973	GO:00458….
query_1	TRUE	0.0363488	8	887	3	0.0033822	0.3750000	GO:0051709	GO:BP	regulation of killing of cells of another organism	16175	13905	GO:00313….
query_1	TRUE	0.0363488	8	887	3	0.0033822	0.3750000	GO:0002278	GO:BP	eosinophil activation involved in immune response	16175	810	GO:00022….
query_1	TRUE	0.0363488	8	887	3	0.0033822	0.3750000	GO:0042590	GO:BP	antigen processing and presentation of exogenous peptide antigen via MHC class I	16175	10251	GO:00024….
query_1	TRUE	0.0363488	8	887	3	0.0033822	0.3750000	GO:0051712	GO:BP	positive regulation of killing of cells of another organism	16175	13907	GO:00313….
query_1	TRUE	0.0363488	8	887	3	0.0033822	0.3750000	GO:0006957	GO:BP	complement activation, alternative pathway	16175	2588	GO:00069….
query_1	TRUE	0.0363488	8	887	3	0.0033822	0.3750000	GO:0019835	GO:BP	cytolysis	16175	6047	GO:0009987
query_1	TRUE	0.0363488	671	887	52	0.0586246	0.0774963	GO:0034220	GO:BP	monoatomic ion transmembrane transport	16175	8508	GO:00068….
query_1	TRUE	0.0363488	8	887	3	0.0033822	0.3750000	GO:0071104	GO:BP	response to interleukin-9	16175	16454	GO:0034097
query_1	TRUE	0.0363488	8	887	3	0.0033822	0.3750000	GO:0035630	GO:BP	bone mineralization involved in bone maturation	16175	9128	GO:00302….
query_1	TRUE	0.0363488	8	887	3	0.0033822	0.3750000	GO:0043308	GO:BP	eosinophil degranulation	16175	10616	GO:00022….
query_1	TRUE	0.0365712	15	887	4	0.0045096	0.2666667	GO:0010464	GO:BP	regulation of mesenchymal cell proliferation	16175	4158	GO:00104….
query_1	TRUE	0.0365712	15	887	4	0.0045096	0.2666667	GO:0032928	GO:BP	regulation of superoxide anion generation	16175	7919	GO:00425….
query_1	TRUE	0.0365712	15	887	4	0.0045096	0.2666667	GO:0035821	GO:BP	modulation of process of another organism	16175	9269	GO:0044419
query_1	TRUE	0.0370663	626	887	49	0.0552424	0.0782748	GO:0035295	GO:BP	tube development	16175	8953	GO:00072….
query_1	TRUE	0.0385336	551	887	44	0.0496054	0.0798548	GO:1902532	GO:BP	negative regulation of intracellular signal transduction	16175	22341	GO:00099….
query_1	TRUE	0.0385902	431	887	36	0.0405862	0.0835267	GO:1901699	GO:BP	cellular response to nitrogen compound	16175	21652	GO:00708….
query_1	TRUE	0.0399882	76	887	10	0.0112740	0.1315789	GO:0014902	GO:BP	myotube differentiation	16175	4777	GO:0051146
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0002450	GO:BP	B cell antigen processing and presentation	16175	973	GO:00197….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0002465	GO:BP	peripheral tolerance induction	16175	988	GO:0002461
query_1	TRUE	0.0399882	24	887	5	0.0056370	0.2083333	GO:0061760	GO:BP	antifungal innate immune response	16175	15652	GO:00450….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0043315	GO:BP	positive regulation of neutrophil degranulation	16175	10623	GO:00028….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0043316	GO:BP	cytotoxic T cell degranulation	16175	10624	GO:00019….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0038098	GO:BP	sequestering of BMP from receptor via BMP binding	16175	9698	GO:00305….
query_1	TRUE	0.0399882	24	887	5	0.0056370	0.2083333	GO:1903902	GO:BP	positive regulation of viral life cycle	16175	23369	GO:00190….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0016046	GO:BP	detection of fungus	16175	5079	GO:00096….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0006154	GO:BP	adenosine catabolic process	16175	1995	GO:00460….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0016068	GO:BP	type I hypersensitivity	16175	5096	GO:00025….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0045728	GO:BP	respiratory burst after phagocytosis	16175	11570	GO:0002679
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0002581	GO:BP	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	16175	1102	GO:00025….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0110089	GO:BP	regulation of hippocampal neuron apoptotic process	16175	19404	GO:00435….
query_1	TRUE	0.0399882	43	887	7	0.0078918	0.1627907	GO:0043407	GO:BP	negative regulation of MAP kinase activity	16175	10675	GO:00434….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:2001199	GO:BP	negative regulation of dendritic cell differentiation	16175	26399	GO:00970….
query_1	TRUE	0.0399882	43	887	7	0.0078918	0.1627907	GO:0045778	GO:BP	positive regulation of ossification	16175	11612	GO:00015….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0043317	GO:BP	regulation of cytotoxic T cell degranulation	16175	10625	GO:00019….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0150102	GO:BP	negative regulation of monocyte activation	16175	20141	GO:00026….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:2001190	GO:BP	positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell	16175	26390	GO:00022….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0030241	GO:BP	skeletal muscle myosin thick filament assembly	16175	6738	GO:00148….
query_1	TRUE	0.0399882	76	887	10	0.0112740	0.1315789	GO:0051262	GO:BP	protein tetramerization	16175	13609	GO:0051259
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0033239	GO:BP	negative regulation of amine metabolic process	16175	8089	GO:00093….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:1902214	GO:BP	regulation of interleukin-4-mediated signaling pathway	16175	22113	GO:00019….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:1900625	GO:BP	positive regulation of monocyte aggregation	16175	20802	GO:00704….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:1900623	GO:BP	regulation of monocyte aggregation	16175	20800	GO:00704….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0002436	GO:BP	immune complex clearance by monocytes and macrophages	16175	959	GO:0002434
query_1	TRUE	0.0399882	24	887	5	0.0056370	0.2083333	GO:0042730	GO:BP	fibrinolysis	16175	10330	GO:0030195
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0060559	GO:BP	positive regulation of calcidiol 1-monooxygenase activity	16175	14743	GO:00327….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0042756	GO:BP	drinking behavior	16175	10349	GO:0007631
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:1902564	GO:BP	negative regulation of neutrophil activation	16175	22355	GO:00026….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0046103	GO:BP	inosine biosynthetic process	16175	11879	GO:00461….
query_1	TRUE	0.0399882	65	887	9	0.0101466	0.1384615	GO:1902893	GO:BP	regulation of miRNA transcription	16175	22593	GO:00063….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0051136	GO:BP	regulation of NK T cell differentiation	16175	13520	GO:00018….
query_1	TRUE	0.0399882	43	887	7	0.0078918	0.1627907	GO:0006949	GO:BP	syncytium formation	16175	2581	GO:00099….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0160006	GO:BP	Fc receptor-mediated immune complex endocytosis	16175	20192	GO:00068….
query_1	TRUE	0.0399882	24	887	5	0.0056370	0.2083333	GO:0060333	GO:BP	type II interferon-mediated signaling pathway	16175	14545	GO:00713….
query_1	TRUE	0.0399882	100	887	12	0.0135287	0.1200000	GO:0060348	GO:BP	bone development	16175	14559	GO:00015….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0060086	GO:BP	circadian temperature homeostasis	16175	14345	GO:00016….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0110088	GO:BP	hippocampal neuron apoptotic process	16175	19403	GO:0051402
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0043318	GO:BP	negative regulation of cytotoxic T cell degranulation	16175	10626	GO:00019….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0071226	GO:BP	cellular response to molecule of fungal origin	16175	16488	GO:00022….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0071688	GO:BP	striated muscle myosin thick filament assembly	16175	16856	GO:00109….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:1905748	GO:BP	hard palate morphogenesis	16175	24869	GO:0009653
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0090264	GO:BP	regulation of immune complex clearance by monocytes and macrophages	16175	18153	GO:00024….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0090076	GO:BP	relaxation of skeletal muscle	16175	18000	GO:0090075
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0002826	GO:BP	negative regulation of T-helper 1 type immune response	16175	1336	GO:00028….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0071725	GO:BP	response to triacyl bacterial lipopeptide	16175	16885	GO:0070339
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0071659	GO:BP	negative regulation of IP-10 production	16175	16836	GO:00326….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:1904466	GO:BP	positive regulation of matrix metallopeptidase secretion	16175	23844	GO:00507….
query_1	TRUE	0.0399882	24	887	5	0.0056370	0.2083333	GO:0090382	GO:BP	phagosome maturation	16175	18256	GO:0006996
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0071727	GO:BP	cellular response to triacyl bacterial lipopeptide	16175	16887	GO:00712….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0031034	GO:BP	myosin filament assembly	16175	7006	GO:00310….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:1905747	GO:BP	negative regulation of saliva secretion	16175	24868	GO:00465….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:1904093	GO:BP	negative regulation of autophagic cell death	16175	23522	GO:00430….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0071640	GO:BP	regulation of macrophage inflammatory protein 1 alpha production	16175	16817	GO:00326….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0071608	GO:BP	macrophage inflammatory protein-1 alpha production	16175	16794	GO:0032602
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0048769	GO:BP	sarcomerogenesis	16175	13019	GO:00302….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0071626	GO:BP	mastication	16175	16806	GO:0022600
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0007079	GO:BP	mitotic chromosome movement towards spindle pole	16175	2668	GO:00000….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0046968	GO:BP	peptide antigen transport	16175	12453	GO:00158….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:2000670	GO:BP	positive regulation of dendritic cell apoptotic process	16175	25945	GO:00970….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:2000697	GO:BP	negative regulation of epithelial cell differentiation involved in kidney development	16175	25965	GO:00308….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0098583	GO:BP	learned vocalization behavior	16175	18800	GO:00716….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:2000412	GO:BP	positive regulation of thymocyte migration	16175	25727	GO:00726….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0002238	GO:BP	response to molecule of fungal origin	16175	771	GO:00096….
query_1	TRUE	0.0399882	3	887	2	0.0022548	0.6666667	GO:0071691	GO:BP	cardiac muscle thin filament assembly	16175	16859	GO:00070….
query_1	TRUE	0.0425540	152	887	16	0.0180383	0.1052632	GO:0001894	GO:BP	tissue homeostasis	16175	519	GO:00488….
query_1	TRUE	0.0425540	152	887	16	0.0180383	0.1052632	GO:0060249	GO:BP	anatomical structure homeostasis	16175	14466	GO:0048871
query_1	TRUE	0.0431657	44	887	7	0.0078918	0.1590909	GO:0140467	GO:BP	integrated stress response signaling	16175	19788	GO:00335….
query_1	TRUE	0.0431657	44	887	7	0.0078918	0.1590909	GO:1900047	GO:BP	negative regulation of hemostasis	16175	20349	GO:00075….
query_1	TRUE	0.0431657	44	887	7	0.0078918	0.1590909	GO:0030195	GO:BP	negative regulation of blood coagulation	16175	6706	GO:00075….
query_1	TRUE	0.0436577	16	887	4	0.0045096	0.2500000	GO:0060143	GO:BP	positive regulation of syncytium formation by plasma membrane fusion	16175	14387	GO:00007….
query_1	TRUE	0.0436577	16	887	4	0.0045096	0.2500000	GO:0009164	GO:BP	nucleoside catabolic process	16175	3330	GO:00091….
query_1	TRUE	0.0436577	16	887	4	0.0045096	0.2500000	GO:0070207	GO:BP	protein homotrimerization	16175	15988	GO:00512….
query_1	TRUE	0.0436577	16	887	4	0.0045096	0.2500000	GO:0070206	GO:BP	protein trimerization	16175	15987	GO:0051259
query_1	TRUE	0.0436577	16	887	4	0.0045096	0.2500000	GO:0002756	GO:BP	MyD88-independent toll-like receptor signaling pathway	16175	1267	GO:0002224
query_1	TRUE	0.0436577	16	887	4	0.0045096	0.2500000	GO:0043031	GO:BP	negative regulation of macrophage activation	16175	10486	GO:00026….
query_1	TRUE	0.0436577	34	887	6	0.0067644	0.1764706	GO:0010573	GO:BP	vascular endothelial growth factor production	16175	4226	GO:0001816
query_1	TRUE	0.0436577	66	887	9	0.0101466	0.1363636	GO:0055007	GO:BP	cardiac muscle cell differentiation	16175	14196	GO:00350….
query_1	TRUE	0.0436577	66	887	9	0.0101466	0.1363636	GO:0061614	GO:BP	miRNA transcription	16175	15585	GO:00063….
query_1	TRUE	0.0436577	16	887	4	0.0045096	0.2500000	GO:0050765	GO:BP	negative regulation of phagocytosis	16175	13239	GO:00069….
query_1	TRUE	0.0442897	55	887	8	0.0090192	0.1454545	GO:0006801	GO:BP	superoxide metabolic process	16175	2486	GO:0072593
query_1	TRUE	0.0444555	127	887	14	0.0157835	0.1102362	GO:0030041	GO:BP	actin filament polymerization	16175	6662	GO:00081….
query_1	TRUE	0.0452074	78	887	10	0.0112740	0.1282051	GO:2000628	GO:BP	regulation of miRNA metabolic process	16175	25910	GO:00105….
query_1	TRUE	0.0454330	90	887	11	0.0124014	0.1222222	GO:0044409	GO:BP	symbiont entry into host	16175	10994	GO:0051701
query_1	TRUE	0.0454330	90	887	11	0.0124014	0.1222222	GO:1904892	GO:BP	regulation of receptor signaling pathway via STAT	16175	24199	GO:00099….
query_1	TRUE	0.0456337	221	887	21	0.0236753	0.0950226	GO:0060537	GO:BP	muscle tissue development	16175	14726	GO:0009888
query_1	TRUE	0.0458420	235	887	22	0.0248027	0.0936170	GO:0071900	GO:BP	regulation of protein serine/threonine kinase activity	16175	16971	GO:0045859
query_1	TRUE	0.0468375	25	887	5	0.0056370	0.2000000	GO:0010669	GO:BP	epithelial structure maintenance	16175	4314	GO:0001894
query_1	TRUE	0.0468375	25	887	5	0.0056370	0.2000000	GO:0071404	GO:BP	cellular response to low-density lipoprotein particle stimulus	16175	16656	GO:00550….
query_1	TRUE	0.0468375	25	887	5	0.0056370	0.2000000	GO:1900745	GO:BP	positive regulation of p38MAPK cascade	16175	20917	GO:00380….
query_1	TRUE	0.0468375	25	887	5	0.0056370	0.2000000	GO:1902692	GO:BP	regulation of neuroblast proliferation	16175	22446	GO:00074….
query_1	TRUE	0.0473446	141	887	15	0.0169109	0.1063830	GO:0007254	GO:BP	JNK cascade	16175	2787	GO:0000165
query_1	TRUE	0.0479045	9	887	3	0.0033822	0.3333333	GO:0071636	GO:BP	positive regulation of transforming growth factor beta production	16175	16813	GO:00018….
query_1	TRUE	0.0479045	9	887	3	0.0033822	0.3333333	GO:2000564	GO:BP	regulation of CD8-positive, alpha-beta T cell proliferation	16175	25865	GO:00357….
query_1	TRUE	0.0479045	9	887	3	0.0033822	0.3333333	GO:0002423	GO:BP	natural killer cell mediated immune response to tumor cell	16175	946	GO:00022….
query_1	TRUE	0.0479045	9	887	3	0.0033822	0.3333333	GO:2000117	GO:BP	negative regulation of cysteine-type endopeptidase activity	16175	25466	GO:00109….
query_1	TRUE	0.0479045	9	887	3	0.0033822	0.3333333	GO:0002003	GO:BP	angiotensin maturation	16175	607	GO:00020….
query_1	TRUE	0.0479045	9	887	3	0.0033822	0.3333333	GO:0035771	GO:BP	interleukin-4-mediated signaling pathway	16175	9230	GO:00192….
query_1	TRUE	0.0479045	9	887	3	0.0033822	0.3333333	GO:0043312	GO:BP	neutrophil degranulation	16175	10620	GO:00022….
query_1	TRUE	0.0479045	9	887	3	0.0033822	0.3333333	GO:0032310	GO:BP	prostaglandin secretion	16175	7480	GO:00157….
query_1	TRUE	0.0479045	9	887	3	0.0033822	0.3333333	GO:0060054	GO:BP	positive regulation of epithelial cell proliferation involved in wound healing	16175	14316	GO:00420….
query_1	TRUE	0.0479045	9	887	3	0.0033822	0.3333333	GO:0035740	GO:BP	CD8-positive, alpha-beta T cell proliferation	16175	9205	GO:00360….
query_1	TRUE	0.0479045	9	887	3	0.0033822	0.3333333	GO:0035722	GO:BP	interleukin-12-mediated signaling pathway	16175	9192	GO:00192….
query_1	TRUE	0.0479045	9	887	3	0.0033822	0.3333333	GO:0002002	GO:BP	regulation of angiotensin levels in blood	16175	606	GO:00019….
query_1	TRUE	0.0479045	9	887	3	0.0033822	0.3333333	GO:0002420	GO:BP	natural killer cell mediated cytotoxicity directed against tumor cell target	16175	944	GO:00024….
query_1	TRUE	0.0483405	623	887	48	0.0541150	0.0770465	GO:0019725	GO:BP	cellular homeostasis	16175	6020	GO:0042592
query_1	TRUE	0.0486642	577	887	45	0.0507328	0.0779896	GO:0098655	GO:BP	monoatomic cation transmembrane transport	16175	18811	GO:00068….
query_1	TRUE	0.0491888	35	887	6	0.0067644	0.1714286	GO:0032660	GO:BP	regulation of interleukin-17 production	16175	7706	GO:00018….
query_1	TRUE	0.0491888	35	887	6	0.0067644	0.1714286	GO:0032620	GO:BP	interleukin-17 production	16175	7667	GO:0001816
query_1	TRUE	0.0000000	171	907	80	0.0882029	0.4678363	GO:0003823	GO:MF	antigen binding	17327	364	GO:0005488
query_1	TRUE	0.0000000	139	907	56	0.0617420	0.4028777	GO:0140375	GO:MF	immune receptor activity	17327	9378	GO:0038023
query_1	TRUE	0.0000000	1373	907	179	0.1973539	0.1303714	GO:0060089	GO:MF	molecular transducer activity	17327	7796	GO:0003674
query_1	TRUE	0.0000000	1373	907	179	0.1973539	0.1303714	GO:0038023	GO:MF	signaling receptor activity	17327	5035	GO:0060089
query_1	TRUE	0.0000000	1291	907	158	0.1742007	0.1223857	GO:0005102	GO:MF	signaling receptor binding	17327	1258	GO:0005515
query_1	TRUE	0.0000000	1152	907	139	0.1532525	0.1206597	GO:0004888	GO:MF	transmembrane signaling receptor activity	17327	1126	GO:0038023
query_1	TRUE	0.0000000	139	907	39	0.0429989	0.2805755	GO:0019955	GO:MF	cytokine binding	17327	3516	GO:0005515
query_1	TRUE	0.0000000	96	907	32	0.0352811	0.3333333	GO:0004896	GO:MF	cytokine receptor activity	17327	1129	GO:00048….
query_1	TRUE	0.0000000	32	907	15	0.0165380	0.4687500	GO:0023023	GO:MF	MHC protein complex binding	17327	3591	GO:0044877
query_1	TRUE	0.0000000	33	907	15	0.0165380	0.4545455	GO:0019956	GO:MF	chemokine binding	17327	3517	GO:0019955
query_1	TRUE	0.0000000	41	907	16	0.0176406	0.3902439	GO:0042605	GO:MF	peptide antigen binding	17327	5152	GO:00038….
query_1	TRUE	0.0000000	1013	907	102	0.1124587	0.1006910	GO:0044877	GO:MF	protein-containing complex binding	17327	5554	GO:0005488
query_1	TRUE	0.0000000	48	907	17	0.0187431	0.3541667	GO:0008009	GO:MF	chemokine activity	17327	1498	GO:00051….
query_1	TRUE	0.0000000	24	907	12	0.0132304	0.5000000	GO:0023026	GO:MF	MHC class II protein complex binding	17327	3594	GO:0023023
query_1	TRUE	0.0000000	24	907	12	0.0132304	0.5000000	GO:0019957	GO:MF	C-C chemokine binding	17327	3518	GO:0019956
query_1	TRUE	0.0000001	21	907	11	0.0121279	0.5238095	GO:0033691	GO:MF	sialic acid binding	17327	4377	GO:00314….
query_1	TRUE	0.0000002	10	907	8	0.0088203	0.8000000	GO:0019763	GO:MF	immunoglobulin receptor activity	17327	3450	GO:00048….
query_1	TRUE	0.0000002	72	907	19	0.0209482	0.2638889	GO:0042379	GO:MF	chemokine receptor binding	17327	5133	GO:00016….
query_1	TRUE	0.0000002	51	907	16	0.0176406	0.3137255	GO:0015026	GO:MF	coreceptor activity	17327	2240	GO:0038023
query_1	TRUE	0.0000003	18	907	10	0.0110254	0.5555556	GO:0019865	GO:MF	immunoglobulin binding	17327	3496	GO:0044877
query_1	TRUE	0.0000003	23	907	11	0.0121279	0.4782609	GO:0016493	GO:MF	C-C chemokine receptor activity	17327	2766	GO:0004950
query_1	TRUE	0.0000004	814	907	82	0.0904079	0.1007371	GO:0097367	GO:MF	carbohydrate derivative binding	17327	8493	GO:0005488
query_1	TRUE	0.0000005	35	907	13	0.0143330	0.3714286	GO:0042287	GO:MF	MHC protein binding	17327	5116	GO:0005102
query_1	TRUE	0.0000010	31	907	12	0.0132304	0.3870968	GO:0038187	GO:MF	pattern recognition receptor activity	17327	5062	GO:0038023
query_1	TRUE	0.0000010	235	907	35	0.0385888	0.1489362	GO:0005126	GO:MF	cytokine receptor binding	17327	1275	GO:0005102
query_1	TRUE	0.0000013	26	907	11	0.0121279	0.4230769	GO:0004950	GO:MF	chemokine receptor activity	17327	1171	GO:00016….
query_1	TRUE	0.0000013	26	907	11	0.0121279	0.4230769	GO:0001637	GO:MF	G protein-coupled chemoattractant receptor activity	17327	222	GO:0004930
query_1	TRUE	0.0000037	226	907	33	0.0363837	0.1460177	GO:0042277	GO:MF	peptide binding	17327	5109	GO:0005488
query_1	TRUE	0.0000040	143	907	25	0.0275634	0.1748252	GO:0005178	GO:MF	integrin binding	17327	1322	GO:00051….
query_1	TRUE	0.0000043	10	907	7	0.0077178	0.7000000	GO:0071723	GO:MF	lipopeptide binding	17327	8196	GO:00082….
query_1	TRUE	0.0000047	14	907	8	0.0088203	0.5714286	GO:0034987	GO:MF	immunoglobulin receptor binding	17327	4800	GO:0005102
query_1	TRUE	0.0000107	11	907	7	0.0077178	0.6363636	GO:0032393	GO:MF	MHC class I receptor activity	17327	4188	GO:00048….
query_1	TRUE	0.0000140	185	907	28	0.0308710	0.1513514	GO:0005125	GO:MF	cytokine activity	17327	1274	GO:0048018
query_1	TRUE	0.0000303	17	907	8	0.0088203	0.4705882	GO:0001614	GO:MF	purinergic nucleotide receptor activity	17327	213	GO:0016502
query_1	TRUE	0.0000321	373	907	43	0.0474090	0.1152815	GO:0004930	GO:MF	G protein-coupled receptor activity	17327	1154	GO:0004888
query_1	TRUE	0.0000321	110	907	20	0.0220507	0.1818182	GO:0030246	GO:MF	carbohydrate binding	17327	3633	GO:0005488
query_1	TRUE	0.0000321	1934	907	148	0.1631753	0.0765253	GO:0042802	GO:MF	identical protein binding	17327	5171	GO:0005515
query_1	TRUE	0.0000487	76	907	16	0.0176406	0.2105263	GO:0001540	GO:MF	amyloid-beta binding	17327	194	GO:00332….
query_1	TRUE	0.0000749	19	907	8	0.0088203	0.4210526	GO:0016502	GO:MF	nucleotide receptor activity	17327	2775	GO:0004888
query_1	TRUE	0.0001050	10	907	6	0.0066152	0.6000000	GO:0045028	GO:MF	G protein-coupled purinergic nucleotide receptor activity	17327	5557	GO:00016….
query_1	TRUE	0.0001380	48	907	12	0.0132304	0.2500000	GO:0048020	GO:MF	CCR chemokine receptor binding	17327	6730	GO:0042379
query_1	TRUE	0.0002109	7	907	5	0.0055127	0.7142857	GO:0032396	GO:MF	inhibitory MHC class I receptor activity	17327	4191	GO:0032393
query_1	TRUE	0.0003872	37	907	10	0.0110254	0.2702703	GO:0004715	GO:MF	non-membrane spanning protein tyrosine kinase activity	17327	986	GO:0004713
query_1	TRUE	0.0005010	166	907	23	0.0253583	0.1385542	GO:0005201	GO:MF	extracellular matrix structural constituent	17327	1331	GO:0005198
query_1	TRUE	0.0005022	8	907	5	0.0055127	0.6250000	GO:0032395	GO:MF	MHC class II receptor activity	17327	4190	GO:00048….
query_1	TRUE	0.0006119	436	907	44	0.0485116	0.1009174	GO:0030545	GO:MF	signaling receptor regulator activity	17327	3712	GO:0098772
query_1	TRUE	0.0006479	664	907	60	0.0661521	0.0903614	GO:0008289	GO:MF	lipid binding	17327	1623	GO:0005488
query_1	TRUE	0.0006483	397	907	41	0.0452040	0.1032746	GO:0048018	GO:MF	receptor ligand activity	17327	6728	GO:00051….
query_1	TRUE	0.0006989	332	907	36	0.0396913	0.1084337	GO:0003779	GO:MF	actin binding	17327	358	GO:0008092
query_1	TRUE	0.0007034	126	907	19	0.0209482	0.1507937	GO:0002020	GO:MF	protease binding	17327	287	GO:0019899
query_1	TRUE	0.0008151	402	907	41	0.0452040	0.1019900	GO:0030546	GO:MF	signaling receptor activator activity	17327	3713	GO:00305….
query_1	TRUE	0.0010976	262	907	30	0.0330761	0.1145038	GO:0001664	GO:MF	G protein-coupled receptor binding	17327	231	GO:0005102
query_1	TRUE	0.0017564	10	907	5	0.0055127	0.5000000	GO:0005031	GO:MF	tumor necrosis factor receptor activity	17327	1233	GO:0005035
query_1	TRUE	0.0022556	6	907	4	0.0044101	0.6666667	GO:0023029	GO:MF	MHC class Ib protein binding	17327	3597	GO:0042287
query_1	TRUE	0.0024323	162	907	21	0.0231533	0.1296296	GO:0005539	GO:MF	glycosaminoglycan binding	17327	1487	GO:0097367
query_1	TRUE	0.0026067	3	907	3	0.0033076	1.0000000	GO:0019770	GO:MF	IgG receptor activity	17327	3455	GO:0019763
query_1	TRUE	0.0026067	11	907	5	0.0055127	0.4545455	GO:0042608	GO:MF	T cell receptor binding	17327	5153	GO:00051….
query_1	TRUE	0.0026067	11	907	5	0.0055127	0.4545455	GO:0035325	GO:MF	Toll-like receptor binding	17327	4838	GO:0005102
query_1	TRUE	0.0026067	3	907	3	0.0033076	1.0000000	GO:0001791	GO:MF	IgM binding	17327	250	GO:0019865
query_1	TRUE	0.0026067	213	907	25	0.0275634	0.1173709	GO:0033218	GO:MF	amide binding	17327	4278	GO:0005488
query_1	TRUE	0.0026067	3	907	3	0.0033076	1.0000000	GO:0042010	GO:MF	interleukin-15 receptor activity	17327	5075	GO:0004896
query_1	TRUE	0.0026067	3	907	3	0.0033076	1.0000000	GO:0019767	GO:MF	IgE receptor activity	17327	3452	GO:0019763
query_1	TRUE	0.0026067	3	907	3	0.0033076	1.0000000	GO:0004911	GO:MF	interleukin-2 receptor activity	17327	1141	GO:0004896
query_1	TRUE	0.0026067	3	907	3	0.0033076	1.0000000	GO:0019976	GO:MF	interleukin-2 binding	17327	3531	GO:00198….
query_1	TRUE	0.0026067	11	907	5	0.0055127	0.4545455	GO:0001851	GO:MF	complement component C3b binding	17327	258	GO:00018….
query_1	TRUE	0.0032056	40	907	9	0.0099228	0.2250000	GO:0001784	GO:MF	phosphotyrosine residue binding	17327	246	GO:0045309
query_1	TRUE	0.0035518	930	907	74	0.0815877	0.0795699	GO:0140677	GO:MF	molecular function activator activity	17327	9477	GO:0098772
query_1	TRUE	0.0038013	18	907	6	0.0066152	0.3333333	GO:0045236	GO:MF	CXCR chemokine receptor binding	17327	5581	GO:0042379
query_1	TRUE	0.0038365	7	907	4	0.0044101	0.5714286	GO:0042289	GO:MF	MHC class II protein binding	17327	5118	GO:0042287
query_1	TRUE	0.0038365	7	907	4	0.0044101	0.5714286	GO:0046977	GO:MF	TAP binding	17327	5767	GO:0005515
query_1	TRUE	0.0038365	12	907	5	0.0055127	0.4166667	GO:0004126	GO:MF	cytidine deaminase activity	17327	598	GO:00168….
query_1	TRUE	0.0049849	15314	907	833	0.9184123	0.0543947	GO:0005488	GO:MF	binding	17327	1460	GO:0003674
query_1	TRUE	0.0049849	126	907	17	0.0187431	0.1349206	GO:0004252	GO:MF	serine-type endopeptidase activity	17327	653	GO:00041….
query_1	TRUE	0.0056300	13	907	5	0.0055127	0.3846154	GO:0005035	GO:MF	death receptor activity	17327	1235	GO:0004888
query_1	TRUE	0.0058676	27	907	7	0.0077178	0.2592593	GO:0016814	GO:MF	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	17327	2950	GO:0016810
query_1	TRUE	0.0066980	118	907	16	0.0176406	0.1355932	GO:0004713	GO:MF	protein tyrosine kinase activity	17327	984	GO:0004672
query_1	TRUE	0.0067817	8	907	4	0.0044101	0.5000000	GO:0042609	GO:MF	CD4 receptor binding	17327	5154	GO:0005102
query_1	TRUE	0.0082433	4	907	3	0.0033076	0.7500000	GO:0035663	GO:MF	Toll-like receptor 2 binding	17327	4894	GO:0035325
query_1	TRUE	0.0082433	4	907	3	0.0033076	0.7500000	GO:0046978	GO:MF	TAP1 binding	17327	5768	GO:0046977
query_1	TRUE	0.0082515	21	907	6	0.0066152	0.2857143	GO:0001846	GO:MF	opsonin binding	17327	253	GO:0005515
query_1	TRUE	0.0132343	31	907	7	0.0077178	0.2258065	GO:0042169	GO:MF	SH2 domain binding	17327	5105	GO:0019904
query_1	TRUE	0.0132343	31	907	7	0.0077178	0.2258065	GO:0019239	GO:MF	deaminase activity	17327	3442	GO:0016810
query_1	TRUE	0.0149366	16	907	5	0.0055127	0.3125000	GO:0042834	GO:MF	peptidoglycan binding	17327	5178	GO:0005539
query_1	TRUE	0.0167402	10	907	4	0.0044101	0.4000000	GO:0033550	GO:MF	MAP kinase tyrosine phosphatase activity	17327	4365	GO:00047….
query_1	TRUE	0.0167402	10	907	4	0.0044101	0.4000000	GO:0008330	GO:MF	protein tyrosine/threonine phosphatase activity	17327	1639	GO:0004721
query_1	TRUE	0.0167402	10	907	4	0.0044101	0.4000000	GO:0017017	GO:MF	MAP kinase tyrosine/serine/threonine phosphatase activity	17327	3058	GO:00081….
query_1	TRUE	0.0168227	5	907	3	0.0033076	0.6000000	GO:0030883	GO:MF	endogenous lipid antigen binding	17327	3834	GO:0030882
query_1	TRUE	0.0168227	5	907	3	0.0033076	0.6000000	GO:0031730	GO:MF	CCR5 chemokine receptor binding	17327	3967	GO:0048020
query_1	TRUE	0.0168227	5	907	3	0.0033076	0.6000000	GO:0048248	GO:MF	CXCR3 chemokine receptor binding	17327	6744	GO:0045236
query_1	TRUE	0.0168227	5	907	3	0.0033076	0.6000000	GO:0051373	GO:MF	FATZ binding	17327	7444	GO:0008092
query_1	TRUE	0.0168227	5	907	3	0.0033076	0.6000000	GO:0030882	GO:MF	lipid antigen binding	17327	3833	GO:00038….
query_1	TRUE	0.0168227	5	907	3	0.0033076	0.6000000	GO:0001875	GO:MF	lipopolysaccharide immune receptor activity	17327	275	GO:0038187
query_1	TRUE	0.0168227	5	907	3	0.0033076	0.6000000	GO:0030884	GO:MF	exogenous lipid antigen binding	17327	3835	GO:0030882
query_1	TRUE	0.0172559	52	907	9	0.0099228	0.1730769	GO:0045309	GO:MF	protein phosphorylated amino acid binding	17327	5593	GO:0051219
query_1	TRUE	0.0185631	680	907	54	0.0595369	0.0794118	GO:0042803	GO:MF	protein homodimerization activity	17327	5172	GO:00428….
query_1	TRUE	0.0185631	25	907	6	0.0066152	0.2400000	GO:0001848	GO:MF	complement binding	17327	255	GO:0005515
query_1	TRUE	0.0185631	25	907	6	0.0066152	0.2400000	GO:0001618	GO:MF	virus receptor activity	17327	215	GO:0140272
query_1	TRUE	0.0216062	110	907	14	0.0154355	0.1272727	GO:0008201	GO:MF	heparin binding	17327	1590	GO:00055….
query_1	TRUE	0.0229774	148	907	17	0.0187431	0.1148649	GO:0008236	GO:MF	serine-type peptidase activity	17327	1596	GO:00082….
query_1	TRUE	0.0230842	174	907	19	0.0209482	0.1091954	GO:0061134	GO:MF	peptidase regulator activity	17327	7812	GO:0030234
query_1	TRUE	0.0238945	55	907	9	0.0099228	0.1636364	GO:0038024	GO:MF	cargo receptor activity	17327	5036	GO:0003674
query_1	TRUE	0.0238945	1745	907	118	0.1300992	0.0676218	GO:0098772	GO:MF	molecular function regulator activity	17327	8575	GO:0003674
query_1	TRUE	0.0266373	27	907	6	0.0066152	0.2222222	GO:0140272	GO:MF	exogenous protein binding	17327	9338	GO:0005515
query_1	TRUE	0.0266373	138	907	16	0.0176406	0.1159420	GO:0061135	GO:MF	endopeptidase regulator activity	17327	7813	GO:0061134
query_1	TRUE	0.0268630	151	907	17	0.0187431	0.1125828	GO:0017171	GO:MF	serine hydrolase activity	17327	3121	GO:0016787
query_1	TRUE	0.0283700	6	907	3	0.0033076	0.5000000	GO:0031726	GO:MF	CCR1 chemokine receptor binding	17327	3963	GO:0048020
query_1	TRUE	0.0284529	2	907	2	0.0022051	1.0000000	GO:0070080	GO:MF	titin Z domain binding	17327	8021	GO:0019904
query_1	TRUE	0.0284529	2	907	2	0.0022051	1.0000000	GO:0004666	GO:MF	prostaglandin-endoperoxide synthase activity	17327	953	GO:0016705
query_1	TRUE	0.0284529	2	907	2	0.0022051	1.0000000	GO:0004917	GO:MF	interleukin-7 receptor activity	17327	1146	GO:0004896
query_1	TRUE	0.0284529	12	907	4	0.0044101	0.3333333	GO:0097493	GO:MF	structural molecule activity conferring elasticity	17327	8500	GO:0005198
query_1	TRUE	0.0284529	2	907	2	0.0022051	1.0000000	GO:0019772	GO:MF	low-affinity IgG receptor activity	17327	3457	GO:0019770
query_1	TRUE	0.0284529	2	907	2	0.0022051	1.0000000	GO:0031732	GO:MF	CCR7 chemokine receptor binding	17327	3969	GO:0048020
query_1	TRUE	0.0284529	2	907	2	0.0022051	1.0000000	GO:0042008	GO:MF	interleukin-18 receptor activity	17327	5073	GO:0004896
query_1	TRUE	0.0284529	2	907	2	0.0022051	1.0000000	GO:0015433	GO:MF	ABC-type peptide antigen transporter activity	17327	2504	GO:0015440
query_1	TRUE	0.0369303	13	907	4	0.0044101	0.3076923	GO:0042288	GO:MF	MHC class I protein binding	17327	5117	GO:0042287
query_1	TRUE	0.0369303	13	907	4	0.0044101	0.3076923	GO:0089720	GO:MF	caspase binding	17327	8369	GO:0002020
query_1	TRUE	0.0369303	13	907	4	0.0044101	0.3076923	GO:0031432	GO:MF	titin binding	17327	3893	GO:0008092
query_1	TRUE	0.0382599	326	907	29	0.0319735	0.0889571	GO:0004175	GO:MF	endopeptidase activity	17327	642	GO:0008233
query_1	TRUE	0.0421528	7	907	3	0.0033076	0.4285714	GO:0043120	GO:MF	tumor necrosis factor binding	17327	5240	GO:0019955
query_1	TRUE	0.0421528	7	907	3	0.0033076	0.4285714	GO:0005021	GO:MF	vascular endothelial growth factor receptor activity	17327	1228	GO:0004714
query_1	TRUE	0.0422326	40	907	7	0.0077178	0.1750000	GO:0043028	GO:MF	cysteine-type endopeptidase regulator activity involved in apoptotic process	17327	5235	GO:0030234
query_1	TRUE	0.0471633	14	907	4	0.0044101	0.2857143	GO:0016004	GO:MF	phospholipase activator activity	17327	2647	GO:0060229
query_1	TRUE	0.0471633	22	907	5	0.0055127	0.2272727	GO:0016702	GO:MF	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	17327	2860	GO:00167….
query_1	TRUE	0.0495985	190	907	19	0.0209482	0.1000000	GO:0051015	GO:MF	actin filament binding	17327	7405	GO:00037….
query_1	TRUE	0.0000000	291	498	68	0.1365462	0.2336770	KEGG:04060	KEGG	Cytokine-cytokine receptor interaction	8484	253	KEGG:00000
query_1	TRUE	0.0000000	92	498	38	0.0763052	0.4130435	KEGG:04640	KEGG	Hematopoietic cell lineage	8484	333	KEGG:00000
query_1	TRUE	0.0000000	98	498	37	0.0742972	0.3775510	KEGG:04061	KEGG	Viral protein interaction with cytokine and cytokine receptor	8484	254	KEGG:00000
query_1	TRUE	0.0000000	153	498	45	0.0903614	0.2941176	KEGG:04514	KEGG	Cell adhesion molecules	8484	315	KEGG:00000
query_1	TRUE	0.0000000	190	498	47	0.0943775	0.2473684	KEGG:04062	KEGG	Chemokine signaling pathway	8484	255	KEGG:00000
query_1	TRUE	0.0000000	86	498	31	0.0622490	0.3604651	KEGG:05150	KEGG	Staphylococcus aureus infection	8484	439	KEGG:00000
query_1	TRUE	0.0000000	72	498	28	0.0562249	0.3888889	KEGG:05140	KEGG	Leishmaniasis	8484	433	KEGG:00000
query_1	TRUE	0.0000000	147	498	39	0.0783133	0.2653061	KEGG:04145	KEGG	Phagosome	8484	281	KEGG:00000
query_1	TRUE	0.0000000	37	498	20	0.0401606	0.5405405	KEGG:05340	KEGG	Primary immunodeficiency	8484	488	KEGG:00000
query_1	TRUE	0.0000000	37	498	20	0.0401606	0.5405405	KEGG:05332	KEGG	Graft-versus-host disease	8484	487	KEGG:00000
query_1	TRUE	0.0000000	132	498	36	0.0722892	0.2727273	KEGG:04380	KEGG	Osteoclast differentiation	8484	309	KEGG:00000
query_1	TRUE	0.0000000	34	498	19	0.0381526	0.5588235	KEGG:05330	KEGG	Allograft rejection	8484	486	KEGG:00000
query_1	TRUE	0.0000000	40	498	19	0.0381526	0.4750000	KEGG:04940	KEGG	Type I diabetes mellitus	8484	394	KEGG:00000
query_1	TRUE	0.0000000	105	498	29	0.0582329	0.2761905	KEGG:04659	KEGG	Th17 cell differentiation	8484	337	KEGG:00000
query_1	TRUE	0.0000000	175	498	38	0.0763052	0.2171429	KEGG:05152	KEGG	Tuberculosis	8484	440	KEGG:00000
query_1	TRUE	0.0000000	62	498	22	0.0441767	0.3548387	KEGG:05321	KEGG	Inflammatory bowel disease	8484	483	KEGG:00000
query_1	TRUE	0.0000000	88	498	26	0.0522088	0.2954545	KEGG:05323	KEGG	Rheumatoid arthritis	8484	485	KEGG:00000
query_1	TRUE	0.0000000	124	498	31	0.0622490	0.2500000	KEGG:04650	KEGG	Natural killer cell mediated cytotoxicity	8484	334	KEGG:00000
query_1	TRUE	0.0000000	102	498	28	0.0562249	0.2745098	KEGG:04064	KEGG	NF-kappa B signaling pathway	8484	256	KEGG:00000
query_1	TRUE	0.0000000	69	498	23	0.0461847	0.3333333	KEGG:04612	KEGG	Antigen processing and presentation	8484	322	KEGG:00000
query_1	TRUE	0.0000000	89	498	26	0.0522088	0.2921348	KEGG:04658	KEGG	Th1 and Th2 cell differentiation	8484	336	KEGG:00000
query_1	TRUE	0.0000000	49	498	19	0.0381526	0.3877551	KEGG:05320	KEGG	Autoimmune thyroid disease	8484	482	KEGG:00000
query_1	TRUE	0.0000000	81	498	24	0.0481928	0.2962963	KEGG:04662	KEGG	B cell receptor signaling pathway	8484	339	KEGG:00000
query_1	TRUE	0.0000000	27	498	14	0.0281124	0.5185185	KEGG:05310	KEGG	Asthma	8484	481	KEGG:00000
query_1	TRUE	0.0000000	198	498	36	0.0722892	0.1818182	KEGG:05169	KEGG	Epstein-Barr virus infection	8484	450	KEGG:00000
query_1	TRUE	0.0000000	44	498	16	0.0321285	0.3636364	KEGG:04672	KEGG	Intestinal immune network for IgA production	8484	344	KEGG:00000
query_1	TRUE	0.0000000	63	498	19	0.0381526	0.3015873	KEGG:05416	KEGG	Viral myocarditis	8484	493	KEGG:00000
query_1	TRUE	0.0000000	86	498	22	0.0441767	0.2558140	KEGG:04610	KEGG	Complement and coagulation cascades	8484	320	KEGG:00000
query_1	TRUE	0.0000001	113	498	25	0.0502008	0.2212389	KEGG:04668	KEGG	TNF signaling pathway	8484	342	KEGG:00000
query_1	TRUE	0.0000001	49	498	16	0.0321285	0.3265306	KEGG:05144	KEGG	Malaria	8484	436	KEGG:00000
query_1	TRUE	0.0000001	108	498	24	0.0481928	0.2222222	KEGG:05145	KEGG	Toxoplasmosis	8484	437	KEGG:00000
query_1	TRUE	0.0000001	182	498	32	0.0642570	0.1758242	KEGG:04621	KEGG	NOD-like receptor signaling pathway	8484	326	KEGG:00000
query_1	TRUE	0.0000003	218	498	35	0.0702811	0.1605505	KEGG:05166	KEGG	Human T-cell leukemia virus 1 infection	8484	447	KEGG:00000
query_1	TRUE	0.0000004	76	498	19	0.0381526	0.2500000	KEGG:05133	KEGG	Pertussis	8484	430	KEGG:00000
query_1	TRUE	0.0000009	167	498	29	0.0582329	0.1736527	KEGG:05164	KEGG	Influenza A	8484	445	KEGG:00000
query_1	TRUE	0.0000011	132	498	25	0.0502008	0.1893939	KEGG:05322	KEGG	Systemic lupus erythematosus	8484	484	KEGG:00000
query_1	TRUE	0.0000094	119	498	22	0.0441767	0.1848739	KEGG:04660	KEGG	T cell receptor signaling pathway	8484	338	KEGG:00000
query_1	TRUE	0.0000094	101	498	20	0.0401606	0.1980198	KEGG:05142	KEGG	Chagas disease	8484	434	KEGG:00000
query_1	TRUE	0.0000102	188	498	29	0.0582329	0.1542553	KEGG:04613	KEGG	Neutrophil extracellular trap formation	8484	323	KEGG:00000
query_1	TRUE	0.0000113	210	498	31	0.0622490	0.1476190	KEGG:05170	KEGG	Human immunodeficiency virus 1 infection	8484	451	KEGG:00000
query_1	TRUE	0.0000195	56	498	14	0.0281124	0.2500000	KEGG:05134	KEGG	Legionellosis	8484	431	KEGG:00000
query_1	TRUE	0.0000269	36	498	11	0.0220884	0.3055556	KEGG:05143	KEGG	African trypanosomiasis	8484	435	KEGG:00000
query_1	TRUE	0.0000305	138	498	23	0.0461847	0.1666667	KEGG:05162	KEGG	Measles	8484	443	KEGG:00000
query_1	TRUE	0.0000444	214	498	30	0.0602410	0.1401869	KEGG:05417	KEGG	Lipid and atherosclerosis	8484	494	KEGG:00000
query_1	TRUE	0.0000552	114	498	20	0.0401606	0.1754386	KEGG:04670	KEGG	Leukocyte transendothelial migration	8484	343	KEGG:00000
query_1	TRUE	0.0000753	136	498	22	0.0441767	0.1617647	KEGG:05135	KEGG	Yersinia infection	8484	432	KEGG:00000
query_1	TRUE	0.0001186	101	498	18	0.0361446	0.1782178	KEGG:05146	KEGG	Amoebiasis	8484	438	KEGG:00000
query_1	TRUE	0.0001754	104	498	18	0.0361446	0.1730769	KEGG:04625	KEGG	C-type lectin receptor signaling pathway	8484	330	KEGG:00000
query_1	TRUE	0.0002239	106	498	18	0.0361446	0.1698113	KEGG:04620	KEGG	Toll-like receptor signaling pathway	8484	325	KEGG:00000
query_1	TRUE	0.0002351	223	498	29	0.0582329	0.1300448	KEGG:05163	KEGG	Human cytomegalovirus infection	8484	444	KEGG:00000
query_1	TRUE	0.0002818	89	498	16	0.0321285	0.1797753	KEGG:05235	KEGG	PD-L1 expression and PD-1 checkpoint pathway in cancer	8484	480	KEGG:00000
query_1	TRUE	0.0002822	192	498	26	0.0522088	0.1354167	KEGG:05202	KEGG	Transcriptional misregulation in cancer	8484	454	KEGG:00000
query_1	TRUE	0.0002977	5	498	4	0.0080321	0.8000000	KEGG:03260	KEGG	Virion - Human immunodeficiency virus	8484	226	KEGG:00000
query_1	TRUE	0.0003248	194	498	26	0.0522088	0.1340206	KEGG:05167	KEGG	Kaposi sarcoma-associated herpesvirus infection	8484	448	KEGG:00000
query_1	TRUE	0.0003629	82	498	15	0.0301205	0.1829268	KEGG:04623	KEGG	Cytosolic DNA-sensing pathway	8484	328	KEGG:00000
query_1	TRUE	0.0005357	156	498	22	0.0441767	0.1410256	KEGG:04148	KEGG	Efferocytosis	8484	283	KEGG:00000
query_1	TRUE	0.0009222	162	498	22	0.0441767	0.1358025	KEGG:04630	KEGG	JAK-STAT signaling pathway	8484	332	KEGG:00000
query_1	TRUE	0.0009418	231	498	28	0.0562249	0.1212121	KEGG:05171	KEGG	Coronavirus disease - COVID-19	8484	452	KEGG:00000
query_1	TRUE	0.0020782	96	498	15	0.0301205	0.1562500	KEGG:04666	KEGG	Fc gamma R-mediated phagocytosis	8484	341	KEGG:00000
query_1	TRUE	0.0041234	92	498	14	0.0281124	0.1521739	KEGG:04657	KEGG	IL-17 signaling pathway	8484	335	KEGG:00000
query_1	TRUE	0.0075793	67	498	11	0.0220884	0.1641791	KEGG:04664	KEGG	Fc epsilon RI signaling pathway	8484	340	KEGG:00000
query_1	TRUE	0.0106797	124	498	16	0.0321285	0.1290323	KEGG:04611	KEGG	Platelet activation	8484	321	KEGG:00000
query_1	TRUE	0.0107550	527	498	47	0.0943775	0.0891841	KEGG:05200	KEGG	Pathways in cancer	8484	453	KEGG:00000
query_1	TRUE	0.0132968	62	498	10	0.0200803	0.1612903	KEGG:03250	KEGG	Viral life cycle - HIV-1	8484	223	KEGG:00000
query_1	TRUE	0.0232409	67	498	10	0.0200803	0.1492537	KEGG:05221	KEGG	Acute myeloid leukemia	8484	472	KEGG:00000
query_1	TRUE	0.0246922	210	498	22	0.0441767	0.1047619	KEGG:04015	KEGG	Rap1 signaling pathway	8484	248	KEGG:00000
query_1	TRUE	0.0246922	356	498	33	0.0662651	0.0926966	KEGG:04151	KEGG	PI3K-Akt signaling pathway	8484	285	KEGG:00000
query_1	TRUE	0.0461418	158	498	17	0.0341365	0.1075949	KEGG:04217	KEGG	Necroptosis	8484	294	KEGG:00000

Notably, we see that the pathways found to be enriched in the upregulated gene set is similar to that in the combined gene set, which mirrors our differential gene expression analysis where we saw that most of the differentially expressed genes were upregulated in caABMR. These genes are mostly immune-related pathways from GO:BP, which reflects the elevated immune response genes that are activated during chronic rejection.

Downregulated Gene Set

gprofiler_output <- gprofiler2::gost(query = downregulated_genes, 
                                     significant = TRUE,
                                     exclude_iea = TRUE,
                                     correction_method = "fdr", 
                                     organism = "hsapiens", 
                                     source = c("GO:MF", "GO:BP", "KEGG"))

gprofiler_down <- as.data.frame(gprofiler_output$result)
knitr::kable(gprofiler_down, type="html") %>% 
  kableExtra::scroll_box(width = "600px", height = "200px")

query	significant	p_value	term_size	query_size	intersection_size	precision	recall	term_id	source	term_name	effective_domain_size	source_order	parents
query_1	TRUE	0.0286806	110	28	3	0.1071429	0.0272727	GO:0030246	GO:MF	carbohydrate binding	17327	3633	GO:0005488
query_1	TRUE	0.0286806	120	28	3	0.1071429	0.0250000	GO:0019209	GO:MF	kinase activator activity	17327	3434	GO:00080….
query_1	TRUE	0.0286806	2037	28	10	0.3571429	0.0049092	GO:0036094	GO:MF	small molecule binding	17327	4932	GO:0005488
query_1	TRUE	0.0286806	1834	28	10	0.3571429	0.0054526	GO:0043167	GO:MF	ion binding	17327	5248	GO:0036094
query_1	TRUE	0.0286806	372	28	5	0.1785714	0.0134409	GO:0005509	GO:MF	calcium ion binding	17327	1471	GO:0046872
query_1	TRUE	0.0286806	116	28	3	0.1071429	0.0258621	GO:0030295	GO:MF	protein kinase activator activity	17327	3658	GO:00192….
query_1	TRUE	0.0371674	1	28	1	0.0357143	1.0000000	GO:0004760	GO:MF	L-serine-pyruvate transaminase activity	17327	1022	GO:0008483
query_1	TRUE	0.0371674	1	28	1	0.0357143	1.0000000	GO:0047837	GO:MF	D-xylose 1-dehydrogenase (NADP+) activity	17327	6571	GO:0016616
query_1	TRUE	0.0445314	210	28	3	0.1071429	0.0142857	GO:0019887	GO:MF	protein kinase regulator activity	17327	3502	GO:0019207
query_1	TRUE	0.0445314	991	28	6	0.2142857	0.0060545	GO:0046872	GO:MF	metal ion binding	17327	5730	GO:0043169
query_1	TRUE	0.0445314	3	28	1	0.0357143	0.3333333	GO:0015196	GO:MF	L-tryptophan transmembrane transporter activity	17327	2367	GO:00151….
query_1	TRUE	0.0445314	57	28	2	0.0714286	0.0350877	GO:0001786	GO:MF	phosphatidylserine binding	17327	248	GO:00055….
query_1	TRUE	0.0445314	46	28	2	0.0714286	0.0434783	GO:0005504	GO:MF	fatty acid binding	17327	1468	GO:00082….
query_1	TRUE	0.0445314	2	28	1	0.0357143	0.5000000	GO:0005128	GO:MF	erythropoietin receptor binding	17327	1277	GO:0005126
query_1	TRUE	0.0445314	3	28	1	0.0357143	0.3333333	GO:0004967	GO:MF	glucagon receptor activity	17327	1187	GO:0008528
query_1	TRUE	0.0445314	2	28	1	0.0357143	0.5000000	GO:0004421	GO:MF	hydroxymethylglutaryl-CoA synthase activity	17327	754	GO:0046912
query_1	TRUE	0.0445314	3	28	1	0.0357143	0.3333333	GO:0004346	GO:MF	glucose-6-phosphatase activity	17327	693	GO:0050309
query_1	TRUE	0.0445314	3	28	1	0.0357143	0.3333333	GO:0050309	GO:MF	sugar-terminal-phosphatase activity	17327	7056	GO:0050308
query_1	TRUE	0.0445314	3	28	1	0.0357143	0.3333333	GO:0008453	GO:MF	alanine-glyoxylate transaminase activity	17327	1703	GO:0008483
query_1	TRUE	0.0445314	46	28	2	0.0714286	0.0434783	GO:0005544	GO:MF	calcium-dependent phospholipid binding	17327	1491	GO:0005543
query_1	TRUE	0.0449550	1745	28	8	0.2857143	0.0045845	GO:0098772	GO:MF	molecular function regulator activity	17327	8575	GO:0003674
query_1	TRUE	0.0468808	75	28	2	0.0714286	0.0266667	GO:0033293	GO:MF	monocarboxylic acid binding	17327	4294	GO:0031406
query_1	TRUE	0.0468808	81	28	2	0.0714286	0.0246914	GO:0072341	GO:MF	modified amino acid binding	17327	8230	GO:0005488
query_1	TRUE	0.0468808	4	28	1	0.0357143	0.2500000	GO:0016997	GO:MF	alpha-sialidase activity	17327	3055	GO:0004553
query_1	TRUE	0.0468808	1092	28	6	0.2142857	0.0054945	GO:0043169	GO:MF	cation binding	17327	5250	GO:0043167
query_1	TRUE	0.0468808	5	28	1	0.0357143	0.2000000	GO:0046870	GO:MF	cadmium ion binding	17327	5728	GO:0046914
query_1	TRUE	0.0468808	74	28	2	0.0714286	0.0270270	GO:0016209	GO:MF	antioxidant activity	17327	2686	GO:0003674
query_1	TRUE	0.0468808	5	28	1	0.0357143	0.2000000	GO:0046912	GO:MF	acyltransferase activity, acyl groups converted into alkyl on transfer	17327	5740	GO:0016746
query_1	TRUE	0.0468808	501	28	4	0.1428571	0.0079840	GO:0008047	GO:MF	enzyme activator activity	17327	1512	GO:00302….
query_1	TRUE	0.0468808	4	28	1	0.0357143	0.2500000	GO:0004308	GO:MF	exo-alpha-sialidase activity	17327	662	GO:0016997
query_1	TRUE	0.0468808	1111	28	6	0.2142857	0.0054005	GO:0030234	GO:MF	enzyme regulator activity	17327	3631	GO:0098772
query_1	TRUE	0.0468808	242	28	3	0.1071429	0.0123967	GO:0019207	GO:MF	kinase regulator activity	17327	3432	GO:0030234

We see that there are fewer enriched gene sets when focussing on the genes downregulated in non-rejecting samples, which is again expected from our DE results before. Notably, the enriched gene sets are all from the “GO:MF” database and not from the “GO:BP” database, unlike the upregulated and combined results. In fact, when we focus on only the GO:BP database for ORA, we see that gprofiler does not return any significantly enriched gene sets.

gprofiler_output <- gprofiler2::gost(query = downregulated_genes, 
                                     significant = TRUE,
                                     exclude_iea = TRUE,
                                     correction_method = "fdr", 
                                     organism = "hsapiens", 
                                     source = c("GO:BP"))

## No results to show
## Please make sure that the organism is correct or set significant = FALSE

Interpretation

From our DE and ORA results, we see that there is an upregulation immune-related pathways and genes, particularly NK-cell-related and cytotoxic genes, which aligns with published literature on transplant rejection [10].

We have seen that the caABMR and non-rejecting samples separate distinctly based on gene expression, and the upregulated genes in caABMR are enriched in cytotoxic genes, pro-inflammatory molecules, and NK-specific genes. Similar results are observed in our ORA data, where there is an enrichment of immune-related pathways, particularly leukocyte activation pathways, which confirms the results found by the authors of the original paper [1]. However, the genes upregulated in the no-rejection dataset do not show enrichment in biological process gene set in the GO:BP dataset, and instead are enriched in several GO:MF molecular function gene sets which could shed light on the resting-state programs that are downregulated upon caABMR.

References

1. Shah Y, Yang H, Mueller FB, Li C, Rahim SEG, Varma E, et al. Transcriptomic signatures of chronic active antibody-mediated rejection deciphered by RNA sequencing of human kidney allografts. Kidney International. 2024;105:347–63.

2. Chen Y, Chen L, Lun AT, Baldoni PL, Smyth GK. edgeR 4.0: Powerful differential analysis of sequencing data with expanded functionality and improved support for small counts and larger datasets. bioRxiv. 2024;2024–01.

3. Ritchie ME, Phipson B, Wu D, Hu Y, Law CW, Shi W, et al. Limma powers differential expression analyses for RNA-sequencing and microarray studies. Nucleic acids research. 2015;43:e47–7.

4. Chen Y, McCarthy D, Ritchie M, Robinson M, Smyth G, Hall E. edgeR: Differential analysis of sequence read count data user’s guide. R Packag. 2020; June:1–121.

5. Slowikowski K. Ggrepel: Automatically position non-overlapping text labels with ’ggplot2’. 2024.

6. Wickham H. ggplot2: Elegant graphics for data analysis. Springer-Verlag New York; 2016.

7. Neuwirth E. RColorBrewer: ColorBrewer palettes. 2002.

8. Liis K, Uku R, Kuzmin I, Jaak V, Peterson H. gprofiler2–an r package for gene list functional enrichment analysis and namespace conversion toolset g: profiler. F1000Research. 2020;9.

9. Raudvere U, Kolberg L, Kuzmin I, Arak T, Adler P, Peterson H, et al. G: Profiler: A web server for functional enrichment analysis and conversions of gene lists (2019 update). Nucleic acids research. 2019;47:W191–8.

10. Garces JC, Giusti S, Staffeld-Coit C, Bohorquez H, Cohen AJ, Loss GE. Antibody-Mediated Rejection: A Review. Ochsner Journal. 2017;17:46–55.